Peer social network processes and adolescent health behaviors: A systematic review
Publication date: Available online 13 November 2019Source: Preventive MedicineAuthor(s): Shannon C. Montgomery, Michael Donnelly, Prachi Bhatnagar, Angela Carlin, Frank Kee, Ruth F. HunterAbstractResearch has highlighted the importance of peers for determining health behaviors in adolescents, yet these behaviors have typically been investigated in isolation. We need to understand common network processes operating across health behaviors collectively, in order to discern how social network processes impact health behaviors. Thus, this systematic review of studies investigated adolescent peer social networks and health beha...
Source: Preventive Medicine - November 13, 2019 Category: International Medicine & Public Health Source Type: research

The Relationships Between Perceived Discrimination and Utilization of Mental Health Services Among African Americans and Caribbean Blacks
This study contributes to the emerging body of evidence demonstrating that perce ived discrimination has a strong connection with the utilization of mental health services. (Source: Journal of Immigrant and Minority Health)
Source: Journal of Immigrant and Minority Health - November 13, 2019 Category: International Medicine & Public Health Source Type: research

Combine Factual Medical Knowledge and Distributed Word Representation to Improve Clinical Named Entity Recognition.
This study demonstrated an efficient way of integrating medical knowledge with distributed word representations for clinical NER. PMID: 30815153 [PubMed - indexed for MEDLINE] (Source: AMIA Annual Symposium Proceedings)
Source: AMIA Annual Symposium Proceedings - November 13, 2019 Category: Bioinformatics Tags: AMIA Annu Symp Proc Source Type: research

Neural responses to monetary incentives in bipolar disorder
Publication date: 2019Source: NeuroImage: Clinical, Volume 24Author(s): Sheri L. Johnson, Hershel Mehta, Terence A. Ketter, Ian H. Gotlib, Brian KnutsonAbstractAlthough behavioral sensitivity to reward predicts the onset and course of mania in bipolar disorder, the evidence for neural abnormalities in reward processing in bipolar disorder is mixed. To probe neural responsiveness to anticipated and received rewards in the context of bipolar disorder, we scanned individuals with remitted bipolar I disorder (n = 24) and well-matched controls (n = 24; matched for age and gender) using Functional Magnetic Resonance Imag...
Source: NeuroImage: Clinical - November 13, 2019 Category: Radiology Source Type: research

Growth Assessment of Pulmonary Adenocarcinomas Manifesting as Subsolid Nodules on CT: Comparison of Diameter-Based and Volume Measurements
ConclusionFor pulmonary adenocarcinomas presenting as subsolid nodules on CT, diameter-based assessment of nodule volume is reasonably accurate at confirming a lack of nodule growth but may overestimate actual growth, as compared to growth assessment based on measured volume. (Source: Academic Radiology)
Source: Academic Radiology - November 13, 2019 Category: Radiology Source Type: research

Efficacy and Safety of Brexpiprazole for the Treatment of Agitation in Alzheimer's Dementia: Two 12-Week, Randomized, Double-Blind, Placebo-Controlled Trials.
CONCLUSIONS: Brexpiprazole 2 mg/day has the potential to be efficacious, safe, and well tolerated in the treatment of AAD. PMID: 31708380 [PubMed - as supplied by publisher] (Source: The American Journal of Geriatric Psychiatry)
Source: The American Journal of Geriatric Psychiatry - November 13, 2019 Category: Psychiatry Tags: Am J Geriatr Psychiatry Source Type: research

Interobserver Agreement in Vascular Invasion Scoring and the Added Value of Immunohistochemistry for Vascular Markers to Predict Disease Relapse in Stage I Testicular Nonseminomas
Vascular invasion has been identified as an informative risk factor for relapse in stage I testicular nonseminomas, used to tailor treatment. We investigated interobserver agreement in vascular invasion reporting and studied the potential additional value of immunohistochemistry for vascular markers for predicting relapse. Patients (n=52) with stage I testicular nonseminomas undergoing surveillance (1993-2006) were included (median follow-up of 66 mo). Two formalin-fixed paraffin-embedded blocks with>1 cm2 tissue and tumor/normal parenchyma interface were stained with hematoxylin and eosin and CD31, FVIII,...
Source: The American Journal of Surgical Pathology - November 13, 2019 Category: Pathology Tags: Original Articles Source Type: research

