The Association between Obstructive Sleep Apnea and Venous Thromboembolism: A Bidirectional Two-Sample Mendelian Randomization Study
Conclusion Our bidirectional two-sample MR analysis did not find genetic evidence supporting a significant association between OSA and VTE in either direction.PMID:38631385 | DOI:10.1055/a-2308-2290 (Source: Thrombosis and Haemostasis)
Source: Thrombosis and Haemostasis - April 17, 2024 Category: Hematology Authors: Zhihai Huang Zhenzhen Zheng Lingpin Pang Kaili Fu Junfen Cheng Ming Zhong Lingyue Song Dingyu Guo Qiaoyun Chen Yanxi Li Yongting Lv Riken Chen Xishi Sun Source Type: research
Ticagrelor vs clopidogrel when coadministered with bivalirudin in patients with acute coronary syndrome undergoing percutaneous coronary intervention
CONCLUSION: As an initial treatment strategy, bivalirudin plus ticagrelor could reduce the 12-month risk of ischemic events compared with bivalirudin plus clopidogrel significantly without increasing the bleeding risk in ACS patients undergoing PCI.PMID:38623472 | PMC:PMC11017352 | DOI:10.1016/j.rpth.2024.102375 (Source: Thrombosis and Haemostasis)
Source: Thrombosis and Haemostasis - April 16, 2024 Category: Hematology Authors: Yang Li Yi Li Miaohan Qiu Yu Xue Kai Xu Yaling Han Source Type: research
Tranexamic acid for management of heavy vaginal bleeding: barriers to access and myths surrounding its use
Res Pract Thromb Haemost. 2024 Mar 19;8(3):102389. doi: 10.1016/j.rpth.2024.102389. eCollection 2024 Mar.ABSTRACTTranexamic acid is safe and effective for the treatment of heavy vaginal bleeding during menstruation and childbirth. It improves the quality of life, facilitates participation in school and work, and reduces the risk of death from postpartum hemorrhage. Despite its well-established benefits, individual- and structural-level barriers preclude its widespread utilization, hindering effective patient care and perpetuating health inequities in women's health. We first describe the evidence for the use of tranexamic ...
Source: Thrombosis and Haemostasis - April 16, 2024 Category: Hematology Authors: Heather VanderMeulen Grace H Tang Michelle Sholzberg Source Type: research
Testing for the lupus anticoagulant: the good, the bad, and the ugly
Res Pract Thromb Haemost. 2024 Mar 18;8(3):102385. doi: 10.1016/j.rpth.2024.102385. eCollection 2024 Mar.ABSTRACTLupus anticoagulant (LA) represents 1 of the laboratory criteria for classification of patients as having definite antiphospholipid syndrome (APS). The other 2 laboratory criteria are anticardiolipin antibodies and anti-beta2-glycoprotein I antibodies. At least 1 of these antiphospholipid antibody (aPL) tests need to be positive, with evidence of persistence, together with evidence of at least 1 clinical criterion for APS, before a patient can be classified as having definite APS. LA and other aPL assays are als...
