Modulation of host immune status by cryptococcus co-infection during HIV-1 pathogenesis and its impact on CD+4 cell and cytokines environment
ConclusionThere are very limited studies related to the immune modulation status of HIV co-infected with Cryptococcus before the initiation of any drug therapy. Such information might through in-depth light to understand the initial state of the immune environment which certainly would play a pivotal role in the outcome of the immune modulation. (Source: Microbial Pathogenesis)
Source: Microbial Pathogenesis - November 10, 2019 Category: Infectious Diseases Source Type: research

A primary investigation of the relation between the incidence of brucellosis and climatic factors in Iran
Publication date: Available online 8 November 2019Source: Microbial PathogenesisAuthor(s): Maryam Dadar, Youcef Shahali, Yadolah FakhriAbstractBrucella spp. Is Gram-negative coccobacilli that may grow in different media and environmental conditions for extended periods of time. The survivals of these bacteria in the environment have an important impact on the epidemiology of brucellosis worldwide. The effect of climate on the incidence of certain zoonotic infectious diseases, (recently referred to as climate-sensitive zoonosis) is now well established. The aim of this study was to evaluate the relation between the incidenc...
Source: Microbial Pathogenesis - November 10, 2019 Category: Infectious Diseases Source Type: research

Measures of frequency used in cohorts studies to evaluate the suicidal behaviour in young people (12–26 years): A systematic review
ConclusionsResearchers must make an effort to reach an agreement on the measures of frequency used in suicidal behaviour studies, as the methodological and terminological variability currently used impedes making any comparisons between different studies or understanding the real dimension of the problem.ResumenIntroducciónLa OMS prioriza para el año 2020 reducir las tasas de suicidio señalando dificultades para dar estimaciones precisas debido a una amplia variedad de factores, entre ellos, aspectos relativos a la propia medición estadística de la conducta suicida. La proporción d...
Source: Revista de Psiquiatria y Salud Mental - November 10, 2019 Category: Psychiatry Source Type: research

Examining Cell-Cell Interactions in the Kidney Using AFM Single-Cell Force Spectroscopy.
Abstract The ability of individual cells to synchronize activity is a basic feature of efficient and appropriate tissue function. Central to this is the physicochemical binding between cells through multiprotein complexes that functionally mediate adhesion. Importantly, the direct connection of physical properties and intercellular signaling is of great importance to certain pathologies including diabetes. Atomic force microscopy (AFM) single-cell force spectroscopy (SCFS) is a high-resolution technique that provides a statistically reliable measurement of the minute forces involved in cell tethering and membrane ...
Source: Mol Biol Cell - November 10, 2019 Category: Molecular Biology Authors: Siamantouras E, Hills CE, Liu KK, Squires PE Tags: Methods Mol Biol Source Type: research

Biostatistics in Africa 2019: A Special Issue of The International Journal of Biostatistics
Journal Name: The International Journal of Biostatistics Issue: Ahead of print (Source: The International Journal of Biostatistics)
Source: The International Journal of Biostatistics - November 10, 2019 Category: Statistics Source Type: research

Fixing a Fragmented System: Impact of a Comprehensive Geriatric Hip Fracture Program on Long-Term Mortality.
CONCLUSION: Fixing fragmentation in geriatric hip fracture care such as through an orthogeriatric model is essential to improving overall survival for this patient population. PMID: 31702983 [PubMed - in process] (Source: The Permanente journal)
Source: The Permanente journal - November 10, 2019 Category: General Medicine Tags: Perm J Source Type: research

Randomized Study of Systematic Biopsy Versus Magnetic Resonance Imaging and Targeted and Systematic Biopsy in Men on Active Surveillance (ASIST): 2-year Postbiopsy Follow-up
ConclusionsBaseline MRI before CBx during AS results in 50% fewer AS failures and less grade progression over 2 yr. The center where MRI and targeted biopsy is performed may influence AS failure rates.Patient summaryThe ASIST trial randomized 273 men on active surveillance with low-grade prostate cancer diagnosed within the last year to systematic biopsy or magnetic resonance imaging (MRI) with systematic and targeted biopsy. The initial report showed little benefit from targeted biopsy. However, after 2 yr of follow-up we found that baseline MRI before confirmatory biopsy resulted in 50% fewer failures of surveillance...
Source: European Urology - November 10, 2019 Category: Urology & Nephrology Source Type: research

