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Are ibuprofen plus acetaminophen as good as opioids in treating acute extremity pain
3.5 out of 5 stars Effect of a Single Dose of Oral Opioid and Nonopioid Analgesics on Acute Extremity Pain in the Emergency Department: A Randomized Clinical Trial. Chang AK et al. JAMA 2017;318:1661-1667. Abstract As Dr. Demetrios Kyriacou points out in a must-read editorial accompanying this paper, a growing body of evidence clearly indicates that even short-term opioid use for painful injuries or procedures carries a significant risk of leading to chronic use and potential abuse. We are now realizing the importance of avoiding even limited use of drugs such as oxycodone and hydrocodone in opioid-naive patients...
Source: The Poison Review - November 22, 2017 Category: Toxicology Authors: Leon Gussow Tags: Medical acute pain analgesic emergency department opioid Source Type: news

Ibuprofen and acetaminophen combination may be as effective as some opioids for acute extremity pain
According to a study published in the Nov. 7 issue of JAMA, single-dose treatment with ibuprofen and acetaminophen may be as effective as three different opioid and acetaminophen combination analgesics for reducing acute extremity pain in patients who present to the emergency department (ED).  (Source: Orthogate - Latest News)
Source: Orthogate - Latest News - November 11, 2017 Category: Orthopaedics Tags: Featured Editors Choice News Source Type: news

Ibuprofen + Acetaminophen Seems as Effective as Opioids + Acetaminophen for Acute Extremity Pain
Ibuprofen and opioids are similarly effective for short-term relief of acute extremity pain when combined with acetaminophen, according to a JAMA study. Some 400... (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - November 9, 2017 Category: Primary Care Source Type: news

OTC Painkillers Offer Similar Pain Relief as Opioids in ED OTC Painkillers Offer Similar Pain Relief as Opioids in ED
A combination of ibuprofen and acetaminophen was as effective as opioid-acetaminophen combinations in patients presenting to the emergency department with acute extremity pain in a randomized trial.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 8, 2017 Category: Consumer Health News Tags: Emergency Medicine News Source Type: news

Over-The-Counter Pain Relievers Worked As Well As Opioids In New Study
CHICAGO (AP) — Emergency rooms are where many patients are first introduced to powerful opioid painkillers, but what if doctors offered over-the-counter pills instead? A new study tested that approach on patients with broken bones and sprains and found pain relievers sold as Tylenol and Motrin worked as well as opioids at reducing severe pain. The results challenge common ER practice for treating short-term, severe pain and could prompt changes that would help prevent new patients from becoming addicted. The study has limitations: It only looked at short-term pain relief in the emergency room and researchers didn&rsq...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - November 7, 2017 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health Local News Confronting The Crisis opioid crisis Source Type: news

Prenatal exposure to acetaminophen and risk of ADHD - Ystrom E, Gustavson K, Brandlistuen RE, Knudsen GP, Magnus P, Susser E, Davey Smith G, Stoltenberg C, Sur én P, Håberg SE, Hornig M, Lipkin WI, Nordeng H, Reichborn-Kjennerud T.
OBJECTIVES: To estimate the association between maternal use of acetaminophen during pregnancy and of paternal use before pregnancy with attention-deficit/hyperactivity disorder (ADHD) in offspring while adjusting for familial risk for ADHD and indications... (Source: SafetyLit)
Source: SafetyLit - November 6, 2017 Category: International Medicine & Public Health Tags: Age: Infants and Children Source Type: news

Medical News Today: Acetaminophen during pregnancy is associated with ADHD
Acetaminophen use by pregnant women has previously been linked with ADHD in the offspring. A new study backs up these concerning findings. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 3, 2017 Category: Consumer Health News Tags: ADHD / ADD Source Type: news

An association between prenatal acetaminophen use and ADHD: the benefits of large data sets - Wolraich ML.
[Abstract unavailable] Language: en... (Source: SafetyLit)
Source: SafetyLit - November 2, 2017 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

