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An Early Phase Study of Abraxane Combined With Phenelzine Sulfate in Patients With Metastatic or Advanced Breast Cancer
Condition:   Metastatic Breast Cancer Interventions:   Drug: Nanoparticle albumin-bound paclitaxel;   Drug: Phenelzine Sulfate Sponsors:   EpiAxis Therapeutics;   The Canberra Hospital;   Southern Medical Day Care Centre Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 23, 2018 Category: Research Source Type: clinical trials

Evaluating the Safety and Immunogenicity of the IHV01 Protein Vaccine Primed and Co-Administered With HIV DNA CON-S Env Vaccine in Healthy, HIV-1-Uninfected Adults
Condition:   HIV Infections Interventions:   Biological: DNA CON-S env;   Biological: IHV01;   Biological: Placebo Sponsor:   National Institute of Allergy and Infectious Diseases (NIAID) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 23, 2018 Category: Research Source Type: clinical trials

Silent Atrial Fibrillation in Patients With Mitral Stenosis and Sinus Rhythm and Its Correlation Left Atrial Thrombus
Conditions:   Atrial Fibrillation;   Left Atrial Thrombosis;   Mitral Valve Stenosis Interventions:   Device: 12 lead electrocardiogram;   Device: Holter Monitor;   Device: Transthoracic echocardiogram;   Device: Transesophageal echocardiogram Sponsor:   Assiut University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 23, 2018 Category: Research Source Type: clinical trials

Bleeding In Thrombocytopenia Explained
Conditions:   Hematologic Neoplasms;   Bleeding;   Hemorrhage;   Platelet Transfusion Interventions:   Diagnostic Test: Blood withdrawal;   Other: Questionnaire for former bleeding events Sponsor:   Sanquin-LUMC J.J van Rood Center for Clinical Transfusion Research Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 23, 2018 Category: Research Source Type: clinical trials

Pre-Symptomatic Study of Intravenous AVXS-101 in Spinal Muscular Atrophy (SMA) for Patients With Multiple Copies of SMN2
Condition:   Spinal Muscular Atrophy Intervention:   Biological: AVXS-101 Sponsor:   AveXis, Inc. Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 23, 2018 Category: Research Source Type: clinical trials

The Effect of Goal-directed Hemodynamic Therapy in Radical Cystectomy
Conditions:   Bladder Cancer;   Radical Cystectomy Intervention:   Other: Goal-directed therapy Sponsor:   Seoul National University Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 23, 2018 Category: Research Source Type: clinical trials

A Non-Interventional Interview Study of Phenylketonuria (PKU) Adults
Condition:   Phenylketonuria (PKU) Intervention:   Sponsor:   BioMarin Pharmaceutical Enrolling by invitation (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 23, 2018 Category: Research Source Type: clinical trials

Impact of Telemedicine in the Rate of Readmission for COPD. Project CRONEX 3.0
Condition:   COPD Interventions:   Device: Group intervention;   Other: health care system Sponsor:   Sociedad Española de Neumología y Cirugía Torácica Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 23, 2018 Category: Research Source Type: clinical trials

This Study in Healthy Men and Women Tests How the Body Takes up BI 409306
Condition:   Healthy Interventions:   Drug: BI 409306 (C-13/N-15);   Drug: BI 409306 Sponsor:   Boehringer Ingelheim Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 23, 2018 Category: Research Source Type: clinical trials

The Role of suPAR Biomarker in Blood Samples of Breast Cancer Patients During and Post Doxorubicin Chemotherapy: Causative vs. Predictor
Conditions:   Doxorubicin Adverse Reaction;   Cardiomyopathies, Secondary;   Breast Cancer Intervention:   Sponsor:   Rush University Medical Center Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 23, 2018 Category: Research Source Type: clinical trials

Characterization of the Gut Microbiota Composition and Activity After Three Weeks of Chitin-glucan Supplementation
Condition:   Healthy Intervention:   Dietary Supplement: Chitin-glucan fiber Sponsor:   Nathalie Delzenne Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 23, 2018 Category: Research Source Type: clinical trials

A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of RO7062931 in Healthy Chinese Volunteers.
Condition:   Healthy Participants Interventions:   Drug: RO7062931;   Drug: Placebo Sponsor:   Hoffmann-La Roche Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 23, 2018 Category: Research Source Type: clinical trials

Sleep-Safe: A Strong African American Families Study
Condition:   Weight Gain Interventions:   Behavioral: Sleep Soothe;   Behavioral: Sleep Safe Sponsors:   University of Georgia;   Augusta University;   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 23, 2018 Category: Research Source Type: clinical trials

