A Comparison of the Circulating Endocan Levels between the Inflammatory and Malignant Diseases of the Same Organ: The Breast.
CONCLUSIONS: We demonstrated that the serum endocan level was increased in patients with BC compared to healthy subjects, whereas in our enrolled study patient population, endocan was not a statistically valid biomarker for the differential diagnosis between BC and IGM. These findings indicate the potential role of endocan in the pathogenesis of BC. PMID: 32660374 [PubMed - as supplied by publisher] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - July 16, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

The effect of human papilloma virus vaccination on embryo yield and clinical in  vitro fertilisation outcomes: a matched retrospective cohort study.
The effect of human papilloma virus vaccination on embryo yield and clinical in vitro fertilisation outcomes: a matched retrospective cohort study. J Obstet Gynaecol. 2020 Jul 14;:1-7 Authors: Demir M, Ince O, Yilmaz B, Decleer W, Osmanagaoglu K Abstract The effects of HPV vaccination on embryo yield and pregnancy outcomes in IVF cycles with fresh embryo transfer (ET) were investigated. First, embryo yielding rates (EYR) in 2795 cycles with and without HPV vaccination were compared by retrospective cohort study design. EYR of HPV vaccinated and non-vaccinated patients were not significantly differ...
Source: Journal of Obstetrics and Gynaecology - July 16, 2020 Category: OBGYN Tags: J Obstet Gynaecol Source Type: research

Recognition Investigation of Community Pharmacists Implementing Good Pharmacy Practice in Korea.
This study aimed to verify, for the first time, the need for Good Pharmacy Practice (GPP) regulations as guidelines to provide pharmaceutical care services in community pharmacies in Korea. Statistical analyses were performed with demographic characteristics, institutional factors, and diversity factors of 3 pharmaceutical care services as independent variables and the favorability of GPP implementation as a dependent variable. In assessing the diversity of methods of providing pharmaceutical care services as an indicator of willingness to provide these services, this study understood such diversity as an innovative behavi...
Source: International Journal of Health Services - July 16, 2020 Category: Health Management Tags: Int J Health Serv Source Type: research

Three-dimensional assessment of the sella turcica: comparison between cleft lip and palate patients and skeletal malocclusion classes
AbstractPurposeThe main aim of the present study was to investigate the dimensions and morphological appearance of the sella turcica in cleft lip and palate patients using cone-beam computed tomography (CBCT) images, compared to non-cleft individuals.MethodsCBCT images of 40 (20 females and 20 males) cleft lip and palate patients and 60 (27 males and 33 females) non-cleft individuals were assessed, retrospectively. The linear dimensions (depth, diameter and length) of the sella turcica and inter-clinoid distance were measured. Sella turcica shapes were examined in the cleft lip and palate patients and non-cleft individuals...
Source: Surgical and Radiologic Anatomy - July 16, 2020 Category: Anatomy Source Type: research

Classification of the midpalatal suture maturation in individuals older than 15 years: a cone beam computed tomographic study
ConclusionNo individuals in stage A of suture maturation were found and stage B was identified in only 1% of the sample. The majority of the patients (64.88%) presented at least partial fusion of the MPS (stages D and E). (Source: Surgical and Radiologic Anatomy)
Source: Surgical and Radiologic Anatomy - July 16, 2020 Category: Anatomy Source Type: research

Pica Disorder among African American Women: A Call for Action and Further Research.
This article provides a panoramic overview of Pica, the signs and symptoms of the disorder specifically among African American women and also address some of the adverse effects, and highlights some of the evidence-based effective treatment strategies. Finally, an urgent clarion call to social workers to conduct more research on Pica disorders among African American women is articulated. PMID: 32660362 [PubMed - as supplied by publisher] (Source: Social Work in Public Health)
Source: Social Work in Public Health - July 15, 2020 Category: International Medicine & Public Health Tags: Soc Work Public Health Source Type: research

Painless and painful synovitis have similar ultrasound and clinical outcomes: one-year cohort study in longstanding rheumatoid arthritis women patients.
Authors: Pereira DF, Natour J, Ribeiro LHC, Ferreira FBMD, Fernandes ARC, Furtado RNV Abstract OBJECTIVES: We aimed to compare the painless synovitis evolution with painful synovitis, based on bone erosion by ultrasonography over a year in women with longstanding rheumatoid arthritis. Ultrasound inflammatory measurements and radiographic, functional and clinical findings were also compared between groups at the end of the same follow-up. METHODS: A prospective cohort study was rolled out, involving 60 women with RA, divided into two groups: painless and painful, with 30 patients in each group. The wrist and MCP...
Source: Clinical and Experimental Rheumatology - July 15, 2020 Category: Rheumatology Tags: Clin Exp Rheumatol Source Type: research

