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Should Some Oropharyngeal Cancer Patients Skip Adjuvant Chemo, Radiation With TORS? Should Some Oropharyngeal Cancer Patients Skip Adjuvant Chemo, Radiation With TORS?
For patients with oropharyngeal squamous cell carcinoma (OPSCC) receiving transoral robotic surgery (TORS), adjuvant radiotherapy or chemoradiotherapy (CRT) should be avoided if possible, according to a long-term functional and quality-of-life (QOL) outcomes study.Reuters Health Information (Source: Medscape Radiology Headlines)
Source: Medscape Radiology Headlines - November 6, 2017 Category: Radiology Tags: Hematology-Oncology News Source Type: news

A squamous cell carcinoma that disproportionately affects men
Factors that drive lip squamous cell carcinomas in men. (Source: Dermatology Times)
Source: Dermatology Times - November 1, 2017 Category: Dermatology Source Type: news

Report: Doctor self-diagnoses cancer while testing Butterfly iQ ultrasound
A vascular surgeon was able to diagnose his own cancer while testing the Butterfly Network’s Butterfly iQ ultrasound-on-a-chip device, according to a report from USA Today. After experiencing some throat discomfort Dr. John Martin self-tested the device, designed to send images to and operate in conjunction with Apple (NSDQ:AAPL) iPhones, and found a mass that he thought looked cancerous, according to the report. The mass turned out to be squamous cell cancer which Martin has since received treatment for, including surgery and radiation therapy. “I felt something funny in my neck, connected the probe to my...
Source: Mass Device - October 30, 2017 Category: Medical Devices Authors: Fink Densford Tags: Imaging Oncology Apple butterflynetwork Source Type: news

Skin Cancer Melanoma Squamous Cell Basal Cell
Skin Cancer (Melanoma, Squamous Cell, Basal Cell Cancer) in Children (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - October 24, 2017 Category: General Medicine Source Type: news

New Guidelines a Boon for Skin Cancer Staging
(MedPage Today) -- AJCC-8 guide expands definition of T3 cutaneous squamous cell carcinoma (Source: MedPage Today Dermatology)
Source: MedPage Today Dermatology - October 15, 2017 Category: Dermatology Source Type: news

Your NEJM Group Today: Squamous Cell Carcinoma of the Mouth / Asthma Treatments Compared / California Family Medicine Opportunity (FREE)
By the Editors Take a look at today's offering from NEJM Group:NEJM Clinical Practice Center: Image in Clinical Medicine: A 54-year-old woman who regularly chewed … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - September 27, 2017 Category: Primary Care Source Type: news

Tailored Treatment for Head-and-Neck Cancer Mystery
Treatment TermsHead and Neck Cancer Overview Rob Vaughn found a lump on his neck that turned out to be cancer that had spread from somewhere else in his body. The trouble was, doctors couldn ’t find the original site of the cancer. That made his treatment decisions difficult -- until two Duke specialists offered him options, including the option for watchful waiting instead of extensive treatment. Hero Image20170914_robvaughn_neckcancer_083_herocrop.jpg Preview Image Content Blocks Header A Search for the Source of Cancer ContentVaughn, a Charlotte, NC, father of two, was 47 and in good health when he felt th...
Source: dukehealth.org: Duke Health News - September 15, 2017 Category: Consumer Health News Authors: mf205 at duke.edu Source Type: news

Regeneron and Sanofi receive FDA ’s breakthrough therapy status for CSCC treatment with cemiplimab
US-based Regeneron Pharmaceuticals and French company Sanofi have received breakthrough therapy designation status for cemiplimab (REGN2810) from the US Food and Drug Administration (FDA) to treat cutaneous squamous cell carcinoma (CSCC). (Source: Pharmaceutical Technology)
Source: Pharmaceutical Technology - September 10, 2017 Category: Pharmaceuticals Source Type: news

Sanofi and Regeneron announce that cemiplimab (REGN2810) has received FDA Breakthrough Therapy designation for advanced cutaneous squamous cell carcinoma
Sanofi and Regeneron Pharmaceuticals, Inc. today announced that the U.S. Food and Drug Administration (FDA) has granted Breakthrough Therapy designation status to cemiplimab (REGN2810) for the treatment of adults with metastatic cutaneous squamous cell carcinoma (CSCC) and adults with locally advanced and unresectable CSCC, the second deadliest skin cancer after melanoma[1], [2]. Cemiplimab is an investigational human, monoclonal antibody targeting PD-1. (Source: World Pharma News)
Source: World Pharma News - September 8, 2017 Category: Pharmaceuticals Tags: Featured Sanofi Business and Industry Source Type: news

