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Increased risk of congestive heart failure in patients with acetaminophen poisoning: a nationwide cohort study - Chung WS, Lin CL.
Acetaminophen poisoning increases cytochrome P450 2E1 expression and reactive oxygen species production, which may lead to maladaptive myocardial remodeling and congestive heart failure (CHF). We conducted a nationwide cohort study to investigate the incid... (Source: SafetyLit)
Source: SafetyLit - January 16, 2018 Category: International Medicine & Public Health Tags: Home and Consumer Product Safety Source Type: news

What Treatment is Recommended for Common Headaches?
Discussion Headache is pain in the scalp, forehead, orbits and temple. Facial and neck pain are usually excluded from this definition. It is a common problem with more than 6 million pediatric patients having migraine. Headaches can also have co-morbidities and more than 1 primary headache type can co-exist. The costs are high both economically and in the quality of life for the patients and families. A review of common headache types and indications for neuroimaging can be found here. Treatment is necessarily multi-pronged. Patients should understand their diagnosis so they can understand what reasonably can be expected...
Source: PediatricEducation.org - January 15, 2018 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Long-term mortality of acetaminophen poisoning: a nationwide population-based cohort study with 10-year follow-up in Taiwan - Huang HS, Ho CH, Weng SF, Hsu CC, Wang JJ, Su SB, Lin HJ, Huang CC.
BACKGROUND: The long-term mortality of acetaminophen (APAP) poisoning has not yet been well studied; hence, we conducted this study to gain understanding of this issue. METHODS: We conducted a nationwide population-based cohort study by identifying... (Source: SafetyLit)
Source: SafetyLit - January 12, 2018 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Acetaminophen Use in Pregnancy Linked to Language Delay
Number of APAP tablets, urinary APAP concentration linked to increased odds of language delay in girls (Source: The Doctors Lounge - Psychiatry)
Source: The Doctors Lounge - Psychiatry - January 11, 2018 Category: Psychiatry Tags: Family Medicine, Gynecology, Nursing, Pathology, Pediatrics, Pharmacy, Psychiatry, Anesthesiology & amp; Pain, Journal, Source Type: news

Medical News Today: Is acetaminophen really safe in pregnancy?
More than two thirds of pregnant women take acetaminophen at some stage during their pregnancy. New research supports claims that this may be harmful. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - January 11, 2018 Category: Consumer Health News Tags: Pregnancy / Obstetrics Source Type: news

Prenatal Acetaminophen Exposure and Language Delay in Girls Prenatal Acetaminophen Exposure and Language Delay in Girls
Exposure to acetaminophen in utero was more likely to be associated with language delay in girls than in boys.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - January 10, 2018 Category: Consumer Health News Tags: Ob/Gyn & Women ' s Health News Source Type: news

Go-to pregnancy pain-relieving drug delays babies' speech
Researchers from  Mount Sinai hospital in New York found women who take acetaminophen over six times during their early pregnancies are more likely to have daughters with limited vocabularies. (Source: the Mail online | Health)
Source: the Mail online | Health - January 10, 2018 Category: Consumer Health News Source Type: news

Acetaminophen in Pregnancy Tied to Language Delays -- in Baby Girls
WEDNESDAY, Jan. 10, 2018 -- Toddlers whose mothers used acetaminophen -- best known as Tylenol -- early in pregnancy may have a heightened risk of language delays, a new study suggests. Researchers found that when moms-to-be used the painkiller... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - January 10, 2018 Category: General Medicine Source Type: news

Acetaminophen use during pregnancy associated with elevated rate of language delay in girls
(The Mount Sinai Hospital / Mount Sinai School of Medicine) In the first study of its kind, researchers from the Icahn School of Medicine at Mount Sinai found an elevated rate of language delay in girls at 30 months old born to mothers who used acetaminophen during pregnancy, but not in boys. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - January 10, 2018 Category: International Medicine & Public Health Source Type: news

Prenatal Exposure to Acetaminophen Tied to Impaired Fertility in Female Offspring — in Rodents
Patients may ask about a study suggesting that acetaminophen use during pregnancy could have detrimental effects on the reproductive health of female offspring. The findings... (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - January 8, 2018 Category: Primary Care Source Type: news