Acetaminophen use in pregnancy linked to ADHD in study, but no cause is proven
Experts question new study linking long-term prenatal use with ADHD in the kids. (Source: ABC News: Health)
Source: ABC News: Health - October 31, 2017 Category: Consumer Health News Tags: Health Source Type: news

Lortab Elixir (Hydrocodone Bitartrate and Acetaminophen Oral Solution) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - October 31, 2017 Category: Drugs & Pharmacology Source Type: news

Lortab 2.5 (Hydrocodone Bitartrate and Acetaminophen Tablets) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - October 31, 2017 Category: Drugs & Pharmacology Source Type: news

Acetaminophen in Pregnancy Linked to ADHD in Kids
Maternal Use of Acetaminophen Linked to ADHD in Kids (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - October 31, 2017 Category: General Medicine Source Type: news

HealthWatch: Colonoscopies, Carbs, And A Link Between Tylenol And ADHD
BOSTON (CBS) — It’s generally recommended that people get their first colonoscopy at age 50, but after analyzing data on 6,000 procedures, French researchers say starting screening at age 45 could save lives. U.S. experts say there were some flaws with this study, so right now the American Cancer Society is standing by its recommendations to start screening at age 50 for people at average risk of developing colon cancer. If, however, you have a family history of colon cancer, you may need to be screened sooner. Does Tylenol Increase the Risk of ADHD in Offspring? Researchers in Norway found that pregnant moms w...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - October 30, 2017 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health Healthwatch Local News Seen On WBZ-TV Syndicated Local Dr. Mallika Marshall Source Type: news

Pain drugs in pregnancy tied to ADHD
(Reuters Health) - Women who use a lot of the common pain reliever acetaminophen during pregnancy may be more likely to have children with attention deficit hyperactivity disorder (ADHD) than those who don ’t use the drug, a Norwegian study suggests. (Source: Reuters: Health)
Source: Reuters: Health - October 30, 2017 Category: Consumer Health News Tags: healthNews Source Type: news

Maternal Use of Acetaminophen Linked to ADHD in Offspring
Link seen after adjustment for maternal use before pregnancy, familial risk for ADHD (Source: The Doctors Lounge - Psychiatry)
Source: The Doctors Lounge - Psychiatry - October 30, 2017 Category: Psychiatry Tags: Family Medicine, Gynecology, Infections, Neurology, Nursing, Pathology, Pediatrics, Pharmacy, Psychiatry, Rheumatology, Anesthesiology & amp; Pain, Journal, Source Type: news

Maternal Use of Acetaminophen Linked to ADHD in Kids Maternal Use of Acetaminophen Linked to ADHD in Kids
The risk is related to duration of use, but the causal relationship is still questionable, authors caution.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - October 30, 2017 Category: Consumer Health News Tags: Pediatrics News Source Type: news

Acetaminophen during pregnancy tied to ADHD risk in kids
A new study adds to evidence linking extended use of the medication to an increased risk of behavioral issues in children (Source: Health News: CBSNews.com)
Source: Health News: CBSNews.com - October 30, 2017 Category: Consumer Health News Source Type: news

Acetaminophen in Pregnancy Tied to ADHD Risk
Acetaminophen is considered the go-to pain medication during pregnancy. But a new study adds to evidence linking the drug to an increased risk of behavioral issues in kids. (Source: WebMD Health)
Source: WebMD Health - October 30, 2017 Category: Consumer Health News Source Type: news

Acetaminophen in Pregnancy Tied to ADHD Risk in Kids
Source: HealthDay Related MedlinePlus Pages: Attention Deficit Hyperactivity Disorder, Pregnancy and Medicines (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - October 30, 2017 Category: Consumer Health News Source Type: news

An Asian-American adolescent with a suicide attempt - Nissirios KS, Levitt WG, Pimentel J.
A 15-year-old Asian-American girl who was enrolled in high school and lived with her parents and two older sisters attempted suicide by ingesting 25 tablets of acetaminophen (each of which were 325 mg). The patient reported that her stress was triggered by... (Source: SafetyLit)
Source: SafetyLit - October 30, 2017 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

