Outbreak Breakthrough: Using Whole-Genome Sequencing to Control Hospital Infection
Carrie Arnold is a freelance science writer living in Virginia. Her work has appeared in Scientific American, Discover, New Scientist, Smithsonian, and more. Background image: Reprinted by permission from Macmillan Publishers Ltd: doi:10.5923/s.microbiology.201401.02 About This Article open Citation: Arnold C. 2015. Outbreak breakthrough: using whole-genome sequencing to control hospital infection. Environ Health Perspect 123:A281–A286; http://dx.doi.org/10.1289/ehp.123-A281 Published: 1 November 2015 PDF Version (2.7 MB) The level of detail provided by whole-genome sequencing could give hospitals the tools they need to stop outbreaks before they start. Background: © hxdbzxy/Shutterstock; E. coli O157:H7 genome map reprinted by permission from Macmillan Publishers Ltd: doi:10.5923/s.microbiology.201401.02 The British soldier on the trauma and burns ward at Queen Elizabeth Hospital Birmingham brought home more than his injuries when he was evacuated from Afghanistan in July 2011. Like many wounded veterans,1 he also carried an opportunistic pathogen called Acinetobacter baumannii that was resistant to numerous classes of antimicrobials. If this specific strain of bacteria spread to others in the hospital, the doctors there would have few, if any, options for treating their patients. Keeping the bacterium contained through vigorous infection control procedures seemed the only hope. After a week, another patient developed symptoms of infection w...
Researchers have developed a self-cleaning plastic wrap that repels bacteria -- and could be used to prevent the transfer of antibiotic resistant superbugs, and other forms of dangerous bacteria.
Just days after health officials urged Americans to throw out their salad kits over E. coli concerns, the Food and Drug Administration announced it's investigating three separate E. coli outbreaks linked to salad products.
Publication date: 14–20 December 2019Source: The Lancet, Volume 394, Issue 10215Author(s): Thais Helena dos Santos, Jose L San Martin, Luis G Castellanos, Marcos A Espinal
Publication date: Available online 12 December 2019Source: Microbial PathogenesisAuthor(s): Peisheng Wang, Huan Zhang, Yutao Liu, Runxia Lv, Xiaoqian Liu, Xiaorui Song, Jingting Wang, Lingyan JiangAbstractSalmonella enterica serovar Typhimurium (S. Typhimurium) is an important intracellular pathogen, causing gastroenteritis or severe systemic infection in a variety of hosts. During infection, S. Typhimurium must survive and replicate in host macrophages, which produce abundant oxidative compounds. SoxRS regulon is a well-known regulator that is activated in response to oxidative stress and promotes bacterial tolerance to o...
ConclusionThe present study reports a variant subgroup GII-a PEDV HM2017 strain in China and characterize its pathogenicity. PEDV strain HM2017 of subgroup GII-a presents a promising vaccine candidate for the control of PED outbreaks in China.
ConclusionThis study shows that NHs within our region are an important reservoir of ESBLE, whereas no residents were CPE carrier. ESBLE control in NHs should focus on antibiotic stewardship and excreta management policies.
ConclusionThis study highlights the presence of colistin-resistant Gram-negative bacteria in a Lebanese hospital, which is worrisome. An urgent strategy needs to be adopted in order to avoid the spread of such bacteria.
Publication date: Available online 12 December 2019Source: American Journal of Infection ControlAuthor(s): Jiancong Wang, Mouqing Zhou, Fangfei Liu
ConclusionsThis study provides initial perspectives on measles preparedness among Idaho CAHs, despite limited generalizability. Future studies should explore whether self-reported preparedness measures reflect the ability of the CAHs to control measles spread when cases present for care.
A financially troubled Seattle research institute cut back programs, leaving researchers to find new homes for work on infectious diseases like tuberculosis and leprosy.
More News: Academia | Acinetobacter | Antimicrobial Resistance | Babies | Biochemistry | Biotechnology | Burns | Centers for Disease Control and Prevention (CDC) | Children | Cholera | Clostridium Difficile | Department of Health | Ebola | Endemics | Environmental Health | Epidemiology | Gastroenteritis | Genetics | Graduation | Haemophilus Influenzae (Hib) | Haiti Health | Harvard | Health | Health Management | Hospitals | Infectious Diseases | Intensive Care | International Medicine & Public Health | Laboratory Medicine | Lower Endoscopy | Marketing | Medical Devices | Microbiology | MRSA | Multidrug Resistance | Nanotechnology | National Institutes of Health (NIH) | Nurses | Nursing | Outbreaks | Oxford University | Pancreas | Pediatrics | Perinatology & Neonatology | Respiratory Medicine | Salmonella | Science | Staphylococcus Aureus | Strabismus (squint) | Students | Study | Superbugs | Tuberculosis | Universities & Medical Training | University of Washington | Websites | WHO