Performance of the paracetamol-aminotransferase multiplication product in risk stratification after paracetamol (acetaminophen) poisoning: a systematic review and meta-analysis - Yau CE, Chen H, Lim BPY, Ng M, Ponampalam R, Lim DYZ, Chin YH, Ho AFW.
BACKGROUND: Risk stratification in paracetamol (acetaminophen) poisoning is crucial because hepatotoxicity is common and can be mitigated with treatment. However, current risk stratification tools have limitations. AIMS: We evaluated the diagnostic perform... (Source: SafetyLit)
Source: SafetyLit - December 5, 2022 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Acetaminophen toxicity and overdose: current understanding and future directions for NAC dosing regimens - Jankovic SM.
INTRODUCTION: Although N-acetyl-cysteine (NAC) has long been used for the treatment of acetaminophen poisoning/overdose, the optimal NAC dosing regimen for varying patterns or severity of the poisoning/overdose is still unknown. AREAS COVERED: Relevant lit... (Source: SafetyLit)
Source: SafetyLit - November 30, 2022 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Small victories: South Africa is struggling to improve kids ’ health decades after apartheid’s demise
KWAZULU-NATAL, SOUTH AFRICA— By her country’s standards at the time, there was nothing too unusual about how Nosipho Mshengu arrived in the world. She was born on the side of the road on 20 September 1993, as her mother tried to get from Mafakatini, a rural village in South Africa where there was then no health facility, to a Roman Catholic clinic an hour away. The bus she awaited was nowhere in sight when time ran out, and Mshengu made her entry then and there. This story was supported by the Pulitzer Center. A little more than 14 years later, Mshengu was pregnant herself. Her labor story...
Source: ScienceNOW - November 22, 2022 Category: Science Source Type: news

Shortage of children's pain relievers is crowding the ER — but there are solutions, doctors say
With the cold and flu season in full swing in many parts of Canada — and new COVID variants arising worldwide — supplies of pain medications containing acetaminophen and ibuprofen remain short on pharmacy shelves and parents are looking for options. So parents are tuning to the ER. (Source: CBC | Health)
Source: CBC | Health - November 4, 2022 Category: Consumer Health News Tags: News/Canada Source Type: news

Janssen to Highlight Latest Scientific Advances in Hematologic Diseases at ASH 2022 with Clinical and Real-World Data Across Innovative Pipeline and Distinguished Portfolio
RARITAN, N.J., November 3, 2022 – The Janssen Pharmaceutical Companies of Johnson & Johnson are committed to redefining treatment outcomes in the hematology setting and today announced that abstracts from more than 50 company-sponsored studies, plus more than 20 investigator-initiated studies, will be presented at the American Society of Hematology (ASH) Annual Meeting in New Orleans from December 10-13, 2022. Janssen’s commitment to advancing an innovative portfolio of therapies for healthcare professionals and patients is evidenced through more than 70 presentations that span clinical studies and r...
Source: Johnson and Johnson - November 3, 2022 Category: Pharmaceuticals Tags: Innovation Source Type: news

Acetaminophen
: FDA encourages the safe use of over-the-counter (OTC) and prescription (Rx) pain medicines. The FDA has taken action to improve the safety of consumers when using acetaminophen. Information for use during pregnancy, in children, and risk of rare skin disease is provided to help consumers make safer choices. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - November 2, 2022 Category: Drugs & Pharmacology Authors: FDA Source Type: news

Debate over possible acetaminophen-autism link heads to court
Debate over the growing scientific evidence that links women who took acetaminophen during pregnancy with having a child with autism is heading to the courtroom. (Source: Health News - UPI.com)
Source: Health News - UPI.com - October 28, 2022 Category: Consumer Health News Source Type: news

Debate heads to court over possible acetaminophen-autism link
Debate over the growing scientific evidence that links women who took acetaminophen during pregnancy with having a child with autism is heading to the courtroom. (Source: Health News - UPI.com)
Source: Health News - UPI.com - October 28, 2022 Category: Consumer Health News Source Type: news

Risk-Benefit of Opioids, Other Analgesics Prescribed in ED Unclear
TUESDAY, Oct. 18, 2022 -- The balance of risks and benefits is unclear for opioids compared with placebo, acetaminophen, nonsteroidal anti-inflammatory drugs (NSAIDs), and local or systemic anesthetics prescribed for musculoskeletal pain in the... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - October 18, 2022 Category: Pharmaceuticals Source Type: news

Acetaminophen Exposure in Utero Tied to Child Neurobehavioral Problems
Problems with sleep, attention seen at age 3 years in children exposed to acetaminophen in utero (Source: The Doctors Lounge - Psychiatry)
Source: The Doctors Lounge - Psychiatry - October 5, 2022 Category: Psychiatry Tags: Family Medicine, Gynecology, Neurology, Pediatrics, Pharmacy, Psychiatry, Anesthesiology & amp; Pain, Journal, Source Type: news

Acetaminophen Exposure in Utero Tied to Child Neurobehavioral Problems
WEDNESDAY, Oct. 5, 2022 -- Exposure to acetaminophen during pregnancy is associated with attention and sleep problems in offspring at age 3 years, according to a study published online Sept. 28 in PLOS ONE. Kristin K. Sznajder, Ph.D., M.P.H., from... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - October 5, 2022 Category: Pharmaceuticals Source Type: news

Drug-induced lung injury caused by acetaminophen in a Japanese woman: a case report - Fujii M, Kenzaka T.
BACKGROUND: All drugs have the potential to cause drug-induced lung injury both during and after drug administration. Acetaminophen has been reported to cause drug-induced lung injury, although this is extremely rare. Herein, we present an extremely rare c... (Source: SafetyLit)
Source: SafetyLit - October 5, 2022 Category: International Medicine & Public Health Tags: Home and Consumer Product Safety Source Type: news

Acetaminophen use during pregnancy can impact kids' behavior, researchers warn
Acetaminophen is widely taken during pregnancy, but a new study warns women that it may be linked to sleep and attention problems in children. They were discovered in kids at age 3. (Source: Health News - UPI.com)
Source: Health News - UPI.com - September 29, 2022 Category: Consumer Health News Source Type: news

Pregnant women who take Tylenol 'more likely to have children with ADHD and behavioural problems' 
Penn State University researchers found children were more likely to have attention problems or difficulty sleeping by age three if their moms used acetaminophen - the generic name for Tylenol. (Source: the Mail online | Health)
Source: the Mail online | Health - September 27, 2022 Category: Consumer Health News Source Type: news

Is Acetaminophen Really Safer Than NSAIDs in Heart Disease? Is Acetaminophen Really Safer Than NSAIDs in Heart Disease?
A new analysis finds a significant correlation between acetaminophen use and elevated systolic blood pressure, calling into question the assumption it ' s safer than NSAIDs in those with heart disease.Medscape Medical News (Source: Medscape Rheumatology Headlines)
Source: Medscape Rheumatology Headlines - September 15, 2022 Category: Rheumatology Tags: Cardiology News Source Type: news