FDA Rationale for Polymyxin Breakpoints for Enterobacterales, Pseudomonas aeruginosa, and Acinetobacter spp.
Rationale for Polymyxin Breakpoints for Enterobacterales, Pseudomonas aeruginosa, and Acinetobacter spp. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - January 17, 2023 Category: Drugs & Pharmacology Authors: FDA Source Type: news
Study Shows Huge Increase in Bloodstream Infections in Europe During First Two Years of COVID-19 Pandemic
Clinical laboratory data was key in identifying antibiotic-resistant bacteria responsible for surge in BSIs in hospitals and other healthcare facilities in 2020 and 2021 Clinical laboratory data compiled by the European Antimicrobial Resistance Surveillance Network (EARS-Net) shows that a massive increase in bloodstream infections (BSIs) occurred among EU nations during the first two years of […]
The post <strong>Study Shows Huge Increase in Bloodstream Infections in Europe During First Two Years of COVID-19 Pandemic</strong> appeared first on Dark Daily. (Source: Dark Daily)
Source: Dark Daily - January 11, 2023 Category: Laboratory Medicine Authors: Jillia Schlingman Tags: International Laboratory News Laboratory Instruments & Laboratory Equipment Laboratory Pathology Laboratory Testing Acinetobacter AMR anatomic pathology antimicrobial resistance antimicrobial susceptibility testing bloodstream infection Source Type: news
Some bloodstream infection bacteria grew resistant to last-resort drugs in 2020
By Natalie Grover LONDON (Reuters) -Increased drug resistance in bacteria causing bloodstream infections, including against last-resort antibiotics, was seen in the first year of the coronavirus pandemic, a World Health Organization report based on data from 87 countries in 2020 showed. The…#gsk #merck #klebsiella #whoglobalantimicrobialresistancesurv #thomascueni #smallbiopharmacompanies #amr #nataliegrover #acinetobacter #internationalassociationofpharmaceuti (Source: Reuters: Health)
Source: Reuters: Health - December 9, 2022 Category: Consumer Health News Source Type: news
Emergence of High Antimicrobial Resistance among Critically Ill Patients with Hospital-Acquired Infections in a Tertiary Care Hospital.
Conclusions: The current study describes the high antibiotic resistance patterns in various hospital units that need extra legislation to prevent healthcare providers from misprescription and overuse of antibiotics. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - November 15, 2022 Category: Consumer Health News Source Type: news
Novel Siderophore Cephalosporin Nets Promising Results in Tough-to-Treat CRAB
(MedPage Today) -- WASHINGTON – Cefiderocol (Fetroja) may be a viable targeted-therapy option in critically ill patients with carbapenem-resistant Acinetobacter baumannii infections (CRAB), according to the ongoing PROVE trial.
In the real... (Source: MedPage Today Infectious Disease)
Source: MedPage Today Infectious Disease - October 24, 2022 Category: Infectious Diseases Source Type: news
Clinical implementation of routine whole-genome sequencing for hospital infection control of multi-drug resistant pathogens
Conclusions: Implementation of routine WGS for MDR pathogens in clinical laboratories is feasible and can enable targeted infection prevention and control interventions. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - September 8, 2022 Category: Consumer Health News Source Type: news
Microbial bioburden of inpatient and outpatient areas beyond patient hospital rooms.
Conclusions: Surfaces in hospitals outside patient rooms and in outpatient facilities are frequently contaminated with healthcare-associated pathogens. Improvements in cleaning and disinfection practices are needed to reduce contamination. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - August 19, 2022 Category: Consumer Health News Source Type: news
Viability of hospital pathogens on mobile phone
Conclusions: The extended duration of bacterial viability indicates the ability for pathogens to persist on a device and remain viable long enough to be transmitted to new areas both within the hospital and out to the community. Mobile phone decontamination should occur in combination of hand hygi ene. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - July 20, 2022 Category: Consumer Health News Source Type: news
Cleaning and disinfecting surfaces in hospitals and long-term care facilities for reducing hospital- and facility-acquired bacterial and viral infections: a systematic review
Conclusion: Ten c-RCTs focused on reducing multiple MDROs and/or HAIs and four had significant reductions. Three c-RCTs reported only patient MRSA colonization rates (o ne significant reductions), and one focused on C. difficile (no significant differences). Standardized primary and secondary outcomes are required for future c-RCTs including detailed biofilm cleaning/disinfection interventions. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - April 21, 2022 Category: Consumer Health News Source Type: news
Machine-learning based prediction of prognostic risk factors in patients with invasive candidiasis infection and bacterial bloodstream infection: a singled centered retrospective study.
