Cleaning and disinfecting surfaces in hospitals and long-term care facilities for reducing hospital- and facility-acquired bacterial and viral infections: a systematic review
Conclusion: Ten c-RCTs focused on reducing multiple MDROs and/or HAIs and four had significant reductions. Three c-RCTs reported only patient MRSA colonization rates (o ne significant reductions), and one focused on C. difficile (no significant differences). Standardized primary and secondary outcomes are required for future c-RCTs including detailed biofilm cleaning/disinfection interventions. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - April 21, 2022 Category: Consumer Health News Source Type: news
Recently Discharged Patients Pose Risk for Spreading C. Difficile Infection
FRIDAY, April 15, 2022 -- Asymptomatic patients recently discharged from a hospital may be a source of household transmission of Clostridioides difficile infection (CDI), according to a study published in the May issue of Emerging Infectious... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - April 15, 2022 Category: Pharmaceuticals Source Type: news
Asymptomatic C. difficile Carriers May Infect Their Families Asymptomatic C. difficile Carriers May Infect Their Families
Hospitalized asymptomatic C. difficile carriers may infect people they live with after they return home, new research suggests.Medscape Medical News (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - April 14, 2022 Category: Gastroenterology Tags: Infectious Diseases News Source Type: news
The Connection Between IBD and Aging
Inflammatory bowel disease (IBD) has long been thought of as an ailment of middle, or even young, adulthood. The chronic illness—which includes Crohn’s disease and ulcerative colitis, and can cause abdominal pain, diarrhea, bleeding, and decreased quality of life—impacts about 3.1 million people in the U.S. However, it is far from a disease only of the young and middle-aged. More than a quarter of people with IBD are elderly, a figure that is projected to climb to 30% by 2030, according to a 2021 Gastroenterology & Hepatology article.
Even more underappreciated is the growing population of people who ...
Source: TIME: Health - April 8, 2022 Category: Consumer Health News Authors: Katherine Harmon Courage Tags: Uncategorized Disease healthscienceclimate Source Type: news
A comparative analysis of machine learning approaches to predict C. difficile infection in hospitalized patients
Conclusions: MLAs can predict future CDI in hospitalized patients using just 6 hours of data. In clinical practice, a machine-learning based tool may support prophylactic measures, earlier diagnosis, and more timely implementation of infection control measures. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - March 21, 2022 Category: Consumer Health News Source Type: news
What's the Future of Microbiome Therapies in CDI, Cancer? What's the Future of Microbiome Therapies in CDI, Cancer?
Preventive treatments for C difficile recurrence are in phase 3 trials. Oncologists are also investigating microbiome-based differences in treatment response.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - March 18, 2022 Category: Consumer Health News Tags: Gastroenterology News Source Type: news
Aerosolized Hydrogen Peroxide Can Significantly Reduce C. difficile Infections Aerosolized Hydrogen Peroxide Can Significantly Reduce C. difficile Infections
Aerosolized hydrogen peroxide is a new tool in fighting C. difficile in healthcare settings.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - March 18, 2022 Category: Consumer Health News Tags: Infectious Diseases News Source Type: news
Hygienic monitoring in long-term care facilities using ATP, crAssphage, and human noroviruses to direct environmental surface cleaning
Conclusions: Surfaces with high levels of ATP and crAssphage were identified. Quantifying levels of contamination longitudinally and before and after cleaning might enhance infection prevention and control procedures for reducing diarrheal illnesses in LTC facilities. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - March 14, 2022 Category: Consumer Health News Source Type: news
C difficile Vaccine: CLOVER Trial Shows Mixed Results C difficile Vaccine: CLOVER Trial Shows Mixed Results
There ' s mixed news from Pfizer on results from the CLOVER trial of their candidate vaccine for preventing C diff infection.Medscape Medical News (Source: Medscape Internal Medicine Headlines)
Source: Medscape Internal Medicine Headlines - March 8, 2022 Category: Internal Medicine Tags: Infectious Diseases News Source Type: news
What Causes Rectal Prolapse?
Discussion
Rectal prolapse is defined as a herniation of the rectum through the anal verge. In children it is also usually mucosal prolapse and not full thickness. Partial or mucosal prolapse usually is seen as radial folds occurring 1 – 2.5 cm from the anal verge. Full thickness will protrude more than 5 cm. It affects genders equally and occurs most commonly in children under age 4. This is due to vertical course and low position of the anus, looser supporting tissues and less muscular support. These children are more likely to have prolapse but are less likely to have it recur. After age 4 the rectum takes the adu...
Source: PediatricEducation.org - February 28, 2022 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news
C Difficile: New Vancomycin-Resistant Strains Raise Concerns C Difficile: New Vancomycin-Resistant Strains Raise Concerns
The detection of a marked increase in unrecognized strains of C difficile suggests a ' pressing need ' to understand mechanisms.Medscape Medical News (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - February 4, 2022 Category: Gastroenterology Tags: Infectious Diseases News Source Type: news
Spore Therapy Cuts C. Difficile Reinfection by 68% in 8-Week Study Spore Therapy Cuts C. Difficile Reinfection by 68% in 8-Week Study
An experimental 3-day therapy that adds Firmicutes spores to the gut can reduce the risk of C. difficile reinfection by 68%, according to the results from an 8-week phase 3 study.Reuters Health Information (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - January 21, 2022 Category: Gastroenterology Tags: Infectious Diseases News Source Type: news
Subtractive genomic approach toward introduction of novel immunogenic targets against Clostridioides difficile: Thinking out of the box
This study proposes a combination of C. difficile toxoid (Tcd) and surface-exposed proteins such as Acd as a promising vaccine formulation for protection against circulating clinical strains of C. difficile. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - January 17, 2022 Category: Consumer Health News Source Type: news
Vedolizumab Doesn't Increase Risk of C diff in Ulcerative Colitis Vedolizumab Doesn't Increase Risk of C diff in Ulcerative Colitis
Vedolizumab ' s effects in the intestines have led to concerns that the antibody could increase the risk of C difficile infection in patients with ulcerative colitis.Medscape Medical News (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - December 28, 2021 Category: Gastroenterology Tags: Gastroenterology News Source Type: news
Hospital- and System-Wide Interventions for Health Care-Associated Infections: A Systematic Review.
Hospitals face increasing pressure to reduce health care-associated infections (HAI) due to their costs and evidence of preventability. However, there is limited synthesis of evidence regarding interventions that can be successfully implemented hospital- or system-wide. Using Donabedian ' s structure-process-outcome model, we conducted a systematic literature review from 2008 to early 2019, identifying 96 studies with 214 outcomes examining the relationship between hospital- or system-wide interventions and HAIs. This literature ' s methodologic and reporting quality was generally poor. The most common HAIs studied were me...
Source: Current Awareness Service for Health (CASH) - December 14, 2021 Category: Consumer Health News Source Type: news