Bracing in Adolescent Idiopathic Scoliosis Trial (BrAIST): Development and Validation of a Prognostic Model in Untreated Adolescent Idiopathic Scoliosis Using the Simplified Skeletal Maturity System
ConclusionsThis study provides the first rigorously validated model predicting a short-term outcome of untreated AIS. The resultant estimates can serve two important functions: 1) setting benchmarks for comparative effectiveness studies and 2) most importantly, providing clinicians and families with individual risk estimates to guide treatment decisions.Level of EvidenceLevel 1, prognostic. (Source: Spine Deformity)
Source: Spine Deformity - November 13, 2019 Category: Orthopaedics Source Type: research

Proximal Anchor Constructs and Its Influence on Surgical Outcome in Growth Rod Technique; A Comparison Between Rib Hooks and Pedicle Screws
ConclusionData from our study indicate that the proximal anchors, whether spine-based or rib-based, do not differ much in their outcome and complication rates, and the success of growing-rod technique depends largely on the security of cephalad and caudal foundations.Level of EvidenceLevel IV. (Source: Spine Deformity)
Source: Spine Deformity - November 13, 2019 Category: Orthopaedics Source Type: research

Pelvic Obliquity Correction in Distraction-Based Growth Friendly Implants
ConclusionIn distraction-based growth-friendly constructs, pelvic fixation with screws achieved better correction of pelvic obliquity than S hooks. Complications were almost twice as common with S hooks than screws, though this did not reach statistical significance. (Source: Spine Deformity)
Source: Spine Deformity - November 13, 2019 Category: Orthopaedics Source Type: research

Assessment of Construct Validity of the Oswestry Disability Index and the Scoliosis Research Society–30 Questionnaire (SRS-30) in Patients With Degenerative Spinal Disease
Publication date: November 2019Source: Spine Deformity, Volume 7, Issue 6Author(s): Jussi P. Repo, Ville T. Ponkilainen, Arja H. Häkkinen, Jari Ylinen, Paula Bergman, Kati KyröläAbstractStudy DesignObservational cohort study.ObjectivesTo measure and compare the structural validity of the Oswestry Disability Index (ODI) and the Scoliosis Research Society–30 (SRS-30) questionnaire in an adult population with prolonged degenerative thoracolumbar disease.Summary of Background DataThe ODI and the SRS-30 are commonly used patient-reported outcome instruments to assess back-specific disability and symptoms re...
Source: Spine Deformity - November 13, 2019 Category: Orthopaedics Source Type: research

Anterior capsule re-attachment in terrible triad elbow injury with coronoid tip fracture
ConclusionIn our experience, re-attaching the anterior capsule during the surgical treatment of TTEI with a coronoid tip fracture did not improve the clinical or radiographic outcomes after a mean follow-up of 54 months.Level of evidenceIV, retrospective study. (Source: Orthopaedics and Traumatology: Surgery and Research)
Source: Orthopaedics and Traumatology: Surgery and Research - November 13, 2019 Category: Orthopaedics Source Type: research

Comparison of Functional and Patient-Reported Outcomes between Direct Anterior and Lateral Surgical Approach One-year after Total Hip Arthroplasty in Canadian population: a cross-sectional study
ConclusionThe WOMAC, gait speed and SF-12 Physical component scores were significantly different in favour of the DA procedure at one-year after THA. However, only the WOMAC scores exceeded a clinically important threshold in favor of DA approach. The other self-report and physical performance measures were not significantly different between the two procedures at one-year postoperatively. (Source: Journal of Orthopaedics)
Source: Journal of Orthopaedics - November 13, 2019 Category: Orthopaedics Source Type: research

