Osimertinib as Neoadjuvant Therapy in Patients With Resectable Stage II-IIIB EGFR-mutated Lung Squamous Cell Carcinoma
Conditions: Lung Cancer; Carcinoma, Squamous Cell Interventions: Drug: Osimertinib Sponsors: The First Affiliated Hospital of Guangzhou Medical University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 25, 2024 Category: Research Source Type: clinical trials

A Clinical Study of Anti-CD70 UCAR-T in Relapsed or Refractory Solid Tumors
Conditions: Metastatic Tumor; Advanced Solid Tumor; Renal Cell Carcinoma; Ovarian Cancer; Cervix Cancer; Head and Neck Squamous Cell Carcinoma; Nasopharyngeal Carcinoma Interventions: Drug: CHT101 Sponsors: Zhejiang University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 25, 2024 Category: Research Source Type: clinical trials

Raman Spectroscopy and Skin Cancer
Conditions: Skin Cancer; Basal Cell Carcinoma; Squamous Cell Carcinoma Interventions: Device: Raman Spectroscopy handheld probe (EmVision, FL, USA); Device: Raman Spectroscopy laser source (Hubner Photonics Inc, CA, USA) Sponsors: Renee Cattell Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 25, 2024 Category: Research Source Type: clinical trials

A Phase I/II Trial of UCB4594 in Participants With Advanced Cancer
Conditions: Advanced Solid Tumours; Squamous Cell Carcinoma of Head and Neck; Carcinoma, Non-Small-Cell Lung; Colorectal Neoplasms; Triple Negative Breast Neoplasms; Carcinoma, Renal Cell (Clear Cell Only); Esophageal Neoplasms; Stomach Neoplasms (Excluding Gastrointestinal Stromal Tumors); Uterine Cervical Neoplasms; Ovarian Neoplasms; Pancreatic Neoplasms Interventions: Drug: UCB4594 Sponsors: Cancer Research UK; UCB Biopharma SRL Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 24, 2024 Category: Research Source Type: clinical trials

Head and Neck Carcinoma Clinical Research Platform for Molecular and Blood-based Biomarkers, Treatment and Outcome
Conditions: Squamous Cell Carcinoma of the Oral Cavity; Squamous Cell Carcinoma of the Oropharynx; Squamous Cell Carcinoma of the Hypopharynx; Squamous Cell Carcinoma of the Larynx Interventions: Other: data collection Sponsors: AIO-Studien-gGmbH; Merck Sharp& Dohme LLC Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 24, 2024 Category: Research Source Type: clinical trials

BAI-BACE for Advanced Lung Squamous Cell Carcinoma
Conditions: Squamous Cell Carcinoma Interventions: Procedure: BAI-BACE Sponsors: Sun Yat-sen University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 22, 2024 Category: Research Source Type: clinical trials

A Study of LVGN6051 Combination Therapy in Patient With Head and Neck Squamous Cell Carcinoma (HNSCC)
Conditions: Head and Neck Squamous Cell Carcinoma Interventions: Combination Product: LVGN6051 Monoclonal Antibody Injection+toripalimab Injection+paclitaxel Injection Sponsors: Lyvgen Biopharma Holdings Limited Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 22, 2024 Category: Research Source Type: clinical trials

A Study of HB-202/HB-201 in People With Human Papilloma Virus 16-Positive Head and Neck Squamous Cell Cancer (HPV 16+ HNSCC)
Conditions: HPV16+ Squamous Cell Carcinoma Interventions: Drug: HB-200; Other: Placebo Sponsors: Memorial Sloan Kettering Cancer Center; Hookipa Biotech GmbH; Naveris Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 18, 2024 Category: Research Source Type: clinical trials

10-year Retrospective Study of Oral and Maxillofacial Squamous Cell Carcinoma
Conditions: HNSCC; AI; Radiomic; MRI Interventions: Diagnostic Test: The Resnet50 deep learning (DL) model Sponsors: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 16, 2024 Category: Research Source Type: clinical trials

App-based Recording and Optimization of the Nutritional Status in Patients With Head and Neck Tumors During and After Radio(Chemo)Therapy
Conditions: Squamous Cell Carcinoma of Head and Neck Interventions: Procedure: App Usage; Other: Standard of Care Sponsors: University of Erlangen-N ürnberg Medical School Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 16, 2024 Category: Research Source Type: clinical trials

Tirelizumab in Combination With Carboplatin and Polymeric Micellar Paclitaxel for Neoadjuvant Therapy in cN+ HNSCC
Conditions: Head and Neck Squamous Cell Carcinoma; Head and Neck Cancer; HNSCC; Head Cancer Neck Interventions: Drug: Carboplatin; Drug: Tislelizumab; Drug: Polymeric Micellar Paclitaxel; Procedure: Surgical Resection of Primary +/- Neck Dissection; Radiation: Post-operative radiation therapy Sponsors: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 16, 2024 Category: Research Source Type: clinical trials

PBI-MST-01 (NCT04541108) Substudy AZN-05: Intratumoral Microdosing of Rilvegostomig, Volrustomig, and Sabestomig in HNSCC
Conditions: Head and Neck Squamous Cell Carcinoma Interventions: Biological: Rilvegostomig; Biological: Volrustomig; Biological: Sabestomig; Biological: Pembrolizumab Sponsors: Presage Biosciences; AstraZeneca Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 16, 2024 Category: Research Source Type: clinical trials

Exploring the Optimal Timing of Minimally Invasive Surgery for Esophageal Squamous Cell Carcinoma
Conditions: Time Interventions: Radiation: Neoadjuvant chemradiotherapy; Procedure: Minimally invasive esophagectomy Sponsors: Shanghai Zhongshan Hospital Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 15, 2024 Category: Research Source Type: clinical trials

Radical Synchronous Chemoradiotherapy With DDP/5-FU and PD-1 for Non-metastatic Rectal Squamous Cell Carcinoma
Conditions: Rectal Squamous Cell Carcinoma Interventions: Combination Product: PD-1 and CRT Sponsors: Sixth Affiliated Hospital, Sun Yat-sen University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 15, 2024 Category: Research Source Type: clinical trials

Saliva Testing for High-Risk Human Papillomavirus Infection Oral Cavity and Pharynx Cancer
Conditions: Oropharyngeal Squamous Cell Carcinoma; Human Papillomavirus Infection Interventions: Genetic: Pre-Radiation Dental Evaluation/Sample Collection; Other: Pre-Study Visit; Genetic: Oral Medicine Consultation Visit/Sample Collection Sponsors: Wake Forest University Health Sciences; InnoTech Precision Medicine Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 12, 2024 Category: Research Source Type: clinical trials