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Ambient Ozone Pollution and Daily Mortality: A Nationwide Study in 272 Chinese Cities
Conclusions: Our findings provide robust evidence of higher nonaccidental and cardiovascular mortality in association with short-term exposure to ambient ozone in China. https://doi.org/10.1289/EHP1849 Received: 4 March 2017 Revised: 3 October 2017 Accepted: 20 October 2017 Published: 21 November 2017 Address correspondence to H. Kan, Department of Environmental Health, School of Public Health, Fudan University, P.O. Box 249, 130 Dong-An Road, Shanghai 200032, China. Telephone: 86 (21) 5423 7908. Email: kanh@fudan.edu.cn and M. Zhou, National Center for Chronic and Noncommunicable Disease Control and Prevention, Chines...
Source: EHP Research - November 21, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

Long-Term Exposure to Transportation Noise in Relation to Development of Obesity —a Cohort Study
Conclusion: Our results link transportation noise exposure to development of obesity and suggest that combined exposure from different sources may be particularly harmful. https://doi.org/10.1289/EHP1910 Received: 17 March 2017 Revised: 5 October 2017 Accepted: 9 October 2017 Published: 20 November 2017 Address correspondence to A. Pyko, Institute of Environmental Medicine, Karolinska Institutet, SE-171 77 Stockholm, Sweden. Telephone: 46(0) 852487561. Email: Andrei.pyko@ki.se Supplemental Material is available online (https://doi.org/10.1289/EHP1910). The authors declare they have no actual or potential competing fina...
Source: EHP Research - November 20, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

Exposure to Perfluoroalkyl Substances and Metabolic Outcomes in Pregnant Women: Evidence from the Spanish INMA Birth Cohorts
Conclusions: Although further confirmation is required, the findings from this study suggest that PFAS exposures during pregnancy may influence lipid metabolism and glucose tolerance and thus may impact the health of the mother and her child. https://doi.org/10.1289/EHP1062 Received: 7 September 2016 Revised: 5 October 2017 Accepted: 9 October 2017 Published: 13 November 2017 Address correspondence to M. Vrijheid, ISGlobal, Centre for Research in Environmental Epidemiology (CREAL), 88 Doctor Aiguader, 08003 Barcelona, Catalonia, Spain. Telephone: 93 214 73 46. Email: martine.vrijheid@isglobal.org Supplemental Material ...
Source: EHP Research - November 13, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

Early-Life Selenium Status and Cognitive Function at 5 and 10 Years of Age in Bangladeshi Children
Conclusions: Measures of prenatal and childhood (below the 98th percentile) selenium status were associated with higher cognitive function scores at 5 and 10 y of age. https://doi.org/10.1289/EHP1691 Received: 30 January 2017 Revised: 20 September 2017 Accepted: 21 September 2017 Published: 07 November 2017 Address correspondence to M. Kippler, Institute of Environmental Medicine, Karolinska Institutet, Box 210, SE-171 77, Stockholm, Sweden. Telephone: 46 8 524 874 07. Email: maria.kippler@ki.se Supplemental Material is available online (https://doi.org/10.1289/EHP1691). The authors declare they have no actual or pot...
Source: EHP Research - November 7, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

Long-term Fine Particulate Matter Exposure and Nonaccidental and Cause-specific Mortality in a Large National Cohort of Chinese Men
Conclusions: Long-term exposure to PM2.5 was associated with nonaccidental, CVD, lung cancer, and COPD mortality in China. The IER estimator may underestimate the excess relative risk of cause-specific mortality due to long-term exposure to PM2.5 over the exposure range experienced in China and other low- and middle-income countries. https://doi.org/10.1289/EHP1673 Received: 24 February 2017 Revised: 01 September 2017 Accepted: 05 September 2017 Published: 07 November 2017 Address correspondence to M. Zhou, National Center for Chronic Noncommunicable Disease Control and Prevention, Chinese Center for Disease Control ...
Source: EHP Research - November 7, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

From Intuitive to Evidence Based: Developing the Science of Nature as a Public Health Resource
PDF Version (1.1 MB) About This Article Published: 6 November 2017 Note to readers with disabilities: EHP strives to ensure that all journal content is accessible to all readers. However, some figures and Supplemental Material published in EHP articles may not conform to 508 standards due to the complexity of the information being presented. If you need assistance accessing journal content, please contact ehponline@niehs.nih.gov. Our staff will work with you to assess and meet your accessibility needs within 3 working days.  Related EHP Article Nature Contact and Human Health: A Resea...
Source: EHP Research - November 6, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Science Selection Source Type: research

