Does the “ Non -IRA ” lesion status confuse you often ?..Try a blind primary PCI !
Primary PCI of IRA , continues to be a clinically & statisticaly validated  (Inspite of some ifs & buts) coronary reperfusion strategy. What to do, if  we happen to detect, a significant or borderline lesion in non- IRA territory ? There are too many guidelines scattered across cardiology literature either to “help or confuse” us. They argue for either immediate intervention , defer transiently, postpone or just ignore it , based on clinical ,hemodynamic*, Individual, institutional , or some other non academic factors. (Permanently deferred PCI is other wise called medical management is prac...
Source: Dr.S.Venkatesan MD - April 13, 2024 Category: Cardiology Authors: dr s venkatesan Tags: Uncategorized Source Type: blogs

From Wait Times to Real-Time: Assort Health Secures $3.5 Million to Scale First Generative AI for Healthcare Call Centers
Solution Erases Long Phone Holds for Patients, Supports Overwhelmed Medical Front Desk Workers, and Improves Patient Access to Physicians Assort Health is introducing the first generative AI solution built specifically for healthcare call centers, promising to erase that dreaded hold music forever. The company is announcing $3.5 million in funding, which will be used to continue scaling the team to meet rapidly accelerating demand with large healthcare organizations. Matt Humphrey, Partner at Quiet Capital led the funding round, joined by Four Acres, Tau Ventures, and a number of angel investors who are AI experts and heal...
Source: EMR and HIPAA - April 12, 2024 Category: Information Technology Authors: Healthcare IT News Tags: Health IT Company Healthcare IT Aditya Khosla Assort Health Athena Health Dr. David Garelick FLatiron Health Four Acres Health IT Funding Health IT Fundings Health IT Investment Illinois Bone and Joint Institute Chicago Division Je Source Type: blogs

Health Care ’s Debt Problem
By KIM BELLARD Among the many things that infuriate me about the U.S. healthcare system, health systems sending their patients to collections – or even suing them – is pretty high on the list (especially when they are “non-profit” and./or faith-based organizations, which we should expect to behave better). There’s no doubt medical debt in the U.S. is a huge problem. Studies have found that more than 100 million people have medical debt, many of whom don’t think they’ll ever be able to pay it off. Kaiser Family Foundation estimates Americans owe some $220b in medical debt, with 3 million people owing mor...
Source: The Health Care Blog - April 10, 2024 Category: Consumer Health News Authors: matthew holt Tags: Health Policy Bankruptcy Kim Bellard medical debt Medical Debt RIP Source Type: blogs

Fight Aging! Newsletter, April 8th 2024
In this study, we tested a stem cell secretome product, which contains extracellular vesicles and growth factors, cytoskeletal remodeling factors, and immunomodulatory factors. We examined the effects of 4 weeks of 2×/week unilateral intramuscular secretome injections (quadriceps) in ambulatory aged male C57BL/6 mice (22-24 months) compared to saline-injected aged-matched controls. Secretome delivery substantially increased whole-body lean mass and decreased fat mass, corresponding to higher myofiber cross-sectional area and smaller adipocyte size, respectively. Secretome-treated mice also had greater whole-bod...
Source: Fight Aging! - April 7, 2024 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Will Medical Facial Recognition Technology (mFRT) Reawaken Eugenics?
By MIKE MAGEE How comfortable is the FDA and Medical Ethics community with a new super-charged medical Facial Recognition Technology (mFRT) that claims it can “identify the early stages of autism in infants as young as 12 months?” That test already has a name -the RightEye GeoPref Autism Test. Its’ UC San Diego designer says it was 86% accurate in testing 400 infants and toddlers. Or how about Face2Gene which claims its’ mFRT tool already has linked half of the known human genetic syndromes to “facial patterns?” Or how about employers using mFRT facial and speech patterns to identify employees likely t...
Source: The Health Care Blog - April 4, 2024 Category: Consumer Health News Authors: matthew holt Tags: Uncategorized Source Type: blogs

Raised Inflammatory Markers Somewhat Correlate with Incidence of Age-Related Disease
Onset, progression, and resolution of inflammation are all driven by the interaction of many different complex signaling processes. The immune system as a whole is highly complex, an array of many different interacting populations of specialized cells. Nonetheless, there are a few individual circulating signal proteins that, to some degree at least, tend to reflect overall inflammatory status. Not reliably, but enough to produce correlations in patient populations of any reasonable size. Today's open access paper is a survey of the literature on inflammatory cytokines IL-6, TNF, and IL-1β, pulling reported measures...
Source: Fight Aging! - April 3, 2024 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Arguing the Primacy of Predation in Determining Species Longevity
Researchers here review a variety of species and conclude that defense against predation is the most important determinant of species longevity. Long-lived species tend to have shells, or fly, or live underground. Evolution will not favor longevity until other factors reduce extrinsic mortality at the hands of predators. After that, proximate biochemical causes of longevity can come into play in what looks to be a wide variety of ways. Various environmental morphological and behavioral factors can determine the longevity of representatives of various taxa. Long-lived species develop systems aimed at increasing org...
Source: Fight Aging! - April 3, 2024 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Median
Thoughts on crossing a statistical milestone. (Source: Depth-First)
Source: Depth-First - March 29, 2024 Category: Chemistry Authors: Richard L. Apodaca Source Type: blogs

