Response to the letter to the editor by Tomoyuki Kawada, 'Coffee/tea consumption and depression: a risk assessment'.
PMID: 31964425 [PubMed - as supplied by publisher] (Source: The British Journal of Nutrition)
Source: The British Journal of Nutrition - January 22, 2020 Category: Nutrition Authors: Elstgeest LEM, Brouwer IA, Visser M Tags: Br J Nutr Source Type: research

Dietary intake from complementary feeding is associated with intestinal barrier function and environmental enteropathy in Brazilian children from the MAL-ED cohort study.
This study aimed to evaluate the relations between complementary feeding, intestinal barrier function, and environmental enteropathy (EE) in infants. Data from 233 children were obtained from the Brazilian site of the MAL-ED cohort study. Habitual dietary intake from complementary feeding was estimated using seven 24 h dietary recalls, from 9 to 15 months of age. Intestinal barrier function was assessed using the lactulose/mannitol test (L/M) and EE was determined as a composite measure using fecal biomarkers concentrations - alpha-1-antitrypsin, myeloperoxidase (MPO) and neopterin (NEO) at 15 months of age. The nutrient a...
Source: The British Journal of Nutrition - January 22, 2020 Category: Nutrition Authors: Costa PN, Soares AM, Filho JQ, Junior FS, Ambikapathi R, Rogawski McQuade ET, Guerrant RL, Caulfield LE, Lima AAM, Maciel BLL Tags: Br J Nutr Source Type: research

Early energy restriction in premature infants and bronchopulmonary dysplasia: A cohort study.
The objective of this study is to determine the existence of association between BPD in VLBW and energy intake during the first week of life. We recorded in a retrospective cohort study the intake of enteral and parenteral macronutrients during this period, by examining the nutritional and clinical history of 450 VLBW newborns admitted to the neonatal intensive care unit. After applying the relevant exclusion criteria, data for 389 VLBW infants were analysed, of whom 159 developed some degree of BPD. Among the newborns with BPD, energy and lipid intake was significantly lower, and fluid intake was significantly higher. The...
Source: The British Journal of Nutrition - January 22, 2020 Category: Nutrition Authors: Uberos J, Jimenez-Montilla S, Molina-Oya M, Luis García-Serrano J Tags: Br J Nutr Source Type: research

Daily intake of non-fried potato does not affect markers of glycemia and is associated with better diet quality compared to refined grains: A randomized, crossover study in healthy adults.
Abstract Epidemiologic studies suggest that consumption of potatoes is associated with increased risk of cardiometabolic diseases. However, few clinical trials have empirically tested these observational findings. The aim of this single-blind, randomized, crossover study was to evaluate the effect of daily potato consumption, compared to refined grains, on risk factors for cardiometabolic diseases. It was hypothesized that no difference in cardiometabolic endpoints would be detected between conditions, but diet quality would improve with potato consumption. Healthy participants on self-selected diets received one ...
Source: The British Journal of Nutrition - January 22, 2020 Category: Nutrition Authors: Johnston EA, Petersen KS, Kris-Etherton PM Tags: Br J Nutr Source Type: research

Maternal gestational diabetes and infant feeding, nutrition and growth: a systematic review and meta-analysis.
Abstract Gestational diabetes mellitus (GDM) is a major health problem, with increased risks of obesity and diabetes in offspring. However, little is known of the effect of GDM on infant feeding, nutrition and growth, and whether these factors play a role in mediating these risks. We systematically reviewed evidence for the effect of GDM on infant feeding, nutrition and growth. We searched MEDLINE, Web-of-Science, EMBASE, CINAHL and CENTRAL for studies that reported outcomes in infants
Source: The British Journal of Nutrition - January 22, 2020 Category: Nutrition Authors: Manerkar K, Harding J, Conlon C, McKinlay C Tags: Br J Nutr Source Type: research

The utility of anthopometric indicators to identify cardiovascular risk factors in vietnamese children.
THE UTILITY OF ANTHOPOMETRIC INDICATORS TO IDENTIFY CARDIOVASCULAR RISK FACTORS IN VIETNAMESE CHILDREN. Br J Nutr. 2020 Jan 22;:1-29 Authors: Mai TMT, Gallegos D, Jones L, Tran QC, Tran TMH, van der Pols JC Abstract Body mass index (BMI), waist circumference (WC), and waist-to-height ratio (WHtR) can be used for discriminating children and adolescents at risk of cardiovascular diseases. However, consensus on how to use these anthropometric indicators is lacking for children and adolescents in Asia. Discrete criteria are promoted internationally, but continuous variables could be used. Data from a surv...
Source: The British Journal of Nutrition - January 22, 2020 Category: Nutrition Authors: Mai TMT, Gallegos D, Jones L, Tran QC, Tran TMH, van der Pols JC Tags: Br J Nutr Source Type: research

Lactational changes of fatty acids and fat-soluble antioxidants in human milk from healthy Chinese mothers.
This study aimed to quantify the composition of fatty acids, tocopherols and carotenoids in human milk, with special emphasis on the lactational changes. Colostrum, transitional, and mature milk samples were collected longitudinally from the same 42 healthy, well-nourished Chinese mothers. Fatty acids were quantified by gas chromatography with carotenoids (carotenes and xanthophylls) and tocopherols (α-, γ-tocopherol) determined by high-performance liquid chromatography. Total fatty acids content increased from 15.09 g/L in colostrum to 32.57 g/L in mature milk with the percentages of DHA and ARA decreased. The...
Source: The British Journal of Nutrition - January 22, 2020 Category: Nutrition Authors: Wu K, Zhu J, Zhou L, Shen L, Mao Y, Zhao Y, Gao R, Lou Z, Cai M, Wang B Tags: Br J Nutr Source Type: research