Local flaps vs. Free flaps for complex lower limb fractures: effect of flap choice on patient-reported outcomes
Publication date: Available online 12 November 2019Source: Journal of OrthopaedicsAuthor(s): Dilraj Singh Bhullar, Saravana Vail Karuppiah, Ahmed Aljawadi, Tess Gillham, Omar Fakih, Khadija Khamdan, Anand PillaiABSTRACTThe optimal flap cover for managing open lower limb fractures is debated. Most studies have reported on surgical outcome but clinical outcome is not well recognised. We aimed to determine whether there are differences in patient-reported quality of life (QoL) outcome between local flap versus free flap.All patients admitted with lower limb open fractures were retrospectively reviewed. Patient notes were asse...
Source: Journal of Orthopaedics - November 13, 2019 Category: Orthopaedics Source Type: research

Efficacy of the Use of Fractional CO2RE Intima Laser Treatment in Stress and Mixed Urinary Incontinence
The objective of this clinical study was to evaluate the efficacy of a vaginal CO2 laser treatment (CO2RE Intima) in patients with moderate, severe and very severe stress urinary incontinence (SUI) or mixed urinary incontinence (MUI), as well as its impact in sexual relations.DesignThis was a single-center, prospective, interventional study that included 25 women aged 35-68 years who presented with moderate, severe and very severe symptoms of SUI or MUI, based on Sandvik index and ICIQ-UI scores. A series of three fractional micro-ablative CO2 vaginal laser treatment sessions was performed, each spaced 4 to 6 weeks apart. ...
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - November 13, 2019 Category: OBGYN Source Type: research

Bihemispheric changes associated with cognition in patients with chronic brainstem stroke
Objective: We aimed to identify brain changes associated with preserved cognitive function in patients with chronic brainstem stroke. Methods: Twelve patients with chronic brainstem stroke and 24 age-matched healthy controls were included in this retrospective study. All participants underwent T1-weighted, diffusion tensor, and resting-state functional MRI. Gray matter density, fractional anisotropy, and mean diffusivity maps from diffusion tensor imaging and seven cognition-related independent component maps from resting-state functional MRI were used to identify differences in brain volume, structural connectivity, ...
Source: NeuroReport - November 13, 2019 Category: Neurology Tags: Clinical Neuroscience Source Type: research

An Observational Descriptive Cross Sectional Multicenter Study of Health Related Quality of Life Among Iraqi Patients After Total Hip Replacement
ConclusionsTHR improved HRQOL. BMI was the only significant independent factor that was negatively correlated with HRQOL. (Source: Annals of Medicine and Surgery)
Source: Annals of Medicine and Surgery - November 13, 2019 Category: General Medicine Source Type: research

First aid management of paediatric burn and scald injuries in Southern Malawi: A mixed methods study
ConclusionsThis study provides the largest description of first aid use in sub-Saharan Africa, strengthening the evidence that remedies aside from water are commonly used and that higher parental education levels do not translate to increased use of water, but rather use of alternative treatments. Our qualitative findings allow improved understanding of how first aid for paediatric burns is perceived in rural Malawi communities, providing insight as to why certain first aid choices are made and the possible barriers and facilitators to the adoption of water as a first aid treatment. (Source: Burns)
Source: Burns - November 13, 2019 Category: Dermatology Source Type: research

Characteristics and outcomes of patients with grill-related Burn injuries admitted to the Cologne Burn Center, Germany
ConclusionGrill-related injuries are a relatively common cause of admission to the Cologne Burn Center. Although grill-related injuries underwent a less aggressive approach than the other investigated fire injuries, the former represent a public health concern because they mainly affect the upper body, with both psychologic and aesthetic consequences. We recommend a German nationwide multi-centric study of the patterns and characteristics of burn injury. (Source: Burns)
Source: Burns - November 13, 2019 Category: Dermatology Source Type: research

Quantitative and qualitative assessments of intraosseous neurovascular canals in dentate and posteriorly edentulous individuals in lateral maxillary sinus wall
Conclusion: This study reveals that dentate maxillary jaws present larger diameters as compared to posteriorly edentulous jaws, although the IA course remains the same. As these canal structures contain neurovascular bundles with diameters that may be large enough to cause clinically substantial complications, a thorough pre-surgical planning is therefore highly advisable. (Source: The Saudi Dental Journal)
Source: The Saudi Dental Journal - November 13, 2019 Category: Dentistry Source Type: research

