Expression of Heat Shock Protein 70 (HSP70) and Astacin Genes of < em > Strongyloides stercoralis < /em > as well as HSP70 and HSP17.1 Genes of < em > S. ratti < /em > in Adult and Larval Stages of < em > S. stercoralis < /em >

CONCLUSION: Higher expression levels of Sst-ast, Sst-hsp-70, and Sra-hsp-70 genes in the larval stages of S. stercoralis suggest the potential role of these enzymes in parasite cutaneous invasion and pathogenesis. However, higher expression of Srahsp-17.1 in adult forms is probably involved in resistance and survival mechanisms. The similarity in gene expression between S. stercoralis and S. ratti can provide helpful hints to better understand strongyloidiasis from various perspectives, including pathogenesis, proper diagnosis, and targeted treatment.PMID:38654956 | PMC:PMC11033530 | DOI:10.18502/ijpa.v19i1.15187
Source: Iranian Journal of Parasitology - Category: Parasitology Authors: Source Type: research