Updated Results of PURE-01 with Preliminary Activity of Neoadjuvant Pembrolizumab in Patients with Muscle-invasive Bladder Carcinoma with Variant Histologies
ConclusionsThe updated PURE-01 results confirm the activity of neoadjuvant pembrolizumab in MIBC. Patients with SCC and LEL features may be suitable for neoadjuvant immunotherapy trials. CPS and TMB are the key response predictors irrespective of the histological subtypes.Patient summaryIn the PURE-01 study, we have preliminarily evaluated the activity of neoadjuvant pembrolizumab in patients with predominant variant histology (VH). Of these patients, those harboring squamous-cell carcinoma or a lymphoepithelioma-like variant feature had major, although preliminary, pathological responses compared with those with other pre...
Source: European Urology - November 10, 2019 Category: Urology & Nephrology Source Type: research

Exploring oral paleopathology in the Central Andes: A review
Publication date: Available online 9 November 2019Source: International Journal of PaleopathologyAuthor(s): Celeste Marie GagnonAbstractThis targeted review of oral paleopathology in the Central Andes explores research that focuses on a set of interrelated, multifactorial processes: dental caries, macrowear, alveolar abscess, antemortem tooth loss (AMTL), periodontal disease, and the presence of dental calculus. These conditions help characterize oral health because they result from the culturally mediated interaction of individuals’ oral cavity with their external environment. To better understand how osteologists w...
Source: International Journal of Paleopathology - November 10, 2019 Category: Pathology Source Type: research

Noninvasive Diagnosis of Adenomyosis: A Structured Review and Meta-Analysis of Diagnostic Accuracy in Imaging
ConclusionAs a result of the systemic review and meta-analysis, we identified TVUS and MRI as good and comparable non-invasive imaging methods for diagnosisng adenomayosis, leading us to recommend TVUS as the first-line diagnostic imagin method and MRI as second if TVUS is inconclusive. (Source: Journal of Minimally Invasive Gynecology)
Source: Journal of Minimally Invasive Gynecology - November 10, 2019 Category: OBGYN Source Type: research

What is status epilepticus and what do we know about its epidemiology?
Publication date: Available online 9 November 2019Source: SeizureAuthor(s): Simon Shorvon, Arjune SenABSTRACTEpidemiological studies across medical conditions share many similar difficulties relating, for instance, to selection bias, defining a population frame, statistical power and adequate documentation. However, in the case of status epilepticus there are, in addition to these, a variety of specific issues that pose significant hurdles to accurate investigation – not least defining status epilepticus itself and determining whether it is simply a severe manifestation of epilepsy or should be considered a distinct ...
Source: Seizure - November 10, 2019 Category: Neurology Source Type: research

Preexisting illness, fetal malformation, and seizure control rates in pregnant women with epilepsy
Publication date: Available online 9 November 2019Source: Epilepsy & BehaviorAuthor(s): Frank John Emery Vajda, Terence John O'Brien, Janet Elizabeth Graham, Alison Anne Hitchcock, Cecilie Margaret Lander, Mervyn John EadieAbstractData from 2182 pregnancies in the Australian Register of antiepileptic drugs in pregnancy that were followed to term, with 1965 followed for another year, were analyzed to ascertain whether preexisting illness influenced i. the hazard of fetal malformations, and ii. seizure control during pregnancy. Fetal malformation occurred in 74 of the 842 pregnancies associated with preexisting illness (...
Source: Epilepsy and Behavior - November 10, 2019 Category: Neurology Source Type: research

Clinical outcomes of endoscopic vs retromandibular approach for the treatment of condylar fractures—a randomized clinical trial
This study, therefore, aims to compare the retromandibular (extraoral) approach and EAORIF for the treatment of condylar fractures.Study DesignA prospective analysis of 32 cases of condylar fractures that reported to the SDM Craniofacial Centre (Dharwad, India) was carried out. Sixteen patients had been treated with the retromandibular (RM) approach, and 16 had undergone EAORIF in the period from 2012–2017. Patients were evaluated for clinical parameters, such as fracture site, displacement, and surgical duration, as well as for functional parameters, such as occlusion, maximum interincisal opening, deviation of mout...
Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology - November 10, 2019 Category: ENT & OMF Source Type: research

