Study reveals a connection between the use of NSAIDs and severe C. difficile superbug infections
(Natural News) Antibiotics are known to disrupt the microbial balance in the gut, increasing the risk of getting infected by bacteria such as Clostridium difficile. However, a new study found that even common pain relievers may promote infections caused by C. difficile. C. difficile causes the most common and most dangerous hospital-born infections in the U.S. and around the world. For... (Source: NaturalNews.com)
Source: NaturalNews.com - April 18, 2019 Category: Consumer Health News Source Type: news

Here ’s Everything You Need to Know About Gut Health
It’s hardly news that the gastrointestinal tract is important to human health: It transports food from the mouth to the stomach, converts it into absorbable nutrients and stored energy, and shuttles waste back out of the body. If you don’t properly nourish yourself, you don’t live. It’s that simple. But in recent years, scientists have discovered that the GI system has an even bigger, more complex job than previously appreciated. It’s been linked to numerous aspects of health that have seemingly nothing to do with digestion, from immunity to emotional stress to chronic illnesses, including can...
Source: TIME: Health - March 25, 2019 Category: Consumer Health News Authors: Amanda MacMillan Tags: Uncategorized Research Source Type: news

‘I thought I was going to die’: why patients are no longer pooh-poohing faecal transplants
Bonnie Wortmeyer is one of thousands finding freedom from Clostridium difficile bacteria through faecal microbiota transplantationBonnie Wortmeyer has spent the past few years plagued by ill health. Among the major issues she has had to deal with are a double lung transplant and what she calls her “poo transplant”, which she says changed her life.While recovering from her double lung transplant, Wortmeyer was exposed to numerous courses of antibiotics, which made her susceptible to contracting the Clostridium difficile bacteria. C diff, as it ’s known, is a nasty, life-threatening bacteria which makes lif...
Source: Guardian Unlimited Science - March 24, 2019 Category: Science Authors: Melanie Tait Tags: Health Australia news South Australia Medical research Source Type: news

Antibiotics, PPIs Tied to Higher C. Diff Risk in Hospitalized Children
THURSDAY, March 21, 2019 -- Previous antibiotic exposure and use of proton pump inhibitors (PPIs) may be risk factors for Clostridioides (formerly Clostridium) difficile infection (CDI) in hospitalized pediatric patients, according to a review... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - March 21, 2019 Category: Pharmaceuticals Source Type: news

An At-home Intestinal Screening Test for C. Difficile An At-home Intestinal Screening Test for C. Difficile
An at-home, self-administered sequencing-based clinical intestinal screening test may be useful for identifying the presence of C. difficile in high risk patients.Journal of Medical Case Reports (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 13, 2019 Category: Consumer Health News Tags: Family Medicine/Primary Care Journal Article Source Type: news

NHS Improvement puts onus on CCGs to reduce infection rates
CCGs are to take greater responsibility for reducing clostridium difficile infection (CDI) under measures announced by NHS Improvement. (Source: NHS Networks)
Source: NHS Networks - March 11, 2019 Category: UK Health Source Type: news

Risk of Subsequent Sepsis Within 90 Days After a Hospital Stay by Type of Antibiotic Exposure
We examined the risk of sepsis within 90 days after discharge from a previous hospital stay by type of antibiotic received during the previous stay. Our study identified an increased risk of sepsis within 90 days of discharge among patients with exposure to high-risk antibiotics or increased quantities of antibiotics during hospitalization. Given that a significant proportion of inpatient antimicrobial use may be unnecessary, this study builds on previous evidence suggesting that increased stewardship efforts in hospitals may not only prevent antimicrobial resistance, Clostridium difficile infection, and other adverse effe...
Source: Current Awareness Service for Health (CASH) - February 14, 2019 Category: Consumer Health News Source Type: news

Novel nanoparticle technology to identify healthcare-associated infections receives $1.5 million
(University of Toronto - Leslie Dan Faculty of Pharmacy) Healthcare-associated infections are the fourth leading cause of death in Canada, predicted to move up to second place by 2050. Scientists at the Leslie Dan Faculty of Pharmacy, University of Toronto received $1.5 million in funding from Genome Canada to develop a new nanoparticle sensor technology that will allow hospitals and long-term care facilities to rapidly detect and visually identify highly infectious pathogens including C. difficile, methicillin-resistant S aureus (MRSA), Norovirus and influenza. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 7, 2019 Category: International Medicine & Public Health Source Type: news