Acetaminophen poisoning may increase coronary artery disease risk: a nationwide cohort study - Chung YT, Chou CY, Tsai WC, Chen WK, Lin CL, Chung WS.
The purpose of this nationwide cohort study was to investigate the incidence and risk of coronary artery disease (CAD) in patients with acetaminophen (APAP) poisoning. We identified the patients with APAP poisoning and randomly selected comparison patients... (Source: SafetyLit)
Source: SafetyLit - January 7, 2018 Category: International Medicine & Public Health Tags: Home and Consumer Product Safety Source Type: news

Is there a better way to administer IV N-acetylcysteine?
3 out of 5 stars Fewer adverse effects with a modified two-bag acetylcysteine protocol in paracetamol overdose. McNulty R et al. Clin Toxicol 2017 Dec 8 [Epub ahead of print] Abstract Current recommendations for dosing intravenous N-acetylcysteine (Acetadote) for treating acute acetaminophen (paracetamol) poisoning involves a somewhat complex three-bag protocol, using 3 direct concentrations of the antidote given over a 21-hour period. Unfortunately, this protocol results in a high incidence of (usually mild) adverse events, including cutaneous effects, nausea and vomiting, and anaphylactoid reactions. Severe rea...
Source: The Poison Review - December 14, 2017 Category: Toxicology Authors: Leon Gussow Tags: Medical Acetadote acetaminophen antidote N-acetylcysteine paracetamol three-bag protocol toxicity two-bag protocol Source Type: news

Pediatric poisonings: the risk of over-the-counter pharmaceuticals - Hines EQ.
Every week in the United States, 56% of children younger than age 18 years and 82% of adults take at least one medication. Nonprescription medications, including acetaminophen and ibuprofen, are among the most commonly used pharmaceuticals across all age g... (Source: SafetyLit)
Source: SafetyLit - December 14, 2017 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

The Way Over-The-Counter Drugs Are Regulated Is A Mess — And Congress Is Ready To Step In
By Erin Mershon WASHINGTON — The Food and Drug Administration has, for years, limited the amount of acetaminophen in any (Source: Healthy Living - The Huffington Post)
Source: Healthy Living - The Huffington Post - December 11, 2017 Category: Consumer Health News Source Type: news

Acetaminophen vs. Ibuprofen for Pain (Differences between Side Effects adn Dosage)
Title: Acetaminophen vs. Ibuprofen for Pain (Differences between Side Effects adn Dosage)Category: MedicationsCreated: 12/11/2017 12:00:00 AMLast Editorial Review: 12/11/2017 12:00:00 AM (Source: MedicineNet Chronic Pain General)
Source: MedicineNet Chronic Pain General - December 11, 2017 Category: Anesthesiology Source Type: news

Acetaminophen-induced acute liver failure is more common and more severe in women - Rubin JB, Hameed B, Gottfried M, Lee WM, Sarkar M.
BACKGROUND& AIMS: Acetaminophen overdose is the leading cause of acute liver injury (ALI) and acute liver failure (ALF) in the developed world. Sex differences in acetaminophen-induced hepatotoxicity have not been described. METHODS: We collected ... (Source: SafetyLit)
Source: SafetyLit - December 6, 2017 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

The Checkup: Does an A.D.H.D. Link Mean Tylenol Is Unsafe in Pregnancy?
In a Norwegian study, pregnant women who took acetaminophen for 29 days or more had a more than twofold risk of having children with A.D.H.D. (Source: NYT Health)
Source: NYT Health - December 4, 2017 Category: Consumer Health News Authors: PERRI KLASS, M.D. Tags: Pregnancy and Childbirth Women and Girls Attention Deficit Hyperactivity Disorder Fever Tylenol (Drug) Source Type: news

Tips for surviving this cold and flu season
Don't overdo the over-the-counter meds: high doses of acetaminophen send nearly 60,000 people to the ER each year (Source: Health News: CBSNews.com)
Source: Health News: CBSNews.com - November 30, 2017 Category: Consumer Health News Source Type: news