Circulating leptin level, soluble leptin receptor level and their gene polymorphism in patients with systemic lupus erythematosus: a systematic review and meta-analysis.
CONCLUSIONS: Our meta-analysis revealed thta SLE patients had an elevated leptin level and decreased LepR level. LepR gene rs1137101 mutation might be associated with increased susceptibility to SLE. PMID: 32662402 [PubMed - as supplied by publisher] (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - July 15, 2020 Category: Rheumatology Tags: Clin Exp Rheumatol Source Type: research

Anti-carbamylated protein antibodies: are they useful for the diagnosis of rheumatoid arthritis?
CONCLUSIONS: For RA classification, anti-CarP+ was less sensitive than ACPA, but more specific than RF. Anti-CarP+ may prove useful, classifying early arthritis patients, notably ACPA- patients. PMID: 32662401 [PubMed - as supplied by publisher] (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - July 15, 2020 Category: Rheumatology Tags: Clin Exp Rheumatol Source Type: research

Effects of Intraligamentary Injection of Osteogenic-Induced Gingival Fibroblasts on Cementum Thickness in the Dog Model of Tooth Root Resorption.
Authors: El-Bialy T, Hazan Molina H, Aizenbud Y, Qayyum W, Ali S, Aizenbud D Abstract Tooth root resorption is an unwanted result of orthodontic tooth movement, and it can be expressed by a reduction in cementum thickness. The aim of this experimental study was to evaluate the effect of intraligamentary injection of osteogenic-induced gingival fibroblasts (OIGF) on cellular and acellular tooth root cementum thickness in modeled orthodontic tooth movement. Six beagle dogs were used in the study. All the upper and lower third and fourth premolars were subjected to mechanical loading for 4 weeks, which induced or...
Source: Advances in Experimental Medicine and Biology - July 15, 2020 Category: Research Tags: Adv Exp Med Biol Source Type: research

Crocin enhances the viability of random pattern skin flaps: involvement of enhancing angiogenesis and inhibiting oxidative stress.
Authors: Cai L, Xie L, Dong Q Abstract The random pattern skin flap has been an important procedure in plastic and reconstructive surgery to cover various challenging defects. However, distal flap necrosis is problematic. Crocin is a natural carotenoid compound, which have been reported to possess a wide spectrum of properties and induce pleiotropic anti-inflammatory, anti-oxidative and cytoprotective effects. We explored whether crocin enhanced random skin flap survival. Thirty-six male SD rats were distributed to two groups randomly: the crocin and control groups. Flap survival areas were measured 7 days after su...
Source: American Journal of Translational Research - July 15, 2020 Category: Research Tags: Am J Transl Res Source Type: research

Aberrant promoter methylation of NOTCH1 and NOTCH3 and its association with cervical cancer risk factors in North Indian population.
Authors: Kadian LK, Gulshan G, Ahuja P, Singhal G, Sharma S, Nanda S, Yadav R Abstract Cervical cancer is the fourth most common type of cancer in women worldwide, and associated mortality is highest in developing countries like India. Limited studies are available on the role of NOTCH signaling pathway and promoter methylation in cervical cancer. In the current study, we investigated the promoter methylation status of NOTCH receptor genes (mainly NOTCH1, NOTCH2, and NOTCH3) and its correlation with gene expression, clinicopathological factors, and prognosis of cervical cancer. A total cohort of 110 cervical cancer...
Source: American Journal of Translational Research - July 15, 2020 Category: Research Tags: Am J Transl Res Source Type: research

Physiological factors which influence the performance potential of athletes:Analysis of sports medicine performance testing in Nordic combined.
CONCLUSION: In this study, test speed on the treadmill [m/s] at a lactate concentration of 4 mmol/l showed the strongest influence that was independent of other parameters on the sporting performance of the Nordic combined athletes. Regardless of how the lactate threshold is determined, a lactate value of 4 mmol/l should almost always be above an indicative anaerobic threshold, meaning that the application of this parameter is more valid than using an arbitrary individual threshold, both physiologically and mathematically. In this vein, the test speed at a lactate concentration of 4 mmol/l can be recommended as a robuster,...
Source: The Physician and Sportsmedicine Online - July 15, 2020 Category: Sports Medicine Tags: Phys Sportsmed Source Type: research

