Severe drug interactions in acetaminophen poisoning in Brazil: a cross- sectional study based on the Notifiable Diseases Information System - Lagemann LM, Okuyama JH, Silva MT.
OBJECTIVE: To describe poisoning by acetaminophen combined with other drugs and to analyze factors associated with severe drug interactions. METHODS: Cases of poisoning involving acetaminophen available in the 2017 Notifiable Diseases Information S... (Source: SafetyLit)
Source: SafetyLit - August 16, 2022 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
Vicodin (Hydrocodone and Acetaminophen) - updated on RxList
Vicodin is a prescription opioid medication used to treat the symptoms of moderate to severe pain. Learn about uses, dosage, side effects, drug interactions, warnings, overdose, and more. (Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - August 9, 2022 Category: Drugs & Pharmacology Source Type: news
He shot my arm off': Armed man flees when 80-year-old store owner fires shotgun, video shows
Surveillance video captured the moment the business owner opened fire on would-be robbers armed with long rifles at the store in Norco, California. #ownerfiresshotgun #norco #businessowner #robbers #rifles #surveillancevideo (Source: Reuters: Health)
Source: Reuters: Health - August 3, 2022 Category: Consumer Health News Source Type: news
What It Really Feels Like to Have Monkeypox
Since the global monkeypox outbreak began in May 2022, more than 22,000 cases have been confirmed in countries around the world. More than 5,000 of those cases have been recorded in the U.S., with many clustered in hotspots including New York and California. The virus, which often results in a blister-like rash and spreads through close contact, has so far predominantly affected men who have sex with men.
Even as cases tick up and monkeypox gains public attention, however, it can still be difficult to find information about testing, treatment, and vaccines. Many people who fear they are at risk or infected are left to seek...
Source: TIME: Health - August 1, 2022 Category: Consumer Health News Authors: Jamie Ducharme, Angela Haupt and Jeffrey Kluger Tags: Uncategorized healthscienceclimate monkeypox Source Type: news
Hong Kong Had the World ’ s Highest COVID-19 Death Rate. It May Not Be Ready for Another Surge
Wong Wing-yan has taken to closing the doors of the empty bedrooms at the suburban Hong Kong nursing home where she works, so she doesn’t have to think about the residents who once occupied them. Some of the rooms are now being used as haphazard storage closets, stacked with mothballed furniture, wheelchairs, and boxes of personal protective equipment (PPE). Marks left by tape can still be seen on the walls, where photos of loved ones were once displayed.
“There are many empty rooms now,” said Wong, a bespectacled nurse in her thirties, as she walked TIME through the facility in late April. “I’...
Source: TIME: Health - July 28, 2022 Category: Consumer Health News Authors: Vanesse Chan/Hong Kong and Amy Gunia/Hong Kong Tags: Uncategorized COVID-19 feature Hong Kong Londontime overnight Source Type: news
Acetaminophen Blunts Antitumor Activity of Immunotherapy
(MedPage Today) -- Patients starting cancer immunotherapy with detectable levels of acetaminophen had worse outcomes, including response rate, progression-free survival (PFS), and overall survival (OS), in data from three patient cohorts.
In the... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - July 7, 2022 Category: Hematology Source Type: news
Coordinated activation of TGF- β and BMP pathways promotes autophagy and limits liver injury after acetaminophen intoxication
TGF- β and BMP signaling promote autophagy after acetaminophen-induced liver injury. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - June 28, 2022 Category: Science Source Type: news
Janssen Presents Updated Data at EHA for Teclistamab in Patients with Relapsed or Refractory Multiple Myeloma
June 10, 2022 (VIENNA) – The Janssen Pharmaceutical Companies of Johnson & Johnson announced updated efficacy and safety results from the teclistamab cohort of the Phase 1b TriMM-2 study (NCT04108195). Teclistamab, an investigational, off-the-shelf, T-cell redirecting bispecific antibody targeting B-cell maturation antigen (BCMA) is being studied in combination with DARZALEX FASPRO® (daratumumab and hyaluronidase-fihj) in patients with relapsed or refractory multiple myeloma (RRMM) who have received three or more prior lines of therapy.1 Patients in the study, including a high proportion with prior anti-CD38 exposur...