Biological Cleavage of the C –P Bond in Perfluoroalkyl Phosphinic Acids in Male Sprague-Dawley Rats and the Formation of Persistent and Reactive Metabolites
Conclusions: PFPiAs were metabolized in Sprague-Dawley rats to form persistent PFPAs as well as 1H-PFAs, which contain a labile hydrogen that may undergo further metabolism. These results in rats produced preliminary findings of the pharmacokinetics and metabolism of PFPiAs, which should be further investigated in humans. If there is a parallel between the disposition of these chemicals in humans and rats, then humans with detectable amounts of PFPiAs in their blood may be undergoing continuous exposure. https://doi.org/10.1289/EHP1841 Received: 1 March 2017 Revised: 20 September 2017 Accepted: 21 September 2017 Publish...
Source: EHP Research - November 3, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

New Blood: The Promise of Environmental Health Citizen Science Projects
PDF Version (4.5 MB) About This Article About This Article Supplemental Material Published: 2 November 2017 Note to readers with disabilities: EHP strives to ensure that all journal content is accessible to all readers. However, some figures and Supplemental Material published in EHP articles may not conform to 508 standards due to the complexity of the information being presented. If you need assistance accessing journal content, please contact ehponline@niehs.nih.gov. Our staff will work with you to assess and meet your accessibility needs within 3 working days. Published: 2 November 2017...
Source: EHP Research - November 2, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Focus Source Type: research

New Blood: The Promise of Environmental Health Citizen Science Projects
PDF Version (4.5 MB) About This Article Published: 2 November 2017 Note to readers with disabilities: EHP strives to ensure that all journal content is accessible to all readers. However, some figures and Supplemental Material published in EHP articles may not conform to 508 standards due to the complexity of the information being presented. If you need assistance accessing journal content, please contact ehponline@niehs.nih.gov. Our staff will work with you to assess and meet your accessibility needs within 3 working days.  Mónica Ramírez-Andreotta sat on a folding chai...
Source: EHP Research - November 2, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Focus Source Type: research

Erratum: “Urinary Concentrations of Organophosphate Flame Retardant Metabolites and Pregnancy Outcomes among Women Undergoing in Vitro Fertilization”
PDF Version (233 KB) About This Article Received: 1 September 2017 Accepted: 9 September 2017 Published: 1 November 2017 Address correspondence to C. Carignan, Department of Environmental Health, Building 1, 14th Floor, 665 Huntington Avenue, Boston, MA 02115 USA. Phone: (617) 432-4572. Email: carignan@hsph.harvard.edu Note to readers with disabilities: EHP strives to ensure that all journal content is accessible to all readers. However, some figures and Supplemental Material published in EHP articles may not conform to 508 standards due to the complexity of the information being presented. If...
Source: EHP Research - November 1, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Erratum Source Type: research

Unwell: The Public Health Implications of Unregulated Drinking Water
PDF Version (1.5 MB) About This Article Published: 1 November 2017 Note to readers with disabilities: EHP strives to ensure that all journal content is accessible to all readers. However, some figures and Supplemental Material published in EHP articles may not conform to 508 standards due to the complexity of the information being presented. If you need assistance accessing journal content, please contact ehponline@niehs.nih.gov. Our staff will work with you to assess and meet your accessibility needs within 3 working days.  Related EHP Article Strategies to Improve Private-Well Water...
Source: EHP Research - November 1, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Science Selection Source Type: research

An Investigation of the Single and Combined Phthalate Metabolite Effects on Human Chorionic Gonadotropin Expression in Placental Cells
Conclusions: Concentrations of MnBP, MBzP and MEHP similar to those found in the urine of pregnant women consistently altered hCG and PPARγ expression in primary placental cells. These findings provide evidence for the molecular basis by which phthalates may alter placental function, and they provide a preliminary mechanistic hypothesis for opposite responses by sex. https://doi.org/10.1289/EHP1539 Received: 23 December 2016 Revised: 6 September 2017 Accepted: 18 September 2017 Published: 31 October 2017 Address correspondence to J.J. Adibi, 130 Desoto Street, Parran Hall 5132, Pittsburgh, PA 15261 USA. Telephone...
Source: EHP Research - October 31, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

