Illumina Helped the World Fight COVID-19. Now, CEO Francis deSouza Has Monkeypox in His Sights
As chief executive of San Diego-based genomic sequencing company Illumina, Francis deSouza feels well-placed to witness the world’s next great scientific transformation. “I really believe that just like the 20th century was the era of the bit and the digital revolution, the 21st century is likely to be remembered as the era of the genome,” he says. “We’re seeing that play out in terms of genomic-based screening and diagnostics emerging, like Illumina’s offerings, but we’re also seeing the emergence of genomic-based medicine.” DeSouza’s excitement is understandable. Well...
Source: TIME: Health - August 14, 2022 Category: Consumer Health News Authors: John Simons Tags: Uncategorized biztech2030 The Leadership Brief Source Type: news

Antibiotic Stewardship in DermatologyReducing the Risk of Prolonged Antimicrobial Resistance in Skin
Editorial from US perspective summarises latest evidence on resistance development following exposure to systemic antibiotics routinely prescribed in dermatology, discusses clinical consequences of antimicrobial resistance, and strategies to promote antibiotic stewardship. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - August 12, 2022 Category: Consumer Health News Source Type: news

Antimicrobial Resistance Up; Cheaper Accrediting; HIV+ Transplant Antimicrobial Resistance Up; Cheaper Accrediting; HIV+ Transplant
The top 3 things you should know to start your day.3 Things to Know Today (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - July 29, 2022 Category: Consumer Health News Tags: Public Health & Prevention News Source Type: news

Evaluation of droplet digital PCR rapid detection method and precise diagnosis and treatment for suspected sepsis (PROGRESS): a study protocol for a multi-center pragmatic randomized controlled trial.
In this study, a total of 2292 patients with suspected sepsis will be randomly assigned to two arms: the ddPCR group and the control group with a ratio of 3:1. The primary outcome is the diagnostic efficacy, that is, the sensitivity and specificity of the ddPCR assay compared with the synchronous blood culture. Secondary outcomes include the mortality rates and the mean Sequential Organ Failure Assessment (SOFA) score at follow-up time points, the length of stay in the hospital, the time to directed antimicrobial therapy, duration of broad-spectrum antibiotic use, and the EQ-5D-5L score on day 90. Discussion: It is the fir...
Source: Current Awareness Service for Health (CASH) - July 28, 2022 Category: Consumer Health News Source Type: news

Evaluation of droplet digital PCR rapid detection method and precise diagnosis and treatment for suspected sepsis (PROGRESS): a study protocol for a multi-center pragmatic randomized controlled trial
In this study, a total of 2292 patients with suspected sepsis will be randomly assigned to two arms: the ddPCR group and the control group with a ratio of 3:1. The primary outcome is the diagnostic efficacy, that is, the sensitivity and specificity of the ddPCR assay compared with the synchronous blood culture. Secondary outcomes include the mortality rates and the mean Sequential Organ Failure Assessment (SOFA) score at follow-up time points, the length of stay in the hospital, the time to directed antimicrobial therapy, duration of broad-spectrum antibiotic use, and the EQ-5D-5L score on day 90. Discussion: It is the fir...
Source: Current Awareness Service for Health (CASH) - July 28, 2022 Category: Consumer Health News Source Type: news

CDC: Antimicrobial Resistance Surged During COVID-19 Pandemic CDC: Antimicrobial Resistance Surged During COVID-19 Pandemic
In 2020, resistant hospital-related infections and deaths increased at least 15%, CDC reports.Medscape Medical News (Source: Medscape Infectious Diseases Headlines)
Source: Medscape Infectious Diseases Headlines - July 28, 2022 Category: Infectious Diseases Tags: Infectious Diseases News Source Type: news

Is perioperative antibiotic prophylaxis in the case of routine surgical removal of the third molar still justified? A randomized, double-blind, placebo-controlled clinical trial with a split-mouth design
ConclusionsPerioperative administration of oral antibiotics neither revealed additional benefits in patient-related outcome measures nor reduced postoperative complications compared with the placebo group indicated at routine surgical removal of noninflamed wisdom teeth.Clinical relevanceTaking antimicrobial resistance into account, clear recommendations for administering drugs, particularly antibiotics, are critical in oral surgery. (Source: Dental Technology Blog)
Source: Dental Technology Blog - July 26, 2022 Category: Dentistry Source Type: news