Role of wastewater treatment plants on environmental abundance of Antimicrobial Resistance Genes in Chilean rivers.
Abstract BACKGROUND: Point sources such as wastewater treatment plants (WWTPs) commonly discharge their effluent into rivers. Their waste may include antibiotic residues, disinfectants, antibiotic resistant bacteria (ARB), and Antimicrobial Resistance Genes (ARG). There is evidence that ARG can be found in the natural environment, but attribution to specific point sources is lacking. OBJECTIVES: The goal of this study was to assess the release and dissemination of ARG from three WWTPs in southern Chile via two pathways: through the river systems, and through wild birds. METHODS: A longitudinal study was ...
Source: International Journal of Hygiene and Environmental health - November 10, 2019 Category: Environmental Health Authors: Bueno I, Verdugo C, Jimenez-Lopez O, Alvarez PP, Gonzalez-Rocha G, Lima CA, Travis DA, Wass B, Zhang Q, Ishii S, Singer RS Tags: Int J Hyg Environ Health Source Type: research

Population pharmacokinetics of ipilimumab in combination with nivolumab in patients with advanced solid tumors
AbstractIpilimumab is a fully human monoclonal antibody approved for the treatment of melanoma as monotherapy and for the treatment of melanoma, renal cell carcinoma, and colorectal cancer in combination with nivolumab. Ipilimumab time ‐varying clearance (CL) was assessed by a population pharmacokinetics (PPK) model developed using statistically significant covariates identified in a previous PPK analysis plus additional covariates. Data from 3,411 patients who received ipilimumab 0.3–10 mg/kg alone or in combination with niv olumab in 16 clinical trials were analyzed. Ipilimumab CL decreased over time; the ch...
Source: CPT: Pharmacometrics and Systems Pharmacology - November 10, 2019 Category: Drugs & Pharmacology Authors: Kinjal Sanghavi, Jason Zhang, Xiaochen Zhao, Yan Feng, Paul Statkevich, Jennifer Sheng, Amit Roy, Heather E. Vezina Tags: ARTICLE Source Type: research

A hierarchical latent response model for inferences about examinee engagement in terms of guessing and item-level non-response.
Abstract In low-stakes assessments, test performance has few or no consequences for examinees themselves, so that examinees may not be fully engaged when answering the items. Instead of engaging in solution behaviour, disengaged examinees might randomly guess or generate no response at all. When ignored, examinee disengagement poses a severe threat to the validity of results obtained from low-stakes assessments. Statistical modelling approaches in educational measurement have been proposed that account for non-response or for guessing, but do not consider both types of disengaged behaviour simultaneously. We bring...
Source: The British Journal of Mathematical and Statistical Psychology - November 10, 2019 Category: Statistics Authors: Ulitzsch E, von Davier M, Pohl S Tags: Br J Math Stat Psychol Source Type: research

Effect of cycling and functional electrical stimulation with linear and interval patterns of timing on gait parameters in patients after stroke: a randomized clinical trial.
Abstract Objective: Patients in the chronic phase after a stroke are an underrepresented group in the literature. Therefore, the aim of this study was to compare the effects of cycling and functional electrical stimulation with linear versus interval patterns of timing on gait parameters in patients after stroke.Design: A double blinded, parallel, randomized clinical trial.Setting: Neuroscience Institute.Participants: Patients with lower limb disability due to stroke (N = 30) with a stroke onset>6 months and
Source: Disability and Rehabilitation - November 10, 2019 Category: Rehabilitation Authors: Shariat A, Nakhostin Ansari N, Honarpishe R, Moradi V, Hakakzadeh A, Cleland JA, Kordi R Tags: Disabil Rehabil Source Type: research

Population pharmacokinetics of ipilimumab in combination with nivolumab in patients with advanced solid tumors
AbstractIpilimumab is a fully human monoclonal antibody approved for the treatment of melanoma as monotherapy and for the treatment of melanoma, renal cell carcinoma, and colorectal cancer in combination with nivolumab. Ipilimumab time ‐varying clearance (CL) was assessed by a population pharmacokinetics (PPK) model developed using statistically significant covariates identified in a previous PPK analysis plus additional covariates. Data from 3,411 patients who received ipilimumab 0.3–10 mg/kg alone or in combination with niv olumab in 16 clinical trials were analyzed. Ipilimumab CL decreased over time; the ch...
Source: CPT: Pharmacometrics and Systems Pharmacology - November 10, 2019 Category: Drugs & Pharmacology Authors: Kinjal Sanghavi, Jason Zhang, Xiaochen Zhao, Yan Feng, Paul Statkevich, Jennifer Sheng, Amit Roy, Heather E. Vezina Tags: ARTICLE Source Type: research