Air Conditioning Use and Heat-Related Deaths: How a Natural Disaster Presented a Unique Research Opportunity
PDF Version (1.1 MB) About This Article Published: 30 October 2017 Note to readers with disabilities: EHP strives to ensure that all journal content is accessible to all readers. However, some figures and Supplemental Material published in EHP articles may not conform to 508 standards due to the complexity of the information being presented. If you need assistance accessing journal content, please contact ehponline@niehs.nih.gov. Our staff will work with you to assess and meet your accessibility needs within 3 working days.  The aftermath of the Great East Japan Earthquake and resulting ts...
Source: EHP Research - October 30, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Science Selection Source Type: research

Longer-Term Impact of High and Low Temperature on Mortality: An International Study to Clarify Length of Mortality Displacement
Conclusions: These results provide strong evidence that most deaths associated in daily analyses with heat and cold are displaced by at least 1 y. https://doi.org/10.1289/EHP1756 Received: 10 February 2017 Revised: 25 September 2017 Accepted: 26 September 2017 Published: 27 October 2017 Address correspondence to B. Armstrong, London School of Hygiene and Tropical Medicine, Keppel St., London WC1E 7HT, UK. Telephone: 0044 (0)20 79272232. Email: ben.armstrong@lshtm.ac.uk Supplemental Material is available online (https://doi.org/10.1289/EHP1756). The authors declare they have no actual or potential competing financial in...
Source: EHP Research - October 28, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

Examining Lead Exposures in California through State-Issued Health Alerts for Food Contamination and an Exposure-Based Candy Testing Program
Conclusions Based on these observations, lead-contaminated candies represent an important contribution to lead exposures in California. The fact that a large number of unique products were identified among the contaminated candies presents an ongoing challenge for exposure-based testing programs, as does the large number of candies tested for which no lead was detected. After legislation was passed requiring more widespread testing of candies for lead, many imported candies were identified as containing lead, suggesting that imported candy might be considered a public health risk for lead poisoning in California. However, ...
Source: EHP Research - October 26, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Brief Communication Source Type: research

Associations between Ambient Fine Particulate Oxidative Potential and Cardiorespiratory Emergency Department Visits
Conclusions: Lag 0–2 OPDTT was associated with ED visits for multiple cardiorespiratory outcomes, providing support for the utility of OPDTT as a measure of fine particle toxicity. https://doi.org/10.1289/EHP1545 Received: 23 December 2016 Revised: 4 August 2017 Accepted: 12 August 2017 Published: 26 October 2017 Please address correspondence to J.Y. Abrams, Centers for Disease Control and Prevention, NCEZID/DHCPP, 1600 Clifton Rd. NE, CDC Mailstop A30, Atlanta, GA 30333 USA. Telephone: (404) 639-5121. Email: jabrams@cdc.gov Supplemental Material is available online (https://doi.org/10.1289/EHP1545). The authors ...
Source: EHP Research - October 26, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

Online Serum PFOA Calculator for Adults
Conclusions Pharmacokinetic models are useful for understanding the relationship between exposure and measured biomarkers and are increasingly being applied in environmental health research and regulation. However, these models are complex enough to be a potential barrier for some researchers, exposed individuals, and other stakeholders. Online calculators using appropriate literature-based default parameters can facilitate research translation for such models. Acknowledgments The author thanks J. Wagner of the Bucks County Courier Times for asking thoughtful questions that inspired the calculator. References ATSDR (Agenc...
Source: EHP Research - October 24, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Brief Communication Source Type: research

After the Screening: What Happens Next for Children with Elevated Blood Lead?
PDF Version (2 MB) About This Article About This Article Received: 06 July 2017 Accepted: 06 July 2017 Published: 24 October 2017 Note to readers with disabilities: EHP strives to ensure that all journal content is accessible to all readers. However, some figures and Supplemental Material published in EHP articles may not conform to 508 standards due to the complexity of the information being presented. If you need assistance accessing journal content, please contact ehponline@niehs.nih.gov. Our staff will work with you to assess and meet your accessibility needs within 3 working days. Re...
Source: EHP Research - October 24, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Focus Source Type: research

Folic Acid and ASDs: A Preventive Measure against Potential Effects of Pesticide Exposures?
PDF Version (176 KB) About This Article Published: 23 October 2017 Note to readers with disabilities: EHP strives to ensure that all journal content is accessible to all readers. However, some figures and Supplemental Material published in EHP articles may not conform to 508 standards due to the complexity of the information being presented. If you need assistance accessing journal content, please contact ehponline@niehs.nih.gov. Our staff will work with you to assess and meet your accessibility needs within 3 working days. Related EHP Article Combined Prenatal Pesticide Exposu...
Source: EHP Research - October 23, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Science Selection Source Type: research