The association between milk consumption and metabolic syndrome: A cross-sectional study of the residents of Suzhou, China and a meta-analysis.
Abstract The association between milk consumption and metabolic syndrome remains inconclusive, and the data from Chinese populations are scarce. We conducted a cross-sectional study to investigate the association between milk consumption and metabolic syndrome and its components among the residents of Suzhou Industrial Park, Suzhou, China. A total of 5149 participants were included in the final analysis. A logistic regression model was applied to estimate the odds ratios (OR) and 95% confidence intervals (CIs) for the prevalence of metabolic syndrome and its components according to milk consumption. In addition, t...
Source: The British Journal of Nutrition - January 22, 2020 Category: Nutrition Authors: Hidayat K, Yu LG, Yang JR, Zhang XY, Zhou H, Shi YJ, Liu B, Qin LQ Tags: Br J Nutr Source Type: research

Adherence to the Dietary Approach to Stop Hypertension (DASH) and hypertension risk: results of the Longitudinal Study of Adult Health (ELSA-Brasil).
tti L Abstract We investigated whether high adherence to the DASH diet was independently associated with lower risk of incident hypertension. Participants included 5,632 adults, without hypertension at the baseline (2008-2010) of the Longitudinal Study of Adult Health (ELSA-Brasil), who took part in the second follow-up visit (2012-2014). Adherence to the DASH diet was estimated at baseline using a score based on 8 food items (final scores from 8 to 40 points), categorized as high adherence (≥30 points, or ≥75%) and low adherence (
Source: The British Journal of Nutrition - January 21, 2020 Category: Nutrition Authors: Francisco SC, Araújo LF, Griep RH, Chor D, Molina MDCB, Mil JG, Bensenor IM, Matos SMA, Barreto SM, Giatti L Tags: Br J Nutr Source Type: research

Vitamin D related genes and cardiometabolic markers in healthy children: a Mendelian randomization study.
Abstract Observational studies in adults and children show associations between low serum 25-hydroxyvitamin D (25(OH)D) and an adverse cardiometabolic risk profile. This Mendelian randomization study examines associations between cardiometabolic markers in children and single nucleotide polymorphisms (SNPs) in genes related to vitamin D metabolism and action. In 699 healthy 8-11-year-old children, we genotyped SNPs in vitamin D-related genes (DHCR7 (rs12785878, rs3829251); GC (rs4588, rs7041, rs12512631); CYP2R1 (rs10741657, rs10500804, rs156292); CYP27B1 (rs10877012); CYP24A1 (rs2296241); VDR (rs757343, rs2228570...
Source: The British Journal of Nutrition - January 21, 2020 Category: Nutrition Authors: Lopez-Mayorga A, Hauger H, Petersen RA, Vogel U, Damsgaard CT, Lauritzen L Tags: Br J Nutr Source Type: research

Baseline diet modifies the effects of dietary change in the PREMIER Study.
Abstract The DASH eating pattern has been shown to reduce blood pressure (BP) in previous clinical trials. In the PREMIER study, an established behavioral intervention, with or without DASH, promoted greater weight loss than an advice-only control group, but effects of the DASH intervention on BP were weaker. In these analyses, PREMIER data were used to evaluate whether change in dairy or fruits and vegetable (FV) intake during the first six intervention months impacted changes in weight and/or BP. Study participants were classified as having low or high intakes of dairy (
Source: The British Journal of Nutrition - January 21, 2020 Category: Nutrition Authors: Pickering RT, Bradlee ML, Singer MR, Moore LL Tags: Br J Nutr Source Type: research

Salt need needs investigation.
Abstract Expensive and extensive studies on the epidemiology of excessive sodium intake and its pathology have been conducted over four decades. The resultant consensus that dietary sodium is toxic, as well as the contention that it is less so, ignore the root cause of the attractiveness of salted food. The extant hypotheses are that most sodium is infiltrated into our bodies via heavily salted industrialized food without our knowledge and that mere exposure early in life determines lifelong intake. However, these hypotheses are poorly evidenced and are meagre explanations for the comparable salt intake of people ...
Source: The British Journal of Nutrition - January 21, 2020 Category: Nutrition Authors: Leshem M Tags: Br J Nutr Source Type: research

Dietary taurine stimulates the hepatic biosynthesis of both bile acid and cholesterol in the marine teleost, tiger puffer (Takifugu rubripes).
In conclusion, dietary taurine stimulated the hepatic biosynthesis of both bile acid and cholesterol, and tended to regulate the lipid metabolism in multiple ways. PMID: 31959268 [PubMed - as supplied by publisher] (Source: The British Journal of Nutrition)
Source: The British Journal of Nutrition - January 21, 2020 Category: Nutrition Authors: Xu H, Zhang Q, Kim SK, Liao Z, Wei Y, Sun B, Jia L, Shuyan C, Liang M Tags: Br J Nutr Source Type: research