Review of Prediabetes and Hypertensive Disorders of Pregnancy
Am J Perinatol DOI: 10.1055/s-0039-1698831Obesity and diabetes increase hypertensive disorders of pregnancy (HDP) risk, thus preventive interventions are heavily studied. How pregestational prediabetes and related interventions impact HDP risk is less characterized. Therefore, we searched and reviewed the literature to assess the impact on HDP risk of prediabetes and varied interventions. We identified 297 citations related to pregnancy, prediabetes, and early pregnancy interventions. We also reviewed the references and citations of included articles. We included five studies assessing HDP outcomes in women with first trim...
Source: American Journal of Perinatology - November 10, 2019 Category: Perinatology & Neonatology Authors: Carris, Nicholas W. Nwabuobi, Chinedu K. He, Weiwei Bullers, Krystal Wilson, Rone é E. Louis, Judette M. Magness, Ronald R. Tags: Review Article Source Type: research

Effect of Photobiomodulation on Repairing Pressure Ulcers in Adult and Elderly  Patients: A Systematic Review
Pressure ulcers are highly prevalent among adult and elderly patients where risk factors vary. In addition to guidelines to the conventional treatment, some auxiliary therapies such as photobiomodulation have shown promising results in wound healing. In this systematic review, only 5 papers were selected according to the eligibility criteria of this research. It was observed that PBMT red wavelength, similar to standard care, promoted tissue repair with a reduced lesion area. AbstractEvaluation of photobiomodulation therapy (PBMT) in the treatment of pressure ulcers in adults and the elderly. Systematic review, based on th...
Source: Photochemistry and Photobiology - November 10, 2019 Category: Science Authors: Francislene de Fatima Cordeiro Petz, Jorge Vinicius Cestari F élix, Hellen Roehrs, Franciele Soares Pott, Janislei Giseli Dorociaki Stocco, Rodrigo Labat Marcos, Marineli Joaquim Meier Tags: Research Article Source Type: research

Potential Benefits of Laparoscopic Repair of Duodenal Atresia: Insights from a Retrospective Comparative Study
Conclusion Patients undergoing laparoscopic CDO repair at our institution benefited from shorter time to full enteral feeds, and reduced the need for PN as well as postoperative pain medication. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - November 10, 2019 Category: Surgery Authors: Sidler, Martin Djendov, Florin Curry, Joe I. Blackburn, Simon Giuliani, Stefano Eaton, Simon Mullassery, Dhanya Cross, Kate M. De Coppi, Paolo Tags: Original Article Source Type: research

Sinomenine hydrochloride exerts antitumor outcome in ovarian cancer cells by inhibition of long non-coding RNA HOST2 expression.
Conclusion: Our findings recommended that SH exerted the antitumor effect in ovarian cancer cells by hindering expression of HOST2. PMID: 31701766 [PubMed - in process] (Source: Artificial Cells, Nanomedicine and Biotechnology)
Source: Artificial Cells, Nanomedicine and Biotechnology - November 9, 2019 Category: Biotechnology Tags: Artif Cells Nanomed Biotechnol Source Type: research

Automated high-throughput tensile testing reveals stochastic process parameter sensitivity
This study seeks to understand how automated high throughput testing can be utilized to understand the variable nature of additively manufactured metals at different print conditions, and to allow for statistically meaningful analysis. This is demonstrated by analyzing how different processing parameters, including laser power, scan velocity, and scan pattern, influence the tensile behavior of additively manufactured stainless steel 316L utilizing a newly developed automated test methodology. Microstructural characterization through computed tomography and electron backscatter diffraction is used to understand some of the ...
Source: Materials Science and Engineering: A - November 9, 2019 Category: Materials Science Source Type: research