Erratum: “An Integrated Experimental Design for the Assessment of Multiple Toxicological End Points in Rat Bioassays”
PDF Version (52 KB) About This Article Received: 21 September 2017 Accepted: 22 September 2017 Published: 23 October 2017 Address correspondence to F. Belpoggi, Cesare Maltoni Cancer Research Center, Ramazzini Institute, Via Saliceto, 3, 40010 Bentivoglio, Bologna, Italy. Telephone: 39 051 6640460. Email: belpoggif@ramazzini.it Note to readers with disabilities: EHP strives to ensure that all journal content is accessible to all readers. However, some figures and Supplemental Material published in EHP articles may not conform to 508 standards due to the complexity of the information being presen...
Source: EHP Research - October 23, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Erratum Source Type: research

Peas in a Pod? The Similarities between UFPs and Nanoparticles Yield Research Opportunities
PDF Version (514 KB) About This Article Published: 20 October 2017 Note to readers with disabilities: EHP strives to ensure that all journal content is accessible to all readers. However, some figures and Supplemental Material published in EHP articles may not conform to 508 standards due to the complexity of the information being presented. If you need assistance accessing journal content, please contact ehponline@niehs.nih.gov. Our staff will work with you to assess and meet your accessibility needs within 3 working days. Related EHP Article Nanomaterials Versus Ambient Ultra...
Source: EHP Research - October 21, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Science Selection Source Type: research

Plasma Metal Concentrations and Incident Coronary Heart Disease in Chinese Adults: The Dongfeng-Tongji Cohort
Conclusions: Our study suggested that incident CHD was positively associated with plasma levels of titanium and arsenic, and inversely associated with selenium. Additional research is needed to confirm these findings in other populations. https://doi.org/10.1289/EHP1521 Received: 22 December 2016 Revised: 17 September 2017 Accepted: 19 September 2017 Published: 19 October 2017 Address correspondence to T. Wu, or A. Pan, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, 13 Hongkong Rd., Wuhan 430030, Hubei, China. Telephone: +86-27-83692347. Email: wut@mails.tjmu.edu.cn or p...
Source: EHP Research - October 20, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

Warm, Cozy Woodstoves .  . .  and the PM They Produce: Home Interventions Show Mixed Results in Protecting Children with Asthma
PDF Version (578 KB) About This Article Published: 17 October 2017 Note to readers with disabilities: EHP strives to ensure that all journal content is accessible to all readers. However, some figures and Supplemental Material published in EHP articles may not conform to 508 standards due to the complexity of the information being presented. If you need assistance accessing journal content, please contact ehponline@niehs.nih.gov. Our staff will work with you to assess and meet your accessibility needs within 3 working days. Related EHP Article Randomized Trial of Interventions ...
Source: EHP Research - October 17, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Science Selection Source Type: research

Variation in DNA-Damage Responses to an Inhalational Carcinogen (1,3-Butadiene) in Relation to Strain-Specific Differences in Chromatin Accessibility and Gene Transcription Profiles in C57BL/6J and CAST/EiJ Mice
Conclusions: These results suggest that strain-specific changes in chromatin and transcription in response to chemical exposure lead to a “compensation” for underlying genetic-driven interindividual differences in the baseline chromatin and transcriptional state. This work represents an example of how chemical and environmental exposures can be evaluated to better understand gene-by-environment interactions, and it demonstrates the important role of chromatin response in transcriptomic changes and, potentially, in deleterious effects of exposure. https://doi.org/10.1289/EHP1937 Received: 21 March 2017 Revis...
Source: EHP Research - October 17, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

Small-Scale Food Animal Production and Antimicrobial Resistance: Mountain, Molehill, or Something in-between?
Author Affiliations open 1Public Health Institute, Oakland, California, USA 2Department of Epidemiology, University of Michigan, Ann Arbor, Michigan, USA 3Instituto de Microbiologia, Colegio de Ciencias Biologicas y Ambientales, Universidad San Francisco de Quito, Quito, Ecuador 4Department of Epidemiology and Biostatistics, Michigan State University, East Lansing, Michigan, USA 5Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, Michigan, USA 6Department of Veterinary and Biomedical Sciences, University of Minnesota, St. Paul, Minnesota, USA PDF Version (176 KB) Abstract ...
Source: EHP Research - October 16, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Brief Communication Source Type: research