Regeneron and Sanofi Announce Cemiplimab (REGN2810) Has Received FDA Breakthrough Therapy Designation for Advanced Cutaneous Squamous Cell Carcinoma
TARRYTOWN, N.Y. and PARIS, Sept. 8, 2017 -- (Healthcare Sales & Marketing Network) -- Regeneron Pharmaceuticals, Inc. (NASDAQ: REGN) and Sanofi today announced that the U.S. Food and Drug Administration (FDA) has granted Breakthrough Therapy designation s... Biopharmaceuticals, Oncology Regeneron Pharmaceuticals, Sanofi, cemiplimab, cutaneous squamous cell carcinoma (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - September 8, 2017 Category: Pharmaceuticals Source Type: news

Gliknik commences dosing in Phase II oral cavity cancer trial
US-based biopharmaceutical firm Gliknik has commenced patient dosing in a Phase II clinical trial of immunomodulatory therapeutic biropepimut-S (GL-0817) to prevent recurrence of oral cavity squamous cell cancer. (Source: Drug Development Technology)
Source: Drug Development Technology - August 29, 2017 Category: Pharmaceuticals Source Type: news

Newly developed nomograms provide accurate predictions for patients with oropharyngeal cancer
(NRG Oncology) NRG Oncology researchers recently developed and validated a nomogram that can predict 2-year and 5-year overall survival (OS) and progression-free survival (PFS) for patients with local-regionally advanced oropharyngeal squamous cell carcinoma (OPSCC) treated primarily with radiation-based therapy. This nomogram was developed with data from clinical trials NRG Oncology/RTOG 0129 and 0522. Results were published online in the Journal of Clinical Oncology on Aug. 4, 2017. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - August 21, 2017 Category: Cancer & Oncology Source Type: news

Nodal Stage Migration in Anal Cancer May Misclassify True Disease Stage
The rate of lymph node positivity in patients with squamous cell carcinoma of the anus may be overestimated, potentially leading to the overtreatment of patients with chemoradiotherapy. (Source: CancerNetwork)
Source: CancerNetwork - August 18, 2017 Category: Cancer & Oncology Authors: Leah Lawrence Tags: Gastrointestinal Cancer News Source Type: news

Anal Cancer More Deadly in Black Men
Significant racial and gender-based disparities exist in outcomes among patients with squamous cell carcinoma of the anus, with black men having the lowest survival rates, according to a new study. (Source: CancerNetwork)
Source: CancerNetwork - August 18, 2017 Category: Cancer & Oncology Authors: Mark L. Fuerst Tags: Gastrointestinal Cancer News Source Type: news

NICE recommends Merck ’s erbitux to treat R/M SCCHN in oral cavity
The UK National Institute for Health and Care Excellence (NICE) has recommended the routine use of Merck ’s erbitux (cetuximab), in combination with platinum-based chemotherapy, to treat recurrent and / or metastatic (R/M) squamous cell carcinoma of t… (Source: Pharmaceutical Technology)
Source: Pharmaceutical Technology - August 9, 2017 Category: Pharmaceuticals Source Type: news

Alcohol linked to an increased risk of skin cancer
Conclusion These findings should be interpreted with care before concluding that an alcoholic drink per day increases your risk of skin cancer. There are several important cautions: These are only observational studies. It wouldn't be possible to randomise people to different alcohol intake and follow them to look at cancer development. And with observational studies, many other health, sociodemographic and lifestyle factors may be influencing the link between alcohol intake and cancer development. The studies differed considerably in terms of the influencing factors they took account of, with some adjusting for various ...
Source: NHS News Feed - August 7, 2017 Category: Consumer Health News Tags: Cancer Source Type: news

Knoxville woman records her fight with deadly skin cancer
Marisha Dotson, 28, from Knoxville in Tennessee, has lost her nose, parts of her jaw and eight teeth during her battle with squamous cell carcinoma. (Source: the Mail online | Health)
Source: the Mail online | Health - August 4, 2017 Category: Consumer Health News Source Type: news

Orphan, 28, documents her battle with deadly skin cancer
Marisha Dotson, 28, from Knoxville in Tennessee, has lost her nose, parts of her jaw and eight teeth during her battle with squamous cell carcinoma. (Source: the Mail online | Health)
Source: the Mail online | Health - August 4, 2017 Category: Consumer Health News Source Type: news