Effect of coke rate and basicity on computed tomography-measured pore parameters and effective thermal conductivity of iron ore sinter
This study aimed to compare differences in X-ray computed tomography (XCT) measured pore parameters, and examine relationships between pore parameters and sinter effective thermal conductivity based on actual structure. Nine sinter samples (three coke rates multiply three basicity levels) were carefully prepared from pilot-scale sinter pot tests and scanned by XCT with the resolution ratio of 40 μm. The results demonstrate that higher coke rate and basicity promote melt formation during sintering, transforming sinter from particulate structure to melt-bonded structure. Under the tested conditions, sinter porosity i...
Source: Journal of Materials Research and Technology - November 9, 2019 Category: Materials Science Source Type: research

Bayesian approach and time series dimensionality reduction to LSTM-based model-building for fault diagnosis of a reciprocating compressor
Publication date: Available online 8 November 2019Source: NeurocomputingAuthor(s): Diego Cabrera, Adriana Guamán, Shaohui Zhang, Mariela Cerrada, René-Vinicio Sánchez, Juan Cevallos, Jianyu Long, Chuan LiAbstractReciprocating compression machinery is the primary source of compressed air in the industry. Undiagnosed faults in the machinery’s components produce a high rate of unplanned stoppage of production processes that can even result in catastrophic consequences. Fault diagnosis in reciprocating compressors requires complex and time-consuming feature-extraction processes because typical fault ...
Source: Neurocomputing - November 9, 2019 Category: Neuroscience Source Type: research

Redox state of adipose tissue for patients with gastric cancer and its connection with the body mass index and distance from the tumor
Publication date: Available online 9 November 2019Source: Obesity Research & Clinical PracticeAuthor(s): A.P. Burlaka, I.I. Ganusevich, A.V. Vovk, A.A. Burlaka, M.R. Gafurov, S.N. LukinAbstractExcess body weight has been causally linked to an increased risk of different cancer types, including gastric cancer but the mechanisms underlying this relationship are not well understood. Superoxide generation rate, activity of complex I in electron transport chain of mitochondria, activity of matrix metalloproteinase (MMP-2 and 9) of adipose tissues (AT) of patients with gastric cancer in AT located adjacent to tumor (ATAT) an...
Source: Obesity Research and Clinical Practice - November 9, 2019 Category: Eating Disorders & Weight Management Source Type: research

Predictors of 30-day Mortality in ST-Elevation Myocardial Infarction (STEMI) Patients.
CONCLUSION: There are two new score variables that can be used as predictors of 30-day mortality risks for STEMI patients, i.e. the Killip class and GFR with satisfactory calibration and discrimination rate. PMID: 31699947 [PubMed - in process] (Source: Acta medica Indonesiana)
Source: Acta medica Indonesiana - November 9, 2019 Category: Internal Medicine Tags: Acta Med Indones Source Type: research

Tadalafil Once a Day for Men with Erectile Dysfunction: Is It Superior than On-Demand Administration?
CONCLUSION: administration of tadalafil OAD leads to a better improvement of EF compared to PRN administration. PMID: 31699953 [PubMed - in process] (Source: Acta medica Indonesiana)
Source: Acta medica Indonesiana - November 9, 2019 Category: Internal Medicine Tags: Acta Med Indones Source Type: research

[How do renal function and dilation change after pieloplasty surgery in children?]
Authors: Carrillo-Arroyo I, Tordable-Ojeda C, Cabezalí-Barbancho D, Morante-Valverde R, Gómez-Fraile A Abstract OBJECTIVE: The effects of pyeloplasty on renal function are not fully well defined. Our objective is to determine if renal function and renal dilation change after pyeloplasty and the risk factors that may influence in both parameters. METHODS: Retrospective study of patients who underwent pyeloplasty. The parameters analyzed included: age, differential renal function, renal dilation, infection and complications. We compared ultrasound findings with measurement of the anterior-posterior ...
Source: Archivos Espanoles de Urologia - November 9, 2019 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

[Second-line treatment in recurrent urinary incontinence after the use of mid-urethral tapes. Systematic review and metaanalysis of proportions.]
CONCLUSION: The evidence found shows that there may be superiority of the adjustable tapes versus the mid urethral tapes and other included treatments. However, a comparison to statistically corroborate this difference could not be made. These results should be confirmed with multicenter collaborative randomized clinical trials. PMID: 31697249 [PubMed - in process] (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - November 9, 2019 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