Source: Johnson and Johnson - June 10, 2022 Category: Pharmaceuticals Tags: Innovation Source Type: news
Janssen Presents Updated Results Evaluating First-in-Class GPRC5D Bispecific Antibody Talquetamab in Heavily Pretreated Patients with Multiple Myeloma
June 10, 2022 (VIENNA) – The Janssen Pharmaceutical Companies of Johnson & Johnson announced updated results from the Phase 1 MonumenTAL-1 first-in-human dose-escalation study of talquetamab (NCT03399799), an investigational, off-the-shelf, T cell redirecting bispecific antibody targeting both GPRC5D, a novel multiple myeloma target, and CD3 on T cells.1 Results from the study showed encouraging responses in heavily pretreated patients with relapsed or refractory multiple myeloma (RRMM) who received talquetamab at the recommended subcutaneous Phase 2 dose (RP2D) administered weekly (QW) or every two weeks (Q2W).2 The...
Source: Johnson and Johnson - June 10, 2022 Category: Pharmaceuticals Tags: Innovation Source Type: news
Acetaminophen Linked to Diminished Response to Immunotherapy in Cancer Acetaminophen Linked to Diminished Response to Immunotherapy in Cancer
The commonly used pain killer was strongly associated with a diminished response to immune checkpoint inhibitors in a study of 600 patients with cancer.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - June 8, 2022 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news
The Sodium Hidden in Medication: A Tough Pill To Swallow The Sodium Hidden in Medication: A Tough Pill To Swallow
A new study discovered alarming quantities of sodium in some acetaminophen preparations. Should mandatory labeling of medications containing significant quantities of sodium be required?European Heart Journal (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - June 7, 2022 Category: Consumer Health News Tags: Cardiology Journal Article Source Type: news
Updated Data for Janssen ’s Bispecific Teclistamab Suggest Continued Deep and Durable Responses in the Treatment of Patients with Relapsed or Refractory Multiple Myeloma
CHICAGO, ILLINOIS, June 5, 2022 – The Janssen Pharmaceutical Companies of Johnson & Johnson announced updated efficacy and safety results from the teclistamab Phase 1/2 MajesTEC-1 study. Teclistamab is an investigational, off-the-shelf, T-cell redirecting bispecific antibody targeting B-cell maturation antigen (BCMA), which is being studied in patients with relapsed or refractory multiple myeloma (RRMM) who have received three or more prior lines of therapy.1 The data were featured as part of an oral session during the 2022 American Society of Clinical Oncology (ASCO) Annual Meeting. Additional poster presentations f...
Source: Johnson and Johnson - June 5, 2022 Category: Pharmaceuticals Tags: Innovation Source Type: news
A Growing Number of Young People Are Attempting Suicide by Self-Poisoning
Suicides among young people have been on the rise for a long time. Among 10 to 24 year olds, overall rates of deaths by suicide in the U.S. increased 57% from 2000 to 2018, according to federal data. Now, a new study published in the journal Clinical Toxicology has looked more closely at a particular method of attempted suicide—self-poisoning—and turned up some disturbing results: From 2015 to 2020, suicide attempts by ingesting toxic substances or overdosing on medications soared by 26% among people ages 6 to 19.
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The research, led by Dr. Jennifer Ross, a medical tox...
Source: TIME: Health - June 1, 2022 Category: Consumer Health News Authors: Jeffrey Kluger Tags: Uncategorized healthscienceclimate Mental Health Source Type: news
Janssen to Highlight Science, Innovation and Advances in Robust Oncology Portfolio and Pipeline Through More Than 60 Data Presentations at ASCO and EHA
RARITAN, N.J., May 31, 2022 — The Janssen Pharmaceutical Companies of Johnson & Johnson announced today that new research and data from its robust oncology portfolio and pipeline of investigational therapies will be presented at the 2022 American Society of Clinical Oncology (ASCO) Annual Meeting, taking place June 3-7 in Chicago, and the European Hematology Association (EHA) 2022 Congress taking place in Vienna, Austria, June 9-12. More than 60 presentations from company-sponsored studies across the two congresses, including 14 oral presentations, will feature new data and updates for both approved and investigation...
Source: Johnson and Johnson - May 31, 2022 Category: Pharmaceuticals Source Type: news
$3.2M Grant Brings UAMS Overdose Test Closer to Market
The money will fund a final study of the acetaminophen toxicity test before researchers seek FDA approval. (Source: Arkansas Business - Health Care)
Source: Arkansas Business - Health Care - May 23, 2022 Category: American Health Source Type: news