Medical News Today: Every 10 grams of alcohol per day may raise skin cancer risk
The risk of basal and squamous cell carcinomas may increase with every 10 grams of alcohol consumed each day, new research suggests. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - August 2, 2017 Category: Consumer Health News Tags: Alcohol / Addiction / Illegal Drugs Source Type: news

Alcohol increases the risk of skin cancer by up to 11%
Researchers from Brown University found that for every 10 grams of alcohol a day, a person's risk of basal cell carcinoma increases by 7 percent and cutaneous squamous cell carcinoma by 11 percent. (Source: the Mail online | Health)
Source: the Mail online | Health - August 1, 2017 Category: Consumer Health News Source Type: news

Adherence to Quality Metrics Could Improve Head and Neck Cancer Survival
Adherence to each of five quality metrics for head and neck squamous cell carcinoma was associated with a reduced risk for death. (Source: CancerNetwork)
Source: CancerNetwork - July 31, 2017 Category: Cancer & Oncology Authors: Leah Lawrence Tags: Head & Neck Cancer News Source Type: news

Alcohol intake may increase risk of nonmelanoma skin cancers
(Wiley) In a recent analysis of published studies, higher alcohol intake was linked with an increased risk of both basal cell carcinoma and cutaneous squamous cell carcinoma, which are nonmelanoma skin cancers. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - July 31, 2017 Category: International Medicine & Public Health Source Type: news

Melanoma isn't the only serious skin cancer
A type of skin cancer called squamous cell carcinoma (SCC) is increasingly common in the United States. (Source: Health News - UPI.com)
Source: Health News - UPI.com - July 28, 2017 Category: Consumer Health News Source Type: news

Melanoma Isn't the Only Serious Skin Cancer
Squamous cell carcinoma is far more common and also dangerous if untreated, dermatologist says (Source: Cancercompass News: Other Cancer)
Source: Cancercompass News: Other Cancer - July 28, 2017 Category: Cancer & Oncology Source Type: news

Melanoma Isn't the Only Serious Skin Cancer
Squamous cell carcinoma is far more common and also dangerous if untreated, dermatologist says (Source: WebMD Health)
Source: WebMD Health - July 27, 2017 Category: Consumer Health News Source Type: news

Melanoma Isn ’ t the Only Serious Skin Cancer
Squamous cell carcinoma is far more common and also dangerous if untreated, dermatologist says (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - July 27, 2017 Category: Cancer & Oncology Tags: Dermatology, Oncology, News, Source Type: news

Melanoma Isn't the Only Serious Skin Cancer
THURSDAY, July 27, 2017 -- A type of skin cancer called squamous cell carcinoma (SCC) is increasingly common in the United States, so people need to be alert for signs of the disease, an expert says. About 700,000 new cases of this skin cancer are... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - July 27, 2017 Category: General Medicine Source Type: news

Increased Node Dissection Improved Survival in Node-Negative Oral Cavity SCC
Higher nodal yield during definitive surgery for clinically node-negative oral cavity squamous cell carcinoma was associated with improved mortality. (Source: CancerNetwork)
Source: CancerNetwork - July 21, 2017 Category: Cancer & Oncology Authors: Leah Lawrence Tags: Head & Neck Cancer News Source Type: news

Foundation Medicine to support enrolment for Kura Oncology ’s SCCHN trials
US-based biopharmaceutical firm Kura Oncology has signed a collaboration agreement with Foundation Medicine to support patient enrolment into its clinical programme of tipifarnib to treat relapsed and / or refractory HRAS mutant squamous cell carcino … (Source: Drug Development Technology)
Source: Drug Development Technology - July 16, 2017 Category: Pharmaceuticals Source Type: news

Perineural Invasion Ups Mortality Risk in Squamous Cell Skin CA Perineural Invasion Ups Mortality Risk in Squamous Cell Skin CA
Patients with cutaneous squamous cell carcinoma (CSCC) and perineural invasion (PNI) are at increased risk of death, particularly when PNI is identified clinically or radiologically and not only microscopically, researchers say.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - July 13, 2017 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Three-Weekly Cisplatin Superior to Weekly Dose in Head and Neck Cancer
Three-weekly cisplatin is superior to a weekly dose in preventing locoregional relapse when combined with radiotherapy in head and neck squamous cell carcinoma. (Source: CancerNetwork)
Source: CancerNetwork - July 3, 2017 Category: Cancer & Oncology Authors: Dave Levitan Tags: Head & Neck Cancer News Source Type: news