Acetaminophen in Pregnancy Tied to ADHD Risk in Kids
MONDAY, Oct. 30, 2017 -- Acetaminophen is considered the go-to pain medication during pregnancy. But a new study adds to evidence linking the drug to an increased risk of behavioral issues in kids. Researchers in Norway found that among nearly... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - October 30, 2017 Category: General Medicine Source Type: news

Study links acetaminophen in pregnancy to ADHD
Long-term use of acetaminophen during pregnancy was associated with twice the risk of attention-deficit hyperactivity disorder in children, according to a study published Monday in the journal Pediatrics. However, two experts believe that the data do not support these findings. (Source: CNN.com - Health)
Source: CNN.com - Health - October 30, 2017 Category: Consumer Health News Source Type: news

Long-Term Acetaminophen Use in Pregnancy Tied to ADHD in Offspring (FREE)
By Amy Orciari Herman Edited by Susan Sadoughi, MD, and Andr é Sofair, MD, MPH Long-term use of acetaminophen during pregnancy is associated with increased risk for attention-deficit/hyperactivity disorder in offspring, a Pediatrics study suggests. The researchers caution, however, that their data can't prove … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - October 30, 2017 Category: Primary Care Source Type: news

What is Usher Syndrome?
Discussion Over 7000 diseases are considered rare disorders according to the National Organization for Rare Disorders® (NORD, rarediseases.org). NORD is a patient advocacy organization dedicated to individuals with rare diseases and the organizations that serve them. They have information on about 1200 rare diseases on their website (https://rarediseases.org/for-patients-and-families/information-resources/rare-disease-information/). Hearing loss (HL) is not rare and is a common problem across the ages. It affects 360 million people worldwide which is about 5% of the population. There are many causes of hearing loss an...
Source: PediatricEducation.org - October 23, 2017 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Easy Fix for Post-Op Shivers?
SATURDAY, Oct. 21, 2017 -- Giving patients acetaminophen during surgery may reduce their risk of shivering when they wake up, according to a small study. Up to half of patients have shivers and chills when they regain consciousness after surgery.... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - October 21, 2017 Category: General Medicine Source Type: news

Acetaminophen may help reduce postoperative shivering
(American Society of Anesthesiologists) Administering acetaminophen, such as Tylenol, during surgery may reduce the incidence of postoperative shivering, suggests a study being presented at the ANESTHESIOLOGY ® 2017 annual meeting. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 21, 2017 Category: International Medicine & Public Health Source Type: news

Darvocet-N (Propoxyphene Napsylate and Acetaminophen) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - October 12, 2017 Category: Drugs & Pharmacology Source Type: news

Fever in pregnancy causes heart, facial birth defects
Fever in early pregnancy can lead to heart and facial defects in a fetus, a new study from Duke University reveals. Researchers say that taking acetaminophen may prevent defects. (Source: the Mail online | Health)
Source: the Mail online | Health - October 10, 2017 Category: Consumer Health News Source Type: news

Lupin launches pain relieving generic tablets in US
Lupin's product is a generic version of Allergan Sales LLC's Norco tablets in the same strengths and is indicated for relief of moderate to moderately severe pain. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - October 10, 2017 Category: Pharmaceuticals Source Type: news

Surgery Can Be Trigger for Teen Opioid Abuse
FRIDAY, Sept. 15, 2017 -- Teens and young adults who have surgery may be at increased risk for opioid painkiller abuse, a new study indicates. Opioids such as oxycodone (OxyContin) and hydrocodone (Vicodin) are commonly prescribed for pain after... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - September 15, 2017 Category: General Medicine Source Type: news

Codeine vs. Vicodin
Title: Codeine vs. VicodinCategory: MedicationsCreated: 9/13/2017 12:00:00 AMLast Editorial Review: 9/13/2017 12:00:00 AM (Source: MedicineNet Medications General)
Source: MedicineNet Medications General - September 13, 2017 Category: Drugs & Pharmacology Source Type: news

