Real-World Registry on the Pharmacotherapy of Multiple Myeloma and Associated Renal and Pulmonary Impairments in the Greater Gulf Region: Protocol for a Retrospective Real-World Data Study
CONCLUSIONS: Although MM is a predominant hematological disease, data on its prevalence and patients' characteristics in the Greater Gulf region are scarce. Therefore, this study will give us real-world insights into disease characteristics and various management approaches of patients with MM in the Greater Gulf region.INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): DERR1-10.2196/49861.PMID:38657230 | DOI:10.2196/49861 (Source: Cancer Control)
Source: Cancer Control - April 24, 2024 Category: Cancer & Oncology Authors: Abdulnaser Nourallah Abdulrahman Alshehri Ayman Alhejazi Binyam Usman Ghada ElGohary Hafiz Malhan Ibraheem Motabi Khalil Al Farsi Mohammed Alshuaibi Mustaqeem Siddiqui Rasha Ghonema Ruba Yasin Taha Tarek Abouzeid Wesam Ahmed Mohanad Diab Ahmad Alhuraiji M Source Type: research
Variations in reporting of nurse involvement in end-of-life practices in intensive care units worldwide (ETHICUS-2): A prospective observational study
CONCLUSION: There is large variability in nurse involvement in end-of-life decision-making in the ICU. The most concerning findings were that in some regions, according to physicians, nurses were not involved in EOL decisions and did not initiate the decision-making process. There is a need to develop the collaboration between nurses and physicians. Nurses have valuable contributions for best possible patient-centered decisions and should be respected as important parts of the interdisciplinary team.TWEETABLE ABSTRACT: Wide global differences were found in nurse end of life decision involvement, with low involvement in Nor...
Source: Pain Physician - April 24, 2024 Category: Anesthesiology Authors: Julie Benbenishty Freda DeKeyser Ganz Alexandre Lautrette Ulrich Jaschinski Avneep Aggarwal Eldar S øreide Manfred Weiss Knut Dybwik Elif Ay şe Çizmeci Roberto Carlos Miranda Ackerman Bel én Estebanez-Montiel Bara Ricou Annette Robertsen Charles L Spr Source Type: research
Blood Pressure Control and Associated Factors among Hypertension Comorbid Type 2 Diabetic Patients in Southeast Ethiopia
CONCLUSION: Uncontrolled hypertension was found to be high among hypertension comorbid type 2 diabetic patients. Patients' adherence to antihypertensive medication, physical activity, and alcohol abstinence should be maximized. Loss of weight is also crucial, as is the early detection and management of comorbidities.PMID:38655153 | PMC:PMC11039015 | DOI:10.1155/2024/6668436 (Source: International Journal of Hypertension)
Source: International Journal of Hypertension - April 24, 2024 Category: Cardiology Authors: Fikreab Desta Selamawit Mengesha Fanuel Belayneh Demelash Woldeyohannes Yohannes Tekalegn Demisu Zenbaba Biniyam Sahiledengle Dejene Hailu Source Type: research
Factors Associated With Margin Positivity After Lung Resection Surgery
CONCLUSION: In conclusion, there was no difference in margin positivity when comparing robotic and VATS resection, however, open resection had increased rates of margin positivity. Increasing tumor size, clinical stage, squamous and adenosquamous histologies, male sex, and patients undergoing a wedge resection were all associated with increased rates of margin positivity.PMID:38658271 | DOI:10.1016/j.cllc.2024.03.007 (Source: Clinical Lung Cancer)
Source: Clinical Lung Cancer - April 24, 2024 Category: Cancer & Oncology Authors: Hamza Rshaidat Gregory L Whitehorn Micaela Collins Shale J Mack Jonathan Martin Tyler R Grenda Nathaniel R Evans Olugbenga T Okusanya Source Type: research
Effects of a single subanesthetic dose of esketamine on postoperative subthreshold depressive symptoms in patients undergoing unilateral modified radical mastectomy: a randomised, controlled, double-blind trial
CONCLUSIONS: A single subanesthetic dose of esketamine can result in lower postoperative score on subthreshold depressive symptoms compared to the Group C on POD 1, without increasing the occurrence of postoperative adverse reactions.TRIAL REGISTRATION: Registration number: Chinese Clinical Trial Registry ChiCTR2200057028. Date of registration: 26/02/2022.PMID:38658886 | DOI:10.1186/s12888-024-05753-9 (Source: Cancer Control)
