Osteoporosis and Sarcopenia Increase Frailty Syndrome in the Elderly

Conclusions World population is aging and the increase in life expectancy is often unhealthy. In particular, musculoskeletal aging, which leads to sarcopenia and osteoporosis, has several causes such as changes in body composition, inflammation, and hormonal imbalance. Sarcopenia, osteoporosis, and more frequently, sarcopenic obesity are commonly associated with aging and frequently closely linked each other, often leading to the development of a frailty syndrome. Frailty syndrome favors an increased risk of loss function in daily activities, for cardiovascular diseases, cancers, falls, and mortality. As the number of elderly people continues to increase, it is important to identify people at risk of frailty early and to treat and/or prevent its damages, developing interventions that can promote a “successful aging.” The complexity and heterogeneity of frailty syndrome requires a multidimensional clinical approach based on healthy nutrition, psychosocial well-being, regular physical exercise, and pharmacological measures, which seem to prevent and control chronic diseases affecting both life expectancy and quality of life, thereby reducing mortality. Of course, new basic and clinical studies are necessary to better understand the complex pathophysiological mechanisms leading to frailty and to carry out effective measures of interventions to prevent its development and treat its damages. Author Contributions EAG, PP, and SM equally contributed to the preparation...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research

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CONCLUSION: Although temporal arteritis is suggestive of GCA, other causes of temporal arteritis can be identified with temporal artery biopsy. PMID: 31201015 [PubMed - as supplied by publisher]
Source: Revue de Medecine Interne - Category: Internal Medicine Tags: Rev Med Interne Source Type: research
Using 3D-printed models based on chest CT scans allows clinicians to personalize...Read more on AuntMinnie.comRelated Reading: AR, 3D printing enhance planning for complex heart surgery Radiologists rally in support of medical 3D printing AR, 3D printing aid presurgical planning for kidney cancer 3D printing reduces liver transplant costs, surgery time 3D printing boosts efficiency of rib fracture repair
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
ConclusionPhenobarbital and sodium valproate were proven to be efficacious in treating convulsive epilepsy in rural northeast China. The patients’ compliance still needs to be improved.
Source: Seizure - Category: Neurology Source Type: research
Really need some help with decision to apply this cycle due to financial constraints. Application is processed by AMCAS but waiting on MCAT to determine which schools to add. Don’t want to add 15-20 more schools if it looks impossible. UofAz Physiology Major / Sports Nutrition Minor Az Resident White Male- From rural and medically underserved community, financially underprivileged. Mother is nurse father was paramedic. MCAT- Waiting for score (taken 5/24/19) Based on practice exams I... Continue Application This Cycle?
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: What Are My Chances? WAMC Medical Source Type: forums
An NHS trust in Doncaster has become to latest to launch an innovative ”passport” scheme to help make care and treatment easier for people with a learning disability.
Source: Nursing Times - Category: Nursing Source Type: news
Publication date: Available online 15 June 2019Source: Trends in Endocrinology &MetabolismAuthor(s): Francisco Westermeier, Todd Holyoak, Joel L. Asenjo, Rodrigo Gatica, Francisco Nualart, Ian Burbulis, Romina BertinatPancreatic β-cells express the gluconeogenic enzymes glucose 6-phosphatase (G6Pase), fructose 1,6-bisphosphatase (FBP), and phosphoenolpyruvate (PEP) carboxykinase (PCK), which modulate glucose-stimulated insulin secretion (GSIS) through their ability to reverse otherwise irreversible glycolytic steps. Here, we review current knowledge about the expression and regulation of these enzymes in the conte...
Source: Trends in Endocrinology and Metabolism - Category: Endocrinology Source Type: research
Publication date: Available online 15 June 2019Source: Journal of Prosthodontic ResearchAuthor(s): Ricardo Schestatsky, Camila Pauleski Zucuni, Kiara Serafini Dapieve, Thiago Augusto Lima Burgo, Aloísio Oro Spazzin, Ataís Bacchi, Luiz Felipe Valandro, Gabriel Kalil Rocha PereiraAbstractPurposeTo characterize the effect of two processing techniques (pressing and CAD/CAM — Computer Aided Design/Computer Aided Machining) of lithium-disilicate (LD) based crowns on the microstructure, topography, roughness, fractal dimension, internal and marginal adaptation.MethodsOne-hundred identical preparations for mono...
Source: Journal of Prosthodontic Research - Category: Dentistry Source Type: research
This study examined postgraduates' personal digital archiving (PDA) practices in China. Based on a case study of the PDA practices of postgraduates in Wuhan University, many problems in PDA were found; postgraduates have a higher awareness of PDA, but the differences between different grades level and disciplines are obvious. Many postgraduates are technological optimists. Those who realize the importance of PDA lack real action and can only use a single strategy. The protection of personal privacy and information security is still challenging. To solve these problems, efforts from individuals and institutions are proposed...
Source: The Journal of Academic Librarianship - Category: Databases & Libraries Source Type: research
Publication date: September 2019Source: The Journal of Academic Librarianship, Volume 45, Issue 5Author(s): Eftichia Vraimaki, Maria Koloniari, Konstantinos Kyprianos, Alexandros KoulourisAbstractWorkplace incivility and its consequences have been studied by many scholars; however, little attention has been given to the phenomenon in the library environment. More specifically, empirical research in the Library and Information Science (LIS) literature has focused on deviant behaviors, such as bullying, mobbing, and aggression, mainly from colleagues and supervisors rather than from users. However, incivility in the workplac...
Source: The Journal of Academic Librarianship - Category: Databases & Libraries Source Type: research
The objective of this study was the evaluation of Hawthorn and Rosemary methanol extracts as preventive treatment in alcoholic liver disease (ALD). ALD rat model was used to measure serum hepatic enzyme levels (AST, ALT, γ-GT and ACP), total bilirubin, liver glycogen, lipid peroxidation, total antioxidant capacity (TAC) and serum lipid profile (total cholesterol, triglycerides, LDL and HDL) as well as histopathological analysis in hepatic tissues was recorder. Phytotreatments showed preventive effect, decreasing AST, γ-GT, lipid peroxidation and bilirubin indictors while TAC and liver glycogen stores increase. ...
Source: Alternative Therapies in Health and Medicine - Category: Complementary Medicine Authors: Tags: Altern Ther Health Med Source Type: research
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