Hydrocortisone Compared with Placebo in Patients with Septic Shock Satisfying the Sepsis-3 Diagnostic Criteria and APROCCHSS Study Inclusion Criteria A Post Hoc Analysis of the ADRENAL Trial
Conclusions In apost hoc analysis of the ADRENAL trial participants who fulfilled either the Sepsis-3 or the APROCCHSS inclusion criteria, a continuous infusion of hydrocortisone did not result in a lower 90-day mortality than placebo in septic shock. (Source: Anesthesiology)
Source: Anesthesiology - November 13, 2019 Category: Anesthesiology Source Type: research

Peripheral Nerve Blocks for Ambulatory Shoulder Surgery A Population-based Cohort Study of Outcomes and Resource Utilization
Conclusions In ambulatory shoulder surgery, nerve blocks were not associated with a significant difference in adverse postoperative outcomes. Costs were statistically higher with a block, but this increase is not likely clinically relevant. (Source: Anesthesiology)
Source: Anesthesiology - November 13, 2019 Category: Anesthesiology Source Type: research

Poor Sleep Quality's Association With Soccer Injuries: Preliminary Data.
CONCLUSIONS: Soccer players who exhibit lower sleep quality or nonrestorative sleep show associations with increased number and severity of musculoskeletal injuries. PMID: 31711034 [PubMed - as supplied by publisher] (Source: International Journal of Sports Physiology and Performance)
Source: International Journal of Sports Physiology and Performance - November 13, 2019 Category: Sports Medicine Tags: Int J Sports Physiol Perform Source Type: research

Trends in Total Hip Arthroplasty in Germany from 2007 to 2016: What Has Changed and Where Are We Now?
CONCLUSION: The present data clearly demonstrate an increase in the use of cementless fixation for THA in Germany during the last decade and document a rise in ssTHA in recent years with, in contrast, the use of HR decreasing to a minimum. PMID: 31711254 [PubMed - as supplied by publisher] (Source: Zeitschrift fur Orthopadie und Unfallchirurgie)
Source: Zeitschrift fur Orthopadie und Unfallchirurgie - November 13, 2019 Category: Orthopaedics Tags: Z Orthop Unfall Source Type: research

Amphotericin b-loaded eudragit rl100 nanoparticles coated with hyaluronic acid for the treatment of vulvovaginal candidiasis
In this study, amphotericin B-loaded Eudragit RL100 nanoparticles coated with hyaluronic acid (AMP EUD nanoparticles/HA) were developed to overcome the drawbacks of the conventional formulations. AMP EUD nanoparticles/HA were synthesized by nanoprecipitation, formulated by statistical experimental design, and characterized. AMP release from EUD nanoparticles/HA and its antifungal activity in a murine model of VVC were evaluated. Nanoparticles showed 147.6 ± 16.7 nm of diameter, 0.301 ± 0.09 of polydispersity index, - 29.9 ± 3.76 mV of zeta potenti...
Source: Carbohydrate Polymers - November 13, 2019 Category: Biomedical Science Source Type: research

Electrochemical noise analysis to identify the corrosion type using the stockwell transform and the shannon energy: Part II
Publication date: Available online 12 November 2019Source: Journal of Electroanalytical ChemistryAuthor(s): O.J. Ramos-Negrón, R.F. Escobar-Jiménez, J.H. Arellano-Pérez, J. Uruchurtu-Chavarín, J.F. Gómez-Aguilar, M.A. Lucio-GarcíaAbstractIn a previous manuscript, the Stockwell transform (ST) and Shannon energy (SSE) methods were presented as a new proposal to identify the corrosion type at room temperature. The present manuscript aim is demonstrating the effectiveness of the ST and SSE methods for evaluating the corrosion type and rate through Electrochemical Noise technique at dif...
Source: Journal of Electroanalytical Chemistry - November 13, 2019 Category: Chemistry Source Type: research