Intrauterine growth restriction induced by maternal low protein diet causes long-term alterations of thymic structure and function in adult male rat offspring.
This study investigates thymic structure, protein expression and cell selection process observed at postnatal day 180 (PND180) in male offspring of rats exposed to maternal low protein diet (mLPD) compared to control diet during gestation. The thymic index was lower in adult offspring exposed to mLPD (p
Source: The British Journal of Nutrition - January 21, 2020 Category: Nutrition Authors: Armengaud JB, Dennebouy Z, Labes D, Fumey C, Wilson A, Candotti F, Yzydorczyk C, Simeoni U Tags: Br J Nutr Source Type: research

Changes in fruit, vegetable, and fish consumption after statutory retirement: a prospective cohort study.
We examined whether the consumption of fruit and vegetables as well as fish changes after transition into statutory retirement. The data were derived from the prospective Helsinki Health Study. At phase 1 in 2000-2002, all participants were 40-60-year-old employees of the City of Helsinki, Finland (n 8960, response rate 67%). Follow-up surveys were conducted in 2007, 2012, and 2017 (response rates 79-83%). Using the 4 phases, we formed 3 nested cohorts in which the participants either continued working or moved to statutory retirement. The final analytical sample consisted of 6887 participants (14 357 observations). Freque...
Source: The British Journal of Nutrition - January 20, 2020 Category: Nutrition Authors: Ali-Kovero K, Pietiläinen O, Mauramo E, Jäppinen S, Rahkonen O, Lallukka T, Kanerva N Tags: Br J Nutr Source Type: research

Holly polyphenols alleviate intestinal inflammation and alter microbiota composition in lipopolysaccharide-challenged pigs.
Abstract The effect of holly polyphenols (HP) on intestinal inflammation and microbiota composition was evaluated in a piglet model of lipopolysaccharide (LPS)-induced intestinal injury. A total of 24 piglets were used in a 2 × 2 factorial design including diet type and LPS challenge. After 16 d of feeding with a basal diet supplemented with or without 250 mg/kg HP, pigs were challenged with LPS (100 μg/kg BW) or an equal volume of saline for 4 h, followed by analysis of disaccharidase activities, gene expression levels of several representative tight junction proteins and inflammatory mediators, the shor...
Source: The British Journal of Nutrition - January 13, 2020 Category: Nutrition Authors: Xu X, Hua H, Wang L, He P, Zhang L, Qin Q, Yu C, Wang X, Zhang G, Liu Y Tags: Br J Nutr Source Type: research

Night-restricted feeding of dairy cows modifies daily rhythms of feed intake, milk synthesis and plasma metabolites compared to day-restricted feeding.
The objective of this experiment was to determine if the time of feed intake modifies the daily patterns of milk synthesis, plasma metabolites, and body temperature in dairy cows. Sixteen lactating Holstein dairy cows were randomly assigned to one of two treatment sequences in a cross-over design with 17 d periods. Treatments included day-restricted feeding (DRF; feed available from 0700 to 2300 h) and night-restricted feeding (NRF; feed available from 1900 to 1100 h. Cows were milked every 6 h on the last 7 d of each period and blood samples were collected to represent every 4 h over the day. Peak milk yield was shifted f...
Source: The British Journal of Nutrition - January 8, 2020 Category: Nutrition Authors: Salfer IJ, Harvatine KJ Tags: Br J Nutr Source Type: research

Dietary intake of phloridzin from natural occurrence in foods.
Abstract Type 2 diabetes mellitus (T2DM) is one of the major diseases of our times. Besides being a considerable inconvenience for the patient, the associated healthcare expenses are tremendous. One of the cornerstones of T2DM prevention is a healthy diet, including a variety of fruits and vegetables. Apples are touted to have health benefits and the apple polyphenol phloridzin has gained interest in recent years as it can reduce intestinal sugar uptake by inhibition of the sodium/glucose cotransporter 1 (SGLT1). By researching the amount of phloridzin in different food sources and linking them to their consumptio...
Source: The British Journal of Nutrition - January 8, 2020 Category: Nutrition Authors: Niederberger KE, Tennant DR, Bellion P Tags: Br J Nutr Source Type: research

Interaction of recommended levels of physical activity and protein intake is associated with greater physical function, and lower fat mass in older women: Kuopio OSTPRE- Fracture Prevention Study.
Isanejad M Abstract The aim of the study was to investigate whether the interaction of physical activity (PA) and protein intake is associated with physical function (PF). The women from the Osteoporosis Risk Factor and Fracture Prevention Study (OSTPRE-FPS, n=610) completed a questionnaire on lifestyle factors and PA, and underwent PF and body composition measurements at baseline (BL) and over three years of follow-up (3y-FU). PA was categorized according to World Health Organization cut-off PA=0, 0
Source: The British Journal of Nutrition - January 8, 2020 Category: Nutrition Authors: Sjöblom S, Sirola J, Rikkonen T, Erkkilä AT, Kröger H, Qazi SL, Isanejad M Tags: Br J Nutr Source Type: research

Effect of Time Restricted Feeding on Metabolic Risk and Circadian Rhythm Associated with Gut Microbiome in Healthy Males.
Abstract Time restricted feeding (TRF) confer protection against nutritional challenges that predispose obesity and metabolic risks through involvement of clock genes and gut microbiome, but the underline mechanism is not clearly understood. Therefore, this study examined the effects of TRF on metabolic markers and circadian rhythm associated with gut microbiota in healthy males. Two groups (TRF, n=56; Non-TRF, n=24) of male adults were enrolled. TRF group provided blood at Pre-TRF and Post-TRF, while Non-TRF one time after 25 days of trial. Serum lipid and liver profiles were determined. RT-PCR was applied for ci...
Source: The British Journal of Nutrition - January 6, 2020 Category: Nutrition Authors: Zeb F, Wu X, Chen L, Fatima S, Haq IU, Chen A, Majeed F, Feng Q, Li M Tags: Br J Nutr Source Type: research

