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Corynebacterium, Kingella Abundance Tied to HNSCC Risk
No correlation for overall microbiome composition with risk of head and neck squamous cell carcinoma (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - January 12, 2018 Category: Cancer & Oncology Tags: Oncology, ENT, Pathology, Journal, Source Type: news

Certain factors may predict lung cancer patients' response to chemotherapy
(Wiley) In a retrospective analysis of 73 lung squamous cell carcinoma patients treated with the chemotherapy regimen of gemcitabine plus cisplatin, higher body mass index and younger age were linked with longer progression-free survival, the length of time that a patient lives with cancer but it does not get worse. Patients with better response to treatment and higher body mass index had longer overall survival in the Thoracic Cancer analysis. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - January 10, 2018 Category: Cancer & Oncology Source Type: news

5-FU Cream Reduces Surgery in High-Risk SCC Patients 5-FU Cream Reduces Surgery in High-Risk SCC Patients
Use of a topical 5-FU cream for patients with squamous cell carcinoma (SCC) reduces the need for surgery on their face and ears, although the chemopreventive effect wanes over time.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - January 8, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Hydrochlorothiazide May Up Basal, Squamous Cell Cancer Risk
Increased risk for basal cell carcinoma, squamous cell carcinoma, with dose - response relationship (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - January 6, 2018 Category: Cancer & Oncology Tags: Cardiology, Dermatology, Family Medicine, Internal Medicine, Oncology, Pharmacy, Journal, Source Type: news

Fluorouracil Tied to Reduced Surgery for Squamous Cell CA
Reduced risk of squamous cell carcinoma, but not basal cell carcinoma, for one year in at - risk veterans (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - January 5, 2018 Category: Cancer & Oncology Tags: Dermatology, Oncology, Pharmacy, Journal, Source Type: news

A Little Dab'll Do Ya to Prevent Squamous Cell Carcinoma (CME/CE)
(MedPage Today) -- But side effects weren't negligible (Source: MedPage Today Dermatology)
Source: MedPage Today Dermatology - January 4, 2018 Category: Dermatology Source Type: news

Predicting Prognosis in Submucosal Invasive Esophageal SCC Predicting Prognosis in Submucosal Invasive Esophageal SCC
This study sought to identify histopathological characteristics that could predict lymph node metastasis in submucosal invasive esophageal squamous cell carcinoma.American Journal of Clinical Pathology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 3, 2018 Category: Consumer Health News Tags: Hematology-Oncology Journal Article Source Type: news

In clinical trial, cream reduces squamous cell carcinoma risk
(Brown University) Results of a new randomized, double-blinded, controlled clinical trial in veterans showed a 75 percent reduction in the risk of needing surgery to treat a squamous cell carcinoma for a year after applying a skin cream for up to four weeks. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - January 3, 2018 Category: Cancer & Oncology Source Type: news

Atopic Dermatitis Associated With Higher Risk of Skin Cancer
Individuals with a history of atopic dermatitis have a higher risk of squamous cell carcinoma development (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - December 29, 2017 Category: Cancer & Oncology Tags: Dermatology, Family Medicine, Internal Medicine, Allergy, Nursing, Oncology, Pathology, Pediatrics, Journal, Source Type: news

Nanobiotix ’s nanoparticle-immunotherapy trial wins FDA approval
Nanobiotix (EMA:NANO) said today that the FDA has approved its IND application for a cancer trial combining its radiotherapy-activated nanoparticle tech with an anti-PD1 antibody. The Phase I/II trial is slated to evaluate the safety and efficacy of Nanobiotix’s NBTXR3 product administered with checkpoint inhibitors in three groups of patients with recurrent or metastatic head and neck squamous cell carcinoma or with metastatic non-small cell lung cancer. Get the full story at our sister site, Drug Delivery Business News. The post Nanobiotix’s nanoparticle-immunotherapy trial wins FDA approval appeare...
Source: Mass Device - December 26, 2017 Category: Medical Devices Authors: Sarah Faulkner Tags: Clinical Trials Drug-Device Combinations Food & Drug Administration (FDA) Oncology Pharmaceuticals Wall Street Beat nanobiotix Source Type: news

Gaining insight into the molecular mechanisms behind squamous cell cancer
(Kanazawa University) Researchers at Kanazawa University report in EMBO Reports a new molecular mechanisms regulating cellular fate of squamous cell carcinomas. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - December 19, 2017 Category: Biology Source Type: news