Relation between mutations in the 5' UTR of ANKRD26 gene and inherited thrombocytopenia with predisposition to myeloid malignancies. An Egyptian study.
Authors: Zidan NI, AbdElmonem DM, Elsheikh HM, Metwally EA, Mokhtar WA, Osman GM Abstract Inherited thrombocytopenias are a heterogeneous group of diseases characterized by a reduced number of platelets and a bleeding tendency that ranges from very mild to life threatening especially in surgery. Mutations in the 5' untranslated region (UTR) of Ankirin repeat domain 26 (ANKRD26) are responsible for autosomal-dominant form of thrombocytopenia, that is known as ANKRD26-related thrombocytopenia (ANKRD26 RT), characterized by a moderate thrombocytopenia with mild propensity to bleeding and predisposition to hematologica...
Source: Platelets - July 15, 2020 Category: Hematology Tags: Platelets Source Type: research

Novel Cytokine Multiplex Assay for Tear Fluid Analysis in Sjogren's Syndrome.
Authors: Willems B, Tong L, Minh TDT, Pham ND, Nguyen XH, Zumbansen M Abstract PURPOSE: Sjögren's syndrome (SS) is an autoimmune disease associated with ocular surface inflammation. The goals of this study were to establish a novel bead-based protein microarray for simultaneous analysis of 11 cytokines from tear fluid collected with Schirmer strips from patients with SS. METHODS: Three to ten microliter of tear fluid was collected with Schirmer strips from both eyes of 13 healthy controls and 12 SS patients. Tear fluid was eluted from the Schirmer strips, total protein and concentrations of 11 different cy...
Source: Ocular Immunology and Inflammation - July 15, 2020 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

[Recanalisation by Probing with a Bicanalicular Silicone Tube (Oggel Silicone Intubation) in Patients with Acquired Lacrimal Stenosis].
CONCLUSION: The results allow a prognostic assessment of the therapeutic success in the absence of significant differences in the subgroups. The therapeutic success of bicanalicular silicone intubation with the Oggel tube was in the lower third of comparable studies. The results conform to the observation that there is a progressive decline of therapeutic success. The comparison of the literature turned out to be methodically more difficult due to differences in study characteristics. Standardisation would make sense for future studies. PMID: 32659841 [PubMed - as supplied by publisher] (Source: Klinische Monatsblatter fur Augenheilkunde)
Source: Klinische Monatsblatter fur Augenheilkunde - July 15, 2020 Category: Opthalmology Tags: Klin Monbl Augenheilkd Source Type: research

Alveolar Ridge Regeneration of Damaged Extraction Sockets using a Bovine-derived Bone Graft in Association with a Titanium Foil: Prospective Case Series.
CONCLUSION: Bovine bone graft in association with Tseal achieved horizontal reconstruction of the alveolar crest in compromised socket within 6 months after surgery. PMID: 32655036 [PubMed - in process] (Source: Journal of the International Academy of Periodontology)
Source: Journal of the International Academy of Periodontology - July 15, 2020 Category: Dentistry Tags: J Int Acad Periodontol Source Type: research

Development of new predictive equations for basal metabolic rate in Iranian healthy adults: negligible effect of sex.
In conclusion, there were statistical significant under- and over-estimation of RMR using common predictive equations in our subjects. Using the new equations, the accuracy of the calculated RMR increased remarkably. PMID: 32654630 [PubMed - as supplied by publisher] (Source: International Journal for Vitamin and Nutrition Research)
Source: International Journal for Vitamin and Nutrition Research - July 15, 2020 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

On the Use of Sampling Weights for Retrospective Medical Record Reviews.
This article aims to fill that gap and to demonstrate why the use of sample weights ought to be another best practice to add to the list by reviewing well-known theoretical details and some published data analysis examples. PMID: 32663124 [PubMed - as supplied by publisher] (Source: The Permanente journal)
Source: The Permanente journal - July 15, 2020 Category: General Medicine Tags: Perm J Source Type: research

Seroprevalence of West Nile virus in Khuzestan province, southwestern Iran, 2016-2017.
Authors: Kalantari M, Salehi-Vaziri M, Pouriayevali MH, Baniasadi V, Salmanzadeh S, Kharat M, Fazlalipour M Abstract BACKGROUND & OBJECTIVES: West Nile virus (WNV) is a neurotropic Flavivirus transmitted to humans through mosquito bites. As there is no specific antiviral treatment or approved vaccine against WNV, control and prevention of the infection is the best strategy to reduce the burden of WNV-related diseases. The circulation of WNV has been indicated in several regions of Iran including the Khuzestan province. Considering the complex ecology of WNV, the latest data are necessary for the implementation ...
Source: Journal of Vector Borne Diseases - July 15, 2020 Category: Infectious Diseases Tags: J Vector Borne Dis Source Type: research

