The Association of Arsenic Metabolism with Cancer, Cardiovascular Disease, and Diabetes: A Systematic Review of the Epidemiological Evidence

Conclusions: Population level of iAs% and DMA%, but not MMA%, were associated with arsenic exposure levels. Overall, study findings suggest that higher MMA% was associated with an increased risk of cancer and cardiovascular disease, while lower MMA% was associated with an increased risk of diabetes and metabolic syndrome. Additional population-based studies and experimental studies are needed to further evaluate and understand the role of arsenic exposure in arsenic metabolism and the role of arsenic metabolism in disease development. https://doi.org/10.1289/EHP577 Received: 01 June 2016 Revised: 26 February 2017 Accepted: 27 February 2017 Published: 01 August 2017 Address correspondence to C.C. Kuo, Kidney Institute and Div. of Nephrology, Dept. of Internal Medicine, and Big Data Center, China Medical University Hospital and College of Medicine, China Medical University, 2 Yude Rd., North Dist., Taichung City 404, Taiwan. Telephone: 886-4-2205-2121-2913. Email: chinchik@gmail.com Supplemental Material is available online (https://doi.org/10.1289/EHP577). The authors declare they have no actual or potential competing financial interests. Note to readers with disabilities: EHP strives to ensure that all journal content is accessible to all readers. However, some figures and Supplemental Material published in EHP articles may not conform to 508 standards due to the complexity of the information being presented. If you need assistance accessing journal...
Source: EHP Research - Category: Environmental Health Authors: Tags: Research Source Type: research

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This study aims to reflect on the process of adoption of the preprints publication model, briefly delimiting its history and current use by the national and the international scientific community. Departing from the literature and a consultation of preprint repositories, this reflection intends to highlight the main challenges that preprint implementation will face in the Nursing area, along with its specificities. While considering its benefits for scientific dissemination, this study points out the difficulties that may arise from the implementation of mostly north-American science models in a peripheral country such as ...
Source: Revista da Escola de Enfermagem da USP - Category: Nursing Source Type: research
There is evidence that an ancient Chinese form of martial arts improves your mind and body, and may even contribute to a longer life.
Source: CNN.com - Health - Category: Consumer Health News Source Type: news
More than a third of patients with diabetes don't take their drugs as prescribed, sometimes because of cost concerns.
Source: Health News: CBSNews.com - Category: Consumer Health News Source Type: news
Authors: Ashrafi MR, Amanat M, Garshasbi M, Kameli R, Nilipour Y, Heidari M, Rezaei Z, Tavasoli AR Abstract Introduction: Leukodystrophies constitute heterogenous group of rare heritable disorders primarily affecting the white matter of central nervous system. These conditions are often under-appreciated among physicians. The first clinical manifestations of leukodystrophies are often nonspecific and can occur in different ages from neonatal to late adulthood periods. The diagnosis is, therefore, challenging in most cases.Area covered: Herein, the authors discuss different aspects of leukodystrophies. The authors used...
Source: Expert Review of Neurotherapeutics - Category: Neurology Tags: Expert Rev Neurother Source Type: research
Conclusions: In patients discontinuing natalizumab, fingolimod has a favorable benefit–risk profile over 48 months. These findings also suggest using a short washout following natalizumab discontinuation, consistent with guidelines and current clinical practice in Germany.
Source: Multiple Sclerosis and Related Disorders - Category: Neurology Source Type: research
Publication date: Available online 13 December 2019Source: Brain, Behavior, and ImmunityAuthor(s): N.B. Teixeira, M.B. Sant'Anna, A.C. Giardini, L.P. Araujo, L.A. Fonseca, A.S. Basso, Y. Cury, G. PicoloAbstractMultiple sclerosis (MS) is a Central Nervous System inflammatory demyelinating disease that has as primary symptoms losses of sensory and motor functions, including chronic pain. To date, however, few studies have investigated the mechanisms of chronic pain in animal models of MS since locomotor impairments render difficult its evaluation. It was previously demonstrated that in the MOG35-55-induced EAE, an animal mod...
Source: Brain, Behavior, and Immunity - Category: Neurology Source Type: research
Ceribell Inc., the company that set out to simplify bedside electroencephalogram (EEG) monitoring with its Ceribell Rapid Response EEG and took home the 2019 Medical Design Excellence Awards Best-in-Show award, has just launched Clarity, a new 24/7 bedside EEG monitoring and alerting technology. The company made the announcement at the American Epileptology Society Annual Meeting. Ceribell Rapid Response EEG was designed to ease EEG setup and triage for patients with suspicion of seizure, and application does not require an EEG technician. In addition to winning the MDEA Best in Show, the system was also recognized with a ...
Source: MDDI - Category: Medical Devices Authors: Tags: Software Source Type: news
Among women with metastatic breast cancer, use of an investigational oral form of paclitaxel yielded a higher overall response rate than the IV form, but administration was unique and time-consuming.Medscape Medical News
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news
Publication date: 14–20 December 2019Source: The Lancet, Volume 394, Issue 10215Author(s): Mohammed A Mamun, Jannatul Mawa Misti, Mark D Griffiths, David Gozal
Source: The Lancet - Category: General Medicine Source Type: research
Publication date: 14–20 December 2019Source: The Lancet, Volume 394, Issue 10215Author(s): Helena Hui Wang, Richard Horton
Source: The Lancet - Category: General Medicine Source Type: research
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