Researchers find possible markers for earlier diagnosis of aggressive tongue cancer
(Case Western Reserve University) Squamous cell carcinoma of the tongue, also known as oral tongue cancer, is an aggressive form of cancer that generally affects older people. in a new study published in Oncotarget, a team of researchers has found that bacterial diversity and richness, and fungal richness, are significantly reduced in tumor tissue compared to their matched non-tumor tissues. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 19, 2017 Category: International Medicine & Public Health Source Type: news

Frequent sun exposure may cue gene fusion found in skin cancer
(Kumamoto University) Researchers from Kumamoto University, Japan have determined that a particular fusion gene has a tendency to be found in cutaneous squamous cell carcinoma (cSCC) lesions on skin exposed frequently to the sun. The fusion gene is unique to cSCC and appears to be related to frequent sun exposure. It is believed that the work will open doors to a new form of personalized cSCC treatment. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - December 14, 2017 Category: Biology Source Type: news

Research Finds Popular Blood Pressure Drug Increases Skin Cancer Risk
This study shows a possible link between HCTZ and basal cell and squamous cell carcinomas of the skin. These are not melanomas, the deadliest form of skin cancer, but they both can pose serious health risks. This study shows an association between HCTZ and skin cancer, not proof that the medication actually causes cancer, but it’s link that needs to be studied further. In the meantime, continue to take your blood pressure medication and protect yourself from excessive sun exposure. (Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire)
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - December 6, 2017 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health Local News Syndicated Local Dr. Mallika Marshall Source Type: news

IL-33 and ST2 mediate FAK-dependent antitumor immune evasion through transcriptional networks
Focal adhesion kinase (FAK) mediates tumor cell–intrinsic behaviors that promote tumor growth and metastasis. We previously showed that FAK also induces the expression of inflammatory genes that inhibit antitumor immunity in the microenvironment. We identified a crucial, previously unknown role for the dual-function cytokine interleukin-33 (IL-33) in FAK-dependent immune evasion. In murine squamous cell carcinoma (SCC) cells, specifically nuclear FAK enhanced the expression of the genes encoding IL-33, the chemokine CCL5, and the soluble, secreted form of the IL-33 receptor, called soluble ST2 (sST2). The abundance o...
Source: Signal Transduction Knowledge Environment - December 5, 2017 Category: Science Authors: Serrels, B., McGivern, N., Canel, M., Byron, A., Johnson, S. C., McSorley, H. J., Quinn, N., Taggart, D., Von Kreigsheim, A., Anderton, S. M., Serrels, A., Frame, M. C. Tags: STKE Research Articles Source Type: news

Tobacco Smoking Associated with Poor Survival Following Head and Neck Cancer Diagnosis
Researchers found a statistically significant difference in median survival time between smokers and nonsmokers at diagnosis of head and neck squamous cell carcinoma. (Source: CancerNetwork)
Source: CancerNetwork - November 30, 2017 Category: Cancer & Oncology Authors: Bryant Furlow Tags: Head & Neck Cancer News Source Type: news

ECC 2015: GIOTRIF ® (afatinib) demonstrates superior survival compared to Tarceva® (erlotinib) for patients with previously treated advanced squamous cell carcinoma of the lung, independent of EGFR mutation status
ECC 2015: GIOTRIF ® (afatinib) demonstrates superior survival compared to Tarceva® (erlotinib) for patients with previously treated advanced squamous cell carcinoma of the lung, independent of EGFR mutation status (Source: Boehringer Ingelheim Corporate News)
Source: Boehringer Ingelheim Corporate News - November 27, 2017 Category: Research Source Type: news

Sentinel Node Biopsy for High-Risk Squamous Cell Carcinoma Sentinel Node Biopsy for High-Risk Squamous Cell Carcinoma
Reuters Health Information (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - November 22, 2017 Category: Pathology Tags: Hematology-Oncology News Source Type: news

Should Some Oropharyngeal Cancer Patients Skip Adjuvant Chemo, Radiation With TORS? Should Some Oropharyngeal Cancer Patients Skip Adjuvant Chemo, Radiation With TORS?
For patients with oropharyngeal squamous cell carcinoma (OPSCC) receiving transoral robotic surgery (TORS), adjuvant radiotherapy or chemoradiotherapy (CRT) should be avoided if possible, according to a long-term functional and quality-of-life (QOL) outcomes study.Reuters Health Information (Source: Medscape Radiology Headlines)
Source: Medscape Radiology Headlines - November 6, 2017 Category: Radiology Tags: Hematology-Oncology News Source Type: news