Risks to watch for when taking cold and flu remedies
Last year, Americans reportedly spent nearly $6 billion on remedies for runny noses and sore throats. But over-the-counter medications can have risks. High doses of acetaminophen send nearly 60,000 people to the emergency room each year. Consumer Reports deputy editor Lisa Gill joins "CBS This Morning" to offer practical tips for the cold season. (Source: Health News: CBSNews.com)
Source: Health News: CBSNews.com - November 30, 2017 Category: Consumer Health News Source Type: news

Are ibuprofen plus acetaminophen as good as opioids in treating acute extremity pain
3.5 out of 5 stars Effect of a Single Dose of Oral Opioid and Nonopioid Analgesics on Acute Extremity Pain in the Emergency Department: A Randomized Clinical Trial. Chang AK et al. JAMA 2017;318:1661-1667. Abstract As Dr. Demetrios Kyriacou points out in a must-read editorial accompanying this paper, a growing body of evidence clearly indicates that even short-term opioid use for painful injuries or procedures carries a significant risk of leading to chronic use and potential abuse. We are now realizing the importance of avoiding even limited use of drugs such as oxycodone and hydrocodone in opioid-naive patients...
Source: The Poison Review - November 22, 2017 Category: Toxicology Authors: Leon Gussow Tags: Medical acute pain analgesic emergency department opioid Source Type: news

Ibuprofen and acetaminophen combination may be as effective as some opioids for acute extremity pain
According to a study published in the Nov. 7 issue of JAMA, single-dose treatment with ibuprofen and acetaminophen may be as effective as three different opioid and acetaminophen combination analgesics for reducing acute extremity pain in patients who present to the emergency department (ED).  (Source: Orthogate - Latest News)
Source: Orthogate - Latest News - November 11, 2017 Category: Orthopaedics Tags: Featured Editors Choice News Source Type: news

Ibuprofen + Acetaminophen Seems as Effective as Opioids + Acetaminophen for Acute Extremity Pain
Ibuprofen and opioids are similarly effective for short-term relief of acute extremity pain when combined with acetaminophen, according to a JAMA study. Some 400... (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - November 9, 2017 Category: Primary Care Source Type: news

OTC Painkillers Offer Similar Pain Relief as Opioids in ED OTC Painkillers Offer Similar Pain Relief as Opioids in ED
A combination of ibuprofen and acetaminophen was as effective as opioid-acetaminophen combinations in patients presenting to the emergency department with acute extremity pain in a randomized trial.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 8, 2017 Category: Consumer Health News Tags: Emergency Medicine News Source Type: news

Over-The-Counter Pain Relievers Worked As Well As Opioids In New Study
CHICAGO (AP) — Emergency rooms are where many patients are first introduced to powerful opioid painkillers, but what if doctors offered over-the-counter pills instead? A new study tested that approach on patients with broken bones and sprains and found pain relievers sold as Tylenol and Motrin worked as well as opioids at reducing severe pain. The results challenge common ER practice for treating short-term, severe pain and could prompt changes that would help prevent new patients from becoming addicted. The study has limitations: It only looked at short-term pain relief in the emergency room and researchers didn&rsq...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - November 7, 2017 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health Local News Confronting The Crisis opioid crisis Source Type: news

Prenatal exposure to acetaminophen and risk of ADHD - Ystrom E, Gustavson K, Brandlistuen RE, Knudsen GP, Magnus P, Susser E, Davey Smith G, Stoltenberg C, Sur én P, Håberg SE, Hornig M, Lipkin WI, Nordeng H, Reichborn-Kjennerud T.
OBJECTIVES: To estimate the association between maternal use of acetaminophen during pregnancy and of paternal use before pregnancy with attention-deficit/hyperactivity disorder (ADHD) in offspring while adjusting for familial risk for ADHD and indications... (Source: SafetyLit)
Source: SafetyLit - November 6, 2017 Category: International Medicine & Public Health Tags: Age: Infants and Children Source Type: news

Medical News Today: Acetaminophen during pregnancy is associated with ADHD
Acetaminophen use by pregnant women has previously been linked with ADHD in the offspring. A new study backs up these concerning findings. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 3, 2017 Category: Consumer Health News Tags: ADHD / ADD Source Type: news