Source: Cancer Control - April 24, 2024 Category: Cancer & Oncology Authors: Huanwei Wang Rigen Te Jianxing Zhang Yanbing Su Hongxia Zhou Na Guo Dongmei Chi Wan Huang Source Type: research
Association of Water Arsenic With Incident Diabetes in U.S. Adults: The Multi-Ethnic Study of Atherosclerosis and the Strong Heart Study
CONCLUSIONS: Low to moderate water arsenic levels (<10 µg/L) were associated with T2D incidence in the SHFS and MESA cohorts.PMID:38656975 | DOI:10.2337/dc23-2231 (Source: Atherosclerosis)
Source: Atherosclerosis - April 24, 2024 Category: Cardiology Authors: Maya Spaur Marta Galvez-Fernandez Qixuan Chen Melissa A Lombard Benjamin C Bostick Pam Factor-Litvak Amanda M Fretts Steven J Shea Ana Navas-Acien Anne E Nigra Source Type: research
Thyroid Cancer and Endocrine Disruptive Chemicals: A Case-Control Study on Per-fluoroalkyl Substances (PFAS) and Other Persistent Organic Pollutants (POPs)
CONCLUSIONS: Our study suggests, for the first time in a case-control population, that exposure to some PFAS and PCBs associates with TC and some clinical and molecular features. On the contrary, an inverse correlation was found with both PFHxS and pollutants' mixture, likely due to a potential reverse causality.PMID:38657654 | DOI:10.1530/ETJ-23-0192 (Source: Cancer Control)
Source: Cancer Control - April 24, 2024 Category: Cancer & Oncology Authors: Valentina Cirello Marina Lugaresi Claudia Moneta Patrice Dufour Alessandro Manzo Erika Carbone Carla Colombo Laura Fugazzola Corinne Charlier Catherine Pirard Source Type: research
Expression of Heat Shock Protein 70 (HSP70) and Astacin Genes of < em > Strongyloides stercoralis < /em > as well as HSP70 and HSP17.1 Genes of < em > S. ratti < /em > in Adult and Larval Stages of < em > S. stercoralis < /em >
CONCLUSION: Higher expression levels of Sst-ast, Sst-hsp-70, and Sra-hsp-70 genes in the larval stages of S. stercoralis suggest the potential role of these enzymes in parasite cutaneous invasion and pathogenesis. However, higher expression of Srahsp-17.1 in adult forms is probably involved in resistance and survival mechanisms. The similarity in gene expression between S. stercoralis and S. ratti can provide helpful hints to better understand strongyloidiasis from various perspectives, including pathogenesis, proper diagnosis, and targeted treatment.PMID:38654956 | PMC:PMC11033530 | DOI:10.18502/ijpa.v19i1.15187 (Source: ...
Source: Iranian Journal of Parasitology - April 24, 2024 Category: Parasitology Authors: Maryam Alipour Leila Masoori Mohammad Davoodzadeh Gholami Majid Khoshmirsafa Elham Razmjou Nahid Jalallou Farzane Jafarian Reza Falak Ahmad Reza Meamar Source Type: research
Seroprevalence of Canine Toxocariasis in Three Rural Areas of Fars Province, Southern Iran
CONCLUSION: The high prevalence of Toxocara infection in dogs in the current study area confirms that infected dogs are an important source of Toxocara infection for their owners and people who are in close contact with these animals, especially children.PMID:38654942 | PMC:PMC11033540 | DOI:10.18502/ijpa.v19i1.15191 (Source: Iranian Journal of Parasitology)
Source: Iranian Journal of Parasitology - April 24, 2024 Category: Parasitology Authors: Ali Pouryousef Seyyed Mohammad Hashemi Mostafa Omidian Fattaneh Mikaeili Bahador Sarkari Source Type: research
Development of Low-Serum Culture Media for the in Vitro Cultivation of < em > Theileria annulata < /em > S15 Cell Line
CONCLUSION: The significant reduction in the required amount of serum and the remarkable cell growth achieved by using defined serum replacements for the production of cell culture media is a significant step towards the preparation of a proper cell culture medium for the production of bovine Theileriosis vaccine.PMID:38654949 | PMC:PMC11033534 | DOI:10.18502/ijpa.v19i1.15206 (Source: Iranian Journal of Parasitology)
Source: Iranian Journal of Parasitology - April 24, 2024 Category: Parasitology Authors: Gholamreza Habibi Asghar Afshari Amin Shahedi Mousa Hashemlou Ali Es-Haghi Mohamad Hosein Fallah Mehrabadi Saeid Fathi Source Type: research