The analgesic efficacy of ultrasound guided unilateral transversus abdominis plane block in the pain management of shock wave lithotripsy.
CONCLUSION: Pain relief during SWL operations is still a challenging issue for many clinicians. Our study demonstrates that, among many other anesthetic/analgesic agents and techniques described, unilateral US guided TAP block and diclofenac combination is a feasible option for pain relief during SWL procedures. PMID: 31697254 [PubMed - in process] (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - November 9, 2019 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

Understanding the characteristics of sequence-based single-source DNA profiles
Publication date: Available online 9 November 2019Source: Forensic Science International: GeneticsAuthor(s): Sarah Riman, Hari Iyer, Lisa A. Borsuk, Peter M. ValloneAbstractThe sequencing of STR markers provides additional information present in the underlying sequence variation that is typically masked by traditional fragment-based genotyping. However, the interpretation of STR profiles generated by targeted sequencing methods are susceptible to the same factors encountered in profiles processed through capillary gel electrophoresis. These factors include stochastic variation, noise, stutter artifacts, heterozygote imbala...
Source: Forensic Science International: Genetics - November 9, 2019 Category: Forensic Medicine Source Type: research

Analysis of a DNAmixture case involving Romani reference populations
Publication date: Available online 9 November 2019Source: Forensic Science International: GeneticsAuthor(s): Francesco Dotto, Julia Mortera, Laura Baldassarri, Vincenzo PascaliAbstractHere we present an Italian criminal case that shows how statistical methods can be used to extract information from a series of mixed DNA profiles. The case involves several different individuals and a set of different DNA traces. The case possibly involves persons of interest of a small population of Romani origin. First, a brief description of the case is provided. Secondly, we introduce some heuristic tools that can be used to evaluate the...
Source: Forensic Science International: Genetics - November 9, 2019 Category: Forensic Medicine Source Type: research

Epidemiological investigations of Crimean-Congo haemorrhagic fever virus infection in sheep and goats in Balochistan, Pakistan
Publication date: Available online 9 November 2019Source: Ticks and Tick-borne DiseasesAuthor(s): Khushal Khan Kasi, Miriam Andrada Sas, Carola Sauter-Louis, Felicitas von Arnim, Jörn Martin Gethmann, Ansgar Schulz, Kerstin Wernike, Martin H. Groschup, Franz J. ConrathsAbstractCrimean-Congo haemorrhagic fever (CCHF) is a tick-borne zoonotic disease caused by the arbovirus Crimean-Congo haemorrhagic fever virus (CCHFV). Livestock serve as a transient reservoir for CCHFV, but do not show clinical signs. In this cross-sectional study, sheep and goats in Balochistan, Pakistan, were examined to determine the CCHFV seroprev...
Source: Ticks and Tick borne Diseases - November 9, 2019 Category: Zoology Source Type: research

Effect of the nutritional status of Creole goats on the density-dependent prolificacy of Haemonchus contortus
In conclusion, this reduced establishment rate was associated with an increased production of eggs by the female parasites and suggested a phenomenon of density-dependent prolificacy of H. contortus probably inherent to the fitness of the parasite population. (Source: Veterinary Parasitology)
Source: Veterinary Parasitology - November 9, 2019 Category: Veterinary Research Source Type: research

3_D surface stereometry of Ag/DLC nanocomposite prepared by RF-PECVD
In this study, a stereometric analysis of the three-dimensional (3-D) surfaces of the Ag/diamond-like carbon (DLC) nanocomposite films was done. The nanocomposite thin films were fabricated by Radio Frequency Plasma-Enhanced Chemical Vapour Deposition (RF-PECVD). The 3-D surface microtexture was studied by high-resolution Atomic Force Microscopy (AFM) records combined with statistical analyses. More detailed information about surface statistical parameters and topographic features of analyzed samples were performed. The statistical parameters relating to the segmented motifs consistent with ISO 25178-2: 2012 have been gene...
Source: Results in Physics - November 9, 2019 Category: Physics Source Type: research

Unfolding pathway and its identifiability in heterogeneous chains of bistable units
Publication date: Available online 9 November 2019Source: Physics Letters AAuthor(s): Manon Benedito, Stefano GiordanoAbstractWe investigate the behavior of a chain of bistable units with an heterogeneous distribution of energy jumps between the folded and unfolded states. For homogeneous chains, loaded by soft or hard devices, all units at each switching occurrence have the same probability to unfold and it is therefore impossible to identify an unfolding pathway. Conversely, the heterogeneity represents a quenched disorder from the statistical mechanics point of view, and is able to break the symmetry eventually generati...
Source: Physics Letters A - November 9, 2019 Category: Physics Source Type: research