Addressing physician workforce shortages [PODCAST]
Subscribe to The Podcast by KevinMD. Watch on YouTube. Catch up on old episodes! Join William E. Fox, chair-elect of the ACP Board of Regents, as we delve into the pressing issue of physician workforce shortages in primary care. William sheds light on recent alarming statistics, including the declining interest among medical students in pursuing Read more… Addressing physician workforce shortages [PODCAST] originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - March 26, 2024 Category: General Medicine Authors: Tags: Podcast Gastroenterology Source Type: blogs

Important Complications of Eisenmenger Syndrome
Transcript of the video: Eisenmenger syndrome is an important complication of large left to right shunts which develop later due to development of pulmonary vascular obstructive disease and severe pulmonary hypertension. The first report of Eisenmenger was by Victor Eisenmenger in 1897 and that was in a thirty year old person who later succumbed to massive hemoptysis. This highlights one of the most important complications of Eisenmenger syndrome, that is airway hemorrhage. Airway hemorrhage can occur in those who ascend to high altitude and during air travel. But it commonly occurs at low level itself. It is one of the mo...
Source: Cardiophile MD - March 26, 2024 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs

Fight Aging! Newsletter, March 25th 2024
This study also reports the expansion of satellite cells in human muscle with CR. This finding is critical to suggest translational relevance to the rodent data observed for more than a decade. Moreover, the increased expression of the plasminogen receptor Plg-RKT observed on human satellite cells during CR provided additional support for the theory that our rodent model is relevant to human biology. « Back to Top Interesting Insight into the Relationship Between TP53, Telomerase, and Telomere Length https://www.fightaging.org/archives/2024/03/interesting-insight-into-the-relationship-between-t...
Source: Fight Aging! - March 24, 2024 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Palpitations and presyncope in a 40-something
Discussion: Putting all of the information together this patient is most likely suffering from arrhythmogenic cardiomyopathy (AC) better known as ARVC. The medical hx is typical, with sudden onset tachydysrhythmia during physical exertion. It is not uncommon for the initial presentation to be sudden cardiac death (SCD). In fact it is one of the leading causes of SCD in people age less than 40 years. Thus it is very important to identify this disorder. AC is a disease in which myocardium is replaced by fibrofatty tissue. This usually and predominantly affects the RV free wall and apical regions, but it can affect the left v...
Source: Dr. Smith's ECG Blog - March 24, 2024 Category: Cardiology Authors: Magnus Nossen Source Type: blogs

Application and Funding Trends in Fiscal Year 2023
NIGMS continues to support a broad range of scientific topics and investigators within its research portfolio, including support for investigator-initiated research project grants (RPGs) at institutions throughout the country. As part of its commitment to transparency, NIGMS examines and publishes data on annual trends reflected in its RPG portfolio. In this post, we review and describe investigator-level trends associated with competing R01/R01-equivalent RPGs including those in the Institute’s R35 Maximizing Investigators’ Research Award (MIRA) program. NIGMS Investigator-Level Trends Research Grants In ord...
Source: NIGMS Feedback Loop Blog - National Institute of General Medical Sciences - March 20, 2024 Category: Biomedical Science Authors: Chrissa Chverchko Tags: Director’s Messages Funding Trends Funding Outcomes Funding Policies MIRA NIGMS Strategic Plan R01 Source Type: blogs

The Kids Are Definitely Not All Right: An Empirical Study Establishing a Statistically Significant Negative Relationship Between Receiving Accommodations in Law School and Passing the Bar Exam
Scott DeVito (Jacksonville University), The Kids Are Definitely Not All Right: An Empirical Study Establishing a Statistically Significant Negative Relationship Between Receiving Accommodations in Law School and Passing the Bar Exam, 102 Or. L. Rev. (2023): Many factors can influence... (Source: HealthLawProf Blog)
Source: HealthLawProf Blog - March 20, 2024 Category: Medical Law Authors: Katharine Van Tassel Source Type: blogs

Reporting on a Nine Month Self-Experiment in Taurine Supplementation
Today's post is a report from the community on the impact of taurine supplementation on a few biomarkers of interest. Taurine is a dietary amino acid, and circulating levels of taurine influence any number of biological processes. Taurine levels decrease with age in a variety of species; in humans circulating taurine is halved by age 50. You might recall that supplementation with taurine was demonstrated to modestly extend life in mice and improve health in old non-human primates. This may be largely due to enhanced performance of the antioxidant glutathione, and you might recall that other approaches to upregulation of gl...
Source: Fight Aging! - March 18, 2024 Category: Research Authors: Reason Tags: Self-Experimentation Source Type: blogs