Conclusion: Our results showed that the most common candida and bacteria infections were caused by Candida parapsilosis and Acinetobacter baumannii, respectively. The main predictors of death prognosis are serum creatinine level, age, length of stay, stay in ICU during hospitalisation, serum albumin level, CRP, leukocyte count, neutrophil count, PCT and total bilirubin level. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - March 2, 2022 Category: Consumer Health News Source Type: news
A five-component infection control bundle to permanently eliminate a carbapenem-resistant Acinetobacter baumannii spreading in an intensive care unit
Conclusion: A five-component bundle of continuous hand hygiene improvement, extended sampling at screening including the environment, universal contact precautions and a novel cycling radical environmental cleaning and disinfection procedure proved to be effective for permanently eliminating CRAB spreading within the ICU. Cohorting, admission restriction or ICU closure were avoided. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - September 10, 2021 Category: Consumer Health News Source Type: news
MoWa: A Disinfectant for Hospital Surfaces Contaminated With Methicillin-Resistant Staphylococcus aureus (MRSA) and Other Nosocomial Pathogens
Conclusions: MoWa kills planktonic and biofilms made by MRSA and MSSA strains and showed great efficacy to disinfect MRSA-, and MSSA-contaminated, surfaces and surfaces contaminated with other important nosocomial pathogens. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - August 12, 2021 Category: Consumer Health News Source Type: news
Announcing the re-annotation of RefSeq genome assemblies for E. coli and four other species!
We have re-annotated all RefSeq genomes for Escherichia coli, Mycobacterium tuberculosis, Bacillus subtilis, Acinetobacter pittii, and Campylobacter jejuni using the most recent release of PGAP. You will find that more genes now have gene symbols (e.g. recA). Your feedback indicated that the lack of symbols was an impediment to comparative analysis, so we hope that this improvement … Continue reading Announcing the re-annotation of RefSeq genome assemblies for E. coli and four other species! → (Source: NCBI Insights)
Source: NCBI Insights - June 23, 2021 Category: Databases & Libraries Authors: NCBI Staff Tags: What's New Genome annotation Genome assemblies NCBI Prokaryotic Genome Annotation Pipeline (PGAP) Reference genome RefSeq Source Type: news
Increase in Hospital-Acquired Carbapenem-Resistant Acinetobacter baumannii Infection and Colonization in an Acute Care Hospital During a Surge in COVID-19 Admissions - New Jersey, February-July 2020
This report describes a cluster of 34 carbapenem-resistant Acinetobacter baumannii cases in a New Jersey hospital that peaked during a surge in COVID-19 hospitalizations. (Source: CDC Morbidity and Mortality Weekly Report)
Source: CDC Morbidity and Mortality Weekly Report - December 3, 2020 Category: American Health Tags: Carbapenem Resistant Enterobacteriaceae (CRE) MMWR Morbidity & Mortality Weekly Report COVID-19 Coronavirus Disease 2019 Source Type: news
Infections in Pediatric Burn Patients: An Analysis of One Hundred Eighty-One Patients
This study was performed at the Pediatric Burn Unit of Ankara Child Health and Diseases Hematology Oncology Training and Research Hospital during the period between January 2014 and June 2017. The patients were evaluated for age, sex, burn etiology, burned body surface area (BSA), the presence of inhalation injury, sepsis, positive cultures, the micro-organisms cultured samples, and septic focus. Result(s): A total of 181 patients were included in the study. The most common cause of burns was scalds in 120 patients (66.3%). Forty-one patients (22.7%) developed health-care-associated infection and sepsis. Gram-negative micr...
Source: Current Awareness Service for Health (CASH) - June 4, 2020 Category: Consumer Health News Source Type: news
