A Phase I/II Study of AZD0466 as Monotherapy or in Combination With Anticancer Agents in Advanced Non-Hodgkin Lymphoma
Condition: Non-Hodgkin Lymphoma Intervention: Drug: AZD0466 Sponsor: AstraZeneca Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 25, 2022 Category: Research Source Type: clinical trials
Depth Electrode Detection of Cortical Spreading Depolarization After Traumatic Brain Injury
Condition: TBI (Traumatic Brain Injury) Intervention: Device: depth electrodes Sponsor: University of Minnesota Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 25, 2022 Category: Research Source Type: clinical trials
Gut Microbiota and Metabonomics
Conditions: Stomach Neoplasms; Gut Microbiota; Metabolomics Interventions: Procedure: Healthy control specimen collection; Procedure: Non-Borrmann IV patient specimen collection; Procedure: Borrmann IV patient specimen collection Sponsors: First Hospital of China Medical University; Liaoning Cancer Hospital & Institute; The Second Hospital of Shandong University; The General Hospital of Fushun Mining Bureau; The&nbs...
Source: ClinicalTrials.gov - January 25, 2022 Category: Research Source Type: clinical trials
Immune Therapy in HR-positive/HER2-negative Metastatic Breast Cancer(ENIGMA)
Conditions: Breast Cancer; Metastatic Cancer Interventions: Drug: SHR-1316; Drug: SHR6390; Drug: Nab paclitaxel; Drug: SERD; Drug: AI Sponsor: Fudan University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 25, 2022 Category: Research Source Type: clinical trials
Stepwise for the Treatment of Lateral Incisional Hernias
Conditions: Incisional Hernia; Abdominal Wall Defect; Abdominal Wall Hernia; Hernia Intervention: Other: Surgical Technique (lateral retromuscular preperitoneal) Sponsor: Henares University Hospital Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 25, 2022 Category: Research Source Type: clinical trials
Local Radiotherapy for Residual Tumor Lesions During the First-line Treatment
Condition: Non Small Cell Lung Cancer Intervention: Sponsor: Hunan Province Tumor Hospital Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 25, 2022 Category: Research Source Type: clinical trials
Small Bowel Motility in Patients With Systemic Sclerosis
Condition: System Sclerosis Intervention: Diagnostic Test: Endoluminal image analysis by capsule endoscopy Sponsor: Hospital Universitari Vall d'Hebron Research Institute Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 25, 2022 Category: Research Source Type: clinical trials
Multi Cohort Study of Tazemetostat in Combination With Various Treatments For R/R Hematologic Malignancies
Condition: Relapsed/Refractory Interventions: Drug: Tafasitamab; Drug: Lenalidomide; Drug: Tazemetostat; Drug: Acalabrutinib; Drug: Daratumumab; Drug: Hyaluronidase-Fihj; Drug: Pomalidomide 4 MG; Drug: Dexamethasone 20mg; Drug: Dexamethasone 40mg Sponsor: Epizyme, Inc. Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 25, 2022 Category: Research Source Type: clinical trials
Rivet PVS Therapy in Group 2 PH-HFpEF
Conditions: Heart Failure; Pulmonary Hypertension Intervention: Device: Rivet Shunt Sponsor: NXT Biomedical Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 25, 2022 Category: Research Source Type: clinical trials
Effect of Progressive Isolated Core Stability Training
Conditions: CORE STABILITY; Upper Extremity; Physical Performance Intervention: Other: exercise training Sponsor: Ankara Yildirim Beyazıt University Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 25, 2022 Category: Research Source Type: clinical trials
Molecular Imaging of Inflammation in Parkinson's Disease Using LPS and TSPO-PET/MR
Conditions: Neurodegenerative Diseases; Parkinson Disease Interventions: Drug: Lipopolysaccharide; Radiation: PET/MR with [11C]PBR28 Sponsor: University of Exeter Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 25, 2022 Category: Research Source Type: clinical trials
The Role of Transdermal CO2 in MDA Level in Patient Underwent Abdominal Aortic Temporary Cross Clamp
Condition: Placenta Accreta Intervention: Drug: D'Oxyva Sponsor: Universitas Airlangga Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 25, 2022 Category: Research Source Type: clinical trials
Comparison of the Therapeutic Effects of VR and VR + Metformin in the Treatment of Cesarean Section Scar Defect
Condition: Defect Interventions: Drug: Metformin Hydrochloride Sustained-release Tablets; Procedure: Vaginal repair Sponsor: Xinhua Hospital, Shanghai Jiao Tong University School of Medicine Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 25, 2022 Category: Research Source Type: clinical trials
