The Latest Poop On Fecal Transplants Vs. Antibiotics For C. Difficile Diarrhea
How can more poop actually help with severe diarrhea? Well, when the diarrhea is caused by the antibiotic-resistant bacteria Clostridium difficile, a poop transplant may help get to the bottom of the problem. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - June 2, 2018 Category: Pharmaceuticals Authors: Bruce Y. Lee, Contributor Source Type: news
Fecal Transplants vs. Antibiotics. The Test.
Instead of waiting until antibiotics have failed before trying fecal transplants, researchers tried giving the fecal bacteria first. (Source: NYT Health)
Source: NYT Health - June 2, 2018 Category: Consumer Health News Authors: GINA KOLATA Tags: Feces Antibiotics Transplants Digestive Tract Bacteria Clostridium Difficile (Bacterium) Clinical Trials Infections Colitis New England Journal of Medicine University of Oslo Source Type: news
Antibiotics Didn ’ t Cure Their Infections. Fecal Bacteria Did.
In a small study, fecal transplants ended a persistent, dangerous gut infection just as effectively as drugs. (Source: NYT Health)
Source: NYT Health - June 2, 2018 Category: Consumer Health News Authors: GINA KOLATA Tags: Feces Antibiotics Transplants Digestive Tract Bacteria Clostridium Difficile (Bacterium) Clinical Trials Infections Colitis New England Journal of Medicine University of Oslo Source Type: news
UCI-Harvard research may help combat the deadly gastrointestinal infection C. diff
(University of California - Irvine) Clostridium difficile infection is the most common cause of antibiotic-associated diarrhea in developed countries. Researchers have discovered how the C. diff toxin B recognizes the human Frizzled protein, the receptor it uses to invade intestinal cells and lead to deadly gastrointestinal infections. The findings, published in Science, could pave the way for new C. diff antitoxins and also show potential for the development of novel anti-cancer drugs. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 11, 2018 Category: International Medicine & Public Health Source Type: news
Structural basis for recognition of frizzled proteins by Clostridium difficile toxin B
Clostridium difficile infection is the most common cause of antibiotic-associated diarrhea in developed countries. The major virulence factor, C. difficile toxin B (TcdB), targets colonic epithelia by binding to the frizzled (FZD) family of Wnt receptors, but how TcdB recognizes FZDs is unclear. Here, we present the crystal structure of a TcdB fragment in complex with the cysteine-rich domain of human FZD2 at 2.5-angstrom resolution, which reveals an endogenous FZD-bound fatty acid acting as a co-receptor for TcdB binding. This lipid occupies the binding site for Wnt-adducted palmitoleic acid in FZDs. TcdB binding locks th...
Source: ScienceNOW - May 10, 2018 Category: Science Authors: Chen, P., Tao, L., Wang, T., Zhang, J., He, A., Lam, K.-h., Liu, Z., He, X., Perry, K., Dong, M., Jin, R. Tags: Biochemistry, Microbiology reports Source Type: news
Probiotics can prevent bacterial diarrhoea in hospital patients receiving antibiotics
This NIHR Signal gives commentary on an updated Cochrane Review. It provides new evidence suggesting probiotics may be beneficial for hospitalised patients at risk of C. Difficile infection. Probiotics may be suitable for use in high-risk patients needing antibiotics, for example, older adults with underlying illness. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - May 9, 2018 Category: Consumer Health News Source Type: news
Probiotics Effective for Primary Prevention of C. Diff Probiotics Effective for Primary Prevention of C. Diff
Probiotics are effective for preventing Clostridium difficile infection (CDI) in patients treated with antibiotics, according to findings from two research groups.Reuters Health Information (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 7, 2018 Category: Consumer Health News Tags: Gastroenterology News Source Type: news
New Help for Managing Clostridium difficile Infection New Help for Managing Clostridium difficile Infection
New guidelines from IDSA/SHEA highlight best practices for treatingC difficile infection. Dr David Johnson provides insight for all providers who must be cognizant of this widespread problem.Medscape Gastroenterology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - April 26, 2018 Category: Consumer Health News Tags: Gastroenterology Commentary Source Type: news
Probiotics useful in the fight against infection prevention
(Society for Healthcare Epidemiology of America) Probiotics may be a relatively safe, simple, and low-cost solution for preventing Clostridium difficile infections (CDI) in hospital settings, according to two studies published today in Infection Control& Hospital Epidemiology, the journal of the Society for Healthcare Epidemiology of America. Both studies show that treating patients who received antibiotics with multi-strain probiotics, cut down on CDI incidence rates over time. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - April 26, 2018 Category: Infectious Diseases Source Type: news
Artificial Differences in C difficile Infection Rates Artificial Differences in C difficile Infection Rates
This report looks at how testing methods and frequency may have impacted the reported rates of C difficile infection.Emerging Infectious Diseases (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - April 19, 2018 Category: Consumer Health News Tags: Infectious Diseases Journal Article Source Type: news
C. Difficile Risk Higher With Stoma Reversal Versus Colectomy
WEDNESDAY, April 18, 2018 -- Patients who undergo elective stoma reversal have a higher incidence of postoperative Clostridium difficile infection versus patients who undergo elective colectomy, according to a study published in the May issue of... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - April 18, 2018 Category: Pharmaceuticals Source Type: news
Study finds NYC mice may be hotbeds of antibiotic-resistant bacteria
Apartment-dwelling rodents all over the city carry treatment-resistant C. difficile, E. coli, Shigella and Salmonella that can be transmitted to residents, the team found. (Source: the Mail online | Health)
Source: the Mail online | Health - April 17, 2018 Category: Consumer Health News Source Type: news
Study finds NYC mice are hotbeds of antibiotic-resistant bacteria
Apartment-dwelling rodents all over the city carry treatment-resistant C. difficile, E. coli, Shigella and Salmonella that can be transmitted to residents, the team found. (Source: the Mail online | Health)
Source: the Mail online | Health - April 17, 2018 Category: Consumer Health News Source Type: news
NYC Mice Are Carrying Antibiotic-Resistant Germs
People who live in cities are used to the company of furry vermin. But a new study reveals that mice and men may be sharing much more than just living quarters.
In a study published in the journal mBio, researchers led by Dr. Ian Lipkin, professor of epidemiology at the Mailman School of Public Health at Columbia University, studied the gut microbes of 416 mice collected from mostly residential buildings all over New York City. Lipkin and his team did a thorough genetic analysis of the microbes they extracted from the feces of the mice, and found that they contained a number of disease-causing bacteria.
Nearly 40% of the ...
Source: TIME: Health - April 17, 2018 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized Bacteria healthytime Source Type: news
Clostridium difficile Infection: Prevention and Treatment Clostridium difficile Infection: Prevention and Treatment
This review provides evidence-based pointers on the prevention and treatment of C. difficile infection. What are the options, and how effective are they?American Family Physician (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - April 5, 2018 Category: Consumer Health News Tags: Family Medicine/Primary Care Journal Article Source Type: news
