Which is Better in Predicting CT Scores in Patients with Chronic Rhinosinusitis after Medical treatment-Baseline Rhinosinusitis Disability Index (RSDI) or Endoscopic Score?
ConclusionStatistically significant (p < 0.001) association was found between baseline Lund-Kennedy endoscopic scores and Mackay-Lund CT scores post medical treatment. No significant association was found between RSDI scores and Mackay-Lund CT scores. ROC analysis indicated that Lund- Kennedy endoscopy score is a more accurate tool than RSDI score to predict a Mackay-Lund CT scores after medical treatment. (Source: Indian Journal of Otolaryngology and Head and Neck Surgery)
Source: Indian Journal of Otolaryngology and Head and Neck Surgery - April 23, 2024 Category: ENT & OMF Source Type: research
Demand forecasting for platelet usage: From univariate time series to multivariable models
This study is the first to utilize different methods from statistical time series models to data-driven regression and machine learning techniques for platelet transfusion using clinical predictors and with different amounts of data. We find that the multivariable approaches have the highest accuracy in general, however, if sufficient data are available, a simpler time series approach appears to be sufficient. We also comment on the approach to choose predictors for the multivariable models. (Source: PLoS One)
Source: PLoS One - April 23, 2024 Category: Biomedical Science Authors: Maryam Motamedi Source Type: research
Prevalence and implications of bilateral and solely contralateral lymph node metastases in oral squamous cell carcinoma
ConclusionsB/SC LNMs are rare in patients with OSCC, especially in those who present with clinico-radiologically negative ipsilateral necks. Higher rates of B/SC metastases occur in case of advanced tumors and those localized at the upper jaw or floor of the mouth. Ipsilateral LNMs significantly elevate the risk of contralateral LNMs, tripling the associated risk.Clinical relevanceThese findings provide valuable insights for surgeons considering contralateral ND or extended adjuvant treatment for OSCC patients. However, the absence of high-level evidence from randomized controlled trials impedes the establishment of a defi...
Source: Clinical Oral Investigations - April 23, 2024 Category: Dentistry Source Type: research
Rebleeding following aneurysmal subarachnoid hemorrhage before 'endovascular first treatment: a retrospective case-control study of published scoring systems
Conclusions
For aSAH patients treated in an ultra-early timeframe matched on size and parent vessel location, WFNS grade was superior to three published models for re-bleed prediction. Future re-bleed prediction models should incorporate the WFNS grade. (Source: Journal of NeuroInterventional Surgery)
Source: Journal of NeuroInterventional Surgery - April 23, 2024 Category: Neurosurgery Authors: Dissanayake, A. S., Burrows, E., Ho, K. M., Phillips, T. J., Honeybul, S., Hankey, G. J. Tags: Hemorrhagic stroke Source Type: research
How well global dietary intake estimates agree: a case of sodium consumption
AbstractGlobal dietary data repositories are key components of nutrition surveillance. The two most comprehensive databases, the Global Dietary Database (GDD) and the Global Burden Disease (GBD), provide national dietary intake estimates but use different data sources and models to generate estimates. To explore the agreement between GDD and GBD estimates, we compared country-specific average daily sodium intakes in 169 countries over a 28-year period using descriptive statistics, the Bland –Altman method, and prevalence exceeding the intake reference level of 2.3 g/day. We detected a staggering 36% difference between G...
Source: Journal of Public Health Policy - April 23, 2024 Category: Health Management Source Type: research
Statewide Survey of Primary Care and Subspecialty Providers on Hepatocellular Carcinoma Risk-Stratification and Surveillance Practices
ConclusionsIn this statewide survey, there were great knowledge gaps in HCC surveillance among PCPs and most respondents expressed interest in strategies to increase appropriate HCC surveillance. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - April 23, 2024 Category: Gastroenterology Source Type: research
Efficacy of comprehensive structured exercise program on claudication pain and quality of life in type 2 diabetes mellitus with peripheral arterial disease
ConclusionIn the present study we found that comprehensive structured exercise program improves the arterial indices, quality of life, walking ability and reduces claudication pain in type 2 diabetes mellitus with peripheral arterial disease. (Source: Journal of Diabetes and Metabolic Disorders)
Source: Journal of Diabetes and Metabolic Disorders - April 23, 2024 Category: Endocrinology Source Type: research
The use of FreeStyle libre improves glycaemic control along with reducing diabetes burden and hospital admissions in a socially deprived Northwest English population
ConclusionThe use of FSL resulted in statistically significant reductions in hospital admissions, HbA1c and reported hypoglycaemic episodes among diabetics in a socially deprived Northwest region of England. These outcomes show a direct association with a higher questionnaire score. (Source: Journal of Diabetes and Metabolic Disorders)