A squamous cell carcinoma that disproportionately affects men
Factors that drive lip squamous cell carcinomas in men. (Source: Dermatology Times)
Source: Dermatology Times - November 1, 2017 Category: Dermatology Source Type: news

Report: Doctor self-diagnoses cancer while testing Butterfly iQ ultrasound
A vascular surgeon was able to diagnose his own cancer while testing the Butterfly Network’s Butterfly iQ ultrasound-on-a-chip device, according to a report from USA Today. After experiencing some throat discomfort Dr. John Martin self-tested the device, designed to send images to and operate in conjunction with Apple (NSDQ:AAPL) iPhones, and found a mass that he thought looked cancerous, according to the report. The mass turned out to be squamous cell cancer which Martin has since received treatment for, including surgery and radiation therapy. “I felt something funny in my neck, connected the probe to my...
Source: Mass Device - October 30, 2017 Category: Medical Devices Authors: Fink Densford Tags: Imaging Oncology Apple butterflynetwork Source Type: news

Skin Cancer Melanoma Squamous Cell Basal Cell
Skin Cancer (Melanoma, Squamous Cell, Basal Cell Cancer) in Children (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - October 24, 2017 Category: General Medicine Source Type: news

New Guidelines a Boon for Skin Cancer Staging
(MedPage Today) -- AJCC-8 guide expands definition of T3 cutaneous squamous cell carcinoma (Source: MedPage Today Dermatology)
Source: MedPage Today Dermatology - October 15, 2017 Category: Dermatology Source Type: news

Your NEJM Group Today: Squamous Cell Carcinoma of the Mouth / Asthma Treatments Compared / California Family Medicine Opportunity (FREE)
By the Editors Take a look at today's offering from NEJM Group:NEJM Clinical Practice Center: Image in Clinical Medicine: A 54-year-old woman who regularly chewed … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - September 27, 2017 Category: Primary Care Source Type: news

Tailored Treatment for Head-and-Neck Cancer Mystery
Treatment TermsHead and Neck Cancer Overview Rob Vaughn found a lump on his neck that turned out to be cancer that had spread from somewhere else in his body. The trouble was, doctors couldn ’t find the original site of the cancer. That made his treatment decisions difficult -- until two Duke specialists offered him options, including the option for watchful waiting instead of extensive treatment. Hero Image20170914_robvaughn_neckcancer_083_herocrop.jpg Preview Image Content Blocks Header A Search for the Source of Cancer ContentVaughn, a Charlotte, NC, father of two, was 47 and in good health when he felt th...
Source: dukehealth.org: Duke Health News - September 15, 2017 Category: Consumer Health News Authors: mf205 at duke.edu Source Type: news

Regeneron and Sanofi receive FDA ’s breakthrough therapy status for CSCC treatment with cemiplimab
US-based Regeneron Pharmaceuticals and French company Sanofi have received breakthrough therapy designation status for cemiplimab (REGN2810) from the US Food and Drug Administration (FDA) to treat cutaneous squamous cell carcinoma (CSCC). (Source: Pharmaceutical Technology)
Source: Pharmaceutical Technology - September 10, 2017 Category: Pharmaceuticals Source Type: news

Sanofi and Regeneron announce that cemiplimab (REGN2810) has received FDA Breakthrough Therapy designation for advanced cutaneous squamous cell carcinoma
Sanofi and Regeneron Pharmaceuticals, Inc. today announced that the U.S. Food and Drug Administration (FDA) has granted Breakthrough Therapy designation status to cemiplimab (REGN2810) for the treatment of adults with metastatic cutaneous squamous cell carcinoma (CSCC) and adults with locally advanced and unresectable CSCC, the second deadliest skin cancer after melanoma[1], [2]. Cemiplimab is an investigational human, monoclonal antibody targeting PD-1. (Source: World Pharma News)
Source: World Pharma News - September 8, 2017 Category: Pharmaceuticals Tags: Featured Sanofi Business and Industry Source Type: news

