An Investigation on the c ‐MYC, AXIN1, and COL11A1 gene expression in colorectal cancer
This article is protected by copyright. All rights reserved (Source: Biotechnology and Applied Biochemistry)
Source: Biotechnology and Applied Biochemistry - July 29, 2021 Category: Biochemistry Authors: Shirin Moradifard, Zarrin Minuchehr, Shahla Mohammad Ganji Tags: Original Article Source Type: research

BRAIN HEALTH ASSESSMENT IN MACULAR DEGENERATION PATIENTS UNDERGOING INTRAVITREAL ANTI–VASCULAR ENDOTHELIAL GROWTH FACTOR INJECTIONS (THE BHAM STUDY): An Interim Analysis
Conclusion: Our study is the first to associate worsening cognitive health with higher cumulative anti-VEGF injections. This study was not designed to show a causal link, but does suggest that additional investigation is warranted. (Source: RETINA)
Source: RETINA - July 29, 2021 Category: Opthalmology Tags: Original Study Source Type: research

Phacovitrectomy versus lens-sparing vitrectomy for rhegmatogenous retinal detachment repair according to the surgical experience
Purpose: To compare the efficacy and safety between lens-sparing vitrectomy and phacovitrectomy for primary rhegmatogenous retinal detachment treatment according to surgical experience. Methods: We retrospectively reviewed the medical records of 193 patients with primary rhegmatogenous retinal detachment who underwent either lens-sparing vitrectomy (n = 111) or phacovitrectomy (n = 82). Patients were operated by two experienced surgeons or eight vitreoretinal fellows and had a minimum follow-up of 6 months. Anatomical success rate, postoperative complications, and functional outcomes were compared. Results: ...
Source: RETINA - July 29, 2021 Category: Opthalmology Tags: Original Study Source Type: research

Assessing refractive outcomes and accuracy of biometry in phacovitrectomy and sequential operations in patients with retinal detachment compared with routine cataract surgery
Purpose: To compare refractive outcomes and accuracy of modern optical biometry, swept-source optical coherence tomography, ultrasound biometry, and effect of the macula status in rhegmatogenous retinal detachment managed with either combined phacovitrectomy or sequential vitrectomy and cataract surgery compared with a control, phacoemulsification alone. Methods: Retrospective, comparative, consecutive study of 154 eyes; Group 1 underwent phacovitrectomy (n: 70), Group 2 underwent vitrectomy with subsequent cataract surgery (n: 41), and Group 3 underwent cataract surgery alone (n: 43). Results: No differe...
Source: RETINA - July 29, 2021 Category: Opthalmology Tags: Original Study Source Type: research

Natural course of vitreomacular traction in eyes with diabetic retinopathy and factors associated with spontaneous release
Conclusion: Spontaneous release of VMT observed higher rates of patients without hyperreflective retinal spots, epiretinal membrane, and patients with lower horizontal length of VMT. (Source: RETINA)
Source: RETINA - July 29, 2021 Category: Opthalmology Tags: Original Study Source Type: research

POSITIVE RESULTS BIAS AND IMPACT FACTOR IN RETINA CLINICAL TRIALS 2016 to 2019
Conclusion: These results do not support the presence of a recent positive results bias in retina randomized controlled trials. This is reassuring, although several factors could be contributing to this finding including studies that were conducted but never submitted and selective reporting of outcomes. Thus, it will be important to remain cognizant of potential publication biases moving forward. (Source: RETINA)
Source: RETINA - July 29, 2021 Category: Opthalmology Tags: Original Study Source Type: research

GSE179417 CXCL1: A new diagnostic biomarker for human tuberculosis discovered using Diversity Outbred mice
Contributors : Deniz Koyuncu ; B ülent Yener ; Gillian BeamerSeries Type : Expression profiling by arrayOrganism : Mus musculusMore humans have died of tuberculosis (TB) than any other infectious disease and millions still die each year. Experts advocate for blood-based, protein biomarkers to help diagnosis TB, which is critical in high-burden countries. However, the protein biomarker pipeline is small. Here, we used the Diversity Outbred (DO) mouse population to address this gap, identifying five protein biomarker candidates. One biomarker, serum CXCL1, met the World Health Organization ’s Targeted Product Prof...
Source: GEO: Gene Expression Omnibus - July 29, 2021 Category: Genetics & Stem Cells Tags: Expression profiling by array Mus musculus Source Type: research

Sensors, Vol. 21, Pages 5147: Comparison of Two Electronic Physical Performance Batteries by Measurement Time and Sarcopenia Classification
Conclusion: Breakdowns of eSPPB test times were identified. Omitting balance tests may reduce test time without significantly affecting the classifying ability of eSPPB for sarcopenia. (Source: Sensors)
Source: Sensors - July 29, 2021 Category: Biotechnology Authors: Chan Mi Park Hee-Won Jung Il-Young Jang Ji Yeon Baek Seongjun Yoon Hyunchul Roh Eunju Lee Tags: Brief Report Source Type: research

Sensors, Vol. 21, Pages 5134: Latest Research Trends in Fall Detection and Prevention Using Machine Learning: A Systematic Review
emin Park Falls are unusual actions that cause a significant health risk among older people. The growing percentage of people of old age requires urgent development of fall detection and prevention systems. The emerging technology focuses on developing such systems to improve quality of life, especially for the elderly. A fall prevention system tries to predict and reduce the risk of falls. In contrast, a fall detection system observes the fall and generates a help notification to minimize the consequences of falls. A plethora of technical and review papers exist in the literature with a primary focus on fall detection...
Source: Sensors - July 29, 2021 Category: Biotechnology Authors: Sara Usmani Abdul Saboor Muhammad Haris Muneeb A. Khan Heemin Park Tags: Review Source Type: research