Reasons for Abortion: Religion, Religiosity/Spirituality and Attitudes of Male Secondary School Youth in South Africa
This study focused on the relationship between religion, religiosity/spirituality (R/S), and attitudes of a sample of South African male secondary school youth toward women ’s rights to legal abortion in different situations. We distributed 400 self-administered questionnaires assessing the main variables (attitudes toward reasons for abortion and R/S) to the target sample in six different secondary schools in KwaZulu-Natal, South Africa. The responses of a final sam ple of 327 learners were then analyzed using the Statistical Package for the Social Sciences (SPSS) software. The findings revealed that religion and R/...
Source: Journal of Religion and Health - November 9, 2019 Category: Medical Ethics Source Type: research

Tracing life at the dry limit using phospholipid fatty acids – does sampling matter?
Publication date: Available online 8 November 2019Source: Soil Biology and BiochemistryAuthor(s): Stephanie Kusch, Andrea Jaeschke, Ramona Mörchen, Janet RethemeyerAbstractPhospholipid fatty acids (PLFAs) have been used to trace bacterial life in extremely carbon-poor soils of the hyperarid Atacama Desert. However, the low abundances of bacteria and, thus, PLFAs increases the risk of contamination by exogenous PLFAs. Here, we assess whether field sampling strategies (super-clean, clean, and regular sampling protocols) have an effect on PLFA diversity and abundance in hyperarid Atacama soils or whether laboratory proce...
Source: Soil Biology and Biochemistry - November 9, 2019 Category: Biology Source Type: research

Low concentrations of acetylcarvacrol induce drastic morphological damages in ovaries of surviving Rhipicephalus sanguineus sensu lato ticks (Acari: Ixodidae)
Publication date: Available online 8 November 2019Source: MicronAuthor(s): Isaac Filipe Moreira Konig, Marcos Vinícius Silva de Oliveira, Raquel Romano Palmeira Gonçalves, Ana Paula Peconick, Sérgio Scherrer Thomasi, Luís Adriano Anholeto, José Ribamar Lima-de-Souza, Maria Izabel Camargo-Mathias, Rafael Neodini RemedioAbstractRhipicephalus sanguineus sensu lato (s. l.) ticks are targets of acaricidal treatments due to their great veterinary and medical importance. Acetylcarvacrol stands out as a promising acaricidal substance for its increased biocidal activity and stability. Additionally...
Source: Micron - November 9, 2019 Category: Biology Source Type: research

Consistency and identifiability of the polymorphism-aware phylogenetic models
Publication date: Available online 8 November 2019Source: Journal of Theoretical BiologyAuthor(s): Rui Borges, Carolin KosiolAbstractPolymorphism-aware phylogenetic models (PoMo) constitute an alternative approach for species tree estimation from genome-wide data. PoMo builds on the standard substitution models of DNA evolution but expands the classic alphabet of the four nucleotide bases to include polymorphic states. By doing so, PoMo accounts for ancestral and current intra-population variation, while also accommodating population-level processes ruling the substitution process (e.g. genetic drift, mutations, allelic se...
Source: Journal of Theoretical Biology - November 9, 2019 Category: Biology Source Type: research

Robust extended Kalman filter based state estimation for nonlinear dynamic processes with measurements corrupted by gross errors
Publication date: Available online 9 November 2019Source: Journal of the Taiwan Institute of Chemical EngineersAuthor(s): Guiting Hu, Zhengjiang Zhang, Antonios Armaou, Zhengbing YanAbstractThe quality of on-line measurement data usually cannot meet the demands of practical process monitoring and control due to the influence of measurement noise. Although extended Kalman filter (EKF) is able to improve the quality by reconciling the measurement data to fit the dynamic process model describing nonlinear and Gaussian processes, it rarely considers the presence of different types of gross errors, such as outliers, bias and dr...
Source: Journal of the Taiwan Institute of Chemical Engineers - November 9, 2019 Category: Chemistry Source Type: research

Analysis of spatio-temporal rainfall trends across southern African biomes between 1981 and 2016
In this study, we simultaneously examined spatial and temporal rainfall trends based on the space-time rainfall cube derived from 1981 to 2016 CHIRPS satellite rainfall data. The space time rainfall trend analysis revealed a significant (P 
Source: Physics and Chemistry of the Earth, Parts ABC - November 9, 2019 Category: Science Source Type: research