Acute whole apple consumption did not influence postprandial lipemia: A randomized crossover trial.
This study aimed to explore the effects of whole apple consumption on PPL, as a risk factor for cardiovascular diseases, in generally healthy but overweight and obese adults. A randomized, crossover acute meal trial was conducted with 17 women and 9 men (mean body mass index of 34.1 (SEM 0.2) kg/m2). Blood samples were collected for 6 hours after participants consumed an oral fat tolerance test meal that provided 1 g fat/kg body weight and 1500 mg acetaminophen per meal for estimating gastric emptying, with and without three whole raw Gala apples (~200 g). Plasma triacylglycerol (TAG, with peak postprandial concentration a...
Source: The British Journal of Nutrition - January 6, 2020 Category: Nutrition Authors: Lin X, Liddle DM, Neizer HR, Robinson LE, Wright AJ Tags: Br J Nutr Source Type: research

Body composition in very preterm infants before discharge is associated with macronutrient intake.
Abstract Very preterm infants experience poor postnatal growth relative to intrauterine growth rates but have increased %body fat (%fat). The aim of this study was to identify nutritional and other clinical predictors of infant %fat, fat mass (g) and lean mass (g) in very preterm infants during their hospital stay. Daily intakes of protein, carbohydrate, lipids and energy were recorded from birth to 34weeks postmenstrual age (PMA) in 50 infants born
Source: The British Journal of Nutrition - January 6, 2020 Category: Nutrition Authors: Lingwood BE, Al-Theyab N, Eiby YA, Colditz PB, Donovan TJ Tags: Br J Nutr Source Type: research

The effects of omega-3 fatty acids from flaxseed oil on genetic and metabolic profiles in patients with gestational diabetes mellitus: a randomized, double-blind, placebo-controlled trial.
This study was performed to evaluate the effects of omega-3 fatty acids from flaxseed oil on genetic and metabolic profiles in patients with gestational diabetes mellitus (GDM). This randomized, double-blind, placebo-controlled clinical trial was performed in 60 women with GDM. Participants were randomly divided into two groups to intake either 2 x 1,000 mg/day omega-3 fatty acids from flaxseed oil containing 400 mg α-linolenic acid in each capsule (n=30) or placebo (n=30) for 6 weeks. Omega-3 fatty acids intake upregulated peroxisome proliferator-activated receptor gamma (P
Source: The British Journal of Nutrition - January 6, 2020 Category: Nutrition Authors: Jamilian M, Tabassi Z, Reiner Ž, Panahandeh I, Naderi F, Aghadavood E, Amirani E, Taghizadeh M, Shafabakhsh R, Satari M, Mansournia MA, Memarzadeh MR, Asemi Z Tags: Br J Nutr Source Type: research

Body composition-derived BMI cut-offs for overweight and obesity in ethnic Indian and Creole urban children of Mauritius.
Abstract It is increasingly recognized that the use of body mass index (BMI) cut-off points for diagnosing obesity and proxy measures for body fatness in a given population needs to take into account the potential impact of ethnicity on the BMI-Fat% relationship in order to avoid adiposity status misclassification. This relationship was studied here in 377 Mauritian school children (200 boys and 177 girls, aged 7-13 years) and belonging to the two main ethnic groups: Indian (South Asian descent) and Creole (African/Malagasy descent), with body composition assessed using isotopic deuterium dilution technique as ref...
Source: The British Journal of Nutrition - January 6, 2020 Category: Nutrition Authors: Ramuth H, Hunma S, Ramessur V, Ramuth M, Monnard C, Montani JP, Schutz Y, Joonas N, Dulloo AG Tags: Br J Nutr Source Type: research

The relationship between residential altitude and stunting: evidence from > 26,000 children living in highlands and lowlands of Ethiopia.
The relationship between residential altitude and stunting: evidence from>26,000 children living in highlands and lowlands of Ethiopia. Br J Nutr. 2020 Jan 06;:1-21 Authors: Mohammed SH, Habtewold TD, Abdi DD, Alizadeh S, Larijani B, Esmaillzadeh A Abstract Little information is known about the influence of altitude on child growth in Ethiopia, where most people live at highlands. We investigated the relation of residential altitude with growth faltering (stunting) of infants and young children in Ethiopia. We also examined whether the altitude-growth relationship was independent of the influence o...
Source: The British Journal of Nutrition - January 6, 2020 Category: Nutrition Authors: Mohammed SH, Habtewold TD, Abdi DD, Alizadeh S, Larijani B, Esmaillzadeh A Tags: Br J Nutr Source Type: research

Effects of timing of food intake on eating patterns, diet quality and weight gain during pregnancy.
Abstract Studies have suggested that meal timing plays a role in nutritional health, but this subject has not been sufficiently studied in pregnant women. We analysed the effect that timing of food intake has on eating patterns, diet quality and weight gain in a prospective cohort study with 100 pregnant women. Data were collected once per trimester: 4th to 12th; 20th to 26th; 30th to 37th weeks. Food intake was evaluated using three 24-Hour Dietary Recalls, which was used to assess eating patterns and diet quality. Distribution of energy and macronutrient intake throughout the day was considered eating patterns. ...
Source: The British Journal of Nutrition - January 6, 2020 Category: Nutrition Authors: Gontijo CA, Balieiro LCT, Teixeira GP, Fahmy WM, Crispim CA, Maia YCP Tags: Br J Nutr Source Type: research