A Phase Ib/IIa Study of CR6086 in Combination With Balstilimab in pMMR-MSS Metastatic Colorectal Cancer Patients
Conditions: Refractory Metastatic Colorectal Cancer; Solid Tumor; Metastatic Microsatellite-stable Colorectal Cancer; Mismatch Repair Protein Proficient Interventions: Drug: CR6086; Biological: AGEN2034 Sponsors: Rottapharm Biotech; Agenus Inc. Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 25, 2022 Category: Research Source Type: clinical trials
Trans-Pacific Multicenter Collaborative Study of Minimally Invasive Proximal Versus Total Gastrectomy for Proximal Gastric and Gastroesophageal Junction Cancers
Conditions: Gastrostomy; Gastric; GastroEsophageal Cancer Interventions: Other: Standard of Care; Other: Control Group Sponsor: M.D. Anderson Cancer Center Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 25, 2022 Category: Research Source Type: clinical trials
VIGOR: Virtual Genome Center for Infant Health
Conditions: Genetics Disease; Genetics/Birth Defects; Genetic Predisposition to Disease Intervention: Sponsors: Boston Children's Hospital; Boston Medical Center; Baystate Medical Center; UMASS Memorial Medical Center; The Cooper Health System; National Human Genome Research Institute (NHGRI) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 25, 2022 Category: Research Source Type: clinical trials
Effects of Yi Jin Bang Exercise and Usual Exercise Therapy in Adults With Subacromial Pain Syndrome
Condition: Subacromial Pain Syndrome Interventions: Behavioral: 10-week home-based Yi Jin Bang exercise program; Behavioral: 10-week home-based usual exercise therapy program Sponsor: Chinese University of Hong Kong Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 25, 2022 Category: Research Source Type: clinical trials
Assessing the Effect of Nicotine Reduction on ENDS User's Addiction and Exposures
Condition: Electronic Cigarette Use Interventions: Behavioral: 5% nicotine; Behavioral: 3% nicotine; Behavioral: 0% nicotine Sponsor: Florida International University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 25, 2022 Category: Research Source Type: clinical trials
Relationship Between Q-tip Test and Urethral Hypermobility
Condition: Urodynamic Stress Incontinence Intervention: Diagnostic Test: Transperineal ultrasound Sponsor: Kaohsiung Medical University Chung-Ho Memorial Hospital Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 25, 2022 Category: Research Source Type: clinical trials
A Study of Intratumoral Administration of Oncolytic Virus Injection (RT-01) in Patients With Advanced Solid Tumors
Condition: Advanced Solid Tumor Intervention: Biological: Oncolytic Virus Injection(RT-01) Sponsor: First Affiliated Hospital Bengbu Medical College Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 25, 2022 Category: Research Source Type: clinical trials
A Study of Oncolytic Virus Injection (RT-01) in Patients With Advanced Solid Tumors
Condition: Advanced Solid Tumor Intervention: Biological: Oncolytic Virus Injection(RT-01) Sponsor: First Affiliated Hospital Bengbu Medical College Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 25, 2022 Category: Research Source Type: clinical trials
Efficacy of Synchronous and Asynchronous Telerehabilitation in COVID-19 Discharges
Conditions: COVID-19; Telerehabilitation Interventions: Other: Synchronous telerehabilitation programme; Other: Asynchronous telerehabilitation programme Sponsors: Bitlis Eren University; Marmara University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 25, 2022 Category: Research Source Type: clinical trials
Study of the Effects of Itraconazole and Carbamazepine on LY3410738 in Healthy Participants
Condition: Healthy Interventions: Drug: LY3410738; Drug: Itraconazole; Drug: Carbamazepine Sponsors: Eli Lilly and Company; Loxo Oncology, Inc. Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 25, 2022 Category: Research Source Type: clinical trials
Telehealth Exercise Training in Post-COVID Patients
Condition: COVID-19 Interventions: Device: Home-based telehealth exercise training program; Behavioral: Education and self-exercise Sponsor: Tri-Service General Hospital Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 25, 2022 Category: Research Source Type: clinical trials
Sciatic Nerve Blockade by Subgluteal Access 12.5 ml of 1% Lidocaine: US Guidance Versus US Guidance With Electrical Stimulation of Peripheral Nerves (Influence of the Sciatic Nerve Blockade on the Effectiveness of Small Doses of Local Anesthetic.).