Source: Thrombosis and Haemostasis - April 16, 2024 Category: Hematology Authors: Emmanuel J Favaloro Leonardo Pasalic Rita Selby Source Type: research
Clinical Outcomes of Patients with Atrial Fibrillation who Survived from Bleeding Event: The Results from COOL-AF Thailand Registry
CONCLUSION: Patients with AF who have bleeding events have an increased risk for subsequent death and stroke and systemic embolism. These patients should be identified as vulnerable clinically complex patients and require a holistic approach to their AF management.PMID:38626898 | DOI:10.1055/s-0044-1786028 (Source: Thrombosis and Haemostasis)
Source: Thrombosis and Haemostasis - April 16, 2024 Category: Hematology Authors: Arjbordin Winijkul Pontawee Kaewkumdee Ahthit Yindeengam Gregory Y H Lip Rungroj Krittayaphong Source Type: research
The Role of Clot Waveform Analysis and Related Parameters in the Diagnosis and Treatment of Hemophilia A
CONCLUSION: CWA is an economical and practical tool, and its related parameters are associated with the severity of HA. It has promising clinical prospects in predicting FVIII:C levels and individualized treatment when HA patients undergo replacement therapy.PMID:38626899 | DOI:10.1055/s-0044-1786029 (Source: Thrombosis and Haemostasis)
Source: Thrombosis and Haemostasis - April 16, 2024 Category: Hematology Authors: Guanghao Song Yangbin Wang Lilei Zhang Mao Xia Source Type: research
Practical Suggestions for an Optimal Management of Vitamin K Antagonists: Italian Federation of Centers for the Diagnosis of Thrombotic Disorders and the Surveillance of the Antithrombotic Therapies (FCSA) Position Paper
Thromb Haemost. 2024 Apr 16. doi: 10.1055/s-0044-1782688. Online ahead of print.ABSTRACTIn the era of direct oral anticoagulants, vitamin K antagonists retain a clinically relevant role in thrombotic disorders. In Italy, approximately 20% of the patients on anticoagulant therapies receives a VKA, in most cases warfarin. The optimal management of this drug is challenging and cannot disregard its intricate and unpredictable pharmacokinetic properties and patient's thrombotic and bleeding risk. Several clinical issues encountered during warfarin treatment are still unanswered and are tentatively addressed by physicians. In th...
Source: Thrombosis and Haemostasis - April 16, 2024 Category: Hematology Authors: Silvia Galliazzo Paolo Bucciarelli Doris Barcellona Antonio Ciampa Elvira Grandone Giuseppe Malcangi Giuseppe Rescigno Alessandro Squizzato Vincenzo Toschi Sophie Testa Daniela Poli Source Type: research
Ticagrelor vs clopidogrel when coadministered with bivalirudin in patients with acute coronary syndrome undergoing percutaneous coronary intervention
CONCLUSION: As an initial treatment strategy, bivalirudin plus ticagrelor could reduce the 12-month risk of ischemic events compared with bivalirudin plus clopidogrel significantly without increasing the bleeding risk in ACS patients undergoing PCI.PMID:38623472 | PMC:PMC11017352 | DOI:10.1016/j.rpth.2024.102375 (Source: Thrombosis and Haemostasis)
Source: Thrombosis and Haemostasis - April 16, 2024 Category: Hematology Authors: Yang Li Yi Li Miaohan Qiu Yu Xue Kai Xu Yaling Han Source Type: research
Tranexamic acid for management of heavy vaginal bleeding: barriers to access and myths surrounding its use
Res Pract Thromb Haemost. 2024 Mar 19;8(3):102389. doi: 10.1016/j.rpth.2024.102389. eCollection 2024 Mar.ABSTRACTTranexamic acid is safe and effective for the treatment of heavy vaginal bleeding during menstruation and childbirth. It improves the quality of life, facilitates participation in school and work, and reduces the risk of death from postpartum hemorrhage. Despite its well-established benefits, individual- and structural-level barriers preclude its widespread utilization, hindering effective patient care and perpetuating health inequities in women's health. We first describe the evidence for the use of tranexamic ...
Source: Thrombosis and Haemostasis - April 16, 2024 Category: Hematology Authors: Heather VanderMeulen Grace H Tang Michelle Sholzberg Source Type: research
Testing for the lupus anticoagulant: the good, the bad, and the ugly
Res Pract Thromb Haemost. 2024 Mar 18;8(3):102385. doi: 10.1016/j.rpth.2024.102385. eCollection 2024 Mar.ABSTRACTLupus anticoagulant (LA) represents 1 of the laboratory criteria for classification of patients as having definite antiphospholipid syndrome (APS). The other 2 laboratory criteria are anticardiolipin antibodies and anti-beta2-glycoprotein I antibodies. At least 1 of these antiphospholipid antibody (aPL) tests need to be positive, with evidence of persistence, together with evidence of at least 1 clinical criterion for APS, before a patient can be classified as having definite APS. LA and other aPL assays are als...