Row over tactical voting site
Publication date: 9 November 2019Source: New Scientist, Volume 244, Issue 3255Author(s): James BallCampaigners under fire for their statistical model for tactical voting (Source: New Scientist)
Source: New Scientist - November 9, 2019 Category: Science Source Type: research

Image-stitching artefacts and distortion in CCD-based cephalograms and their association with sensor type and head movement: ex vivo study.
CONCLUSION: Sensor type, movement type, distance, and pattern affected presence and severity of image-stitching artefacts and distortion in CCD-based cephalograms. PMID: 31697180 [PubMed - as supplied by publisher] (Source: Dentomaxillofacial Radiology)
Source: Dentomaxillofacial Radiology - November 9, 2019 Category: Radiology Tags: Dentomaxillofac Radiol Source Type: research

Development and Testing of a Brief Play Space Audit Tool.
CONCLUSIONS: This brief instrument allows reliable assessment of playground features and their conditions. The scoring method generates a summary of playground conditions and features, which facilitates comparison of playgrounds. This tool has the potential to assist communities in evaluating their play spaces and identifying where to focus resources for improvements. PMID: 31698335 [PubMed - as supplied by publisher] (Source: Journal of Physical Activity and Health)
Source: Journal of Physical Activity and Health - November 9, 2019 Category: Sports Medicine Tags: J Phys Act Health Source Type: research

Warm-Up With Dynamic Stretching: Positive Effects on Match-Measured Change of Direction Performance in Young Elite Volleyball Players.
Authors: Turki O, Dhahbi W, Padulo J, Khalifa R, Ridène S, Alamri K, Milić M, Gueid S, Chamari K Abstract PURPOSE: To explore the immediate (15-s post-warm-up) and the delayed (after 20 and 40 min of simulated volleyball play) effects of 2 different warm-up protocols-a stretching-free volleyball warm-up (NS) and a warm-up incorporating dynamic stretching (DS)-on subsequent change of direction (COD) performance in young elite volleyball players. METHODS: Sixteen male players (age 16.88 [0.34] y, body mass 75.81 [5.41] kg, body height 1.91 [0.05] m, body mass index 20.84 [1.79] kg...
Source: International Journal of Sports Physiology and Performance - November 9, 2019 Category: Sports Medicine Tags: Int J Sports Physiol Perform Source Type: research

Efficacy of monoclonal anti-tumour necrosis factor- α antibodies in uveitic macular oedema.
Efficacy of monoclonal anti-tumour necrosis factor-α antibodies in uveitic macular oedema. Clin Exp Rheumatol. 2019 Oct 17; Authors: Tosi GM, Vitale A, Rigante D, Sota J, Emmi G, Lopalco G, Guerriero S, Iannone F, Vannozzi L, Bitossi A, Frediani B, Cantarini L, Fabiani C Abstract OBJECTIVES: To assess the efficacy of anti-tumour necrosis factor (TNF)-α agents in the treatment of refractory uveitic macular oedema (UME). METHODS: Patients with refractory UME treated with TNF-α blockers were retrospectively enrolled. Central macular thickness (CMT) was assessed at optical coherence t...
Source: Clinical and Experimental Rheumatology - November 9, 2019 Category: Rheumatology Tags: Clin Exp Rheumatol Source Type: research

Association of apolipoprotein B/apolipoprotein A1 ratio and cardiovascular events in rheumatoid arthritis: results of the CARMA study.
CONCLUSIONS: No association between ApoB/apoA1 ratio and CVE was found at the baseline visit of patients with RA from the CARMA study. PMID: 31694752 [PubMed - as supplied by publisher] (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - November 9, 2019 Category: Rheumatology Tags: Clin Exp Rheumatol Source Type: research

Long-term survival of lung transplantation for interstitial lung disease associated with connective tissue diseases: a study of 26 cases from a referral centre.
CONCLUSIONS: Long-term post-transplant survival in Northern Spanish patients with CTD-ILD is reduced compared with IPF. PMID: 31694743 [PubMed - as supplied by publisher] (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - November 9, 2019 Category: Rheumatology Tags: Clin Exp Rheumatol Source Type: research