Micronutrient-fortified infant cereal improves hemoglobin status and reduces iron deficiency anemia in Indian infants: An effectiveness study.
Abstract Anemia affects ~69% of Indian children aged 6-12 months, with iron deficiency (ID) being a common cause. The effectiveness of micronutrient-fortified infant cereal in improving iron status and neurodevelopment was evaluated in non-anemic and mildly anemic Indian infants. An intervention group (IC) enrolled at age 6 months consumed 50 g/d of rice-based cereal providing 3·75 mg iron/d as ferrous fumarate for 6 months (n 80) and was compared with a matched static cross-sectional control group (CG) without intervention enrolled at age 12 months (n 80). Mean hemoglobin was higher in IC (118·1 g/l...
Source: The British Journal of Nutrition - January 3, 2020 Category: Nutrition Authors: Awasthi S, Reddy NU, Mitra M, Singh S, Ganguly S, Jankovic I, Grathwohl D, Cercamondi CI, Ghosh A Tags: Br J Nutr Source Type: research

The association of dietary glycaemic index and glycaemic load with gestational weight gain and newborn birth weight.
MABL Abstract Diet during pregnancy is related to several maternal and infant health outcomes, however, the relationship between maternal dietary glycaemic index (GI) and glycaemic load (GL) and gestational weight gain (GWG) or newborn birth weight is controversial. The purpose of this study was to investigate the relationship between maternal dietary GI and GL and GWG and birth weight. A cohort of adult pregnant women with usual obstetric risk was followed in Botucatu, SP, Brazil. Two 24-hour dietary recalls were collected in each gestational trimester (
Source: The British Journal of Nutrition - December 23, 2019 Category: Nutrition Authors: Gomes CB, Malta MB, Antunes JLF, Gallo CO, Benício MHD, Carvalhaes MABL Tags: Br J Nutr Source Type: research

Effect of Probiotic Supplementation in Pregnant Women: A Meta-analysis of Randomized Controlled Trials.
Abstract Probiotics are being used increasingly in pregnant women, whereas the efficiency on pregnancy outcomes is yet lacking. The meta-analysis was conducted to investigate the effectiveness of probiotic supplementation in pregnant women based on published randomized controlled trials (RCTs). PubMed, Embase, and the Cochrane library were searched throughout August 2018 to select the RCTs focused on the effectiveness of probiotic supplementation in pregnant women. Relative risks or weighted mean differences with 95% confidence intervals were employed to calculate the summary outcomes. A total of 18 RCTs including...
Source: The British Journal of Nutrition - December 20, 2019 Category: Nutrition Authors: Kuang L, Jiang Y Tags: Br J Nutr Source Type: research

Trans-10, cis-12 conjugated linoleic acid (CLA) reduces milk fat content and lipogenic gene expression in the mammary gland of sows without altering litter performance.
The objective was to evaluate the effect of CLA on milk composition and lipogenic gene expression. Twenty multiparous sows were randomly assigned to one of the two treatments for 18 days (from d 7 through d 25 of lactation): 1) Control (no CLA added) and; 2) 1% of CLA mixed into the ration. CLA treatment decreased milk fat and protein content by 20% (P = 0.004) and 11% (P = 0.0001), respectively. However, piglet weight did not differ between treatments (P = 0.60). Dietary CLA increased the concentration of SFA in milk fat by 16% (P
Source: The British Journal of Nutrition - December 17, 2019 Category: Nutrition Authors: Sandri EC, Harvatine KJ, Oliveira DE Tags: Br J Nutr Source Type: research

Diet quality in late midlife is associated with faster walking speed in later life in women, but not men: findings from a prospective British birth cohort.
Abstract Healthy diet has been linked to better age-related physical functioning, but evidence on the relationship of overall diet quality in late midlife and clinically relevant measures of physical functioning in later life is limited. Research on potential sex differences in this relationship is scarce. The aim was to investigate the prospective association between overall diet quality, as assessed by the Healthy Eating Index-2015 at age 60-64y and measures of walking speed seven years later, among men and women from the Insight46, a neuroscience sub-study of the Medical Research Council National Survey of Heal...
Source: The British Journal of Nutrition - December 16, 2019 Category: Nutrition Authors: Tektonidis TG, Coe S, Esser P, Maddock J, Buchanan S, Mavrommati F, Schott JM, Izadi H, Richards M, Dawes H Tags: Br J Nutr Source Type: research

A simple cut-off for waist-to-height ratio (0.5) can act as an indicator for cardiometabolic risk: recent data from adults in the Health Survey for England.
Abstract The National Institute for Health and Care Excellence (NICE) has acknowledged the value of waist-to-height ratio (WHtR) as an indicator for 'early health risk'. We used recent UK data to explore whether classification based on WHtR identifies more adults at cardiometabolic risk than the 'matrix' based on BMI and waist circumference, currently used for screening. Data from the Health Survey for England (4112 adults aged 18y+) were used to identify cardiometabolic risk, indicated by raised glycated haemoglobin, dyslipidaemia and hypertension. HbA1c, total/HDL cholesterol and SBP were more strongly associate...
Source: The British Journal of Nutrition - December 16, 2019 Category: Nutrition Authors: Gibson S, Ashwell M Tags: Br J Nutr Source Type: research