Long-Term Exposure to Ambient Air Pollution and Incidence of Postmenopausal Breast Cancer in 15 European Cohorts within the ESCAPE Project
Conclusions: We found suggestive evidence of an association between ambient air pollution and incidence of postmenopausal breast cancer in European women. https://doi.org/10.1289/EHP1742 Received: 9 February 2017 Revised: 4 August 2017 Accepted: 12 August 2017 Published: 13 October 2017 Address correspondence to Z.J. Andersen, Centre for Epidemiology and Screening, Department of Public Health, University of Copenhagen, Øster Farimagsgade 5, 1014 København K, Denmark; Telephone: 45 20740462; Email: zorana.andersen@sund.ku.dk Supplemental Material is available online (https://doi.org/10.1289/EHP1742). The a...
Source: EHP Research - October 13, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

Nanomaterials Versus Ambient Ultrafine Particles: An Opportunity to Exchange Toxicology Knowledge
Author Affiliations open 1Institute of Biological Chemistry, Biophysics and Bioengineering, Heriot-Watt University, Edinburgh, Scotland, UK 2Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, Scotland, UK 3Adolphe Merkle Institute, University of Fribourg, Fribourg, Switzerland 4Swansea University Medical School, Swansea, Wales, UK 5University of Rochester Medical Center, Rochester, New York 6Department of Public Health, University of Copenhagen, Copenhagen, Denmark 7IUF Leibniz-Institut für Umweltmedizinische Forschung, Düsseldorf, Germany 8National Research Centre for the Working Environment...
Source: EHP Research - October 10, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Review Source Type: research

Environmental Suitability of Vibrio Infections in a Warming Climate: An Early Warning System
Conclusions: This platform can serve as an early warning system as the risk of further Vibrio infections increases in the 21st century due to climate change. https://doi.org/10.1289/EHP2198 Received: 17 May 2017 Revised: 12 August 2017 Accepted: 14 August 2017 Published: 10 October 2017 Address correspondence to J.C. Semenza, European Centre for Disease Prevention and Control (ECDC), Granits väg 8, 171 65 Solna, Sweden. Telephone: 46 (0)8 58 60 1217. Email: Jan.Semenza@ecdc.europa.eu Supplemental Material is available online (https://doi.org/10.1289/EHP2198). The authors declare they have no actual or potential co...
Source: EHP Research - October 10, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

Feeling the Heat: The Health Effects of Hot Days Vary across the Globe
PDF Version (718 KB) About This Article Published: 05 October 2017 Note to readers with disabilities: EHP strives to ensure that all journal content is accessible to all readers. However, some figures and Supplemental Material published in EHP articles may not conform to 508 standards due to the complexity of the information being presented. If you need assistance accessing journal content, please contact ehponline@niehs.nih.gov. Our staff will work with you to assess and meet your accessibility needs within 3 working days. Related EHP Article Heat Wave and Mortality: A Multico...
Source: EHP Research - October 5, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Science Selection Source Type: research

Systematic Review and Meta-Analysis of Early-Life Exposure to Bisphenol A and Obesity-Related Outcomes in Rodents
Conclusions: Findings from our systematic review suggest that early-life exposure to BPA may increase adiposity and circulating lipid levels in rodents. https://doi.org/10.1289/EHP1233 Received: 21 October 2016 Revised: 27 June 2017 Accepted: 05 July 2017 Published: 05 October 2017 Address correspondence to J. Legler, Institute for Environment, Health and Societies, Brunel University London, Uxbridge, UK. Telephone: 44-1895-266789. Email: juliette.legler@brunel.ac.uk Supplemental Material is available online (https://doi.org/10.1289/EHP1233). The authors declare they have no actual or potential competing financial in...
Source: EHP Research - October 5, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Review Source Type: research

Low Prenatal Exposures to Fluoride: Are There Neurotoxic Risks for Children?
PDF Version (532 KB) About This Article Published: 04 October 2017 Note to readers with disabilities: EHP strives to ensure that all journal content is accessible to all readers. However, some figures and Supplemental Material published in EHP articles may not conform to 508 standards due to the complexity of the information being presented. If you need assistance accessing journal content, please contact ehponline@niehs.nih.gov. Our staff will work with you to assess and meet your accessibility needs within 3 working days. Related EHP Article Prenatal Fluoride Exposure and Cog...
Source: EHP Research - October 4, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Science Selection Source Type: research