Psychosocial and behavioral factors in acetaminophen-related acute liver failure and liver injury - Pezzia C, Sanders C, Welch S, Bowling A, Lee WM.
OBJECTIVES: Acetaminophen overdoses result in nearly 500 deaths annually and a much larger number of hospitalizations. Suicidal overdoses are exceeded in number in the United States by unintentional overdoses. We evaluated clinical, demographic and psychos... (Source: SafetyLit)
Source: SafetyLit - September 7, 2017 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Increased acetaminophen related calls to Finnish PIC better reflect acetaminophen sales than serious poisonings - Parry MJ, Isoniemi H, Koivusalo AM, Hoppu K.
OBJECTIVE: Acetaminophen (APAP) or paracetamol is a commonly encountered medicine in poisonings. We studied the changes in APAP related calls to the Finnish poison information centre (FPIC), and serious intoxications, involving hepatotoxicity or death in 2... (Source: SafetyLit)
Source: SafetyLit - August 25, 2017 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Orbivan (Butalbital, Acetaminophen, and Caffeine Capsules, USP) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - August 24, 2017 Category: Drugs & Pharmacology Source Type: news

Hospitals Not to Blame for Most Opioid Addiction: Study
WEDNESDAY, Aug. 16, 2017 -- Painkiller prescriptions that lead to prolonged opioid use tend to be written by doctors in outpatient settings, not hospitals, new research indicates. Initial use of opioids such as OxyContin (oxycodone) and Vicodin... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - August 16, 2017 Category: General Medicine Source Type: news

What Are the Side Effects of Acetaminophen?
Title: What Are the Side Effects of Acetaminophen?Category: Doctor's& Expert's views on SymptomsCreated: 8/4/2017 12:00:00 AMLast Editorial Review: 8/4/2017 12:00:00 AM (Source: MedicineNet Migraine General)
Source: MedicineNet Migraine General - August 4, 2017 Category: Neurology Source Type: news

FDA Drug Safety Communication: Addition of another concentration of liquid acetaminophen marketed for infants
(Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - August 3, 2017 Category: Drugs & Pharmacology Source Type: news

Study: Nearly Half Of People Who Use Cannabidiol Products Stop Taking Traditional Medicines
Forty-two percent of surveyed CBD users said they had stopped using traditional medications like Tylenol pain relievers or prescription drugs like Vicodin and had switched to using cannabis instead. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - August 2, 2017 Category: Pharmaceuticals Authors: Debra Borchardt, Contributor Source Type: news

Survey: Nearly Half Of People Who Use Cannabidiol Products Stop Taking Traditional Medicines
Forty-two percent of surveyed CBD users said they had stopped using traditional medications like Tylenol pain relievers or prescription drugs like Vicodin and had switched to using cannabis instead. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - August 2, 2017 Category: Pharmaceuticals Authors: Debra Borchardt, Contributor Source Type: news

Do Diuretics Interact with Vicodin?
Title: Do Diuretics Interact with Vicodin?Category: Doctor's& Expert's views on SymptomsCreated: 8/2/2017 12:00:00 AMLast Editorial Review: 8/2/2017 12:00:00 AM (Source: MedicineNet Medications General)
Source: MedicineNet Medications General - August 2, 2017 Category: Drugs & Pharmacology Source Type: news

Comprehensive Initiative Has Positive Impact on Opioid Rx
Reductions in all tracked outcomes, including 95 % drop in brand name opioid - acetaminophen products (Source: The Doctors Lounge - Psychiatry)
Source: The Doctors Lounge - Psychiatry - August 1, 2017 Category: Psychiatry Tags: Family Medicine, Geriatrics, Gynecology, Internal Medicine, Emergency Medicine, Neurology, Nursing, Orthopedics, Pharmacy, Psychiatry, Rheumatology, Surgery, Anesthesiology & Pain, Journal, Source Type: news

Policy Changes Reduced Use of Certain Prescription Opioids: Study
TUESDAY, Aug. 1, 2017 -- Tighter U.S. government restrictions on prescription painkillers containing hydrocodone led to reduced use of opioid medications such as Vicodin, a new study says. Between 2007 and 2014, more prescriptions were written in... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - August 1, 2017 Category: General Medicine Source Type: news