The Relationship between C-Reactive Protein/Albumin Ratio and Disease Activity in Patients with Inflammatory Bowel Disease.
Authors: Chen YH, Wang L, Feng SY, Cai WM, Chen XF, Huang ZM Abstract Objectives: The aims of this study were to evaluate the C-reactive protein/albumin ratio (CRP/ALB), inflammatory markers, and parameters from the complete blood count (CBC) in patients with inflammatory bowel disease (IBD) and their associations with disease activity. Methods: A total of 876 IBD patients, composed of 275 patients with ulcerative colitis (UC) and 601 patients with Crohn's disease (CD), were included in this retrospective study, and the serum C-reactive protein (CRP), albumin (ALB), erythrocyte sedimentation rate (ESR), and CBC...
Source: Gastroenterology Research and Practice - July 15, 2020 Category: Gastroenterology Tags: Gastroenterol Res Pract Source Type: research

Sea Buckthorn and Grape Antioxidant Effects in Hyperlipidemic Rats: Relationship with the Atorvastatin Therapy.
Authors: Mohamed EA, Bordean DM, Radulov I, Moruzi RF, Hulea CI, Orășan SA, Dumitrescu E, Muselin F, Herman H, Brezovan D, Hermenean A, Cristina RT Abstract Background: Medications to reduce oxidative stress are preventing cellular damage associated with hyperlipidemia. In this regard, statins (e.g., atorvastatin) act primarily by decrease in low-density lipoprotein-c but, in the last decade, hepatotoxicity, associated with liver injuries in the next months after treatments' initiation, was reported. In this case, associated phytotherapy can be a solution. Purpose: To investigate the antioxidant potential and...
Source: Evidence-based Complementary and Alternative Medicine - July 15, 2020 Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research

Acute and 28-Day Repeated-Dose Oral Toxicity Assessment of Abelmoschus moschatus Medik. in Healthy Wistar Rats.
Authors: Amarasiri SS, Attanayake AP, Arawwawala LDAM, Jayatilaka KAPW, Mudduwa LKB Abstract Abelmoschus moschatus Medik. (family: Malvaceae) has a long history of being used as a folk medicine in Sri Lanka. Despite the therapeutic use of this plant in traditional medicine, leaves of A. moschatus have not been subjected to scientific evaluation of toxicity/adverse effects in vivo. Thus, the present study was aimed to assess the acute and 28-day repeated-dose oral toxic effects of hexane (55 mg/kg), ethyl acetate (75 mg/kg), butanol (60 mg/kg), and aqueous (140 mg/kg) leaf extracts of A. ...
Source: Evidence-based Complementary and Alternative Medicine - July 15, 2020 Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research

Early changes in NT-proBNP levels predict new-onset heart failure in patients with STEMI.
CONCLUSIONS: NT-proBNP level at 72 hours and ΔNT-proBNP (72 hours minus admission), but not at time of admission, predicted HF events in patients following STEMI. PMID: 32657561 [PubMed - as supplied by publisher] (Source: Minerva Cardioangiologica)
Source: Minerva Cardioangiologica - July 15, 2020 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

Atherosclerotic Extension of Carotid Arteries: An Insertion in Clinical Practice.
Conclusion: Therefore, our study proposes an improvement in the clinical approach of patients with PAD for both the carotid and coronary territory, not using only 2 factors traditional risk factors, for the extension study and to consider the PAD that has 10% dependence alone, as effect and projection of the carotid atherosclerotic plaque. PMID: 32655952 [PubMed] (Source: International Journal of Vascular Medicine)
Source: International Journal of Vascular Medicine - July 15, 2020 Category: Cardiology Tags: Int J Vasc Med Source Type: research

Regional differences in healthcare costs at the end of life: an observational study using Swiss insurance claims data
ConclusionsBoth supply factors and health-service provision at the EOL vary between Swiss language regions and explain a substantial proportion of cost differences. (Source: International Journal of Public Health)
Source: International Journal of Public Health - July 15, 2020 Category: International Medicine & Public Health Source Type: research

Complementary And Alternative Medicine Use In Turkish Patients With Epilepsy.
Abstract Context: Epilepsy is a condition characterized by abnormal and excessive electrical discharges of cortical neurons resulting sudden, repetitive, event-triggered seizures. Epilepsy is most common neurologic disorder during childhood and the second most common neurological disorder following cerebrovascular diseases in adults. Use of CAM in persons with epilepsy is high, even compared to individuals with other chronic health conditions. Objectives: We aimed to determine the prevalence, types, and factors influencing use of complementary and alternative medicine (CAM) in adults with epilepsy. Metho...
Source: Alternative Therapies in Health and Medicine - July 15, 2020 Category: Complementary Medicine Authors: Tan M, Kavurmaci M Tags: Altern Ther Health Med Source Type: research