Ensuring that Plastic Devices Can Withstand Rigorous Disinfecting Procedures
To try to stem the increasing incidences of healthcare-associated infections (HAIs), hospitals are stepping up their disinfecting protocols on medical devices. But these more-stringent practices that may use either stronger chemicals, or the more frequent use of them, or maybe both, could have harmful effects on some plastic devices, causing them to break, crack, or degrade prematurely. Manufacturers need to understand, from the design stage forward, how their products will be cleaned and then plan to use plastic materials that will stand up to these various disinfecting formulations and procedures. MD+DI spoke with severa...
Source: MDDI - February 1, 2019 Category: Medical Devices Authors: Susan Shepard Tags: Materials Source Type: news

Hospital-acquired Conditions Continue Downward Trend Hospital-acquired Conditions Continue Downward Trend
Adverse drug events, C difficile infections, and other hospital-acquired conditions in the United States declined 13% between 2014 and 2017 but challenges still remain.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - January 31, 2019 Category: Consumer Health News Tags: Hospital Medicine News Source Type: news

Florida man says a fecal transplant cured him of a life-threatening infection
Douglas Lee, from Hillsborough, Florida, developed a C difficile infection - caused by antibiotics killing both good and bad bacteria - after he got his wisdom teeth removed. (Source: the Mail online | Health)
Source: the Mail online | Health - January 22, 2019 Category: Consumer Health News Source Type: news

Ask Well: What Is a Fecal Transplant, and Why Would I Want One?
Fecal transplant is used to treat gut infections and is now being studied as a treatment for obesity, urinary tract infections, irritable bowel syndrome and more. (Source: NYT Health)
Source: NYT Health - January 18, 2019 Category: Consumer Health News Authors: RICHARD KLASCO, M.D. Tags: Feces Transplants Digestive Tract Clostridium Difficile (Bacterium) Bowels Colon Bacteria Source Type: news

Fecal-Microbiota Transplant Beats Antibiotics for Recurrent C Diff Fecal-Microbiota Transplant Beats Antibiotics for Recurrent C Diff
Fecal-microbiota transplantation (FMT) is superior to 10 days of fidaxomicin or vancomycin for resolving recurrent Clostridium difficile infection (CDI), according to results from a randomized open-label clinical trial.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - January 17, 2019 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

Fighting deadly drug resistant bacteria in intestines with new antibiotic
(Flinders University) Clostridium difficile infection (CDI) is a potentially deadly infection in the large intestine most common in people who need to take antibiotics for a long period of time, particularly in Australia's ageing population. But when doses of a new antibiotic called Ramizol were given to hamsters infected with a lethal dose of the bacteria, a significant proportion of hamsters survived the infection. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - January 17, 2019 Category: International Medicine & Public Health Source Type: news

Clostridium difficile Infection | Medscape Clostridium difficile Infection | Medscape
C. difficile infection (CDI) can cause symptoms ranging from diarrhea to life-threatening inflammations of the colon. CDI causes one of the most widespread and serious health care associated infections acquired in a hospital or long-term care facility. (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 14, 2019 Category: Consumer Health News Tags: Resource Center Source Type: news

Clinical Trial Testing Fecal Microbiota Transplant for Recurrent Diarrheal Disease Begins
Clostridium difficile, commonly referred to as C. diff, is a bacterium that infects the colon and can cause diarrhea, fever, and abdominal pain. (Source: National Institutes of Health (NIH) News Releases)
Source: National Institutes of Health (NIH) News Releases - January 14, 2019 Category: American Health Source Type: news

Clinical trial testing fecal microbiota transplant for recurrent diarrheal disease begins
(NIH/National Institute of Allergy and Infectious Diseases) A research consortium recently began enrolling patients in a clinical trial examining whether fecal microbiota transplantation (FMT) by enema--putting stool from a healthy donor in the colon of a recipient--is safe and can prevent recurrent Clostridium difficile-associated disease (CDAD), a potentially life-threatening diarrheal illness. Investigators aim to enroll 162 volunteer participants 18 years or older who have had two or more episodes of CDAD within the previous six months. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - January 14, 2019 Category: Infectious Diseases Source Type: news

Medical News Today: Common pain relievers may worsen C. difficile infection
According to a recent study, certain pain-relieving, anti-inflammatory medication can increase the risks relating to C. difficile infection. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - January 12, 2019 Category: Consumer Health News Tags: Infectious Diseases / Bacteria / Viruses Source Type: news