Swiss Paediatric Airway Cohort
Conditions:   Asthma;   Wheezing;   Cough;   Exercise Induced Bronchospasm;   Vocal Cord Dysfunction Intervention:   Sponsors:   University of Bern;   University Children's Hospital Zuerich;   Cantonal Hospital, Lucerne;   University Children's Hospital Basel, UKBB;   University Hospital Inselspital, Bern;   Children's Hospital of St. Gallen Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 23, 2018 Category: Research Source Type: clinical trials

Span-C-SBRT for Pancreatic Cancer
Condition:   High Risk Localised Pancreatic Cancer Intervention:   Radiation: Stereotactic Body Radiotherapy (SBRT) Sponsor:   Royal North Shore Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 23, 2018 Category: Research Source Type: clinical trials

Application of Bronchial Blocker in Minimally Invasive Cardiac Surgery
Condition:   Minimally Invasive Cardiac Surgery Interventions:   Device: bronchial blocker for BB group;   Device: double lumen tube for DLT group Sponsor:   Shanghai Zhongshan Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 23, 2018 Category: Research Source Type: clinical trials

Comparison Between Intraperitoneal Versus Intramuscular Neostigmine on Pattern of Postoperative GIT Motility in Patients Undergoing Laparoscopic Cholecystectomy
Condition:   Pattern of GIT Motility Interventions:   Drug: Neostigmine;   Other: Normal saline Sponsor:   Assiut University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 23, 2018 Category: Research Source Type: clinical trials

The Impact of Telehealthcare Intervention on Glycemic Control in Children and Adolescents With Type 1 Diabetes
Condition:   Type 1 Diabetes Mellitus Intervention:   Behavioral: Telemedicine Sponsor:   Assuta Hospital Systems Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 23, 2018 Category: Research Source Type: clinical trials

Evaluation of a Functional Lymphocyte Test (QuantiFERON Monitor ®) as a Prognostic Marker for Acute Community-acquired Pneumonia
Condition:   Pneumonia Intervention:   Biological: Blood samples Sponsor:   Centre Hospitalier Universitaire Dijon Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 23, 2018 Category: Research Source Type: clinical trials

The Effect of Task-Oriented Training in Patients With Multiple Sclerosis
Condition:   Multiple Sclerosis Intervention:   Other: Task-oriented training Sponsor:   Gazi University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 23, 2018 Category: Research Source Type: clinical trials

Lynparza Ovarian Cancer Clinical Experience Investigation (All Case Investigation)
Condition:   Ovarian Cancer Intervention:   Sponsor:   AstraZeneca Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 23, 2018 Category: Research Source Type: clinical trials

A Study to Assess the Antitumor Activity, Safety, Pharmacokinetics and Biomarkers of IMAB362 in Participants With Claudin (CLDN) 18.2 Positive, Metastatic or Advanced Unresectable Gastric and Gastroesophageal Junction (GEJ) Adenocarcinoma
Conditions:   Pharmacokinetics of IMAB362;   Gastric Cancer;   Gastro-esophageal Junction (GEJ) Cancer;   Pharmacokinetics of Oxaliplatin;   Pharmacokinetics of Fluorouracil Bolus (5-FU) Interventions:   Drug: IMAB362;   Drug: oxaliplatin;   Drug: leucovorin;   Drug: fluorouracil Sponsor:   Astellas Pharma Global Development, Inc. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 23, 2018 Category: Research Source Type: clinical trials

Liga Sure Versus Conventional Suture Ligature for Decrease Blood Loss During Abdominal Hysterectomy
Condition:   Decrease Blood Loss During Abdominal Hysterectomy Intervention:   Procedure: conventional suture Sponsor:   Aswan University Hospital Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 23, 2018 Category: Research Source Type: clinical trials

68 Ga-NODAGA-E[c(RGD γK)]2: Positron Emission Tomography Tracer for Imaging of Angiogenesis in Ischemic Heart Disease
Condition:   Chronic Ischemic Heart Disease Intervention:   Drug: 68Ga-NODAGA-E[c(RGDyK)]2 Sponsor:   Rigshospitalet, Denmark Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 23, 2018 Category: Research Source Type: clinical trials