Deformational Plagiocephaly and Reduced Cervical Range of Motion: A Pediatric Case Series in a Chiropractic Clinic.
Conclusion: The presence of plagiocephaly was associated with a higher prevalence of restriction in cervical PROM. A statistically significant association existed between restriction of the occipitoatlantal joint and development of contralateral deformational plagiocephaly. Future clinical trials assessing the effectiveness of spinal manipulative therapy in the treatment and management of restricted cervical PROM and plagiocephaly in infants are needed. PMID: 32663178 [PubMed - as supplied by publisher] (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - July 15, 2020 Category: Complementary Medicine Authors: Fludder CJ, Keil BG Tags: Altern Ther Health Med Source Type: research

Devoid Knowledge and Low Adherence Precipitate Uncontrolled Blood Pressure: A Depiction From Cross-Sectional Study.
Abstract Objective: The present study was aimed to assess knowledge regarding disease, adherence to medication and blood pressure control among hypertensive patients. Methods: A cross-sectional study involving 384 hypertensive patients attending a tertiary care, public sector hospital in Islamabad, Pakistan, was conducted. Data was collected by using Urdu versions of pre-validated hypertension knowledge questionnaire and Medication Adherence Scale by Morisky. Each patient's blood pressure was measured through a calibrated mercury sphygmomanometer. Data was analyzed statistically by using SPSS software version...
Source: Alternative Therapies in Health and Medicine - July 15, 2020 Category: Complementary Medicine Authors: Amer M, Ur Rehman N, Nazir SUR, Ehsan-Ul-Haq M, Sultana M, Jabeen M Tags: Altern Ther Health Med Source Type: research

A new integrated approach to cardiac mechanics: reference values for normal left ventricle
AbstractThe association between left ventricular (LV) myocardial deformation and hemodynamic forces is still mostly unexplored. The normative values and the effects of demographic and technical factors on hemodynamic forces are not known. The authors studied the association between LV myocardial deformation and hemodynamic forces in a large cohort of healthy volunteers. One-hundred seventy-six consecutive subjects (age range, 16 –82; 51% women), with no cardiovascular risk factors or any relevant diseases, were enrolled. All subjects underwent an echo-Doppler examination. Both 2D global myocardial and endocardial lon...
Source: The International Journal of Cardiovascular Imaging - July 15, 2020 Category: Radiology Source Type: research

Did “Conduce Sin Alcohol” a Program that Monitors Breath Alcohol Concentration Limits for Driving in Mexico City Have an Effect on Traffic-Related Deaths?
AbstractIn September 2003, Mexico City introduced “Conduce sin Alcohol” (CSA)-drive without alcohol-a program that monitors breath alcohol concentration limits among drivers to reduce road traffic crashes. To our knowledge, no study has evaluated the impact of this program on mortality. We estimated the effect of CSA on the monthly rate of traf fic-related deaths (deaths per one million people) in Mexico City. We applied interrupted time series analyses (ITSA) using monthly data from 1998 to 2016, adjusting for number of people covered by a public health insurance, monthly number of public health care facilitie...
Source: Prevention Science - July 15, 2020 Category: Psychiatry & Psychology Source Type: research

Evaluation of Disease Related Knowledge in Patients of Osteoporosis: An Observational Study.
This study was aimed to assess the knowledge of osteoporosis among patients in tertiary healthcare systems, as well as their knowledge of associated lifestyle, risk factors, and preventive measures. Methods: A cross-sectional study design was used to determine the knowledge of outpatients towards osteoporosis. The survey was carried out in a tertiary care hospital Federal Government Polyclinic Hospital, Islamabad. This study included patients visiting various outpatient departments of Federal Government Polyclinic Hospital, Islamabad. A structured questionnaire was used as a tool to collect the data from the participa...
Source: Alternative Therapies in Health and Medicine - July 15, 2020 Category: Complementary Medicine Authors: Amer M, Noor S, Kashif SM, Nazir SUR, Ghazanfar T, Yousaf S Tags: Altern Ther Health Med Source Type: research