Are UVC LEDs Driving & #039;Digital Cleaning & #039;?
Hospitals do a lot to kill microbes, but there is a gap in disinfection coverage, said Nick Connelly, application engineer for Crystal IS. “There is a missing layer of protection,” he said, pointing to high-touch surfaces and equipment in healthcare settings such as keyboards. “Consider all the devices being used, including roll-in devices and medication carts.” In addition to using a range of chemical-based disinfectants, hospitals are looking to UV light as a disinfection solution. But some of these UV-light emitting devices, such as mercury lamps, c...
Source: MDDI - January 11, 2019 Category: Medical Devices Authors: Daphne Allen Tags: Sterilization Source Type: news

Nurses at County Durham trust slash C diff infections by 27%
The director of nursing at a trust in North East England has praised staff for helping to reduce the number of patients falling ill with a  Clostridium difficile infection while under their care by almost a third.  (Source: Nursing Times)
Source: Nursing Times - January 9, 2019 Category: Nursing Source Type: news

Hospital nurses in North East slash C diff infections by 27%
The director of nursing at a trust in North East England has praised staff for helping to reduce the number of patients falling ill with a  Clostridium difficile infection while under their care by almost a third.  (Source: Nursing Times)
Source: Nursing Times - January 9, 2019 Category: Nursing Source Type: news

Over-the-counter painkillers like aspirin and ibuprofen may make C.difficile more aggressive  
A study by Vanderbilt University found just 20 per cent of mice treated with the non-steroidal anti-inflammatory drug indomethacin before being exposed to C.difficile survived the infection. (Source: the Mail online | Health)
Source: the Mail online | Health - January 8, 2019 Category: Consumer Health News Source Type: news

How common pain relievers may promote Clostridium difficile infections
(American Society for Microbiology) Clostridium difficile causes the most common and most dangerous hospital-born infections in the United States and around the world. People treated with antibiotics are at heightened risk because those drugs disturb the microbial balance of the gut, but observational studies have also identified a link between severe C. difficile infections and use of NSAIDs, or non-steroidal anti-inflammatory drugs. The study is published in the journal, mBio. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - January 8, 2019 Category: Biology Source Type: news

Association of a label of penicillin allergy with increased risk of MRSA and Clostridium difficile infection: DTB Select summary
This journal article gives summary and context to a matched cohort study, that found people with a documented allergy to penicillin have higher rates of MRSA and Clostridium difficile infection. This was influenced by increased use of alternatives to beta-lactam antibiotics. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - December 28, 2018 Category: Consumer Health News Source Type: news

Hospital-Acquired Infections Are Declining
There were reductions in urinary and surgical infections, but not in pneumonia or C. diff infections. (Source: NYT Health)
Source: NYT Health - December 10, 2018 Category: Consumer Health News Authors: NICHOLAS BAKALAR Tags: Hospitals Infections Clostridium Difficile (Bacterium) Antibiotics Source Type: news

Scientists shed new light on infection process of gastrointestinal pathogen C. difficile
(VIB (the Flanders Institute for Biotechnology)) Scientists from the VIB-UGent Center for Inflammation Research identified the mechanisms by which the bacterial pathogen Clostridium difficile kills intestinal epithelial cells (IECs), thus destroying the protective mucosal barrier of the intestinal tract. The researchers demonstrate the physiological relevance of this process during infection and have published their findings in Nature Communications. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 21, 2018 Category: International Medicine & Public Health Source Type: news

Poo transplant: The ‘oil change’ treatment for your gut - when would you need it?
POO transplants could help to boost the health of the gut, and to avoid symptoms of bacterial infections, including C.difficile ’s nausea, dehydration, diarrhoea and weight loss. When would you need a faecal microbiota transplantation, and how could it boost your immune system? (Source: Daily Express - Health)
Source: Daily Express - Health - November 17, 2018 Category: Consumer Health News Source Type: news

November is C. diff Awareness Month. Mayo Clinic experts available for interviews
ROCHESTER, Minn. ??November is C. diff awareness month, a time to focus on raising awareness about the prevention and treatment of Clostridium Difficile Infections. Mayo Clinic experts are available for interviews. ?C. diff is a bacterial infection that causes symptoms ranging from diarrhea to life-threatening inflammation of the colon,? says Darrell Pardi, M.D., a gastroenterologist [...] (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - November 1, 2018 Category: Research Source Type: news

