Neoadjuvant PD-1 Blockade for Elderly Esophageal Squamous Cell Carcinoma (BLESS)
Conditions: Esophageal Cancer Interventions: Drug: neoadjuvant anti-PD-1; Drug: neoadjuvant anti-PD-1 with LDRT Sponsors: Shanghai Chest Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 26, 2024 Category: Research Source Type: clinical trials

Study of Cemiplimab Alone or in Combination With Fianlimab and/or Other Experimental Agents in Adult Participants With Peri-operative Stage III/IV Cutaneous Squamous Cell Carcinoma (CSCC)
Conditions: Cutaneous Squamous Cell Carcinoma Interventions: Drug: cemiplimab; Drug: fianlimab Sponsors: Regeneron Pharmaceuticals Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 25, 2024 Category: Research Source Type: clinical trials

A Study of Amivantamab Alone or in Addition to Other Treatment Agents in Participants With Recurrent/Metastatic Head and Neck Cancer
Conditions: Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma Interventions: Biological: Amivantamab; Biological: Pembrolizumab; Drug: Paclitaxel Sponsors: Janssen Research& Development, LLC Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 25, 2024 Category: Research Source Type: clinical trials

Skin Cancer and Hyperthermia and Radiotherapy
Conditions: Basal Cell Carcinoma; Squamous Cell Carcinoma Skin; Non-melanoma Skin Cancer Interventions: Combination Product: Water-filtered infrared-A-hyperthermia (wIRA) hyperthermia combined; Radiation: Radiotherapy (RT) Sponsors: Kantonsspital Winterthur KSW; Luzerner Kantonsspital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 25, 2024 Category: Research Source Type: clinical trials

Osimertinib as Neoadjuvant Therapy in Patients With Resectable Stage II-IIIB EGFR-mutated Lung Squamous Cell Carcinoma
Conditions: Lung Cancer; Carcinoma, Squamous Cell Interventions: Drug: Osimertinib Sponsors: The First Affiliated Hospital of Guangzhou Medical University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 25, 2024 Category: Research Source Type: clinical trials

A Clinical Study of Anti-CD70 UCAR-T in Relapsed or Refractory Solid Tumors
Conditions: Metastatic Tumor; Advanced Solid Tumor; Renal Cell Carcinoma; Ovarian Cancer; Cervix Cancer; Head and Neck Squamous Cell Carcinoma; Nasopharyngeal Carcinoma Interventions: Drug: CHT101 Sponsors: Zhejiang University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 25, 2024 Category: Research Source Type: clinical trials

Raman Spectroscopy and Skin Cancer
Conditions: Skin Cancer; Basal Cell Carcinoma; Squamous Cell Carcinoma Interventions: Device: Raman Spectroscopy handheld probe (EmVision, FL, USA); Device: Raman Spectroscopy laser source (Hubner Photonics Inc, CA, USA) Sponsors: Renee Cattell Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 25, 2024 Category: Research Source Type: clinical trials

A Phase I/II Trial of UCB4594 in Participants With Advanced Cancer
Conditions: Advanced Solid Tumours; Squamous Cell Carcinoma of Head and Neck; Carcinoma, Non-Small-Cell Lung; Colorectal Neoplasms; Triple Negative Breast Neoplasms; Carcinoma, Renal Cell (Clear Cell Only); Esophageal Neoplasms; Stomach Neoplasms (Excluding Gastrointestinal Stromal Tumors); Uterine Cervical Neoplasms; Ovarian Neoplasms; Pancreatic Neoplasms Interventions: Drug: UCB4594 Sponsors: Cancer Research UK; UCB Biopharma SRL Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 24, 2024 Category: Research Source Type: clinical trials

Head and Neck Carcinoma Clinical Research Platform for Molecular and Blood-based Biomarkers, Treatment and Outcome
Conditions: Squamous Cell Carcinoma of the Oral Cavity; Squamous Cell Carcinoma of the Oropharynx; Squamous Cell Carcinoma of the Hypopharynx; Squamous Cell Carcinoma of the Larynx Interventions: Other: data collection Sponsors: AIO-Studien-gGmbH; Merck Sharp& Dohme LLC Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 24, 2024 Category: Research Source Type: clinical trials

BAI-BACE for Advanced Lung Squamous Cell Carcinoma
Conditions: Squamous Cell Carcinoma Interventions: Procedure: BAI-BACE Sponsors: Sun Yat-sen University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 22, 2024 Category: Research Source Type: clinical trials

A Study of LVGN6051 Combination Therapy in Patient With Head and Neck Squamous Cell Carcinoma (HNSCC)
Conditions: Head and Neck Squamous Cell Carcinoma Interventions: Combination Product: LVGN6051 Monoclonal Antibody Injection+toripalimab Injection+paclitaxel Injection Sponsors: Lyvgen Biopharma Holdings Limited Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 22, 2024 Category: Research Source Type: clinical trials

A Study of HB-202/HB-201 in People With Human Papilloma Virus 16-Positive Head and Neck Squamous Cell Cancer (HPV 16+ HNSCC)
Conditions: HPV16+ Squamous Cell Carcinoma Interventions: Drug: HB-200; Other: Placebo Sponsors: Memorial Sloan Kettering Cancer Center; Hookipa Biotech GmbH; Naveris Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 18, 2024 Category: Research Source Type: clinical trials

10-year Retrospective Study of Oral and Maxillofacial Squamous Cell Carcinoma
Conditions: HNSCC; AI; Radiomic; MRI Interventions: Diagnostic Test: The Resnet50 deep learning (DL) model Sponsors: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 16, 2024 Category: Research Source Type: clinical trials

App-based Recording and Optimization of the Nutritional Status in Patients With Head and Neck Tumors During and After Radio(Chemo)Therapy
Conditions: Squamous Cell Carcinoma of Head and Neck Interventions: Procedure: App Usage; Other: Standard of Care Sponsors: University of Erlangen-N ürnberg Medical School Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 16, 2024 Category: Research Source Type: clinical trials

Tirelizumab in Combination With Carboplatin and Polymeric Micellar Paclitaxel for Neoadjuvant Therapy in cN+ HNSCC
Conditions: Head and Neck Squamous Cell Carcinoma; Head and Neck Cancer; HNSCC; Head Cancer Neck Interventions: Drug: Carboplatin; Drug: Tislelizumab; Drug: Polymeric Micellar Paclitaxel; Procedure: Surgical Resection of Primary +/- Neck Dissection; Radiation: Post-operative radiation therapy Sponsors: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 16, 2024 Category: Research Source Type: clinical trials