Lung Ultrasound–Guided Dry Weight Assessment and Echocardiographic Measures in Hypertensive Hemodialysis Patients: A Randomized Controlled Study
We report on the prespecified secondary outcome, echocardiographic indexes of LV function, from a previously reported study of the effect of lung ultrasound (US)-guided dry weight reduction on systolic blood pressure.Study DesignSingle-blind randomized trial.Settings & Participants71 clinically euvolemic hypertensive hemodialysis patients in Greece and Slovenia.InterventionThe active intervention group’s (n = 35) volume removal was guided by the total number of lung US B-lines observed every week before a midweek dialysis session. The usual-care group (n = 36) was treated using standard-of-car...
Source: American Journal of Kidney Diseases - November 13, 2019 Category: Urology & Nephrology Source Type: research

Financial hardship among rural cancer survivors: An analysis of the Medical Expenditure Panel Survey
This study examined contrasts in financial hardship among 1419 rural and urban cancer survivors using the 2011 Medical Expenditure Panel Survey supplement – The Effects of Cancer and Its Treatment on Finances. We combined four questions, creating a measure of material financial hardship, and examined one question on financial worry. We conducted multivariable logistic regression analyses, which produced odds ratios (OR) for factors associated with financial hardship and worry, and then generated average adjusted predicted probabilities. We focused on rural and urban differences classified by metropolitan statistical ...
Source: Preventive Medicine - November 13, 2019 Category: International Medicine & Public Health Source Type: research

Unilateral jump landing neuromechanics of individuals with chronic ankle instability
ConclusionsIndividuals with CAI present neuromechanical differences during unilateral jump landing compared to healthy individuals. The results of this study will improve our understanding of underlying deficits associated with CAI and will help researchers and clinicians to better target them during rehabilitation. (Source: Journal of Science and Medicine in Sport)
Source: Journal of Science and Medicine in Sport - November 13, 2019 Category: Sports Medicine Source Type: research

Association study between CYP24A1 gene polymorphisms and cancer risk
Publication date: Available online 11 November 2019Source: Pathology - Research and PracticeAuthor(s): Can Yi, Chao Huang, Huan Wang, Chen Wang, Lijuan Dong, Xiuli Gu, Xianhong Feng, Bifeng ChenAbstractCYP24A1, an essential gene in regulation of vitamin D, has been reported to play an important role in enhancing immune activity and inhibiting tumorigenesis. Previous studies proposed that rs2585428, rs4809960, rs6022999 and rs6068816 in CYP24A1 gene might be greatly associated with cancer risk. To validate the findings, we here investigated the associations of these four polymorphisms and colorectal cancer (CRC) risk in a c...
Source: Pathology Research and Practice - November 13, 2019 Category: Pathology Source Type: research

Challenges in Successful Management of Haemophiliac knee Arthropathy: Our Experience in a Tertiary Centre
ConclusionsTotal knee arthroplasty has good outcome with respect to clinical as well as functional outcome in haemophilic arthropathy. Although the results and outcome of total knee arthroplasty in haemophilic knee arthropathy may still be inferior to the results seen in a normal individual, a multidisciplinary approach yields a better functional and quality of living in such haemophilic patients. (Source: Journal of Orthopaedics)
Source: Journal of Orthopaedics - November 13, 2019 Category: Orthopaedics Source Type: research

Avoid post operative bracing to reduce ACL rerupture rates
ConclusionACL rehabilitation without a knee brace can indirectly prevent rerupture and is a cheaper as well as a safer method with better outcomes. (Source: European Journal of Orthopaedic Surgery and Traumatology)
Source: European Journal of Orthopaedic Surgery and Traumatology - November 13, 2019 Category: Orthopaedics Source Type: research

Bone Formation of Titanium Implant Surfaces Treated with Submicron Poly(lactide-co-glycolide)/Recombinant Human Transforming Growth Factor- β2 Particles by the Electrospray Method: An In Vivo Study.
This study evaluated the effect of anodized titanium implants coated with submicron-sized poly(lactide-co-glycolide) (PLGA)/recombinant human transforming growth factor- β2 (rhTGF- β2) particles via electrospray on osseointegration in an in vivo model. MATERIALS AND METHODS: An experimental group of anodized titanium implants coated with submicron PLGA/rhTGF-β2 particles by electrospray was compared topographically and histomorphometrically to noncoated anodized implants. Forty-eight anodized titanium implants were inserted into the tibias of 12 New Zealand rabbits. The histomorphometric specimens were p...
Source: International Journal of Oral and Maxillofacial Implants - November 13, 2019 Category: ENT & OMF Tags: Int J Oral Maxillofac Implants Source Type: research