Clostridium difficile associated disease
This review notes clinical manifestations usually occur on days 4 to 9 of antibiotic (AB) treatment, but may occur up to 8 weeks after discontinuation of ABs. Treatment is started with oral vancomycin or fidaxomicin. It is estimated 5-50% of treated patients have recurrence. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - October 31, 2018 Category: Consumer Health News Source Type: news

Cluster of factors could help predict C. diff
(Ohio State University) A cluster of factors may help predict which patients are likely to develop Clostridioides difficile, a potentially life-threatening disease commonly known as C. difficile or C. diff, a new study has found. And that could help in efforts to prevent infection, according to the researchers. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 24, 2018 Category: International Medicine & Public Health Source Type: news

Think you're allergic to penicillin? Think again
People with penicillin allergies are more likely to get antibiotic-resistant infections such as C.difficile or MRSA, which can be life-threatening - yet 90 per cent are wrongly diagnosed. (Source: the Mail online | Health)
Source: the Mail online | Health - October 22, 2018 Category: Consumer Health News Source Type: news

Hospital Bed Sheets Still Germy Despite Washing
Despite being washed with industrial detergent in high, disinfecting temperatures, hospital sheets still were contaminated with the potentially life-threatening C. difficile bacteria, researchers found. And those sheets spread the bacteria to uncontaminated ones. (Source: WebMD Health)
Source: WebMD Health - October 19, 2018 Category: Consumer Health News Source Type: news

Hospital Bed Sheets Still Germy Despite Washing
FRIDAY, Oct. 19, 2018 -- Even after a thorough cleaning, traces of diarrhea-causing bacteria can remain on hospital bed sheets, researchers report. The new study suggests that linens could transmit Clostridium difficile infections between patients,... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - October 19, 2018 Category: General Medicine Source Type: news

Clostridium difficile Spores Survive Laundering of Sheets
WEDNESDAY, Oct. 17, 2018 -- Clostridium difficile spores are able to survive laundering through a commercial washer extractor, according to a study published online Oct. 16 in Infection Control& Hospital Epidemiology. Joanna Tarrant, Ph.D.,... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - October 18, 2018 Category: Pharmaceuticals Source Type: news

C diff Spores on Bedsheets Survive Hospital Laundering C diff Spores on Bedsheets Survive Hospital Laundering
Typical laundering methods for hospital bedsheets left 60% of Clostridium difficile spores behind; their survival may contribute to future outbreaks, a study has found.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - October 18, 2018 Category: Consumer Health News Tags: Infectious Diseases News Source Type: news

Bacteria that cause diarrhoea survive the high temperatures used in hospital laundries
Researchers from De Montfort University found that C.difficile spores are present at levels sufficient to cause an outbreak even after sheets are washed as set out by the NHS' healthcare laundry policy. (Source: the Mail online | Health)
Source: the Mail online | Health - October 17, 2018 Category: Consumer Health News Source Type: news

Fulminant C. Diff Infection After Cardiac Surgery Fulminant C. Diff Infection After Cardiac Surgery
This paper outlines several independent risk factors for the development of a fulminant C. difficile infection after cardiac surgery.BMC Anesthesiology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 17, 2018 Category: Consumer Health News Tags: Anesthesiology Journal Article Source Type: news

Infectious diarrhea spores survive high temperatures of hospital laundering
(Society for Healthcare Epidemiology of America) Washing contaminated hospital bedsheets in a commercial washing machine with industrial detergent at high disinfecting temperatures failed to remove all traces of Clostridium difficile (C. difficile), a bacteria that causes infectious diarrhea, suggesting that linens could be a source of infection among patients and even other hospitals, according to a study published today in Infection Control& Hospital Epidemiology, the journal of the Society for Healthcare Epidemiology of America. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 16, 2018 Category: International Medicine & Public Health Source Type: news

MRSA, MSSA and Gram-negative bacteraemia and Clostridium difficile infection: annual data for independent sector healthcare organisations
These statistics with accompanying commentary cover rates of MRSA, MSSA, E. coli, P. aeruginosa, Klebsiella spp. bacteraemia and CDI reported by independent sector organisations. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - October 3, 2018 Category: Consumer Health News Source Type: news

The risk of MRSA and C difficile in people with documented'penicillin allergy '
This Medicines Evidence Commentary discusses UK large population-based cohort study that found people with a documented'penicillin allergy'had increased risk of MRSA and C.diff, highlighting importance of ensuring only'true'penicillin allergies are documented, in line with NICE guideline on drug allergy. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - September 28, 2018 Category: Consumer Health News Source Type: news