COVID-19 pandemic: management of patients affected by SARS-CoV-2 in Rome COVID Hospital 2 Trauma Centre and safety of our surgical team
ConclusionsMore studies are needed to provide a higher statistical significance to the safety measures taken in order to contrast the spread of SARS-CoV-2 in the Surgical Room. Orthopaedic surgeons are more exposed to the contagion due to the particular tools set they use. A more sensible and specific quick test for novel Coronavirus is particularly needed, due to the lack of sensitivity of the serological rapid test. (Source: International Orthopaedics)
Source: International Orthopaedics - July 15, 2020 Category: Orthopaedics Source Type: research

Comparative analysis of magnetic resonance imaging and pathological findings of microcystic meningioma and meningeal Ewing sarcoma/peripheral primitive neuroectodermal tumors
AbstractMicrocystic meningiomas (MCMs) and meningeal Ewing sarcoma/peripheral primitive neuroectodermal tumours (pPNETs) are difficult to differentiate because of the similarity in their image manifestation on magnetic resonance imaging (MRI). Differential diagnosis of these two tumours before surgery could contribute to ameliorating clinical decision-making, and predicting prognosis. Here, we aimed to comparatively analyse the difference between MRI and pathological findings of these two tumours. Thirteen cases of MCM and eleven cases of meningeal Ewing sarcoma/pPNET confirmed through pathology were analysed retrospective...
Source: Acta Neurologica Belgica - July 15, 2020 Category: Neurology Source Type: research

Simultaneous Augmentation Mammoplasty and Vacuum-Assisted Breast Biopsy for Enhanced Cosmesis and Efficacy
ConclusionSimultaneous augmentation mammoplasty and VABB prevented unnecessary scars and pain, and the complication rates did not statistically differ from those of augmentation only group. This co-operation is a safe and simple method potentially beneficial to many women interested in breast surgery.Level of Evidence IIIThis journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authorswww.springer.com/00266. (Source: Aesthetic Plastic Surgery)
Source: Aesthetic Plastic Surgery - July 15, 2020 Category: Cosmetic Surgery Source Type: research

Prognostic Factors Influencing Survival Rate of Patients Operated for Prostate-Related Metastatic Spinal Cord Compression (MSCC)
AbstractProstate-related metastatic spinal cord compression (MSCC) accounts for 50% of all MSCC cases and constitute an oncological emergency. Metastatic spread has a detrimental impact on patient quality of life and the whole management strategy. We sought to identify the prognostic factors influencing the survival rate of patients operated for prostate-related MSCC. Sixty medical records of patients operated for prostate-related MSCC were selected from January 2002 to December 2014 in the Neurosurgery Department, Yopougon Teaching Hospital, Abidjan, Ivory Coast. Tokuhashi and Karnofsky scales were used to assess prognost...
Source: Indian Journal of Surgical Oncology - July 15, 2020 Category: Cancer & Oncology Source Type: research

IJERPH, Vol. 17, Pages 5115: Forecasting Covid-19 Dynamics in Brazil: A Data Driven Approach
Marcos Garcia Gonçalves The contribution of this paper is twofold. First, a new data driven approach for predicting the Covid-19 pandemic dynamics is introduced. The second contribution consists in reporting and discussing the results that were obtained with this approach for the Brazilian states, with predictions starting as of 4 May 2020. As a preliminary study, we first used an Long Short Term Memory for Data Training-SAE (LSTM-SAE) network model. Although this first approach led to somewhat disappointing results, it served as a good baseline for testing other ANN types. Subsequently, in order to identify re...
Source: International Journal of Environmental Research and Public Health - July 15, 2020 Category: Environmental Health Authors: Igor Gadelha Pereira Joris Michel Guerin Andouglas Gon çalves Silva Júnior Gabriel Santos Garcia Prisco Piscitelli Alessandro Miani Cosimo Distante Luiz Marcos Garcia Gon çalves Tags: Article Source Type: research

Molecules, Vol. 25, Pages 3234: Aronia melanocarpa Fruits as a Rich Dietary Source of Chlorogenic Acids and Anthocyanins: 1H ‑NMR, HPLC-DAD, and Chemometric Studies
Molecules, Vol. 25, Pages 3234: Aronia melanocarpa Fruits as a Rich Dietary Source of Chlorogenic Acids and Anthocyanins: 1H‑NMR, HPLC-DAD, and Chemometric Studies Molecules doi: 10.3390/molecules25143234 Authors: Agnieszka Zielińska Paweł Siudem Katarzyna Paradowska Małgorzata Gralec Sławomir Kaźmierski Iwona Wawer Aronia melanocarpa (Michx.) Elliott's (chokeberry) besides anthocyanins contains significant amounts of hydroxycinnamic acids: Chlorogenic and its isomer neochlorogenic acid. They exhibit antioxidant, anti-inflammatory, antidiabetic, and antibacterial activities, thus they can have...
Source: Molecules - July 15, 2020 Category: Chemistry Authors: Agnieszka Zieli ńska Pawe ł Siudem Katarzyna Paradowska Ma łgorzata Gralec S ławomir Kaźmierski Iwona Wawer Tags: Article Source Type: research