Source: Thrombosis and Haemostasis - April 16, 2024 Category: Hematology Authors: Emmanuel J Favaloro Leonardo Pasalic Rita Selby Source Type: research
Can scientific journals benefit from a social media presence? An analysis of online traffic data and author perspectives
Res Pract Thromb Haemost. 2024 Mar 18;8(3):102387. doi: 10.1016/j.rpth.2024.102387. eCollection 2024 Mar.NO ABSTRACTPMID:38617045 | PMC:PMC11015501 | DOI:10.1016/j.rpth.2024.102387 (Source: Thrombosis and Haemostasis)
Source: Thrombosis and Haemostasis - April 15, 2024 Category: Hematology Authors: Mouhamed Yazan Abou-Ismail Dianne E van der Wal May Anne Cheong Andrew Masten Luke Blount Megan C Brown Source Type: research
Venous thromboembolism in pancreatic neuroendocrine neoplasm: a cohort study
Res Pract Thromb Haemost. 2024 Mar 15;8(3):102381. doi: 10.1016/j.rpth.2024.102381. eCollection 2024 Mar.NO ABSTRACTPMID:38617046 | PMC:PMC11015488 | DOI:10.1016/j.rpth.2024.102381 (Source: Thrombosis and Haemostasis)
Source: Thrombosis and Haemostasis - April 15, 2024 Category: Hematology Authors: Lorenzo Gervaso Alice Laffi Aurora Gaeta Sara Gandini Laura Boldrini Monica Isabel Meneses-Medina Manila Rubino Lavinia Benini Michele Borghesani Laura Algeri Giuseppe Curigliano Francesca Spada Chiara Alessandra Cella Nicola Fazio Source Type: research
Mouse tissue factor enzyme-linked immunosorbent assays: a sensitive issue
Res Pract Thromb Haemost. 2024 Mar 18;8(3):102386. doi: 10.1016/j.rpth.2024.102386. eCollection 2024 Mar.NO ABSTRACTPMID:38617047 | PMC:PMC11015504 | DOI:10.1016/j.rpth.2024.102386 (Source: Thrombosis and Haemostasis)
Source: Thrombosis and Haemostasis - April 15, 2024 Category: Hematology Authors: Yotis A Senis Source Type: research
Electrical impedance measurements can identify red blood cell-rich content in acute ischemic stroke clots < em > ex vivo < /em > associated with first-pass successful recanalization
CONCLUSION: Electrical impedance estimations of RBC content in AIS clots are consistent with histologic findings and may have potential for clinically relevant parameters.PMID:38617048 | PMC:PMC11015511 | DOI:10.1016/j.rpth.2024.102373 (Source: Thrombosis and Haemostasis)
Source: Thrombosis and Haemostasis - April 15, 2024 Category: Hematology Authors: Cansu Sahin Alice Giraud Duaa Jabrah Smita Patil Pierluca Messina Franz Bozsak Jean Darcourt Federico Sacchetti Anne-Christine Januel Guillaume Bellanger Jorge Pagola Jesus Juega Hirotoshi Imamura Tsuyoshi Ohta Laurent Spelle Vanessa Chalumeau Uros Mircic Source Type: research
Perioperative management of venous recanalization in a patient with inherited antithrombin deficiency: case report
CONCLUSION: This study describes a successful perioperative management of anticoagulation for venous recanalization that could be suggested to type 1 ATD patients with PTS.PMID:38617049 | PMC:PMC11015152 | DOI:10.1016/j.rpth.2024.102384 (Source: Thrombosis and Haemostasis)
Source: Thrombosis and Haemostasis - April 15, 2024 Category: Hematology Authors: Julie Benzakine Carla Rial Nassim Mohamedi Emmanuel Messas Laetitia Mauge Marc Sapoval Nicolas Gendron Lina Khider Source Type: research