Post-operative Rehabilitation Protocol for Combined Reconstruction of Anterior Cruciate Ligament and Anterolateral Knee Ligament Surgery
Conditions:   Anterior Cruciate Ligament Reconstruction;   Anterolateral Ligament Reconstruction;   Rehabilitation Interventions:   Other: partial knee immobilization protocol;   Other: standard ACL reconstruction rehabilitation protocol Sponsor:   University of Sao Paulo General Hospital Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 23, 2018 Category: Research Source Type: clinical trials

Role of Contrast Enhanced Spectral Mammography to Predict Upgrade Rates of Biopsy Proven Atypical Ductal Hyperplasia
Condition:   Atypical Ductal Hyperplasia Intervention:   Device: Contrast enhanced mammography Sponsors:   Dana-Farber Cancer Institute;   GE Healthcare Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 23, 2018 Category: Research Source Type: clinical trials

Effects of a Unique Co-created Intervention With Care Home Residents and University Students Following a Service-learning Methodology to Reduce Sedentary Behaviour.
Conditions:   Physical Activity;   Sedentary Behaviour;   Care Home Residents Intervention:   Behavioral: Co-created intervention Sponsor:   Glasgow Caledonian University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 23, 2018 Category: Research Source Type: clinical trials

Study of Visual-spatial Attention by Eye Tracking as a Function of Central or Peripheral Visual Impairment
Condition:   Central or Peripheral Visual Impairment Interventions:   Procedure: microperimetry;   Procedure: visual acuity;   Procedure: automated visual field;   Procedure: eye movements recording Sponsor:   Nantes University Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 23, 2018 Category: Research Source Type: clinical trials

The Influence of Melatonin Supplementation in the Group of Persons Performing Competitive Sport.
Conditions:   Antioxidants;   Oxidative Stress;   Inflammation;   Lipid Peroxidation Intervention:   Dietary Supplement: melatonin supplementation Sponsor:   Nicolaus Copernicus University Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 23, 2018 Category: Research Source Type: clinical trials

Supporting All Families of Premature Infants at Prentice Women's Hospital From Admission Through Discharge
Conditions:   Premature Infant;   Premature Birth;   NICU Interventions:   Other: Group 1: Standard of Care;   Other: Group 2: SMART NICU2HOME app Sponsors:   Northwestern University;   Friends of Prentice Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 23, 2018 Category: Research Source Type: clinical trials

Effects of Stress on Exposure Therapy
Condition:   Specific Phobia Interventions:   Other: Cold water condition;   Other: Warm water condition Sponsor:   Ruhr University of Bochum Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 23, 2018 Category: Research Source Type: clinical trials

Effects of Population Compared to Purposive Sampling for Consensus in an Online Delphi Study
Condition:   Behavior, Consumer Interventions:   Other: Population Sample;   Other: Purposive sample Sponsor:   ThinkWell Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 23, 2018 Category: Research Source Type: clinical trials

The Neuroinflammatory Response and Biomarkers in Acute Traumatic Spinal Cord Injury
Condition:   Spinal Cord Injury, Acute Interventions:   Other: Blood samples;   Other: Cerebrospinal fluid sample;   Other: Clinical examination Sponsors:   University of Aarhus;   Aarhus University Hospital;   Spinal Cord Injury Centre of Western Denmark Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 23, 2018 Category: Research Source Type: clinical trials

Optimizing the Previs Device for Prediction of Postoperative Ileus
Condition:   Ileus Interventions:   Device: Entac Medical device application;   Other: Patient Daily Assessment;   Other: Patient Discharge Assessment Sponsor:   Jennifer Hrabe Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 23, 2018 Category: Research Source Type: clinical trials

The Effect of Deep Inhalation on Mannitol Responsiveness
Condition:   Asthma Interventions:   Procedure: Deep inhalation technique;   Procedure: Tidal breathing technique;   Drug: Methacholine;   Drug: Mannitol Sponsor:   University of Saskatchewan Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 23, 2018 Category: Research Source Type: clinical trials

Reducing Blood Loss During Cesarean Myomectomy With Tranexamic Acid
Condition:   Cesarean Section Complications Intervention:   Drug: IV tranexamic acid Sponsor:   Aswan University Hospital Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 23, 2018 Category: Research Source Type: clinical trials

Treatment Patterns, Clinical Outcomes, and Healthcare Resource Utilization Associated With Chinese Patients With Advanced Lung Cancer
Conditions:   Lung Cancer;   Non-small Cell Lung Cancer NSCLC;   Small Cell Lung Cancer SCLC Intervention:   Other: Non-interventional Sponsor:   Bristol-Myers Squibb Active, not recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 23, 2018 Category: Research Source Type: clinical trials

