How Remdesivir Moved From Back Shelf to Best Hope for Treating COVID-19
This study showed that a five-day regimen is as effective as 10 days–that’s important, doctors say, since it could mean shorter stays in the hospital, which could alleviate some of the burden on the health care system. “Of course we will have to wait for the final review of all the data, but it would be very nice to have an anti-viral that’s efficacious in this terrible illness,” says Dr. Aruna Subramanian, a clinical professor of medicine at Stanford and an investigator on the study. “At least we know that we can help patients with this, and that’s really the bottom line.” T...
Source: TIME: Health - May 21, 2020 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized COVID-19 feature Magazine Source Type: news

Acetaminophen poisoning: reclaiming the definition of recovery - DiSalvo PC, Chiang WK, Wang JJ.
[Abstract unavailable] Language: en... (Source: SafetyLit)
Source: SafetyLit - May 16, 2020 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

The Role of Circulating Cell-Free Hemoglobin in Sepsis-Associated Acute Kidney Injury
Summary: Sepsis is a heterogeneous clinical syndrome that is complicated commonly by acute kidney injury (sepsis-AKI). Currently, no approved pharmacologic therapies exist to either prevent sepsis-AKI or to treat sepsis-AKI once it occurs. A growing body of evidence supports a connection between red blood cell biology and sepsis-AKI. Increased levels of circulating cell-free hemoglobin (CFH) released from red blood cells during hemolysis are common during sepsis and can contribute to sepsis-AKI through several mechanisms including tubular obstruction, nitric oxide depletion, oxidative injury, and proinflammatory signaling....
Source: Current Awareness Service for Health (CASH) - May 6, 2020 Category: Consumer Health News Source Type: news

I Thought I Could Handle Anything. Then My Husband Got Sick
When my husband began to show symptoms of COVID-19, about a week after we found out one of his coworkers on a building site in New York City had a positive test, I wasn’t particularly worried. He’s a middle-aged, athletic, healthy guy. Our kids live elsewhere. We would just hunker down for a few days and get through it together. After all, the pandemic has forced many people to do work that they have traditionally outsourced. Families are homeschooling, cleaning their own homes, cooking more meals, doing their own home repairs. Even if nobody in their home has fallen ill, people have had to behave more like hea...
Source: TIME: Health - April 29, 2020 Category: Consumer Health News Authors: Belinda Luscombe Tags: Uncategorized COVID-19 Source Type: news

9 Things That Helped Me Get Through My Mild COVID-19 Infection
It was 3 a.m. and I was lying in bed listening to ambulance sirens. Nighttime is usually quiet in my Brooklyn neighborhood, but not in recent weeks. Wrapped like a burrito in my heavy comforter with another blanket draped over me, I was still cold. The thermometer hadn’t strayed from 101.2° Fahrenheit since 11 p.m., which was when I arranged myself in bed in this position, staying very still. My head was throbbing as if I were suspended upside down in the air, and my chest was heavy. It felt like something could explode internally if I breathed in too deeply. Also, I was alone. That’s usually not a prob...
Source: TIME: Health - April 23, 2020 Category: Consumer Health News Authors: Jessica Firger Tags: Uncategorized COVID-19 Source Type: news

Recommended Warning for Over-the-Counter Acetaminophen-Containing Drug Products and Labeling Statements Regarding Serious Skin Reactions
Compliance; Over-the-Counter (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - April 15, 2020 Category: Drugs & Pharmacology Authors: FDA Source Type: news

Granules India gets USFDA approval for Butalbital, Acetaminophen, Caffeine capsules
​Butalbital, Acetaminophen and Caffeine Capsules are used to treat tension headaches. ​Butalbital, Acetaminophen and Caffeine Capsules USP, 50 mg/300 mg/40 mg had US sales of approximately 42 million dollar MAT for the most recent twelve months ending in February, 2020 according to IQVIA Health. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - April 8, 2020 Category: Pharmaceuticals Source Type: news