Effect of Peri-implant Keratinized Tissue Width on Tissue Health and Stability: Systematic Review and Meta-analysis.
Authors: Longoni S, Tinto M, Pacifico C, Sartori M, Andreano A Abstract PURPOSE: There is uncertainty in the literature on whether the presence of keratinized tissue (KT) ameliorates the state of peri-implant tissue health. A systematic review and meta-analysis was performed to synthesize evidence on the association between peri-implant keratinization, defined as adequate (≥ 2 mm) or inadequate (0 to 2 mm), and peri-implant health and stability, measured as tissue inflammation, plaque accumulation, tendency to bleeding, and probing depth (PD). MATERIALS AND METHODS: This systematic review adhered to the Pref...
Source: International Journal of Oral and Maxillofacial Implants - November 13, 2019 Category: ENT & OMF Tags: Int J Oral Maxillofac Implants Source Type: research

Impact of Implant Length on Survival of Rough-Surface Implants in Nonaugmented Posterior Areas: A Systematic Review and Meta-Regression Analysis.
Authors: Ravidà A, Majzoub J, Alassadi M, Saleh MH, Askar H, Wang HL Abstract PURPOSE: Short implants have been considered as an alternative to regular implants even where native bone is potentially adequate. Hence, the aim of this study was to evaluate the impact of implant length on its survival. MATERIALS AND METHODS: A systematic literature search of randomized controlled trials and prospective studies was performed using the PubMed (MEDLINE), EMBASE, and Cochrane databases. Meta-regression analysis determined the effect of the length on the implant survival rate. RESULTS: Sixty-six studies compr...
Source: International Journal of Oral and Maxillofacial Implants - November 13, 2019 Category: ENT & OMF Tags: Int J Oral Maxillofac Implants Source Type: research

Impact of Implant and Site Characteristics on the Pattern of Bone Loss in Peri-implantitis.
Authors: Shatta A, Bissada NF, Ricchetti P, Paes A, Demko C Abstract PURPOSE: To assess the pattern of bone loss in peri-implantitis in partially edentulous patients and relate patient and implant/site characteristics that may influence such patterns. MATERIALS AND METHODS: In this retrospective study, the records of partially edentulous patients with dental implants were stratified according to sex, age, smoking, and diabetes. Implants were stratified according to site, number of years in function, presence of adjacent implants, diameter, bone-grafted site, and implant platform. All these variables were obtain...
Source: International Journal of Oral and Maxillofacial Implants - November 13, 2019 Category: ENT & OMF Tags: Int J Oral Maxillofac Implants Source Type: research

Biologic and Technical Complications of Implant-Supported Immediately Loaded Fixed Full-Arch Prostheses: An Evaluation of Up to 6 Years.
This study investigated patients who received treatment with immediately loaded fixed full-arch prostheses using four to six implants from 2007 to 2013. The investigation included biologic and technical complications. Complications were depicted regarding their prevalence and their first time of occurrence. Statistical analysis was performed regarding the differences of the mean complication values between the mandible and the maxilla and between technical and biologic complications. RESULTS: The investigation included 482 immediately loaded fixed full-arch prostheses (380 patients, mean observation period: 23.5 months...
Source: International Journal of Oral and Maxillofacial Implants - November 13, 2019 Category: ENT & OMF Tags: Int J Oral Maxillofac Implants Source Type: research

Cannabis Use for Symptom Relief in Multiple Sclerosis: A Cross-Sectional Survey of Webinar Attendees in the US and Canada
Publication date: Available online 11 November 2019Source: Multiple Sclerosis and Related DisordersAuthor(s): Andrea Hildebrand, Jessica Minnier, Michelle H. CameronAbstractBackgroundWith the expansion of medical and recreational legalization of cannabis, there is growing interest in cannabis use by people with multiple sclerosis (MS). Research supports that cannabis relieves MS-related pain and spasticity, two common symptoms of MS. However, there is limited information available about cannabis use in people with MS across the United States and Canada.Methods1,015 people with MS in the US and Canada participated in an inf...
Source: Multiple Sclerosis and Related Disorders - November 13, 2019 Category: Neurology Source Type: research