Whole digesta properties as influenced by feed processing explain variation in gastrointestinal transit times in pigs.
Abstract Physicochemical properties of diets are believed to play a major role in the regulation of digesta transit in the gastrointestinal tract. Starch, being the dominant nutrient in pig diets, strongly influences these properties. We studied transport of digesta solids and liquids through the upper gastrointestinal tract of ninety pigs in a 3 × 3 factorial arrangement. Dietary treatments varied in starch source (barley, maize and high-amylose maize) and form (isolated starch, ground cereal and extruded cereal). Mean retention times (MRT) of digesta solids ranged 129-225 min for the stomach and 86-124 min...
Source: The British Journal of Nutrition - December 1, 2019 Category: Nutrition Authors: Martens BMJ, Noorloos M, de Vries S, Schols HA, Bruininx EMAM, Gerrits WJJ Tags: Br J Nutr Source Type: research

Novel insights for SREBP-1 as a key transcription factor in regulating lipogenesis in a freshwater teleost, grass carp Ctenopharyngodon idella.
Abstract Disturbances in lipid metabolism are at the core of several health issues facing modern society, including fatty liver and obesity. The sterol regulatory element-binding protein 1 (SREBP-1) is one important transcription factor regulating lipid metabolism, but the relevant mechanism still remains unknown. The present study determined the transcriptional regulation of SREBP-1 and its target genes (including acetyl-CoA carboxylase α (accα), fatty acid synthase (fas) and stearoyl-CoA desaturase 1 (scd1)) in a freshwater teleost, grass carp Ctenopharyngodon idella. We cloned and characterised the ...
Source: The British Journal of Nutrition - December 1, 2019 Category: Nutrition Authors: Xu YH, Tan XY, Xu YC, Zhao T, Zhang LH, Luo Z Tags: Br J Nutr Source Type: research

Reproductive state and choline intake influence enrichment of plasma lysophosphatidylcholine-DHA: a post hoc analysis of a controlled feeding trial.
Abstract The major facilitator superfamily domain 2a protein was identified recently as a lysophosphatidylcholine (LPC) symporter with high affinity for LPC species enriched with DHA (LPC-DHA). To test the hypothesis that reproductive state and choline intake influence plasma LPC-DHA, we performed a post hoc analysis of samples available through 10 weeks of a previously conducted feeding study, which provided two doses of choline (480 and 930 mg/d) to non-pregnant (n 21), third-trimester pregnant (n 26), and lactating (n 24) women; all participants consumed 200 mg of supplemental DHA and 22 % o...
Source: The British Journal of Nutrition - December 1, 2019 Category: Nutrition Authors: Klatt KC, McDougall MQ, Malysheva OV, Brenna JT, Roberson MS, Caudill MA Tags: Br J Nutr Source Type: research

Integrated metabolomic and transcriptomic analyses suggest that high dietary lipid levels facilitate ovary development through the enhanced arachidonic acid metabolism, cholesterol biosynthesis and steroid hormone synthesis in Chinese sturgeon (Acipenser sinensis).
In conclusion, 18 % dietary lipid is the optimal level for improving gonad development of female Chinese sturgeon. PMID: 31782378 [PubMed - in process] (Source: The British Journal of Nutrition)
Source: The British Journal of Nutrition - December 1, 2019 Category: Nutrition Authors: Leng X, Zhou H, Tan Q, Du H, Wu J, Liang X, He S, Wei Q Tags: Br J Nutr Source Type: research

A survey of bolus tube feeding prevalence and practice in adult patients requiring home enteral tube feeding.
Abstract Anecdotal evidence suggests the use of bolus tube feeding is increasing in the long-term home enteral tube feed (HETF) patients. A cross-sectional survey to assess the prevalence of bolus tube feeding and to characterise these patients was undertaken. Dietitians from ten centres across the UK collected data on all adult HETF patients on the dietetic caseload receiving bolus tube feeding (n 604, 60 % male, age 58 years). Demographic data, reasons for tube and bolus feeding, tube and equipment types, feeding method and patients' complete tube feeding regimens were recorded. Over a third of patients receivin...
Source: The British Journal of Nutrition - December 1, 2019 Category: Nutrition Authors: Hubbard GP, Andrews S, White S, Simpson G, Topen S, Carnie L, Murphy C, Collins R, Davies J, Owen A, Barker J, Green L, Patel I, Ridgway J, Lenchner J, Faerber J, Pearce L, Meanwell H, Kominek N, Stark L, Best H, Simons R, Cross T, Stratton RJ Tags: Br J Nutr Source Type: research

Post- moderate intensity exercise energy replacement does not reduce subsequent appetite and energy intake in adolescents with obesity.
Abstract Exercise modifies energy intake in adolescents with obesity, but whether this is mediated by the exercise-induced energy deficit remains unknown. The present study examined the effect of exercise with and without dietary replacement of the exercise energy expenditure on appetite, energy intake and food reward in adolescents with obesity. Fourteen 12-15 years adolescents with obesity (8girls; Tanner3-4; BMI 34.8±5.7kg/m2; BMI-z score 2.3±0.4) randomly completed 3 experimental conditions: i) rest control (CON); ii) 30-min cycling (EX); iii) 30-min cycling with dietary energy replacement (EX+R)...
Source: The British Journal of Nutrition - November 29, 2019 Category: Nutrition Authors: Thivel D, Roche J, Miguet M, Fillon A, Khammassi M, Beaulieu K, Finlayson G, Pereira B, Miyashita M, Thackray AE, Masurier J, Duclos M, Boirie Y Tags: Br J Nutr Source Type: research