Decomposition Analysis of Black –White Disparities in Birth Outcomes: The Relative Contribution of Air Pollution and Social Factors in California
Conclusions: Our results suggest that, although the role of individual and neighborhood factors remains prevailing in explaining black–white differences in birth outcomes, the individual contribution of PM2.5 is comparable in magnitude to any single individual- or neighborhood-level factor. https://doi.org/10.1289/EHP490 Received: 10 May 2016 Revised: 16 December 2016 Accepted: 03 January 2017 Published: 04 October 2017 Address correspondence to T. Benmarhnia, Department of Family Medicine and Public Health, and Scripps Institution of Oceanography, University of California, San Diego, 9500 Gilman Drive, La Joll...
Source: EHP Research - October 4, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

Reconciling Sex-Related Bias: An Alternative Method for Data Analysis
PDF Version (605 KB) About This Article Published: 03 October 2017 Note to readers with disabilities: EHP strives to ensure that all journal content is accessible to all readers. However, some figures and Supplemental Material published in EHP articles may not conform to 508 standards due to the complexity of the information being presented. If you need assistance accessing journal content, please contact ehponline@niehs.nih.gov. Our staff will work with you to assess and meet your accessibility needs within 3 working days. During development, hormones guide the processes that underlie th...
Source: EHP Research - October 3, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Science Selection Source Type: research

Prenatal and Postnatal PCB-153 and p,p ′-DDE Exposures and Behavior Scores at 5–9 Years of Age among Children in Greenland and Ukraine
Conclusion: Prenatal and early postnatal exposures to p,p′-DDE and PCB-153 were associated with a higher prevalence of abnormal scores for conduct and hyperactivity at 5–9 y of age in our study population. These findings provide further support for the importance of minimizing organochlorine exposures to young children and to women of childbearing age. https://doi.org/10.1289/EHP553 Received: 24 May 2016 Revised: 29 August 2017 Accepted: 29 August 2017 Published: 03 October 2017 Address correspondence to A.H. Rosenquist, Department of Clinical Epidemiology, Olof Palmes Allé 43-45, 8200 Aarhus N, De...
Source: EHP Research - October 3, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

Prenatal and Postnatal PCB-153 and p,p ’ -DDE Exposures and Behavior Scores at 5 –9 Years of Age among Children in Greenland and Ukraine
Conclusion: Prenatal and early postnatal exposures to p,p′-DDE and PCB-153 were associated with a higher prevalence of abnormal scores for conduct and hyperactivity at 5–9 y of age in our study population. These findings provide further support for the importance of minimizing organochlorine exposures to young children and to women of childbearing age. https://doi.org/10.1289/EHP553 Received: 24 May 2016 Revised: 29 August 2017 Accepted: 29 August 2017 Published: 03 October 2017 Address correspondence to A.H. Rosenquist, Department of Clinical Epidemiology, Olof Palmes Allé 43-45, 8200 Aarhus N, De...
Source: EHP Research - October 3, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

Plasma Concentrations of Per- and Polyfluoroalkyl Substances at Baseline and Associations with Glycemic Indicators and Diabetes Incidence among High-Risk Adults in the Diabetes Prevention Program Trial
Conclusions: At baseline, several PFAS were cross-sectionally associated with small differences in markers of insulin secretion and β-cell function. However, there was limited evidence suggesting that PFAS concentrations are associated with diabetes incidence or changes in glycemic indicators during the follow-up period. https://doi.org/10.1289/EHP1612 Received: 12 January 2017 Revised: 03 August 2017 Accepted: 04 August 2017 Published: 02 October 2017 Address correspondence to E. Oken, Obesity Prevention Program, Harvard Medical School and Harvard Pilgrim HealthCare Institute, Dept. of Population Medicine, 401 ...
Source: EHP Research - October 3, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

Traffic-Related Air Pollution and All-Cause Mortality during Tuberculosis Treatment in California
Conclusions: Residential proximity to road traffic volumes and traffic density were associated with increased all-cause mortality in patients undergoing treatment for active tuberculosis even after adjusting for multiple demographic, socioeconomic, and clinical factors, suggesting that TB patients are susceptible to the adverse health effects of traffic-related air pollution. https://doi.org/10.1289/EHP1699 Received: 31 January 2017 Revised: 18 August 2017 Accepted: 23 August 2017 Published: 29 September 2017 Address correspondence to R.J. Blount, Divisions of Pulmonary and Critical Care Medicine and Pediatric Pulmon...
Source: EHP Research - September 29, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