An association between prenatal acetaminophen use and ADHD: the benefits of large data sets - Wolraich ML.
[Abstract unavailable] Language: en... (Source: SafetyLit)
Source: SafetyLit - November 2, 2017 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

Acetaminophen use in pregnancy linked to ADHD in study, but no cause is proven
Experts question new study linking long-term prenatal use with ADHD in the kids. (Source: ABC News: Health)
Source: ABC News: Health - October 31, 2017 Category: Consumer Health News Tags: Health Source Type: news

Lortab Elixir (Hydrocodone Bitartrate and Acetaminophen Oral Solution) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - October 31, 2017 Category: Drugs & Pharmacology Source Type: news

Lortab 2.5 (Hydrocodone Bitartrate and Acetaminophen Tablets) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - October 31, 2017 Category: Drugs & Pharmacology Source Type: news

Acetaminophen in Pregnancy Linked to ADHD in Kids
Maternal Use of Acetaminophen Linked to ADHD in Kids (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - October 31, 2017 Category: General Medicine Source Type: news

HealthWatch: Colonoscopies, Carbs, And A Link Between Tylenol And ADHD
BOSTON (CBS) — It’s generally recommended that people get their first colonoscopy at age 50, but after analyzing data on 6,000 procedures, French researchers say starting screening at age 45 could save lives. U.S. experts say there were some flaws with this study, so right now the American Cancer Society is standing by its recommendations to start screening at age 50 for people at average risk of developing colon cancer. If, however, you have a family history of colon cancer, you may need to be screened sooner. Does Tylenol Increase the Risk of ADHD in Offspring? Researchers in Norway found that pregnant moms w...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - October 30, 2017 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health Healthwatch Local News Seen On WBZ-TV Syndicated Local Dr. Mallika Marshall Source Type: news

Pain drugs in pregnancy tied to ADHD
(Reuters Health) - Women who use a lot of the common pain reliever acetaminophen during pregnancy may be more likely to have children with attention deficit hyperactivity disorder (ADHD) than those who don ’t use the drug, a Norwegian study suggests. (Source: Reuters: Health)
Source: Reuters: Health - October 30, 2017 Category: Consumer Health News Tags: healthNews Source Type: news

Maternal Use of Acetaminophen Linked to ADHD in Offspring
Link seen after adjustment for maternal use before pregnancy, familial risk for ADHD (Source: The Doctors Lounge - Psychiatry)
Source: The Doctors Lounge - Psychiatry - October 30, 2017 Category: Psychiatry Tags: Family Medicine, Gynecology, Infections, Neurology, Nursing, Pathology, Pediatrics, Pharmacy, Psychiatry, Rheumatology, Anesthesiology & amp; Pain, Journal, Source Type: news

Maternal Use of Acetaminophen Linked to ADHD in Kids Maternal Use of Acetaminophen Linked to ADHD in Kids
The risk is related to duration of use, but the causal relationship is still questionable, authors caution.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - October 30, 2017 Category: Consumer Health News Tags: Pediatrics News Source Type: news

Acetaminophen during pregnancy tied to ADHD risk in kids
A new study adds to evidence linking extended use of the medication to an increased risk of behavioral issues in children (Source: Health News: CBSNews.com)
Source: Health News: CBSNews.com - October 30, 2017 Category: Consumer Health News Source Type: news

Acetaminophen in Pregnancy Tied to ADHD Risk
Acetaminophen is considered the go-to pain medication during pregnancy. But a new study adds to evidence linking the drug to an increased risk of behavioral issues in kids. (Source: WebMD Health)
Source: WebMD Health - October 30, 2017 Category: Consumer Health News Source Type: news

Acetaminophen in Pregnancy Tied to ADHD Risk in Kids
Source: HealthDay Related MedlinePlus Pages: Attention Deficit Hyperactivity Disorder, Pregnancy and Medicines (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - October 30, 2017 Category: Consumer Health News Source Type: news

An Asian-American adolescent with a suicide attempt - Nissirios KS, Levitt WG, Pimentel J.
A 15-year-old Asian-American girl who was enrolled in high school and lived with her parents and two older sisters attempted suicide by ingesting 25 tablets of acetaminophen (each of which were 325 mg). The patient reported that her stress was triggered by... (Source: SafetyLit)
Source: SafetyLit - October 30, 2017 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