Dietary protein insufficiency - an important consideration in fatty liver disease?
Abstract Dietary protein insufficiency has been linked to excessive triglyceride storage (TG) and non-alcoholic fatty liver disease (NAFLD) in developing countries. Hepatic TG accumulation following a low-protein diet may be due to altered peroxisomal, mitochondrial and gut microbiota function. Hepatic peroxisomes and mitochondria normally mediate metabolism of nutrients to provide energy and substrates for lipogenesis. Peroxisome biogenesis and activities can be modulated by odd (OCFA) and short-chain (SCFA) fatty acids that are derived from gut bacteria e.g. propionate and butyrate. Also produced during amino ac...
Source: The British Journal of Nutrition - November 29, 2019 Category: Nutrition Authors: Ampong I, Watkins A, Gutierrez-Merino J, Ikwuobe J, Griffiths HR Tags: Br J Nutr Source Type: research

Arginine promotes porcine type I muscle fibers formation through improvement of mitochondrial biogenesis.
This study aimed to investigate whether arginine promotes porcine type I muscle fibers formation via improving mitochondrial biogenesis. In the in vivo study, a total of sixty DLY (Duroc × Landrace × Yorkshire) weaning piglets with an average body weight of 6.55 ± 0.36 kg were randomly divided into four treatments and fed with a basal diet or a basal diet supplemented with 0.5%, 1.0% and 1.5% L-arginine, respectively, in a four-week trial. Results showed that dietary supplementation of 1.0% arginine significantly enhanced the activity of succinate dehydrogenase, upregulated the protein expression of myos...
Source: The British Journal of Nutrition - November 29, 2019 Category: Nutrition Authors: Chen X, Luo X, Chen D, Yu B, He J, Huang Z Tags: Br J Nutr Source Type: research

Association of supplemental calcium and dairy milk intake with all-cause and cause-specific mortality in the UK Biobank: a prospective cohort study.
n E Abstract Excessive calcium intakes have been proposed to associate with vascular calcification and a higher risk of prostate cancer. We investigated the associations of supplemental and dietary calcium intake with mortality using data from 497,828 UK Biobank participants. The average follow-up was 4.2 years and 14,255 participants died, 8,297 from cancer, 2,959 from cardiovascular diseases and 572 from respiratory disease. The use of calcium supplements and milk consumption were associated with differences in mortality in younger (≤65 years) but not in older participants (>65 years, Pinteraction≤0.04 ...
Source: The British Journal of Nutrition - November 29, 2019 Category: Nutrition Authors: Stasinopoulos LC, Zhou A, Hyppönen E Tags: Br J Nutr Source Type: research

Modulation of growth hormone receptor-IGF1 axis by dietary protein in young ruminants.
Abstract A reduced protein intake causes a decrease in insulin-like growth factor 1 (IGF1) concentrations and modulates calcium (Ca) homeostasis in young goats. The IGF1 is synthesised by the liver in response to stimulation by growth hormone (GH). Due to rumino-hepatic circulation of urea, ruminants are suitable for investigating the effects of a protein reduction despite sufficient energy intake. The present study aimed to investigate the impact of a protein reduced diet on the expression of components of the somatotropic axis. Male young goats were divided into two feeding groups receiving either a control diet...
Source: The British Journal of Nutrition - November 28, 2019 Category: Nutrition Authors: Firmenich CS, Schnepel N, Hansen K, Schmicke M, Muscher-Banse AS Tags: Br J Nutr Source Type: research

Amine variations in faecal content in the first weeks of life of newborns in relation to breast-feeding or infant formulas.
ima P, Sánchez M Abstract Breast-feeding is the ideal nutrition for a newborn's integral necessities. It seems crucial therefore to know its composition in order to provide suitable infant formula when required. Of these, polyamines (with lactation and the microbiota being its intestinal source) are involved in the development of gut epithelium and immunity. Safety concerns limit human intervention studies. Therefore, we studied the amounts of polyamines supplied by breast milk (varying among mothers) or infant formula feeding, up to day 30 postpartum, in the faeces of newborns. Independent samples (68) of ...
Source: The British Journal of Nutrition - November 12, 2019 Category: Nutrition Authors: Suárez L, Moreno-Luque M, Martínez-Ardines I, González N, Campo P, Huerta-Cima P, Sánchez M Tags: Br J Nutr Source Type: research

Vitamin A intakes remain higher among intervention participants 3 years after a biofortification intervention in Mozambique.
This study measures the lasting effects of the REU project, 3 years after the project ended, on vitamin A intake. To do so, dietary intake data were collected in the same thirty-six villages as the original study, focusing on both women of child-bearing age and children under 6 years old, the latter including both children who had been measured before and younger children (under 3 years old) in the same farmer groups. The dietary intake is then converted to micronutrient intake to compare treated households with control households. Vitamin A intake remains higher in treated villages than in control villages among both chil...
Source: The British Journal of Nutrition - November 12, 2019 Category: Nutrition Authors: de Brauw A, Moursi M, Munhaua AB Tags: Br J Nutr Source Type: research

