Strides Pharma Science arm gets USFDA nod for tension headache tablets
Strides Pharma Global Pte Ltd, Singapore, has received approval for Butalbital, Acetaminophen, and Caffeine tablets USP in the strengths of 50 mg/325 mg/40 mg from the United States Food and Drug Administration (USFDA), Strides Pharma Science said in a regulatory filing. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - September 21, 2020 Category: Pharmaceuticals Source Type: news

A Popular Pain Reliever Can Alter Risk Perception
Past research has shown that Tylenol's active ingredient, acetaminophen, can sway emotions, and in some cases, relieve hurt feelings. A new study shows that it might subtly nudge people to take risks. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - September 15, 2020 Category: Pharmaceuticals Authors: Jackie Rocheleau, Contributor Tags: Healthcare /healthcare Innovation /innovation Science /science Source Type: news

Effects of acetaminophen on risk taking - Keaveney A, Peters E, Way B.
Acetaminophen, an analgesic and antipyretic available over-the-counter and used in over 600 medicines, is one of the most consumed drugs in the USA. Recent research has suggested that acetaminophen's effects extend to the blunting of negative as well as po... (Source: SafetyLit)
Source: SafetyLit - September 8, 2020 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

A pain reliever that alters perceptions of risk
(Ohio State University) While acetaminophen is helping you deal with your headache, it may also be making you more willing to take risks, a new study suggests.People who took acetaminophen rated activities like " bungee jumping off a tall bridge " and " speaking your mind about an unpopular issue in a meeting at work " as less risky than people who took a placebo, researchers found. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - September 8, 2020 Category: International Medicine & Public Health Source Type: news

What Is In A Ketogenic Diet?
Discussion Epilepsy is a common problem for the general pediatrician. Its incidence is estimated at 41-87/100,000 children. While many children are controlled with medication, it is also estimated that up to 1/3 will develop drug-resistant epilepsy. Some children may have an identifiable seizure focus that may be amenable to surgery, but many others do not. One option for potential control is a ketogenic diet (KD). Indications for KD usually are for drug-resistant epilepsy including partial and complex seizure patterns as well as some metabolic disorders such as glucose transport 1 deficiency syndrome. It has also found ...
Source: PediatricEducation.org - September 7, 2020 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Acetaminophen Use Linked to False-Positive Test for Chronic Granulomatous Disease Acetaminophen Use Linked to False-Positive Test for Chronic Granulomatous Disease
Recent acetaminophen use can lead to a false positive result on the dihydrorhodamine test, new findings show.Reuters Health Information (Source: Medscape Allergy Headlines)
Source: Medscape Allergy Headlines - August 5, 2020 Category: Allergy & Immunology Tags: Allergy & Clinical Immunology News Source Type: news

Current etiological comprehension and therapeutic targets of acetaminophen-induced hepatotoxicity - Chowdhury A, Jahan N, Adelusi Temitope I, Wang S.
Acetaminophen (APAP) is the most popular mild analgesic and antipyretic drug used worldwide. APAP overdose leads to drug-induced hepatotoxicity and can cause hepatic failure if treatment delayed. It is adequately comprehended that the metabolism of high-do... (Source: SafetyLit)
Source: SafetyLit - August 4, 2020 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Another Voice: The Proposition 65 headache
No one likes headaches. They are painful and uncomfortable, and even though we do everything we can to stop one with water, food or relaxation, sometimes these just don ’t solve it. Like many others, I sometimes take acetaminophen, better known as Tylenol, to help. For decades, it has been a trustworthy staple in everyone’s medicine cabinet, and I recommend it regularly to many of my patients in the emergency department. Right now though, acetaminophen is o n the track to be misleadingly classified… (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - July 31, 2020 Category: Pharmaceuticals Authors: Dr. Adam Dougherty Source Type: news

Increase Found in Suicide - Related Exposure Rates to OTC Analgesics
Acetaminophen, acetylsalicylic acid accounted for 48.0, 18.5 percent of cases; 64.5, 32.6 percent of deaths (Source: The Doctors Lounge - Psychiatry)
Source: The Doctors Lounge - Psychiatry - July 28, 2020 Category: Psychiatry Tags: Family Medicine, Internal Medicine, Critical Care, Emergency Medicine, Pediatrics, Pharmacy, Psychiatry, Journal, Source Type: news

Late diagnosis of paracetamol poisoning is always lethal in young adult - Naz S, Fatima S, Aamir M.
Acetaminophen has a remarkable safety profile when prescribed in proper therapeutic doses, but hepatotoxicity can occur when misused or after an overdose. The principal toxic metabolite of acetaminophen is N-acetyl-p-benzoquinone imine (NAPQI). Toxicity sh... (Source: SafetyLit)
Source: SafetyLit - July 27, 2020 Category: International Medicine & Public Health Tags: Age: Young Adults Source Type: news

Liver injury induced by paracetamol and challenges associated with intentional and unintentional use - Rotundo L, Pyrsopoulos N.
Drug induced liver injury (DILI) is a common cause of acute liver injury. Paracetamol, also known as acetaminophen, is a widely used anti-pyretic that has long been established to cause liver toxicity once above therapeutic levels. Hepatotoxicity from para... (Source: SafetyLit)
Source: SafetyLit - July 23, 2020 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Zydus Cadila gets final approval from USFDA to market generic tension headache tablets
The company has received final approval from the United States Food and Drug Administration (USFDA) to market Butalbital, Acetaminophen and Caffeine tablets in strengths of 50mg/325mg/40 mg, Zydus Cadila said in a statement. The drug will be manufactured at Nesher Pharma's manufacturing facility at St. Louis in the US, it added. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - July 17, 2020 Category: Pharmaceuticals Source Type: news

Acetaminophen Beats Fentanyl in STEMI Acetaminophen Beats Fentanyl in STEMI
Acetaminophen during and after PCI in the ON-TIME 3 trial relieved pain as well as fentanyl but didn ' t depress ticagrelor blood levels.Medscape Medical News (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - July 15, 2020 Category: Cardiology Tags: Cardiology News Source Type: news

Subcutaneous Daratumumab Combination Resulted in Deep and Rapid Hematologic Responses and Improved Clinical Outcomes in the Treatment of Patients with Newly Diagnosed Light Chain (AL) Amyloidosis
RARITAN, NJ, June 13, 2020 – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today results from the first randomized Phase 3 study investigating subcutaneous daratumumab[i] in the treatment of patients with newly diagnosed light chain (AL) amyloidosis, a rare and potentially fatal disease.[1],[2] The data demonstrated subcutaneous daratumumab in combination with cyclophosphamide, bortezomib, and dexamethasone (D-CyBorD) resulted in a higher hematologic complete response rate (CR), (53 percent vs. 18 percent [P<0.0001]), compared to CyBorD. Additionally, treatment with D-CyBorD delayed the time ...
Source: Johnson and Johnson - June 15, 2020 Category: Pharmaceuticals Tags: Innovation Source Type: news

Stocks of paracetamol products stored in urban New Zealand households: a cross-sectional study - Kumpula EK, Norris P, Pomerleau AC.
BACKGROUND: Intentional self-harm is a common cause of hospital presentations in New Zealand and across the world, and self-poisoning is the most common method of self-harm. Paracetamol (acetaminophen) is frequently used in impulsive intentional overdoses,... (Source: SafetyLit)
Source: SafetyLit - June 4, 2020 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news