Conditions: Nerve Block; Efficiency; Sciatic Nerve; Ultrasonography; Minimum Effective Dose Interventions: Procedure: Sciatic nerve block under ultrasound control with a electrostimulator peripheral nerves 12.5 ml 1% lidocaine; Procedure: sciatic nerve blockade under ultrasound control without a peripheral nerve stimulator 12.5 ml 1% lidocaine Sponsor: Mogilev Regional Clinical Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 25, 2022 Category: Research Source Type: clinical trials
Pharmacokinetics and Safety of Cefazolin 3gm DUPLEX in Adults
Condition: Infections Intervention: Drug: Cefazolin 3gm for Injection USP and Dextrose Injection USP Sponsor: B. Braun Medical Inc. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 25, 2022 Category: Research Source Type: clinical trials
A Clinical Trial to Evaluate the Safety and Efficacy of IBS in Patients With Coronary Artery Disease
Condition: Coronary Artery Disease Intervention: Device: Sirolimus-Eluting Iron Bioresorbable Coronary Scaffold System Sponsor: Biotyx Medical (Shenzhen) Co., Ltd. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 25, 2022 Category: Research Source Type: clinical trials
Telehealth Exercise Intervention to Improve Cardiovascular Health in Lymphoma Survivors, TECHS Trial
Conditions: Hodgkin Lymphoma; Non-Hodgkin Lymphoma Interventions: Other: Exercise Intervention; Other: Questionnaire Administration; Other: Telemedicine Sponsors: City of Hope Medical Center; National Cancer Institute (NCI) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 25, 2022 Category: Research Source Type: clinical trials
Delayed Antibiotic Therapy in Non-severe Ventilator Acquired Pneumonia (VAP)
Conditions: Ventilator Associated Pneumonia; Critical Care; Antibiotic Therapy Interventions: Other: Restrictive antibiotic strategy; Other: Aggressive antibiotic strategy Sponsor: Nantes University Hospital Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 25, 2022 Category: Research Source Type: clinical trials
Does Biological Sex Influence the Cardiac Output Response to Sprint Interval Exercise Training in Humans?
Condition: Exercise Intervention: Other: Sprint interval exercise training Sponsor: McMaster University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 25, 2022 Category: Research Source Type: clinical trials
Prospera Test Evaluation in Cardiac Transplant (ProTECT)
Condition: Heart Transplant Rejection Intervention: Sponsor: Natera, Inc. Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 25, 2022 Category: Research Source Type: clinical trials
Stress and Coping, Resilience, and Compassion Fatigue of Front-line Nurses During COVID-19 Pandemic
Conditions: COVID-19 Pandemic; Stressor, Psychological; Mental Health Issue Intervention: Other: This is a cross-sectional research design. Sponsors: National Taiwan University; National Taiwan University Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 25, 2022 Category: Research Source Type: clinical trials
Trial of Auricular Vagus Nerve Stimulation in Painful Covid Long
Condition: COVID-19 Intervention: Device: Tens Eco Plus Sponsors: Assistance Publique - Hôpitaux de Paris; Schwa medico (device lending) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 25, 2022 Category: Research Source Type: clinical trials
COVID-19 Pandemic and Migraine Disorder, Tension Headache and Epilepsy
Condition: COVID-19 Intervention: Other: Non Sponsor: Aswan University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 25, 2022 Category: Research Source Type: clinical trials
Efficacy of Mesalazine Combined With Biologics in the Treatment of Moderate to Severe Ulcerative Colitis
Conditions: Ulcerative Colitis; Efficacy, Self; Biologics; Mesalazine Interventions: Drug: Infliximab; Drug: Vedolizumab; Drug: Mesalazine Sponsor: Sixth Affiliated Hospital, Sun Yat-sen University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 25, 2022 Category: Research Source Type: clinical trials
In-person Randomized Control Trial of the Incidence of Postoperative Hypoesthesia Among Bilateral Sagittal Split Osteotomy Patients Treated With Ultrasonic vs. Reciprocating Saw Instrumentation
Condition: Postoperative Hypoesthesia Among Bilateral Sagittal Split Osteotomy Patients Interventions: Device: Sonopet ultrasonic saw; Device: Reciprocating saw Sponsor: University of California, San Francisco Enrolling by invitation (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 25, 2022 Category: Research Source Type: clinical trials
A Real-world Study of Donafenib Combined With TACE-based Treatment in Patients With Unresectable HCC
Conditions: Hepatocellular Carcinoma; Donafenib Intervention: Drug: Donafenib combined with TACE Sponsor: Shanghai Zhongshan Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 25, 2022 Category: Research Source Type: clinical trials
