Additional prophylactic antibiotics do not decrease surgical site infection rates in pediatric patients with appendicitis and cholecystitis
Conclusion: In pediatric patients receiving treatment antibiotics for acute intraabdominal infection, additional prophylactic antibiotics may not reduce SSIs. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - November 12, 2021 Category: Consumer Health News Source Type: news

A Pill for C difficile Works by Increasing Microbiome Diversity A Pill for C difficile Works by Increasing Microbiome Diversity
Freeze-dried human stool may offer advantages for the treatment of C difficile infections.Medscape Medical News (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - October 25, 2021 Category: Gastroenterology Tags: Gastroenterology News Source Type: news

Surveillance for Healthcare-Associated Infections: Hospital-Onset Adult Sepsis Events Versus Current Reportable Conditions
Conclusions CDC ' s HO-ASE definition detects many serious nosocomial infections missed by currently reportable HAIs. HO-ASE surveillance could increase the efficiency and clinical significance of surveillance while identifying new targets for prevention. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - October 8, 2021 Category: Consumer Health News Source Type: news

Antimicrobial stewardship and infection prevention interventions targeting healthcare-associated Clostridioides difficile and carbapenem-resistant Klebsiella pneumoniae infections: a scoping review
Conclusion: This scoping review identified the AMS and IP interventions targeting C. difficile and CRKP in healthcare settings and described their key outcomes. The application of behaviour change principles in AMS and IP interventions appears to be limited. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - September 10, 2021 Category: Consumer Health News Source Type: news

Fecal Transplants: a New Treatment for IBD
Linda Ann Sasser has had ulcerative colitis since she was 20, but it wasn’t until May 2019, about 30 years later, that her condition hit a low point: not only did she have a major flare-up of chronic inflammatory bowel disease (IBD), but on top of it, she had Clostridioides difficile (or C. diff), a highly contagious bacterial infection that causes severe diarrhea and inflammation of the colon. “I became really, really sick with bloody diarrhea 30 times a day and chronic stomach pain,” Sasser says. While hospitalized for 12 days, she was given oral steroid medications, which didn’t help, then IV ste...
Source: TIME: Health - September 9, 2021 Category: Consumer Health News Authors: Stacey Colino Tags: Uncategorized Disease feature Source Type: news

Costs Associated with the Treatment of Clostridioides Difficile Infections
Background: Clostridioides difficile , as the main cause of infectious diarrhoea in hospitalised patients, is a considerable challenge for medical personnel (hospital environment) who have direct contact with the patient, as well as being of interest to public health specialists. Financial issues related to the occurrence of the above-mentioned micro-organism are being increasingly raised. Due to the scale of the phenomenon, we are beginning to pay attention to the significant system costs caused by the diagnosis and treatment of CDI infection and its complications. Studies indicate that the nosocomial infection of C. diff...
Source: Current Awareness Service for Health (CASH) - August 12, 2021 Category: Consumer Health News Source Type: news

Minimising Clostridioides difficile and Gram-negative Bloodstream Infections, NHS England
This document sets the thresholds for each trust, together with the methodology used to identify and minimise rates of both Clostridioides difficile (C. difficile) and Gram-negative bloodstream infections. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - August 10, 2021 Category: Consumer Health News Source Type: news

Secondary Oral Vancomycin PPX Reduces Recurrent C Diff Infection Secondary Oral Vancomycin PPX Reduces Recurrent C Diff Infection
Pediatric patients with C difficile infection have a significantly lower risk of recurrence within 8 weeks of antibiotic exposure when they receive secondary oral vancomycin prophylaxis, a small study suggests.Reuters Health Information (Source: Medscape Infectious Diseases Headlines)
Source: Medscape Infectious Diseases Headlines - August 2, 2021 Category: Infectious Diseases Tags: Gastroenterology News Source Type: news

Antimicrobial prescribing for C. difficile infection
NICE has updated its antimicrobial prescribing guideline for C. difficile, which sets out a strategy for managing infection in adults, young people and children aged 72 hours and over, in community and hospital settings. (Source: NHS Networks)
Source: NHS Networks - July 28, 2021 Category: UK Health Source Type: news

C Diff Eradication Not Necessary for Clinical Cure C Diff Eradication Not Necessary for Clinical Cure
The findings support existing guidance not to test for presence of C difficile after treatment if the patient is asymptomatic.Medscape Medical News (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - July 26, 2021 Category: Gastroenterology Tags: Infectious Diseases News Source Type: news

First Light Diagnostics Receives FDA Clearance for its Rapid Clostridiodes difficile Test on the MultiPath(R) Analyzer
First FDA cleared product based on the Company's proprietary MultiPath technology CHELMSFORD, Mass., July 20, 2021 -- (Healthcare Sales & Marketing Network) -- First Light Diagnostics is developing and commercializing breakthrough automated diagnostic ... Diagnostics, FDA First Light Diagnostics, SensiTox, C. difficile test, Clostridium difficile (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - July 20, 2021 Category: Pharmaceuticals Source Type: news

Haem is crucial for medium-dependent metronidazole resistance in clinical isolates of Clostridioides difficile
Conclusions: Our data demonstrate that haem is crucial for medium-dependent metronidazole resistance in C. difficile. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - July 16, 2021 Category: Consumer Health News Source Type: news

Guidance Updated for Managing C. difficile Infection in Adults
MONDAY, July 12, 2021 -- Use of fidaxomicin and bezlotoxumab is suggested in specific cases for management of Clostridioides difficile infection (CDI), according to a clinical practice guideline update issued by the Infectious Diseases Society of... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - July 12, 2021 Category: Pharmaceuticals Source Type: news

Microbiome startup Seres Therapeutics expands Nestl é Health partnership
As microbiome startup Seres Therapeutics gets ready to bring its C. difficile treatment to the FDA, it has expanded its partnership with Nestl é Health, which is providing Seres with up to $500 million to commercialize the drug. $MCRB (Source: bizjournals.com Health Care:Physician Practices headlines)
Source: bizjournals.com Health Care:Physician Practices headlines - July 2, 2021 Category: American Health Authors: Rowan Walrath Source Type: news

New Guideline for Prevention, Diagnosis, and Treatment of C diff New Guideline for Prevention, Diagnosis, and Treatment of C diff
New guidelines on C difficile from the American College of Gastroenterology offer recommendations on prevention, diagnosis, and treatment, along with guidance for special populations.Medscape Medical News (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - June 25, 2021 Category: Gastroenterology Tags: Gastroenterology News Source Type: news