As One Type of Esophageal Cancer Declines, Another Rises Sharply As One Type of Esophageal Cancer Declines, Another Rises Sharply
Even as the incidence of esophageal squamous cell carcinoma (ESCC) continues to decline in most countries, the incidence of esophageal adenocarcinoma (EAC) is rising to at least a comparable extent, according to a new study of 12 nations.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - June 28, 2017 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Nivolumab Maintained QOL in Advanced Squamous Cell Head and Neck Cancer
Patients with recurrent or metastatic squamous cell carcinoma of the head and neck treated with the checkpoint inhibitor nivolumab were able to maintain baseline levels of quality of life. (Source: CancerNetwork)
Source: CancerNetwork - June 28, 2017 Category: Cancer & Oncology Authors: Leah Lawrence Tags: Head & Neck Cancer News Source Type: news

Immunotherapy Safely Treats Advanced Squamous Cell Carcinoma
An anti –PD-1 monoclonal antibody is safe and effective for patients with unresectable, locally advanced, or metastatic cutaneous squamous cell carcinoma. (Source: CancerNetwork)
Source: CancerNetwork - June 23, 2017 Category: Cancer & Oncology Authors: Mark L. Fuerst Tags: News Skin Cancer (Nonmelanoma) Source Type: news

Tumor PD-L2 expression may predict patient response to anti-PD-1 immunotherapy
(American Association for Cancer Research) PD-L2 protein expression in human tumors was associated with clinical response to pembrolizumab (Keytruda), an anti-PD-1 immunotherapy, independent of PD-L1 expression, in patients with head and neck squamous cell carcinoma (HNSCC). (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 15, 2017 Category: International Medicine & Public Health Source Type: news

Hope for better lung cancer treatment on horizon
(Walter and Eliza Hall Institute) The researchers demonstrated a better way to recruit the right participants for promising new anti-cancer drugs called FGFR (fibroblast growth factor receptor) inhibitors, which are being investigated for treating lung squamous cell carcinoma. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 13, 2017 Category: International Medicine & Public Health Source Type: news

Role for Afatinib in p16-Negative Head and Neck Cancer?
This video reviews results of LUX-Head& Neck 2, a randomized phase III trial that studied afatinib as adjuvant therapy in patients with unresected squamous cell head and neck cancer. (Source: CancerNetwork)
Source: CancerNetwork - June 11, 2017 Category: Cancer & Oncology Authors: Barbara Burtness, MD Tags: Conferences/ASCO Street Team Head & Neck Cancer News Source Type: news

Analysis of pathways activation landscape in oral squamous cell carcinoma and pre-neoplastic lesions
(InSilico Medicine, Inc.) Oral dysplastic lesions are considered precursors of OSCC. However only a subset of such lesions progress to invasive cancer. There is an urgent need for biomarkers, which might assign a risk for cancer development in patients with premalignant lesions. Scientists at the Johns Hopkins University alongside collaborators from Insilico Medicine, Inc, have applied iPANDA, a novel approach for analyzing high-throughput transcriptomic datasets, to identify the earliest signaling harbingers of malignant transition. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - June 6, 2017 Category: Biology Source Type: news

7 medtech stories we missed this week: June 2, 2017
[Photo from unsplash.com]From Implandata receiving CE Marking to Inolife eyeing up-listing, here are 7 medtech stories we missed this week but thought were still worth mentioning. 1. Dextera seeks expanded indications for MicroCutter 5/80 stapler Dextera Surgical announced in a June 1 press release that it has filed a 510(k) with the FDA for its MicroCutter 5/80 stapler. The company wants to expand the indications of the MicroCutter 5/80 for use in liver, pancreas, kidney and spleen surgeries. Currently, the staplers are used for transection and resection in multiple open minimally-invasive urologic, thoracic and...
Source: Mass Device - June 2, 2017 Category: Medical Devices Authors: Danielle Kirsh Tags: Business/Financial News Clinical Trials News Well Regulatory/Compliance Research & Development c2 Therapeutics Dextera Surgical DreaMed Diabetes EndoGastric Solutions Inc. Implandata Inolife MicroTransponder Inc. Source Type: news

DNA vaccine with immunotherapy may treat HPV cancers
A new vaccine therapy has the potential to generate immune responses in patients with head and neck squamous cell carcinoma in HPV patients. (Source: Health News - UPI.com)
Source: Health News - UPI.com - May 31, 2017 Category: Consumer Health News Source Type: news