Source: Journal of Diabetes and Metabolic Disorders - April 23, 2024 Category: Endocrinology Source Type: research
Metabolomic Analysis of Human Cirrhosis and Hepatocellular Carcinoma: A Pilot Study
ConclusionOur findings give promising insides into the metabolic changes during HCC carcinogenesis and provide candidate biomarkers for future studies. Campesterol and furoylglycine in particular were identified as possible biomarkers for HCC progression. Moreover, eight metabolites were detected as predictors for poor overall survival.Graphical Abstract (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - April 23, 2024 Category: Gastroenterology Source Type: research
Anterior versus posterior component separation technique for advanced abdominal wall reconstruction: a proposed algorithm
ConclusionFollowing a proposed algorithm, the anterior fascial closure rate was high and similar for both techniques. As postoperative wound morbidity is significantly increased after ACST, our findings support recommending TAR for defects up to 14 cm in width, while favoring open ACST for larger defects. (Source: Hernia)
Source: Hernia - April 23, 2024 Category: Sports Medicine Source Type: research
The characteristics of white dot syndromes following COVID-19 Vaccines: a systematic review
ConclusionWhite dot syndromes are very rare entities. Our findings highlight a possible association between COVID-19 vaccines and the occurrence of white dot syndromes. However, larger studies with good quality should be implemented to confirm these findings. (Source: International Ophthalmology)
Source: International Ophthalmology - April 23, 2024 Category: Opthalmology Source Type: research
Inconsistencies in rater-based assessments mainly affect borderline candidates: but using simple heuristics might improve pass-fail decisions
DiscussionInconsistencies in performance judgments continue to be a matter of concern, and we provide empirical evidence for them to be related to candidate performance. We discuss implications for research and the advantages of adopting the perspective of ecological rationality. We point to directions both for further research and for development of assessment practices. (Source: Advances in Health Sciences Education)
Source: Advances in Health Sciences Education - April 23, 2024 Category: Universities & Medical Training Source Type: research
Cancers, Vol. 16, Pages 1617: Interaction of Colorectal Neoplasm Risk Factors and Association with Metabolic Health Status Focusing on Normal Waist-to-Hip Ratio in Adults
Conclusions: An increase in FRS and HbA1c or a positive H. pylori infection still warrants vigilance for colorectal adenoma risk when WHR is 0.9. These factors interacted with each other and were found to have a minimal decline in adenoma risk when considering the interaction between WHR and FRS. (Source: Cancers)
Source: Cancers - April 23, 2024 Category: Cancer & Oncology Authors: Ying-Chun Lin Hung-Ju Ko Lo-Yip Yu Ming-Jen Chen Horng-Yuan Wang Shou-Chuan Shih Chuan-Chuan Liu Yang-Che Kuo Kuang-Chun Hu Tags: Article Source Type: research
Viruses, Vol. 16, Pages 657: Wide Real-Life Data Support Reduced Sensitivity of Antigen Tests for Omicron SARS-CoV-2 Infections
Alejandro Giorgetti
Antonio Conti
Maria Rosaria Capobianchi
Federico Giovanni Gobbi
Concetta Castilletti
With the continuous spread of new SARS-CoV-2 variants of concern (VOCs), the monitoring of diagnostic test performances is mandatory. We evaluated the changes in antigen diagnostic tests&rsquo; (ADTs) accuracy along the Delta to Omicron VOCs transition, exploring the N protein mutations possibly affecting ADT sensitivity and assessing the best sampling site for the diagnosis of Omicron infections. In total, 5175 subjects were enrolled from 1 October 2021 to 15 July 2022. The inclusion criteria were...
Source: Viruses - April 23, 2024 Category: Virology Authors: Chiara Piubelli Davide Treggiari Denise Lavezzari Michela Deiana Klevia Dishnica Emma Maria Sole Tosato Cristina Mazzi Paolo Cattaneo Antonio Mori Elena Pomari Lavinia Nicolini Martina Leonardi Francesca Perandin Fabio Formenti Alejandro Giorgetti Antonio Tags: Article Source Type: research
Viruses, Vol. 16, Pages 655: Impact of the COVID-19 Pandemic on Hepatitis C Treatment Initiation in British Columbia, Canada: An Interrupted Time Series Study
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Naveed Zafar Janjua
We investigated the impacts of the COVID-19 pandemic on hepatitis C (HCV) treatment initiation, including by birth cohort and injection drug use status, in British Columbia (BC), Canada. Using population data from the BC COVID-19 Cohort, we conducted interrupted time series analyses, estimating changes in HCV treatment initiation following the introduction of pandemic-related policies in March 2020. The study included a pre-policy period (April 2018 to March 2020) and three follow-up periods (April to December 2020, January to December 2021, and January to December 2022). The level of HCV treatm...
Source: Viruses - April 23, 2024 Category: Virology Authors: Richard L. Morrow Mawuena Binka Julia Li Mike Irvine Sofia R. Bartlett Stanley Wong Dahn Jeong Jean Damascene Makuza Jason Wong Amanda Yu Mel Krajden Naveed Zafar Janjua Tags: Article Source Type: research