Efficacy and adverse event profile of cannabidiol and medicinal cannabis for treatment-resistant epilepsy: Systematic review and meta-analysis
Publication date: January 2020Source: Epilepsy & Behavior, Volume 102Author(s): Renandro de Carvalho Reis, Kelson James Almeida, Luciano da Silva Lopes, Cíntia Maria de Melo Mendes, Edson Bor-Seng-ShuAbstractThis paper aimed to systematically examine the efficacy and adverse event (AE) profile of cannabidiol and medicinal cannabis by analyzing qualitative and meta-analytic data. We used the terms (“Cannabidiol” OR “Cannabis”) AND “Epilepsy” AND (“Treatment” OR “Therapeutics”) as keywords to retrieve studies indexed on PubMed, ScienceDirect, and CENTRAL ...
Source: Epilepsy and Behavior - November 13, 2019 Category: Neurology Source Type: research

A transcranial sonography study of brainstem and its association with depression in idiopathic generalized epilepsy with tonic–clonic seizures
In conclusion, BR echogenic signal alterations in TCS can be a biomarker for depression in epilepsy, but it might not be associated with epilepsy itself. The alterations of SN echogenic area and TV width in TCS may reflect a potential role of SN and diencephalon structure in the pathogenesis of epilepsy, which needs to be further elucidated. (Source: Epilepsy and Behavior)
Source: Epilepsy and Behavior - November 13, 2019 Category: Neurology Source Type: research

Association between interleukin-8 rs4073 polymorphism and prostate cancer: A meta-analysis
ConclusionThe major findings of this meta-analysis suggested that IL-8 rs4073 polymorphism is significantly associated with risk of prostate cancer. (Source: Journal of the Formosan Medical Association)
Source: Journal of the Formosan Medical Association - November 13, 2019 Category: General Medicine Source Type: research

Fecal calprotectin as a factor that supports the pathogenicity of Dientamoeba fragilis
In conclusion, increased levels of f-CP are shown as a marker of an inflammatory disease of the lower gastrointestinal tract in infected humans. There is continues controversy about the pathogenicity of D. fragilis in symptomatic and asymptomatic patients. The findings of this study contribute to the ongoing debate about the pathogenicity of D. fragilis. In our study, the potential pathogenicity of D. fragilis is associated with increased f-CP concentrations with parasite detection in the fecal samples and therefore we assume that the parasite is not only a harmless commensal. In summary, higher levels of f-CP found in D. ...
Source: Microbial Pathogenesis - November 13, 2019 Category: Infectious Diseases Source Type: research

Left Ventricular Function, Epicardial Adipose Tissue, and Carotid Intima-Media Thickness in Children and Adolescents With Vertical HIV Infection
Background: Life expectancy of HIV patients has increased considerably as a result of antiretroviral therapy (ART), and cardiovascular (CV) disease has emerged as an important late concern. People with HIV infection could have an impaired systolic function; however data on diastolic function and markers of CV risk, such as epicardial adipose tissue (EAT) and intima-media thickness (IMT), are lacking. Aim of this study is to evaluate left ventricular function, EAT, and IMT in children and adolescents with vertically acquired HIV infection. Methods: We enrolled 29 subjects on ART (13, 45% men; median age of 13.0, and in...
Source: JAIDS Journal of Acquired Immune Deficiency Syndromes - November 13, 2019 Category: Infectious Diseases Tags: Clinical Science Source Type: research

Estimated versus actual; The accuracy of accounting for blood loss during endoscopic sinus surgery
ConclusionThe surgeons studied had EBL that were statistically significantly less than ABL both at hourly intervals during the surgery and at the conclusion of the case. As a result there exists potential for adverse consequences in clinical care and in efforts in medical research/advancement. (Source: American Journal of Otolaryngology)
Source: American Journal of Otolaryngology - November 13, 2019 Category: Endocrinology Source Type: research