Glycaemic, gastrointestinal, hormonal and appetitive responses to pearl millet or oats porridge breakfasts: a randomised, crossover trial in healthy humans.
In conclusion, the present study reports, for the first time, data on glycaemic and physiological responses to a pearl millet breakfast, showing that this ancient grain could represent a sustainable alternative with health-promoting characteristics comparable with oats. GIP is an incretin hormone linked to TAG absorption in adipose tissue; therefore, the lower GIP response for PMP may be an added health benefit. PMID: 31709970 [PubMed - in process] (Source: The British Journal of Nutrition)
Source: The British Journal of Nutrition - November 12, 2019 Category: Nutrition Authors: Alyami J, Whitehouse E, Yakubov GE, Pritchard SE, Hoad CL, Blackshaw E, Heissam K, Cordon SM, Bligh HFJ, Spiller RC, Macdonald IA, Aithal GP, Gowland PA, Taylor MA, Marciani L Tags: Br J Nutr Source Type: research

Konjac glucomannan polysaccharide and inulin oligosaccharide enhance the colonic mucosal barrier function and modulate gut-associated lymphoid tissue immunity in C57BL/6J mice.
In conclusion, supplementation of low-level, 2% (w/w), of KGM and inulin was sufficient to enhance the mucosal barrier function and anti-inflammatory status. PMID: 31699162 [PubMed - as supplied by publisher] (Source: The British Journal of Nutrition)
Source: The British Journal of Nutrition - November 8, 2019 Category: Nutrition Authors: Changchien CH, Han YC, Chen HL Tags: Br J Nutr Source Type: research

Does maternal smoking in pregnancy explain the differences in the body composition trajectory between breastfed and formula-fed infants?
Abstract Growth patterns are known to differ between breastfed and formula-fed infants, but little is known about the relative impact of maternal smoking in pregnancy vs. feeding mode on growth trajectory in infancy. We conducted a secondary analysis of a trial, the TIGGA trial involving 290 healthy infants, to examine whether smoking in pregnancy modified the association between feeding mode and body composition of infants. Fat mass (FM) and fat free mass (FFM) were estimated at 1, 2, 3, 4, 6 and 12 months of age using bioimpedance spectroscopy. Formula-fed infants (n=190) had a higher mean FFM at four months [me...
Source: The British Journal of Nutrition - November 8, 2019 Category: Nutrition Authors: Zhou SJ, Hawke K, Collins CT, Gibson RA, Makrides M Tags: Br J Nutr Source Type: research

Human bioavailability of phenolic compounds found in common beans: the use of high resolution mass spectrometry to evaluate inter individual variability.
Abstract Although common beans (Phaseolus vulgaris L.) are consumed worldwide, studies on the metabolic fate of phenolic compounds from common beans are still very scarce. The present work aimed to study the bioavailability of phenolic compounds in human plasma and urine, after acute consumption of a single meal of cooked common beans. Blood and urine of seven volunteers were collected before (0 h) and at different time points (1, 2, 4, 6 and 8 h, for plasma and 0-2, 2-4, 4-6, 6-8, 8-24 h for urine) after beans' intake. UPLC-Q-TOF-MS was used for quantification. After beans' intake (405 ± 3 g), containing 4...
Source: The British Journal of Nutrition - November 8, 2019 Category: Nutrition Authors: Mecha E, Feliciano RP, Rodriguez-Mateos A, Silva SD, Figueira ME, Vaz Patto MC, Bronze MR Tags: Br J Nutr Source Type: research

The association between dietary energy intake and the risk of mortality in maintenance hemodialysis patients: a multicenter prospective cohort study.
Abstract Maintenance hemodialysis (MHD) is the use of a machine to filter wastes, salts and fluid from blood for at least 3 months to prolong the life of patients with advanced kidney failure. Although low dietary energy intake (DEI) has been observed in MHD patients, few studies have related DEI to the risk of mortality. To explore this relationship, a study included 1039 MHD patients from 8 centers was conducted. DEI was assessed by three 24-hour diet recalls including one dialysis day and two non-dialysis days, and was normalized to ideal body weight (IBW). All-cause mortality and CVD mortality were the primary...
Source: The British Journal of Nutrition - November 8, 2019 Category: Nutrition Authors: Yang Y, Qin X, Li Y, Lei Z, Li Y, Yang S, Li Y, Kong Y, Lu Y, Zhao Y, Wan Q, Wang Q, Huang S, Liu Y, Liu A, Liu F, Hou F, Liang M Tags: Br J Nutr Source Type: research

In vitro prebiotic potential of agricultural by-products on intestinal fermentation, gut barrier and inflammatory status of piglets.
In this study, chicory root and pulp, citrus pulp, rye bran and soy hulls have been tested in a three-step in vitro model of the piglet's gastro-intestinal tract combining a pepsin-pancreatin hydrolysis (digestion), a dialysis step using cellulose membranes (absorption) and a colonic batch fermentation (fermentation). The fermentation kinetics, short-chain fatty acid and microbiota profiles in the fermentation broth were assessed as indicators of prebiotic activity and compared to the ones of inulin. The immunomodulatory effects of fermentation supernatant (FS) were investigated in cultured intestinal porcine epithelial ce...
Source: The British Journal of Nutrition - November 8, 2019 Category: Nutrition Authors: Uerlings J, Schroyen M, Bautil A, Courtin C, Richel A, Sureda EA, Bruggeman G, Tanghe S, Willems E, Bindelle J, Everaert N Tags: Br J Nutr Source Type: research