Potential acetaminophen and opioid overdoses in young children prescribed combination acetaminophen/opioid preparations - Basco WTJ, Garner SS, Ebeling M, Hulsey TC, Simpson K.
INTRODUCTION: Combination preparations of acetaminophen/opioid are the most common opioid form prescribed to children. We tested the hypothesis that dispensed prescriptions of acetaminophen/opioid preparations more appropriately match acetaminophen dosing ... (Source: SafetyLit)
Source: SafetyLit - July 31, 2017 Category: International Medicine & Public Health Tags: Age: Infants and Children Source Type: news

Public health: acetaminophen (APAP) hepatotoxicity- isn't it time for APAP to go away? - Lee WM.
Acetaminophen (APAP) is the most commonly used drug for the treatment of pain and fever around the world. At the same time, APAP is capable of causing dose-related hepatocellular necrosis, responsible for nearly 500 deaths annually in the U.S. alone, as we... (Source: SafetyLit)
Source: SafetyLit - July 26, 2017 Category: International Medicine & Public Health Tags: Commentary Source Type: news

acetaminophen (Tylenol, Tylenol Arthritis Pain, Tylenol Ext, Little Fevers Children's Fever/Pain)
Title: acetaminophen (Tylenol, Tylenol Arthritis Pain, Tylenol Ext, Little Fevers Children's Fever/Pain)Category: MedicationsCreated: 12/31/1997 12:00:00 AMLast Editorial Review: 7/20/2017 12:00:00 AM (Source: MedicineNet Chronic Pain General)
Source: MedicineNet Chronic Pain General - July 20, 2017 Category: Anesthesiology Source Type: news

When Can a Doctor Help Your Back Pain?
Treatment TermsBack pain TagsBack pain Sub-Title Answers to Common Back Pain Questions Overview More than eight in 10 people will experience back pain at some point in their lives. In most cases, the pain goes away over time. If your back pain is severe or does not improve, you may need medical care. Here are answers to some common questions about back pain and tips on when to seek help. Content Blocks Header Why Does My Back Hurt? ContentThere are various reasons why your back can hurt, including muscle pain, disc pain, joint pain, or nerve pain. In most cases, these are not harmful or dangerous. “There are...
Source: dukehealth.org: Duke Health News - June 28, 2017 Category: Consumer Health News Authors: mf205 at duke.edu Source Type: news

Tramadol with or without paracetamol (acetaminophen) for cancer pain
This Cochrane Review finds very low quality data suggesting tramadol produced pain relief in some adults with pain due to cancer and is not as effective as morphine. There is no evidence for children. The place of tramadol in managing cancer pain and its role as step 2 of the WHO analgesic ladder is unclear. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - June 28, 2017 Category: Consumer Health News Source Type: news

Opioid Crisis: Analgesic Mechanisms of Mu Opiate Drugs (Heroin, Vicodin, Morphine)
U.S. Department of Justice. 04/18/2017 This 31-minute video is a presentation from the National Rx Drug Abuse and Heroin Summit, held on April 17-20, 2017. The speaker provides background and understanding of the opioid crisis, and the increase in opioid use, overdoses, and deaths. She also describes the National Institutes of Health Opioid Research Initiative. (Video or Multimedia) (Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health)
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - June 26, 2017 Category: International Medicine & Public Health Authors: The U.S. National Library of Medicine Source Type: news

Does paracetamol taken in pregnancy affect masculinity?
Conclusion Headlines like those in the media about this study are likely to alarm pregnant women who have taken or may need to take paracetamol in pregnancy. While the study's results can't be dismissed altogether, there are three important things to bear in mind: Studies in mice don't always translate into results in humans. The doses of paracetamol that produced the effects in mice were the equivalent of three times higher than the maximum daily dose for adult humans. The pregnant mice were fed paracetamol every day throughout the last two-thirds of their pregnancy. Most pregnant women take paracetamol at the re...
Source: NHS News Feed - June 23, 2017 Category: Consumer Health News Tags: Pregnancy/child Medication Source Type: news