Immunotherapy with DNA vaccine shows promise for HPV-related head and neck cancer
(University of Pennsylvania School of Medicine) A novel vaccine therapy can generate immune responses in patients with head and neck squamous cell carcinoma (HNSCCa), according to researchers at the Abramson Cancer Center of the University of Pennsylvania. The treatment specifically targets human papillomavirus (HPV), which is frequently associated with HNSCCa, to trigger the immune response. Researchers will present the results of their pilot study during the 2017 American Society of Clinical Oncology Annual Meeting in Chicago (Abstract #6073). (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - May 31, 2017 Category: Cancer & Oncology Source Type: news

Penn studies show hope for multiple cancers with pembrolizumab combination therapies
(University of Pennsylvania School of Medicine) The combination of pembrolizumab and the checkpoint inhibitor known as epacadostat is leading to promising responses and is generally well tolerated in patients with triple-negative breast cancer, non-small cell lung cancer, squamous cell cancer of the head and neck, and several other cancers, according to researchers from the Abramson Cancer Center of the University of Pennsylvania. Their findings also showed that adding pembrolizumab to standard therapies for breast cancer improved the number of patients achieving a pathological complete response. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 30, 2017 Category: International Medicine & Public Health Source Type: news

Texas scientists: Sugar fuels various forms of cancer
University of Texas researchers have shown that squamous cell carcinoma, which can be found in the lungs, cervix and oesophagus, thrives off high amounts of glucose. (Source: the Mail online | Health)
Source: the Mail online | Health - May 26, 2017 Category: Consumer Health News Source Type: news

Sugar IS fuelling various forms of cancer
University of Texas researchers have shown that squamous cell carcinoma, which can be found in the lungs, cervix and oesophagus, thrives off high amounts of glucose. (Source: the Mail online | Health)
Source: the Mail online | Health - May 26, 2017 Category: Consumer Health News Source Type: news

Study sweetens connection between cancer and sugar
(University of Texas at Dallas) In a new study, scientists at the University of Texas at Dallas have found that some types of cancers have more of a sweet tooth than others. 'It has been suspected that many cancer cells are heavily dependent on sugar as their energy supply, but it turns out that one specific type -- squamous cell carcinoma -- is remarkably more dependent,' said Dr. Jung-whan 'Jay' Kim, senior author of the study. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - May 26, 2017 Category: Cancer & Oncology Source Type: news

Genetic risk factor for equine eye cancer identified
(University of California - Davis) UC Davis researchers have identified a genetic mutation in horses that should help identify horses that are at risk for squamous cell carcinoma of the eye and enable horse owners to make informed breeding decisions. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - May 24, 2017 Category: Cancer & Oncology Source Type: news

Skin cancer on the rise
New diagnoses for two types of skin cancer increased in recent years, according to a team of researchers. Their paper uses medical records from the Rochester Epidemiology Project to compare diagnoses of basal cell carcinoma and squamous cell carcinoma ? both nonmelanoma skin cancers ? between 2000 and 2010 to diagnoses in prior years. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - May 15, 2017 Category: Science Source Type: news

Head & neck cancer recurrence following radiation associated w high tumor PD-L1 expression
(American Association for Cancer Research) Recurrence of head and neck squamous cell carcinoma (HNSCC) negative for human papillomavirus (HPV) following radiation therapy was associated with high tumor levels of the protein PD-L1. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - May 5, 2017 Category: Cancer & Oncology Source Type: news

Head & neck cancer recurrence following radiation associated with high tumor PD-L1 expression
(American Association for Cancer Research) Recurrence of head and neck squamous cell carcinoma (HNSCC) negative for human papillomavirus (HPV) following radiation therapy was associated with high tumor levels of the protein PD-L1. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - May 5, 2017 Category: Cancer & Oncology Source Type: news

Surgery, Radiation Improve Survival in Some Oral Cancer Patients Surgery, Radiation Improve Survival in Some Oral Cancer Patients
Surgery and radiotherapy may be a better course than organ preservation with concurrent chemoradiotherapy in selected patients with oral cavity squamous cell cancer, according to Illinois-based researchers.Reuters Health Information (Source: Medscape Radiology Headlines)
Source: Medscape Radiology Headlines - April 28, 2017 Category: Radiology Tags: Hematology-Oncology News Source Type: news