Residential Air Pollution and Associations with Wheeze and Shortness of Breath in Adults: A Combined Analysis of Cross-Sectional Data from Two Large European Cohorts
Author Affiliations open 1Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada 2Swiss Tropical and Public Health Institute, Basel, Switzerland 3University of Basel, Basel, Switzerland 4Institute for Risk Assessment Sciences, Utrecht University, Utrecht, Netherlands 5MRC-PHE Centre for Environment and Health, Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK 6National Human Genome Research Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, USA 7University Medical Center Groningen, Gron...
Source: EHP Research - September 29, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

Effects of Orally Ingested Arsenic on Respiratory Epithelial Permeability to Bacteria and Small Molecules in Mice
Conclusions: Peroral arsenic has little effect on local airway immune responses to bacteria but compromises respiratory epithelial barrier integrity, increasing systemic translocation of inhaled pathogens and small molecules. https://doi.org/10.1289/EHP1878 Received: 09 March 2017 Revised: 14 August 2017 Accepted: 16 August 2017 Published: 28 September 2017 Address correspondence to M.B. Fessler, National Institute of Environmental Health Sciences, 111 T.W. Alexander Dr., P.O. Box 12233, Maildrop D2-01, Research Triangle Park, NC 27709 USA. Telephone: (919) 541-3701. Email: fesslerm@niehs.nih.gov *Current address: UN...
Source: EHP Research - September 28, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

Long-Term Air Pollution Exposure and Amyotrophic Lateral Sclerosis in Netherlands: A Population-based Case –control Study
Author Affiliations open 1Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, Netherlands 2Environmental Epidemiology Division, Institute for Risk Assessment Sciences, Utrecht University, Utrecht, Netherlands 3Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, Netherlands 4Department of Neurology, Amsterdam Medical Center, University of Amsterdam, Amsterdam, Netherlands 5Department of Neurology, Donders Institute for Brain, Cognition and Behavior, Center for Neuroscience, Radboud University Nijmegen Medical Center, Nijmegen, Netherla...
Source: EHP Research - September 27, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

Sex- and Dose-Specific Effects of Maternal Bisphenol A Exposure on Pancreatic Islets of First- and Second-Generation Adult Mice Offspring
Conclusion: These findings demonstrate that maternal BPA exposure has dose- and sex-specific effects on pancreatic islets of adult F1 and F2 mice offspring. The transmission of these changes across multiple generations may involve either mitochondrial dysfunction and/or epigenetic modifications. https://doi.org/10.1289/EHP1674 Received: 25 January 2017 Revised: 26 July 2017 Accepted: 26 July 2017 Published: 27 September 2017 Please address correspondence to R.A. Simmons, Center for Research on Reproduction and Women’s Health, Perelman School of Medicine, University of Pennsylvania, 1308 BRB II/III, 421 Curie Bl...
Source: EHP Research - September 27, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

Long-Term Exposure to Road Traffic Noise and Nitrogen Dioxide and Risk of Heart Failure: A Cohort Study
Conclusions: Long-term exposure to NO2 and road traffic noise was associated with higher risk of heart failure, mainly among men, in both single- and two-pollutant models. High exposure to both pollutants was associated with highest risk. https://doi.org/10.1289/EHP1272 Received: 25 October 2016 Revised: 09 August 2017 Accepted: 09 August 2017 Published: 26 September 2017 Address correspondence to M. Sørensen. Diet, Genes and Environment, Danish Cancer Society, Strandboulevarden 49, 2100 Copenhagen, Denmark. Telephone: +45 35257626. Email: mettes@cancer.dk Supplemental Material is available online (https://doi...
Source: EHP Research - September 26, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

Serum Polybrominated Biphenyls (PBBs) and Polychlorinated Biphenyls (PCBs) and Thyroid Function among Michigan Adults Several Decades after the 1973 –1974 PBB Contamination of Livestock Feed
Conclusions: We found some evidence to support associations of PBBs and PCBs with thyroid disease and thyroid hormone levels. https://doi.org/10.1289/EHP1302 Received: 28 October 2016 Revised: 31 July 2017 Accepted: 01 August 2017 Published: 26 September 2017 Address correspondence to M.H. Jacobson, 1518 Clifton Rd. NE, CNR 3rd Floor, Atlanta, GA 30322 USA. Telephone: 914-589-3926. Email: mhymanjacobson@emory.edu Supplemental Material is available online (https://doi.org/10.1289/EHP1302). The authors declare they have no actual or potential competing financial interests. Note to readers with disabilities: EHP&nb...
Source: EHP Research - September 26, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

