New Antibiotic Slays Deadly Superbug in Early Trial
THURSDAY, Jan. 4, 2024 -- Researchers report that a new type of antibiotic has proved its mettle against a deadly superbug. Acinetobacter baumannii, a bacteria goes by the nickname CRAB, can trigger serious infections in the lungs, urinary tract... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - January 4, 2024 Category: General Medicine Source Type: news

Scientists hail new antibiotic that can kill drug-resistant bacteria
Zosurabalpin has defeated strains of pneumonia and sepsis in mice, raising hopes for human trialsScientists have discovered an entirely new class of antibiotic that appears to kill one of three bacteria considered to pose thegreatest threat to human health because of their extensive drug-resistance.Zosurabalpin defeated highly drug-resistant strains ofCarbapenem-resistant Acinetobacter baumannii (Crab) in mouse models of pneumonia and sepsis, and was being tested in human trials.Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - January 3, 2024 Category: Science Authors: Linda Geddes Science correspondent Tags: Infectious diseases Medical research Antibiotics Society Science Microbiology World news Source Type: news

Might Bacteria be Used to Identify Cancer Cells? Some Researchers Using Synthetic Biology and Genetic Engineering Techniques Say ‘Yes’
Cellular healthcare is an approach that goes beyond clinical laboratory testing to identify the location of specific cancer cells and aid in treatment decisions Advances in synthetic biology and genetic engineering are leading to development of bacterial biosensors that could eventually aid pathologists and clinical laboratories in diagnosis of many types of cancers. One recent […] The post Might Bacteria be Used to Identify Cancer Cells? Some Researchers Using Synthetic Biology and Genetic Engineering Techniques Say ‘Yes’ appeared first on Dark Daily. (Source: Dark Daily)
Source: Dark Daily - November 8, 2023 Category: Laboratory Medicine Authors: Jillia Schlingman Tags: Laboratory Pathology Laboratory Resources Laboratory Testing Molecular Diagnostics, Genetic Testing, Whole Gene Sequencing Precision Medicine A. baylyi Acinetobacter baylyi anatomic pathology bacterial biosensors CATCH Cellular Assay f Source Type: news

IDSA: A. Baumannii, C. Auris Common for Recipients of Mechanical Ventilation
THURSDAY, Oct. 19, 2023 -- For patients receiving mechanical ventilation, Acinetobacter baumannii and Candida auris are common, with an increased likelihood of colonization among those in long-term care facilities versus acute care hospitals,... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - October 19, 2023 Category: Pharmaceuticals Source Type: news

Superbugs Common in Patients on Mechanical Ventilation
(MedPage Today) -- BOSTON -- Acinetobacter baumannii and Candida auris were common among patients receiving mechanical ventilation in both acute care hospitals and long-term care facilities, particularly the latter, according to data from the... (Source: MedPage Today Infectious Disease)
Source: MedPage Today Infectious Disease - October 12, 2023 Category: Infectious Diseases Source Type: news

McMaster University Uses AI Algorithm, Machine Learning to Find Antibiotic That Neutralizes Common Antimicrobial Resistant Superbug
Further development of this novel technology could result in new, more sensitive assays for clinical laboratories to use in the effort to improve antimicrobial stewardship in hospitals Researchers at McMaster University in Ontario, Canada, have used artificial intelligence (AI) to identify a potential antibiotic that neutralizes the drug-resistant bacteria Acinetobacter baumannii, an antibiotic resistant pathogen […] The post McMaster University Uses AI Algorithm, Machine Learning to Find Antibiotic That Neutralizes Common Antimicrobial Resistant Superbug appeared first on Dark Daily. (Source: Dark Daily)
Source: Dark Daily - June 28, 2023 Category: Laboratory Medicine Authors: swallask Tags: Laboratory News Laboratory Pathology Laboratory Resources Laboratory Testing Source Type: news

Canadian researchers use AI to find a possible treatment for bacteria superbug
A group involving McMaster University scientists have used artificial intelligence to find a treatment for Acinetobacter baumannii, a deadly superbug that, until now, was resistant to previously known antibiotics. (Source: CBC | Health)
Source: CBC | Health - May 31, 2023 Category: Consumer Health News Tags: Radio/The Current Source Type: news