Regeneron and Sanofi Announce Cemiplimab (REGN2810) Has Received FDA Breakthrough Therapy Designation for Advanced Cutaneous Squamous Cell Carcinoma
TARRYTOWN, N.Y. and PARIS, Sept. 8, 2017 -- (Healthcare Sales & Marketing Network) -- Regeneron Pharmaceuticals, Inc. (NASDAQ: REGN) and Sanofi today announced that the U.S. Food and Drug Administration (FDA) has granted Breakthrough Therapy designation s... Biopharmaceuticals, Oncology Regeneron Pharmaceuticals, Sanofi, cemiplimab, cutaneous squamous cell carcinoma (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - September 8, 2017 Category: Pharmaceuticals Source Type: news

Gliknik commences dosing in Phase II oral cavity cancer trial
US-based biopharmaceutical firm Gliknik has commenced patient dosing in a Phase II clinical trial of immunomodulatory therapeutic biropepimut-S (GL-0817) to prevent recurrence of oral cavity squamous cell cancer. (Source: Drug Development Technology)
Source: Drug Development Technology - August 29, 2017 Category: Pharmaceuticals Source Type: news

Newly developed nomograms provide accurate predictions for patients with oropharyngeal cancer
(NRG Oncology) NRG Oncology researchers recently developed and validated a nomogram that can predict 2-year and 5-year overall survival (OS) and progression-free survival (PFS) for patients with local-regionally advanced oropharyngeal squamous cell carcinoma (OPSCC) treated primarily with radiation-based therapy. This nomogram was developed with data from clinical trials NRG Oncology/RTOG 0129 and 0522. Results were published online in the Journal of Clinical Oncology on Aug. 4, 2017. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - August 21, 2017 Category: Cancer & Oncology Source Type: news

Nodal Stage Migration in Anal Cancer May Misclassify True Disease Stage
The rate of lymph node positivity in patients with squamous cell carcinoma of the anus may be overestimated, potentially leading to the overtreatment of patients with chemoradiotherapy. (Source: CancerNetwork)
Source: CancerNetwork - August 18, 2017 Category: Cancer & Oncology Authors: Leah Lawrence Tags: Gastrointestinal Cancer News Source Type: news

Anal Cancer More Deadly in Black Men
Significant racial and gender-based disparities exist in outcomes among patients with squamous cell carcinoma of the anus, with black men having the lowest survival rates, according to a new study. (Source: CancerNetwork)
Source: CancerNetwork - August 18, 2017 Category: Cancer & Oncology Authors: Mark L. Fuerst Tags: Gastrointestinal Cancer News Source Type: news

NICE recommends Merck ’s erbitux to treat R/M SCCHN in oral cavity
The UK National Institute for Health and Care Excellence (NICE) has recommended the routine use of Merck ’s erbitux (cetuximab), in combination with platinum-based chemotherapy, to treat recurrent and / or metastatic (R/M) squamous cell carcinoma of t… (Source: Pharmaceutical Technology)
Source: Pharmaceutical Technology - August 9, 2017 Category: Pharmaceuticals Source Type: news

Alcohol linked to an increased risk of skin cancer
Conclusion These findings should be interpreted with care before concluding that an alcoholic drink per day increases your risk of skin cancer. There are several important cautions: These are only observational studies. It wouldn't be possible to randomise people to different alcohol intake and follow them to look at cancer development. And with observational studies, many other health, sociodemographic and lifestyle factors may be influencing the link between alcohol intake and cancer development. The studies differed considerably in terms of the influencing factors they took account of, with some adjusting for various ...
Source: NHS News Feed - August 7, 2017 Category: Consumer Health News Tags: Cancer Source Type: news

Knoxville woman records her fight with deadly skin cancer
Marisha Dotson, 28, from Knoxville in Tennessee, has lost her nose, parts of her jaw and eight teeth during her battle with squamous cell carcinoma. (Source: the Mail online | Health)
Source: the Mail online | Health - August 4, 2017 Category: Consumer Health News Source Type: news

Orphan, 28, documents her battle with deadly skin cancer
Marisha Dotson, 28, from Knoxville in Tennessee, has lost her nose, parts of her jaw and eight teeth during her battle with squamous cell carcinoma. (Source: the Mail online | Health)
Source: the Mail online | Health - August 4, 2017 Category: Consumer Health News Source Type: news

Medical News Today: Every 10 grams of alcohol per day may raise skin cancer risk
The risk of basal and squamous cell carcinomas may increase with every 10 grams of alcohol consumed each day, new research suggests. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - August 2, 2017 Category: Consumer Health News Tags: Alcohol / Addiction / Illegal Drugs Source Type: news