Inequality of Noise Exposures: A Portrait of the United States
PDF Version (483 KB) About This Article Published: 25 September 2017 Note to readers with disabilities: EHP strives to ensure that all journal content is accessible to all readers. However, some figures and Supplemental Material published in EHP articles may not conform to 508 standards due to the complexity of the information being presented. If you need assistance accessing journal content, please contact ehponline@niehs.nih.gov. Our staff will work with you to assess and meet your accessibility needs within 3 working days. Related EHP Article Race/Ethnicity, Socioeconomic St...
Source: EHP Research - September 25, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Science Selection Source Type: research

Conducting Science in Disasters: Recommendations from the NIEHS Working Group for Special IRB Considerations in the Review of Disaster Related Research
Conclusion The burgeoning field of disaster research has placed greater demands on IRBs to ensure that the welfare and rights of human research subjects are protected during disaster studies. The review of disaster research protocols requires new tools and training for IRBs to assure the protection of disaster survivors from research-related harms. These recommendations are currently being evaluated and prioritized by NIH officials to determine the process for moving forward with implementation. Although disaster research conducted during response may be challenging, IRBs can play useful roles in achieving careful, balance...
Source: EHP Research - September 25, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Brief Communication Source Type: research

From Ambient to Personal Temperature: Capturing the Experience of Heat Exposure
PDF Version (831 KB) About This Article Published: 22 September 2017 Note to readers with disabilities: EHP strives to ensure that all journal content is accessible to all readers. However, some figures and Supplemental Material published in EHP articles may not conform to 508 standards due to the complexity of the information being presented. If you need assistance accessing journal content, please contact ehponline@niehs.nih.gov. Our staff will work with you to assess and meet your accessibility needs within 3 working days. Heat exposure can have a wide range of adverse effects on the h...
Source: EHP Research - September 22, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Science Selection Source Type: research

Estimated Deficiencies Resulting from Reduced Protein Content of Staple Foods: Taking the Cream out of the Crop?
PDF Version (619 KB) About This Article Published: 22 September 2017 Note to readers with disabilities: EHP strives to ensure that all journal content is accessible to all readers. However, some figures and Supplemental Material published in EHP articles may not conform to 508 standards due to the complexity of the information being presented. If you need assistance accessing journal content, please contact ehponline@niehs.nih.gov. Our staff will work with you to assess and meet your accessibility needs within 3 working days. Projected changes in climate are expected to play a complicated...
Source: EHP Research - September 22, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Science Selection Source Type: research

Portable Functional Neuroimaging as an Environmental Epidemiology Tool: A How-To Guide for the Use of fNIRS in Field Studies
Conclusion The overarching goal of this paper is to demonstrate the feasibility of employing functional neuroimaging in epidemiological studies regardless of the location or the conditions in which the study is taking place. Critically, this is now possible using readily available, portable fNIRS neuroimaging devices to assess neurobehavioral functioning across multiple domains. Most importantly, in our study, the addition of the fNIRS assessment did not interfere with the goals of the ongoing epidemiological study and was seamlessly integrated into daily operations. This paper provides a set of general guidelines that epi...
Source: EHP Research - September 21, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Brief Communication Source Type: research

Regulation of Chromatin Assembly and Cell Transformation by Formaldehyde Exposure in Human Cells
Conclusions: We propose that the inhibition of chromatin assembly represents a novel mechanism of cell transformation induced by the environmental and occupational chemical carcinogen FA. https://doi.org/10.1289/EHP1275 Received: 25 October 2016 Revised: 19 May 2017 Accepted: 23 May 2017 Published: 21 September 2017 Address correspondence to C. Jin, Dept. of Environmental Medicine, New York University School of Medicine, 57 Old Forge Rd., Tuxedo Park, NY 10987 USA. Telephone: (845) 731-3602. Email: Chunyuan.jin@nyumc.org *Current affiliation: Medical School of Nanjing University, Nanjing, China. †Current affil...
Source: EHP Research - September 21, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research