IJERPH, Vol. 17, Pages 5119: The Association between Race and Survival among Pediatric Patients with Neuroblastoma in the US between 1973 and 2015
Conclusions: No association between race and survival time was found. However, survival improved among all patients treated during 2000–2004 and 2005–2015 compared with those treated before the year 2000, leading to a narrowing of the racial disparity based on survival. (Source: International Journal of Environmental Research and Public Health)
Source: International Journal of Environmental Research and Public Health - July 15, 2020 Category: Environmental Health Authors: Farouk S. Farouk Omar A. Viqar Zaid Sheikh Grettel Castro No ël C. Barengo Tags: Article Source Type: research

The metabolism and swimming performance of sheepshead minnows ( Cyprinodon variegatus ) following thermal acclimation or acute thermal exposure
AbstractEctothermic animals are especially susceptible to temperature change, considering that their metabolism and core temperature are linked to the environmental temperature. As global water temperatures continue to increase, so does the need to understand the capacity of organisms to tolerate change. Sheepshead minnows (Cyprinodon variegatus) are the most eurythermic fish species known to date and can tolerate a wide range of environmental temperatures from − 1.9 to 43.0 °C. But little is known about the physiological adjustments that occur when these fish are subjected to acute thermal challenges...
Source: Journal of Comparative Physiology B: Biochemical, Systemic, and Environmental Physiology - July 15, 2020 Category: Physiology Source Type: research

Streptococcus mutans Secreted Products Inhibit Candida albicans Induced Oral Candidiasis
In this study, we extracted and fractioned culture filtrate of S. mutans, seeking antifungal agents capable of inhibiting the biofilms, filamentation, and candidiasis by Candida albicans. Active S. mutans UA159 supernatant filtrate components were extracted via liquid-liquid partition and fractionated on a C-18 silica column to resolve S. mutans fraction 1 (SM-F1) and fraction 2 (SM-F2). We found anti-biofilm activity for both SM-F1 and SM-F2 in a dose dependent manner and fungal growth was reduced by 2.59 and 5.98 log for SM-F1 and SM-F2, respectively. The SM-F1 and SM-F2 fractions were also capable of reducing C. albican...
Source: Frontiers in Microbiology - July 15, 2020 Category: Microbiology Source Type: research

Ventricular assist devices and middle age reduce heart transplantation rates for waitlist candidates
AbstractBackgroundVentricular assist devices (VADs) are commonly employed as a bridge to transplantation for heart failure. The full effects of VADs on transplantation rates are not fully understood. We sought to compare transplantation rates stratified by age and VAD status.MethodsUsing the Organ Procurement and Transplantation Network (OPTN) database, we investigated the impact of age and VAD status on heart allocation rates among all transplant ‐eligible patients from January 2005 to September 2018. Patients were grouped based on the presence (+) or absence (−) of a VAD as well as age (65 years). Demographics we...
Source: Journal of Cardiac Surgery - July 15, 2020 Category: Cardiovascular & Thoracic Surgery Authors: James J. Whitbread, Eric W. Etchill, Katherine A. Giuliano, Alejandro I. Suarez ‐Pierre, Jennifer S. Lawton, Steven Hsu, Chun W. Choi, Robert S. D. Higgins, Ahmet Kilic Tags: ORIGINAL ARTICLE Source Type: research

Analysis of Differentially Expressed Genes and Molecular Pathways in Familial Hypercholesterolemia Involved in Atherosclerosis: A Systematic and Bioinformatics Approach
This study focused on identifying the dysregulated molecular pathways and core genes that are differentially regulated in FH and to identify the possible genetic factors and potential underlying mechanisms that increase the risk to atherosclerosis in patients with FH.Methods: The Affymetrix microarray dataset (GSE13985) from the GEO database and the GEO2R statistical tool were used to identify the differentially expressed genes (DEGs) from the white blood cells (WBCs) of five heterozygous FH patients and five healthy controls. The interaction between the DEGs was identified by applying the STRING tool and visualized using ...
Source: Frontiers in Genetics - July 15, 2020 Category: Genetics & Stem Cells Source Type: research