Real-World Registry on the Pharmacotherapy of Multiple Myeloma and Associated Renal and Pulmonary Impairments in the Greater Gulf Region: Protocol for a Retrospective Real-World Data Study
CONCLUSIONS: Although MM is a predominant hematological disease, data on its prevalence and patients' characteristics in the Greater Gulf region are scarce. Therefore, this study will give us real-world insights into disease characteristics and various management approaches of patients with MM in the Greater Gulf region.INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): DERR1-10.2196/49861.PMID:38657230 | DOI:10.2196/49861 (Source: Cell Research)
Source: Cell Research - April 24, 2024 Category: Cytology Authors: Abdulnaser Nourallah Abdulrahman Alshehri Ayman Alhejazi Binyam Usman Ghada ElGohary Hafiz Malhan Ibraheem Motabi Khalil Al Farsi Mohammed Alshuaibi Mustaqeem Siddiqui Rasha Ghonema Ruba Yasin Taha Tarek Abouzeid Wesam Ahmed Mohanad Diab Ahmad Alhuraiji M Source Type: research
Psychiatrists can save lives with naloxone
CONCLUSIONS: Our findings highlight the importance of community access to naloxone in reducing opioid-related harm. Whilst removing the need for a prescription makes naloxone more accessible, it remains vital that doctors remain involved in this process to broaden the reach of supply to those at risk.PMID:38657130 | DOI:10.1177/10398562241249062 (Source: Australasian Psychiatry)
Source: Australasian Psychiatry - April 24, 2024 Category: Psychiatry Authors: Antigone Branchflower Robert M Lundin Craig Harvey Harry Hill Source Type: research
Effect of Psychosocial Interventions on Cancer's Caregiver Quality of Life: Meta-analysis
CONCLUSION: According to this meta-analysis, The psychological intervention program positively affected cancer caregiver's quality of life. Further randomised controlled trials are required to prove that psychological interventional programs are successful strategies for improving cancer caregiver's quality of life.PMID:38655551 | PMC:PMC11037513 | DOI:10.2174/17450179-v19-e230927-2022-HT14-4336-1 (Source: Clinical Practice and Epidemiology in Mental Health)
Source: Clinical Practice and Epidemiology in Mental Health - April 24, 2024 Category: Psychiatry Authors: C Vasantha Kalyani Kusum K Rohilla Pratima Gupta Amit Gupta Sweety Gupta Source Type: research
Coronavirus Anxiety, COVID Anxiety Syndrome and Mental Health: A Test Among Six Countries During March 2021
Clin Psychol Psychother. 2024 Mar-Apr;31(2):e2988. doi: 10.1002/cpp.2988.ABSTRACTThe negative impact of the COVID-19 pandemic on mental health outcomes is widely documented. Specifically, individuals experiencing greater degrees of severity in coronavirus anxiety have demonstrated higher levels of generalized anxiety, depression and psychological distress. Yet the pathways in which coronavirus anxiety confers vulnerability are not well known. The present investigation sought to address this gap in the scientific literature by testing the indirect effect of the COVID-19 anxiety syndrome, which centres on the function of det...
Source: Clinical Psychology and Psychotherapy - April 24, 2024 Category: Psychiatry Authors: Michael J Zvolensky Jafar Bakhshaie Brooke Y Redmond Tanya Smit Ana V Nik čević Marcantonio M Spada Walter Distaso Source Type: research
Magnitude of Thrombocytopenia and Associated Factors among Pregnant Women Attending the Antenatal Care Service Unit of Wachemo University Nigist Ellen Mohammed Comprehensive Specialized Hospital Hosanna, Southern Ethiopia
CONCLUSION: The magnitude of thrombocytopenia in this study was 14.8%. Rural residence, cigarette smoking, alcohol consumption, and anemia were significantly associated with thrombocytopenia. Therefore, the platelet count should be routinely determined during antenatal care visits for proper diagnosis and to minimize bleeding during and/or after childbirth.PMID:38655566 | PMC:PMC11039013 | DOI:10.1155/2024/8163447 (Source: Advances in Hematology)
Source: Advances in Hematology - April 24, 2024 Category: Hematology Authors: Dembelo Tirago Tilahun Yemane Edosa Tadasa Source Type: research