New Therapy OK'd for Drug-Resistant Pneumonia
(MedPage Today) -- The FDA has approved sulbactam-durlobactam (Xacduro) for healthcare-acquired bacterial pneumonia caused by certain strains of Acinetobacter baumannii-calcoaceticus complex (A. baumannii), the agency announced late on Tuesday... (Source: MedPage Today Public Health)
Source: MedPage Today Public Health - May 24, 2023 Category: American Health Source Type: news

FDA Approves Xacduro (sulbactam and durlobactam) for the Treatment of Serious Infections Caused by Acinetobacter
WALTHAM, Mass.--(BUSINESS WIRE)--May 23, 2023-- Innoviva Specialty Therapeutics, a subsidiary of Innoviva, Inc. (Nasdaq: INVA), today announced that the U.S. Food and Drug Administration (FDA) approved Xacduro® (sulbactam for injection;... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - May 23, 2023 Category: Drugs & Pharmacology Source Type: news

The emergence of multidrug-resistant bacteria causing healthcare-associated infections in COVID-19 patients - a retrospective multi-centre study
Introduction: We evaluated the prevalence, aetiologies and antibiotic resistance patterns of bacterial infections in hospitalized patients with laboratory-confirmed SARS-CoV-2. We also investigated comorbidities, risk factors, and the mortality rate in COVID-19 patients with bacterial infections. Methods: This retrospective observational study evaluated medical records of 7249 randomly selected patients with COVID-19 admitted to three clinical centres between January 1 2021 and February 16, 2022. A total of 6478 COVID-19 patients met the eligibility criteria for analysis. Results: The mean age of the patients with SARS-CoV...
Source: Current Awareness Service for Health (CASH) - May 16, 2023 Category: Consumer Health News Source Type: news

FDA Panel to Weigh Limited Data on Combo for Healthcare-Acquired Pneumonia
(MedPage Today) -- Data from small trials will determine whether an FDA advisory panel recommends the agency approve sulbactam‐durlobactam for hospital-acquired and ventilator-associated bacterial pneumonia (HABP/VABP) caused by Acinetobacter... (Source: MedPage Today Public Health)
Source: MedPage Today Public Health - April 14, 2023 Category: American Health Source Type: news

FDA Rationale for Polymyxin Breakpoints for Enterobacterales, Pseudomonas aeruginosa, and Acinetobacter spp.
Rationale for Polymyxin Breakpoints for Enterobacterales, Pseudomonas aeruginosa, and Acinetobacter spp. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - January 17, 2023 Category: Drugs & Pharmacology Authors: FDA Source Type: news

Study Shows Huge Increase in Bloodstream Infections in Europe During First Two Years of COVID-19 Pandemic
Clinical laboratory data was key in identifying antibiotic-resistant bacteria responsible for surge in BSIs in hospitals and other healthcare facilities in 2020 and 2021 Clinical laboratory data compiled by the European Antimicrobial Resistance Surveillance Network (EARS-Net) shows that a massive increase in bloodstream infections (BSIs) occurred among EU nations during the first two years of […] The post <strong>Study Shows Huge Increase in Bloodstream Infections in Europe During First Two Years of COVID-19 Pandemic</strong> appeared first on Dark Daily. (Source: Dark Daily)
Source: Dark Daily - January 11, 2023 Category: Laboratory Medicine Authors: Jillia Schlingman Tags: International Laboratory News Laboratory Instruments & Laboratory Equipment Laboratory Pathology Laboratory Testing Acinetobacter AMR anatomic pathology antimicrobial resistance antimicrobial susceptibility testing bloodstream infection Source Type: news

Some bloodstream infection bacteria grew resistant to last-resort drugs in 2020
By Natalie Grover LONDON (Reuters) -Increased drug resistance in bacteria causing bloodstream infections, including against last-resort antibiotics, was seen in the first year of the coronavirus pandemic, a World Health Organization report based on data from 87 countries in 2020 showed. The…#gsk #merck #klebsiella #whoglobalantimicrobialresistancesurv #thomascueni #smallbiopharmacompanies #amr #nataliegrover #acinetobacter #internationalassociationofpharmaceuti (Source: Reuters: Health)
Source: Reuters: Health - December 9, 2022 Category: Consumer Health News Source Type: news

Emergence of High Antimicrobial Resistance among Critically Ill Patients with Hospital-Acquired Infections in a Tertiary Care Hospital.
Conclusions: The current study describes the high antibiotic resistance patterns in various hospital units that need extra legislation to prevent healthcare providers from misprescription and overuse of antibiotics. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - November 15, 2022 Category: Consumer Health News Source Type: news