Potential therapeutic and prophylactic effects of Asafoetida in murine cryptosporidiosis
This study aims to test the potential therapeutic and prophylactic effects of a natural herbal agent (Asafoetida) versus the nowadays drug of choice (Nitazoxanide). Fifty bred female, white Albino mice of CDI strain were divided into 5 groups;group I (GI): immunosuppressed, infected withC. parvum and treated with Asafoetida,group II (GII): immunosuppressed, prophylactically treated with Asafoetida for 7  days prior to infection,group III (GIII): immunosuppressed, infected and treated with Nitazoxanide,group IV (GIV): immunosuppressed and infected (Positive control),group V (GV): immunosuppressed and non infected (Nega...
Source: Journal of Parasitic Diseases - July 15, 2020 Category: Parasitology Source Type: research

Indigenous technique as an effective liquid-based cytology tool for multiple single-layered cell preparations
Conclusion: Monolayer preparation by MMT is cheap and effective. This technique can be used in routine laboratory for multiple monolayer cell preparations. (Source: Journal of Cytology)
Source: Journal of Cytology - July 15, 2020 Category: Cytology Authors: Shelly Sharma Pranab Dey Source Type: research

Evaluation of role of intraoperative cytology technique in diagnosis and management of cancer
Conclusion: Intraoperative imprint/crush cytology is a simple, inexpensive, rapid, accurate cytodiagnostic technique in the diagnosis of cancer where frozen section facilities are not available. It can also be used to assess the clearance of surgical margins. (Source: Journal of Cytology)
Source: Journal of Cytology - July 15, 2020 Category: Cytology Authors: Yashika P Jaiswal Rasika U Gadkari Source Type: research

Contaminants and mimickers in cytopathology
Conclusions: Contaminants and mimickers can make the evaluation of cytologic specimens challenging and may necessitate secondary review by another pathologist or further workup. Knowledge and familiarity of these commonly encountered extraneous substances will help to prevent misinterpretation. (Source: Journal of Cytology)
Source: Journal of Cytology - July 15, 2020 Category: Cytology Authors: S Muzarath Sonam S Nandyal BJ Bindu C Narayana Murthy Source Type: research

IJERPH, Vol. 17, Pages 5105: Spatio-Temporal Dynamics of Tick-Borne Diseases in North-Central Wisconsin from 2000 –2016
IJERPH, Vol. 17, Pages 5105: Spatio-Temporal Dynamics of Tick-Borne Diseases in North-Central Wisconsin from 2000–2016 International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17145105 Authors: Austin Rau Claudia Munoz-Zanzi Anna M. Schotthoefer Jonathan D. Oliver Jesse D. Berman Lyme disease is a well-recognized public health problem in the USA, however, other tick-borne diseases also have major public health impacts. Yet, limited research has evaluated changes in the spatial and temporal patterns of non-Lyme tick-borne diseases within endemic regions. Using laboratory dat...
Source: International Journal of Environmental Research and Public Health - July 15, 2020 Category: Environmental Health Authors: Austin Rau Claudia Munoz-Zanzi Anna M. Schotthoefer Jonathan D. Oliver Jesse D. Berman Tags: Article Source Type: research

Effect of Resistance Training on Arterial Stiffness in Healthy Subjects: A Systematic Review and Meta-Analysis
AbstractPurpose of ReviewThe aim of this systematic review and meta-analysis was to investigate the effect of resistance training on arterial stiffness (AS) in healthy subjects. Two electronic databases (PubMed and Scielo) were searched for randomized controlled trials comparing the effect of dynamic and/or isometric resistance training stand-alone versus non-exercise control group on AS assessed by pulse wave velocity (PWV) in healthy subjects. Random-effects modeling was employed to compare delta changes (post –pre-intervention) in AS between the resistance training and control group. Data were reported as weighted...
Source: Current Hypertension Reports - July 15, 2020 Category: Primary Care Source Type: research

Pilot Observational Study to Detect Diurnal Variation and Misalignment in Heart Rate Among Critically Ill Patients
Circadian disruption is common in critically ill patients admitted to the intensive care unit (ICU). Understanding and treating circadian disruption in critical illness has significant potential to improve critical illness outcomes through improved cognitive, immune, cardiovascular, and metabolic function. Measurement of circadian alignment (i.e., circadian phase) can be resource-intensive as it requires frequent blood or urine sampling over 24 or more hours. Less cumbersome methods of assessing circadian alignment would advance investigations in this field. Thus, the objective of this study is to examine the feasibility o...
Source: Frontiers in Neurology - July 15, 2020 Category: Neurology Source Type: research