Intrathecal Transplantation of UC-MSC in Patients With Late Stage of Chronic Spinal Cord Injury
Condition:   Spinal Cord Injuries Intervention:   Drug: Umbilical Cord Mesenchymal Stem Cells Sponsors:   Third Affiliated Hospital, Sun Yat-Sen University;   West China Hospital;   Shanghai East Hospital Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 23, 2018 Category: Research Source Type: clinical trials

Adipokines Effect in Myometrial Contractility
Condition:   Myometrium; Contractility Intervention:   Biological: Adiponectin and TNFa Sponsor:   University of Minnesota - Clinical and Translational Science Institute Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 23, 2018 Category: Research Source Type: clinical trials

A Study of Oral Lorlatinib in Patients With Relapsed ALK Positive Lymphoma
Condition:   Anaplastic Large Cell Lymphoma, ALK-Positive Intervention:   Drug: Lorlatinib Sponsors:   University of Milano Bicocca;   Pfizer Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 23, 2018 Category: Research Source Type: clinical trials

Study to Compare Kowa OCT Bi- μ and the Optovue iVue 100
Conditions:   Glaucoma;   Retinal Disease;   Healthy Interventions:   Device: KOWA OCT Bi-µ;   Device: Optovue iVue 100 Sponsor:   Kowa Research Institute, Inc. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 23, 2018 Category: Research Source Type: clinical trials

AMIStem-H Radological Assessment
Condition:   Hip Replacement Arthroplasty Intervention:   Sponsor:   Medacta International SA Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 23, 2018 Category: Research Source Type: clinical trials

[Trial of device that is not approved or cleared by the U.S. FDA]
Condition:   Intervention:   Sponsor:   [Redacted] Withheld (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 23, 2018 Category: Research Source Type: clinical trials

New Visual Acuity and Crowding Tests for Better Detection of Amblyopia
Condition:   Amblyopia Intervention:   Diagnostic Test: Visual acuity tests Sponsor:   Anglia Ruskin University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 23, 2018 Category: Research Source Type: clinical trials

ASSIST 1.0 an Intervention Program Addressing Reablement Services
Conditions:   Older Adults;   Participation Intervention:   Behavioral: ASSIST 1.0 Sponsor:   Karolinska Institutet Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 23, 2018 Category: Research Source Type: clinical trials

High Versus Low Positive End Expiratory Pressure With Alveolar Recruitment Maneuver in Laparoscopic Bariatric Surgeries
Condition:   Anesthesia Interventions:   Device: Recruitment with low PEEP;   Device: High PEEP without RM Sponsor:   Mansoura University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 23, 2018 Category: Research Source Type: clinical trials

Surgical Techniques in Arthroplasty of the Knee (STArK) 1 Trial
Condition:   Pain, Postoperative Interventions:   Procedure: Periarticular infiltration;   Procedure: Intra-articular infiltration Sponsors:   Chloe Scott;   NHS Lothian Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 23, 2018 Category: Research Source Type: clinical trials

Abriendo Caminos 2: Clearing the Path to Hispanic Health
Conditions:   Obesity;   Childhood Obesity;   Nutrient; Excess;   Community Health Education Intervention:   Behavioral: Education and Behavior Sponsors:   University of Illinois at Urbana-Champaign;   California State University, Fresno Foundation;   Iowa State University;   University of Houston;   University of Puerto Rico Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 23, 2018 Category: Research Source Type: clinical trials

Acupuncture in Reducing Chemotherapy-Induced Peripheral Neuropathy in Participants With Stage I-III Breast Cancer
Conditions:   Anatomic Stage I Breast Cancer AJCC v8;   Anatomic Stage IA Breast Cancer AJCC v8;   Anatomic Stage IB Breast Cancer AJCC v8;   Anatomic Stage II Breast Cancer AJCC v8;   Anatomic Stage IIA Breast Cancer AJCC v8;   Anatomic Stage IIB Breast Cancer AJCC v8 ;   Anatomic Stage III Breast Cancer AJCC v8;   Anatomic Stage IIIA Breast Cancer AJC...
Source: ClinicalTrials.gov - April 23, 2018 Category: Research Source Type: clinical trials

Effect of Oral Collagen Tripeptide on Skin Moisture and Wrinkles in Adult Women
Conditions:   Skin Manifestations;   Skin Wrinkling Interventions:   Dietary Supplement: CTP;   Dietary Supplement: placebo (starch) Sponsor:   Pusan National University Yangsan Hospital Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 23, 2018 Category: Research Source Type: clinical trials