[Effectiveness of interventions to strengthen cognitive resources in nursing home residents : A  systematic review and network meta-analysis].
[Effectiveness of interventions to strengthen cognitive resources in nursing home residents : A systematic review and network meta-analysis]. Z Gerontol Geriatr. 2019 Nov 13;: Authors: Wöhl C, Siebert H, Blättner B Abstract BACKGROUND: Strengthening cognitive resources of residents in nursing homes is an important goal of preventive activities. The aim of this systematic review was to answer the question which intervention is most effective for nursing home residents to strengthen their cognitive resources. METHOD: A systematic literature search was carried out in the Cochrane...
Source: Zeitschrift fur Gerontologie und Geriatrie - November 13, 2019 Category: Geriatrics Authors: Wöhl C, Siebert H, Blättner B Tags: Z Gerontol Geriatr Source Type: research

Development of an electronic trigger tool at a children's hospital within an academic medical center.
CONCLUSION: This study lays the foundation for further studies to develop a robust pediatric trigger tool that may involve developing multi-element triggers, determining sensitivity and specificity of triggers, or mobilizing the trigger tool to an automated system. Trigger tools can be individualized to meet each institutions' needs and unique patient population. PMID: 31724037 [PubMed - in process] (Source: American Journal of Health-System Pharmacy : AJHP)
Source: American Journal of Health-System Pharmacy : AJHP - November 13, 2019 Category: Drugs & Pharmacology Authors: Fortenberry M, Odinet J, Shah P, McKinzie C, Murphy K, Faircloth CB, Falato C, Pappas A Tags: Am J Health Syst Pharm Source Type: research

Impact of discharge medication bedside delivery service on hospital reutilization.
CONCLUSION: There was no difference in 30-day hospital reutilization related to the index visit with the implementation of meds-to-beds service in the absence of other transitions-of-care interventions. PMID: 31724038 [PubMed - in process] (Source: American Journal of Health-System Pharmacy : AJHP)
Source: American Journal of Health-System Pharmacy : AJHP - November 13, 2019 Category: Drugs & Pharmacology Authors: Patel A, Dodd MA, D'Angio R, Hellinga R, Ahmed A, Vanderwoude M, Sarangarm P Tags: Am J Health Syst Pharm Source Type: research

Human Herpesvirus 6 as an Indicator of Cytomegalovirus Infection and Its Attributable Disease Symptoms in Liver Transplant Recipients.
CONCLUSIONS: We found that human herpesvirus 6 infection is often associated with cytomegalovirus reactivation and cytomegalovirus-attributable disease symptoms. PMID: 31724929 [PubMed - as supplied by publisher] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - November 13, 2019 Category: Transplant Surgery Authors: Jamalidoust M, Aliabadi N, Namayandeh M, Ziyaeyan M Tags: Exp Clin Transplant Source Type: research

Effects of Ovarian Transplant on Anti-M üllerian Hormone, Kisspeptin-1, and Kisspeptin-1 Receptor Levels in Rats.
CONCLUSIONS: Our findings suggest that, in rats, results were better in the peritoneum transplant group than in the subcutaneous transplant group. We also found that serum anti-Müllerian hormone levels were lower in the transplant groups than in the estrous group, although levels were not completely decreased to zero. These results support the finding that ovarian activities continue after transplant. PMID: 31724927 [PubMed - as supplied by publisher] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - November 13, 2019 Category: Transplant Surgery Authors: Risvanli A, Ocal H, Timurkaan N, Ipek P, Cevik A, Seker I Tags: Exp Clin Transplant Source Type: research

[Influence of methodological changes on unicausal cause-of-death statistics and potentials of a  multicausal data basis].
CONCLUSIONS: Temporal and regional comparisons must always be interpreted against the background of changing methodological guidelines and procedures. Multicausal analyses in this respect offer the chance for the future to mitigate the difficulties of a unicausal approach. PMID: 31720737 [PubMed - as supplied by publisher] (Source: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz)
Source: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz - November 13, 2019 Category: International Medicine & Public Health Authors: Buschner A, Grunwald-Mühlberger A Tags: Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz Source Type: research