Alcohol increases the risk of skin cancer by up to 11%
Researchers from Brown University found that for every 10 grams of alcohol a day, a person's risk of basal cell carcinoma increases by 7 percent and cutaneous squamous cell carcinoma by 11 percent. (Source: the Mail online | Health)
Source: the Mail online | Health - August 1, 2017 Category: Consumer Health News Source Type: news

Adherence to Quality Metrics Could Improve Head and Neck Cancer Survival
Adherence to each of five quality metrics for head and neck squamous cell carcinoma was associated with a reduced risk for death. (Source: CancerNetwork)
Source: CancerNetwork - July 31, 2017 Category: Cancer & Oncology Authors: Leah Lawrence Tags: Head & Neck Cancer News Source Type: news

Alcohol intake may increase risk of nonmelanoma skin cancers
(Wiley) In a recent analysis of published studies, higher alcohol intake was linked with an increased risk of both basal cell carcinoma and cutaneous squamous cell carcinoma, which are nonmelanoma skin cancers. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - July 31, 2017 Category: International Medicine & Public Health Source Type: news

Melanoma isn't the only serious skin cancer
A type of skin cancer called squamous cell carcinoma (SCC) is increasingly common in the United States. (Source: Health News - UPI.com)
Source: Health News - UPI.com - July 28, 2017 Category: Consumer Health News Source Type: news

Melanoma Isn't the Only Serious Skin Cancer
Squamous cell carcinoma is far more common and also dangerous if untreated, dermatologist says (Source: Cancercompass News: Other Cancer)
Source: Cancercompass News: Other Cancer - July 28, 2017 Category: Cancer & Oncology Source Type: news

Melanoma Isn't the Only Serious Skin Cancer
Squamous cell carcinoma is far more common and also dangerous if untreated, dermatologist says (Source: WebMD Health)
Source: WebMD Health - July 27, 2017 Category: Consumer Health News Source Type: news

Melanoma Isn ’ t the Only Serious Skin Cancer
Squamous cell carcinoma is far more common and also dangerous if untreated, dermatologist says (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - July 27, 2017 Category: Cancer & Oncology Tags: Dermatology, Oncology, News, Source Type: news

Melanoma Isn't the Only Serious Skin Cancer
THURSDAY, July 27, 2017 -- A type of skin cancer called squamous cell carcinoma (SCC) is increasingly common in the United States, so people need to be alert for signs of the disease, an expert says. About 700,000 new cases of this skin cancer are... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - July 27, 2017 Category: General Medicine Source Type: news

Increased Node Dissection Improved Survival in Node-Negative Oral Cavity SCC
Higher nodal yield during definitive surgery for clinically node-negative oral cavity squamous cell carcinoma was associated with improved mortality. (Source: CancerNetwork)
Source: CancerNetwork - July 21, 2017 Category: Cancer & Oncology Authors: Leah Lawrence Tags: Head & Neck Cancer News Source Type: news

Foundation Medicine to support enrolment for Kura Oncology ’s SCCHN trials
US-based biopharmaceutical firm Kura Oncology has signed a collaboration agreement with Foundation Medicine to support patient enrolment into its clinical programme of tipifarnib to treat relapsed and / or refractory HRAS mutant squamous cell carcino … (Source: Drug Development Technology)
Source: Drug Development Technology - July 16, 2017 Category: Pharmaceuticals Source Type: news

Perineural Invasion Ups Mortality Risk in Squamous Cell Skin CA Perineural Invasion Ups Mortality Risk in Squamous Cell Skin CA
Patients with cutaneous squamous cell carcinoma (CSCC) and perineural invasion (PNI) are at increased risk of death, particularly when PNI is identified clinically or radiologically and not only microscopically, researchers say.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - July 13, 2017 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Three-Weekly Cisplatin Superior to Weekly Dose in Head and Neck Cancer
Three-weekly cisplatin is superior to a weekly dose in preventing locoregional relapse when combined with radiotherapy in head and neck squamous cell carcinoma. (Source: CancerNetwork)
Source: CancerNetwork - July 3, 2017 Category: Cancer & Oncology Authors: Dave Levitan Tags: Head & Neck Cancer News Source Type: news

As One Type of Esophageal Cancer Declines, Another Rises Sharply As One Type of Esophageal Cancer Declines, Another Rises Sharply
Even as the incidence of esophageal squamous cell carcinoma (ESCC) continues to decline in most countries, the incidence of esophageal adenocarcinoma (EAC) is rising to at least a comparable extent, according to a new study of 12 nations.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - June 28, 2017 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news