Acetaminophen in Pregnancy Tied to ADHD Risk in Kids
MONDAY, Oct. 30, 2017 -- Acetaminophen is considered the go-to pain medication during pregnancy. But a new study adds to evidence linking the drug to an increased risk of behavioral issues in kids. Researchers in Norway found that among nearly... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - October 30, 2017 Category: General Medicine Source Type: news

Study links acetaminophen in pregnancy to ADHD
Long-term use of acetaminophen during pregnancy was associated with twice the risk of attention-deficit hyperactivity disorder in children, according to a study published Monday in the journal Pediatrics. However, two experts believe that the data do not support these findings. (Source: CNN.com - Health)
Source: CNN.com - Health - October 30, 2017 Category: Consumer Health News Source Type: news

Long-Term Acetaminophen Use in Pregnancy Tied to ADHD in Offspring (FREE)
By Amy Orciari Herman Edited by Susan Sadoughi, MD, and Andr é Sofair, MD, MPH Long-term use of acetaminophen during pregnancy is associated with increased risk for attention-deficit/hyperactivity disorder in offspring, a Pediatrics study suggests. The researchers caution, however, that their data can't prove … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - October 30, 2017 Category: Primary Care Source Type: news

What is Usher Syndrome?
Discussion Over 7000 diseases are considered rare disorders according to the National Organization for Rare Disorders® (NORD, rarediseases.org). NORD is a patient advocacy organization dedicated to individuals with rare diseases and the organizations that serve them. They have information on about 1200 rare diseases on their website (https://rarediseases.org/for-patients-and-families/information-resources/rare-disease-information/). Hearing loss (HL) is not rare and is a common problem across the ages. It affects 360 million people worldwide which is about 5% of the population. There are many causes of hearing loss an...
Source: PediatricEducation.org - October 23, 2017 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Easy Fix for Post-Op Shivers?
SATURDAY, Oct. 21, 2017 -- Giving patients acetaminophen during surgery may reduce their risk of shivering when they wake up, according to a small study. Up to half of patients have shivers and chills when they regain consciousness after surgery.... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - October 21, 2017 Category: General Medicine Source Type: news

Acetaminophen may help reduce postoperative shivering
(American Society of Anesthesiologists) Administering acetaminophen, such as Tylenol, during surgery may reduce the incidence of postoperative shivering, suggests a study being presented at the ANESTHESIOLOGY ® 2017 annual meeting. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 21, 2017 Category: International Medicine & Public Health Source Type: news

Darvocet-N (Propoxyphene Napsylate and Acetaminophen) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - October 12, 2017 Category: Drugs & Pharmacology Source Type: news

Fever in pregnancy causes heart, facial birth defects
Fever in early pregnancy can lead to heart and facial defects in a fetus, a new study from Duke University reveals. Researchers say that taking acetaminophen may prevent defects. (Source: the Mail online | Health)
Source: the Mail online | Health - October 10, 2017 Category: Consumer Health News Source Type: news

Psychosocial and behavioral factors in acetaminophen-related acute liver failure and liver injury - Pezzia C, Sanders C, Welch S, Bowling A, Lee WM.
OBJECTIVES: Acetaminophen overdoses result in nearly 500 deaths annually and a much larger number of hospitalizations. Suicidal overdoses are exceeded in number in the United States by unintentional overdoses. We evaluated clinical, demographic and psychos... (Source: SafetyLit)
Source: SafetyLit - September 7, 2017 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Increased acetaminophen related calls to Finnish PIC better reflect acetaminophen sales than serious poisonings - Parry MJ, Isoniemi H, Koivusalo AM, Hoppu K.
OBJECTIVE: Acetaminophen (APAP) or paracetamol is a commonly encountered medicine in poisonings. We studied the changes in APAP related calls to the Finnish poison information centre (FPIC), and serious intoxications, involving hepatotoxicity or death in 2... (Source: SafetyLit)
Source: SafetyLit - August 25, 2017 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Orbivan (Butalbital, Acetaminophen, and Caffeine Capsules, USP) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - August 24, 2017 Category: Drugs & Pharmacology Source Type: news