Pandemic-linked Tylenol shortages popping up in some places
Its main ingredient, acetaminophen, has come to be seen as safer than medications containing ibuprofen to treat fever, a frequent symptom of the new coronavirus. (Source: Health News: CBSNews.com)
Source: Health News: CBSNews.com - April 7, 2020 Category: Consumer Health News Source Type: news

Coronavirus: How To Quarantine Properly If You ’ re Infected
(CNN) — It’s a scenario all too many of us are facing — or will soon face. You or a loved one has a mild fever, body aches, the start of a nagging, dry cough. Food doesn’t taste good nor smell as it once did. Maybe you have shortness of breath or struggle to breath deeply. You’ve called your doctor, and you are suddenly face-to-face with the scary reality of Covid-19. What happens next depends on your specific circumstances. If you are having trouble breathing or are elderly and fragile, you may be hospitalized and tested for the virus. If you’re not in immediate danger but potentially h...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - March 30, 2020 Category: Consumer Health News Authors: Health – CBS Boston Tags: Boston News Featured Health CNN Coronavirus quarantine Source Type: news

WHO clarifies guidance on ibuprofen, says there's no evidence it can worsen COVID-19
The World Health Organization has said there's no evidence to suggest that using ibuprofen to manage symptoms of COVID-19 will worsen the condition, but some other health authorities say it makes sense to use acetaminophen as a first choice instead.  (Source: CBC | Health)
Source: CBC | Health - March 18, 2020 Category: Consumer Health News Tags: News/Health Source Type: news

Are the French Right to Warn Against NSAID Use in COVID-19? Are the French Right to Warn Against NSAID Use in COVID-19?
The French Health Ministry recommends acetaminophen instead, but evidence on any unique COVID-19-related effects linked to ibuprofen is lacking, say the Spanish Health Ministry and a US expert.Medscape Medical News (Source: Medscape Orthopaedics Headlines)
Source: Medscape Orthopaedics Headlines - March 17, 2020 Category: Orthopaedics Tags: Infectious Diseases News Source Type: news

Are Warnings Against NSAIDs in COVID-19 Warranted? Are Warnings Against NSAIDs in COVID-19 Warranted?
The French Health Ministry recommends acetaminophen instead, but evidence on any unique COVID-19-related effects linked to ibuprofen is lacking, say the Spanish Health Ministry and a US expert.Medscape Medical News (Source: Medscape Pharmacist Headlines)
Source: Medscape Pharmacist Headlines - March 17, 2020 Category: Drugs & Pharmacology Tags: Infectious Diseases News Source Type: news

Alcohol Consumption and Severity of Acute Liver Injury Alcohol Consumption and Severity of Acute Liver Injury
This study suggests that even moderate alcohol consumption increases the severity and clinical course of liver injury in acetaminophen as well as non-acetaminophen acute liver failure.Liver International (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 17, 2020 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

FDA approves GSK ’s Advil Dual Action with Acetaminophen for over-the-counter use in the United States
First combination of ibuprofen and acetaminophen for pain relief to be available OTC in 2020Issued: Warren, USGlaxoSmithKline (LSE/NYSE: GSK) today announced that the U.S. Food and Drug Administration (FDA) has approved Advil Dual Action with Acetaminophen as an over-the-counter (OTC) product for pain relief. The exclusive formula is now the first FDA-approved OTC combination of ibuprofen and acetaminophen in the United States and will be available over-the-counter nationwide in 2020.Franck Riot, Head of R&D, GSK Consumer Healthcare said: “For decades, many consumers have been using ibuprofen and acetaminophen to get...
Source: Dental Technology Blog - March 6, 2020 Category: Dentistry Source Type: news

What Causes Neutropenia?
Discussion Neuropenia is defined as a neutrophil count < 1500/µL. It is classified as mild from 1000-1500/µL, moderate from 500-1000/µL, and severe if < 500/µL. It is not uncommonly seen in the setting of acute self-limited infections, and with re-testing returns to normal. It is also not uncommon at certain ages, such as perinatally, especially in premature infants (up to 6%) . It is also common in certain ethnic groups particularly African American or Arabic populations where up to 10% of the children may have mild neutropenia which does not cause clinical disease. The overall prevalence a...
Source: PediatricEducation.org - March 2, 2020 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news