Antimicrobial Resistance and Dermatological Ramifications Antimicrobial Resistance and Dermatological Ramifications
Dermatologist are among the most common prescribers of antibiotics, often for prolonged courses. Review strategies to combat antimicrobial resistance as it pertains to dermatology in this paper.The British Journal of Dermatology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 25, 2022 Category: Consumer Health News Tags: Dermatology Journal Article Source Type: news

Antimicrobial resistance control in the emergency department: a need for concrete improvement
Conclusions: Management of AMR varies in German EDs, especially in accordance to hospital size and level of emergency care. IPC seems to receive more attention than AMS. Our data indicate the need for more implementation of regular IPC and AMS training in connection with monitoring and feedback in German EDs. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - July 20, 2022 Category: Consumer Health News Source Type: news

ICYMI: Increase in drug-resistant superbugs during COVID-19 highlights need for policy reforms to address antimicrobial resistance
A newreport released by the U.S. Centers for Disease Control and Prevention (CDC) shows the number of antimicrobial-resistant (AMR) infections rose dramatically during the first year of the COVID-19 pandemic. After years of decline, these drug-resistant infections – often referred to as “superbugs” – caused a 15% increase in hospitalizations and deaths in 2020 alone. Antibiotic and antifungal medicines are critical to the everyday practice of medicine, yet many of our existing medicines may soon no longer be enough. (Source: The Catalyst)
Source: The Catalyst - July 14, 2022 Category: Pharmaceuticals Tags: Research and Development Coronavirus Antimicrobial Resistance Source Type: news

CDC Report Addresses Impact of COVID-19 on Antimicrobial Resistance
WEDNESDAY, July 13, 2022 -- The impact of the COVID-19 pandemic on antimicrobial resistance is addressed in a special report from the U.S. Centers for Disease Control and Prevention. Noting that antimicrobial resistance was one of the main public... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - July 13, 2022 Category: Pharmaceuticals Source Type: news

Africa: WHO Calls for More Vaccines to Combat Antimicrobial Resistance
[WHO] The World Health Organization today released the first-ever report on the pipeline of the vaccines currently in development to prevent infections caused by antimicrobial-resistant (AMR) bacterial pathogens. WHO's analysis points to the need to accelerate trials for AMR related vaccines in late-stage development and maximise the use of existing vaccines. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - July 13, 2022 Category: African Health Source Type: news

Develop more vaccines to combat ‘silent pandemic’ of antimicrobial resistance: WHO
More vaccines must be developed to tackle antimicrobial-resistant (AMR) bacterial pathogens, and countries must make better use of the ones currently available, the World Health Organization (WHO) said on Tuesday.  (Source: UN News Centre - Health, Poverty, Food Security)
Source: UN News Centre - Health, Poverty, Food Security - July 12, 2022 Category: International Medicine & Public Health Source Type: news

Diagnostic Testing for Sepsis: A Systematic Review of Economic Evaluations
Conclusion: Using a diagnostic technique to detect sepsis early on is more cost-effective than standard care. Setting a direct relationship between the implementation of a testing strategy and the reduction of AMR cases, we made several assumptions about the efficacy of antibiotics and the length-of-stay of patients. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - July 11, 2022 Category: Consumer Health News Source Type: news

Boehringer Ingelheim, Evotec and bioM érieux launch Aurobac, a joint venture to fight Antimicrobial Resistance
Boehringer Ingelheim, a leading research-driven biopharmaceutical company, the life science company Evotec SE (Frankfurt Stock Exchange: EVT, MDAX/TecDAX, ISIN: DE0005664809; NASDAQ: EVO) and bioMérieux, a world leader in in vitro diagnostics, have formed a joint venture to create the next generation of antimicrobials along with actionable diagnostics to fight Antimicrobial Resistance (AMR). (Source: World Pharma News)
Source: World Pharma News - July 7, 2022 Category: Pharmaceuticals Tags: Featured Boehringer Ingelheim Business and Industry Source Type: news