Exercise Fatigue Parameters and Endothelial Function in Pediatric Patients With a History of COVID-19 Infection or MIS-C
Conditions: COVID-19; MIS-C Associated With COVID-19 Interventions: Device: Cardiopulmonary exercise test (CPET); Device: Peripheral Arterial Tonography (PAT) using the EndoPAT™ device; Diagnostic Test: Endothelin Sponsors: Rambam Health Care Campus; The Baruch Padeh Medical Center, Poriya Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 25, 2022 Category: Research Source Type: clinical trials
Detection Dogs as a Help in the Detection of COVID-19
Condition: Olfaction Intervention: Behavioral: collection of odour samples Sponsor: Hôpital Universitaire Sahloul Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 25, 2022 Category: Research Source Type: clinical trials
Study of F-652 in Subjects With Corona Virus Disease 2019 (COVID-19) Pneumonia
Condition: COVID-19 Pneumonia Interventions: Biological: F-652; Biological: Placebo Sponsor: EVIVE Biotechnology Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 25, 2022 Category: Research Source Type: clinical trials
The Role of Imaging in the Diagnosis of Acute Appendicitis During the COVID-19 Pandemic
Condition: Appendicitis Intervention: Diagnostic Test: Pre-operative imaging Sponsor: University College London Hospitals Active, not recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 25, 2022 Category: Research Source Type: clinical trials
Oral Health in Covid-19 Survivors
Conditions: COVID-19; Periodontitis Intervention: Sponsor: University of Belgrade Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 25, 2022 Category: Research Source Type: clinical trials
Association of Circulating ACE2 Levels With COVID-19
Condition: Level of ACE2 in COVID 19 Patients Intervention: Diagnostic Test: ACE serum levels Sponsor: Jordan University Hospital Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 25, 2022 Category: Research Source Type: clinical trials
Application of Celiac Plexus Block in Postoperative Analgesia of Upper Abdominal Surgery
Conditions: Pain, Postoperative; Nerve Block Interventions: Procedure: Celiac plexus block; Drug: Ropivacaine Sponsors: Second Affiliated Hospital, School of Medicine, Zhejiang University; Health Commission of Zhejiang Province, China Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 25, 2022 Category: Research Source Type: clinical trials
Expanding Fertility Care to Poor and Low Resourced Settings Study
Conditions: Healthy; Male Infertility; Infertility, Male; Fertility Disorders Intervention: Diagnostic Test: Mail-in semen analysis kit Sponsor: University of California, San Francisco Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 25, 2022 Category: Research Source Type: clinical trials
Phase II Immunogenicity Study of AVX/COVID-12 (Patria) Vaccine in Subjects With Prior SARS-CoV-2 Immunity Evidence
Condition: SARS CoV 2 Infection Interventions: Biological: Recombinant NDV Vectored Vaccine for SARS-CoV-2; Biological: Placebo Sponsors: Laboratorio Avi-Mex, S.A. de C.V.; National Council of Science and Technology, Mexico; Instituto Nacional de Enfermedades Respiratorias Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 25, 2022 Category: Research Source Type: clinical trials
Non-inferiority Trial on Monoclonal Antibodies in COVID-19
Condition: COVID-19 Interventions: Drug: Bamlanivimab Etesevimab; Drug: Sotrovimab; Drug: Casirivimab-Imdevimab Sponsors: Azienda Ospedaliera Universitaria Integrata Verona; Agenzia Italiana del Farmaco; Azienda Sanitaria-Universitaria Integrata di Udine Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 25, 2022 Category: Research Source Type: clinical trials
Investigating Central Neurophysiologic Correlates of Non-Motor Symptoms of Parkinson's Disease
Conditions: Parkinson Disease; Autonomic Dysfunction; Depression Intervention: Device: transcranial magnetic stimulation Sponsor: University of North Carolina, Chapel Hill Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 25, 2022 Category: Research Source Type: clinical trials
Human Milk Oligosaccharides (HMOs) for Irritable Bowel Syndrome (IBS)
Conditions: Irritable Bowel Syndrome; IBS - Irritable Bowel Syndrome Interventions: Dietary Supplement: Human Milk Oligosaccharide Mix; Other: Placebo Sponsor: DSM Nutritional Products, Inc. Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 25, 2022 Category: Research Source Type: clinical trials
The Effect of Plate Size on Food Consumption and Satiety
Conditions: Satiety; Food Consumption Interventions: Behavioral: Food consumption using plates with a diameter of 23 cm.; Behavioral: Washout period; Behavioral: Food consumption using plates with a diameter of 31 cm. Sponsor: Eastern Mediterranean University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 25, 2022 Category: Research Source Type: clinical trials