Guidelines Recommend Fecal-Microbiota Transplant for Recurrent or Refractory C. Diff Guidelines Recommend Fecal-Microbiota Transplant for Recurrent or Refractory C. Diff
New joint guidelines from the British Society of Gastroenterology (BSG) and Healthcare Infection Society (HIS) support the use of fecal-microbiota transplant (FMT) as second-line treatment for recurrent or refractory Clostridium difficile infection (CDI), but not for any other indications.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - September 21, 2018 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

Leapfrog Group Report Shows Hospitals Failing to Eliminate Hospital-Acquired Infections; Medical Laboratories Can Help Providers ’ Antimicrobial Stewardship Programs
Contrary to CMS and Joint Commission programs implemented in 2017 to reduce them, incidents of hospital-acquired infections have risen for the past few years Clinical laboratories and anatomic pathologists know that hospital-acquired infections (HAIs) can be deadly, not just for patients, but for their caregivers and families as well. Even one HAI is too many. […] (Source: Dark Daily)
Source: Dark Daily - September 12, 2018 Category: Laboratory Medicine Authors: Jude Tags: Laboratory Management and Operations Laboratory News Laboratory Operations Laboratory Pathology Management & Operations anatomic pathology antimicrobial stewardship programs C. difficile Castlight Health catheter-associated urinary tract Source Type: news

Medical News Today: What allows C. difficile to survive so well in the gut?
Clostridium difficile causes infections that are hard to treat and that may have negative outcomes for health. What lends this bacterium its resilience? (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - September 12, 2018 Category: Consumer Health News Tags: Infectious Diseases / Bacteria / Viruses Source Type: news

Folding poisons
(University of Freiburg) Researchers show how toxins of the bacterium Clostridium difficile get into cells in the gut. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 11, 2018 Category: International Medicine & Public Health Source Type: news

Clostridium difficile Infection: 5 Things to Know Clostridium difficile Infection: 5 Things to Know
As the most common microbial cause of healthcare-associated infections in US hospitals, clinicians need to have an understanding of C difficile infection. Start with these five key focus areas.Medscape Gastroenterology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 10, 2018 Category: Consumer Health News Tags: Gastroenterology Commentary Source Type: news

Guidance for preventing C. difficile in neonatal intensive care
(Society for Healthcare Epidemiology of America) Newborns require special diagnosis and treatment considerations for an infectious diarrhea known as Clostridioides difficile (C. difficile) infection, according to a new evidence-based white paper published today in Infection Control& Hospital Epidemiology, the journal of the Society for Healthcare Epidemiology of America. The publication is in conjunction with the release of a companion review by the Centers for Disease Control and Prevention's Healthcare Infection Control Practices Advisory Committee (HICPAC). (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - August 30, 2018 Category: Infectious Diseases Source Type: news

Enteric Infections Common in IBD Flares Enteric Infections Common in IBD Flares
About one in six patients experiencing flares of inflammatory bowel disease (IBD) have non-Clostridium difficile enteric infections, according to a new study.Reuters Health Information (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - August 27, 2018 Category: Pathology Tags: Gastroenterology News Source Type: news

Fecal Transplant for Severe Refractory C. Difficile Infection Fecal Transplant for Severe Refractory C. Difficile Infection
This RCT compared the efficacy of two fecal microbiota transplant protocols associated with vancomycin in curing patients with severe Clostridium difficile infection refractory to antibiotics.Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - August 16, 2018 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Mother, 32, escapes death after she caught a potentially killer bug
Rosie Summers, from Surrey, unknowingly caught Clostridium difficile during a stay in hospital to combat a kidney infection. She spent a week in the same hospital fighting for her life against sepsis. (Source: the Mail online | Health)
Source: the Mail online | Health - August 15, 2018 Category: Consumer Health News Source Type: news

C. difficile Tied to Increased Graft Loss in Solid Organ Recipients
Proven infections, antibiotic treatments in past three months tied to increased development of CDI (Source: Pulmonary Medicine News - Doctors Lounge)
Source: Pulmonary Medicine News - Doctors Lounge - August 13, 2018 Category: Respiratory Medicine Tags: Cardiology, Gastroenterology, Infections, Nephrology, Pulmonology, Surgery, Journal, Source Type: news