IJERPH, Vol. 18, Pages 8009: Influence of Pharmaceutical Copayment on Emergency Hospital Admissions: A 1978 –2018 Time Series Analysis in Spain
In conclusion, the PCS did not influence hospital admission rates. More studies are needed to design health policies that strike a balance between the amount contributed by the taxpayer and hospital admission rates. (Source: International Journal of Environmental Research and Public Health)
Source: International Journal of Environmental Research and Public Health - July 29, 2021 Category: Environmental Health Authors: Antonio Palaz ón-Bru Miriam Calvo-P érez Pilar Rico-Ferreira Mar ía Anunciación Freire-Ballesta Vicente Francisco Gil-Guill én Mar ía de los Ángeles Carbonell-Torregrosa Tags: Article Source Type: research

What about the Rest of Them? Fatal Injuries Related to Production Agriculture Not Captured by the Bureau of Labor Statistics (BLS) Census of Fatal Occupational Injuries (CFOI)
. (Source: Journal of Agromedicine)
Source: Journal of Agromedicine - July 29, 2021 Category: Environmental Health Authors: Bryan Weichelt Erika Scott Rick Burke John Shutske Serap Gorucu Wayne Sanderson Murray Madsen Emily Redmond Dennis J. Murphy Risto Rautiainen Source Type: research

Real-World Safety and Effectiveness of Golimumab in Rheumatic Diseases: Post-Marketing Surveillance in Korea
ConclusionIn the real-world setting, golimumab was safe and effective in Korean patients with RA, PsA, and AS. (Source: Rheumatology and Therapy)
Source: Rheumatology and Therapy - July 29, 2021 Category: Rheumatology Source Type: research

Assessment of the Effect of Erenumab on Efficacy and Quality-of-Life Parameters in a Cohort of Migraine Patients With Treatment Failure in Cyprus
This study assessed, in a real-world setting, the efficacy of erenumab and its impact on the quality of life (QoL) of Cypriot migraine patients who had failed several treatments in the past. Erenumab was prescribed as a stand-alone or as an add-on therapy to 16 patients with chronic migraine. The first component of the study examined migraine parameters before and after erenumab therapy and included an interim 3-month subjective assessment. In the second component, the patients were asked to complete the validated Migraine-Specific Quality-of-Life Questionnaire—Version 2.1 (MSQ V2.1) during the last month of their in...
Source: Frontiers in Neurology - July 29, 2021 Category: Neurology Source Type: research

B-po02-081 leveraging a cloud based artificial intelligence engine to analyze data from real af registry
Real-AF is a multicenter prospective atrial fibrillation ablation (AFA) registry. CARTONET is a cloud-based solution embedding artificial intelligence (AI) algorithms that allow for procedural data aggregation and statistical analysis. (Source: Heart Rhythm)
Source: Heart Rhythm - July 28, 2021 Category: Cardiology Authors: Joshua R. Silverstein, Jose Osorio, Paul C. Zei, Allyson L. Varley, Brett A. Gidney Source Type: research

Morphological Lesion Types Are Associated with Primary and Secondary Patency Rates after High-Pressure Balloon Angioplasty for Dysfunctional Arteriovenous Fistulas
Conclusions: NIH-dominant lesions of AVF evaluated by DU preoperatively were a risk factor for poor primary and secondary patency rate after PTA in hemodialysis patients.Blood Purif (Source: Blood Purification)
Source: Blood Purification - July 28, 2021 Category: Hematology Source Type: research

Treatment and posttreatment effects of Herbst appliance therapy on trabecular structure of the mandible using fractal dimension analysis
Eur J Orthod. 2021 Jul 28:cjab048. doi: 10.1093/ejo/cjab048. Online ahead of print.ABSTRACTOBJECTIVES: This controlled study aimed to evaluate the effects of Herbst therapy on the trabecular structure of the condyle and angulus mandible using fractal dimension analysis (FD-A) accompanied by skeletal cephalometric changes.MATERIAL AND METHOD: The panoramic and cephalometric radiographs of 30 patients with skeletal Class II malocclusion treated with the Herbst appliance (C II-H group, mean age: 15.23 ± 1.08), 30 patients with skeletal Class II malocclusion that received fixed orthodontic treatment (C II-C group, mean ...
Source: European Journal of Orthodontics - July 28, 2021 Category: Dentistry Authors: Mehmet Amuk Nisa Gul Amuk Serkan Y ılmaz Source Type: research

Comparison of objective wear time between monoblock and twin-block appliances measured by microsensor
CONCLUSIONS: Despite their different designs, there was no significant difference between the monoblock and twin-block appliances in terms of compliance.PMID:34319376 | DOI:10.2319/021421-128.1 (Source: The Angle Orthodontist)
Source: The Angle Orthodontist - July 28, 2021 Category: Dentistry Authors: Cans ın Kutay H ülya Kılıçoğlu G ülşilay Sayar Source Type: research

Association between diastolic stress test and H2FPEF score
CONCLUSIONS: Although clinical scores such as H2FPEF help identify patients, a high percentage of patients are classified in the intermediate range. The diastolic stress test can help to make the diagnosis of diastolic function in this group of patients.PMID:34320623 | DOI:10.24875/ACM.21000053 (Source: Archivos de Cardiologia de Mexico)
Source: Archivos de Cardiologia de Mexico - July 28, 2021 Category: Cardiology Authors: Jairo A Rend ón-Giraldo Camila Lema Clara I Saldarriaga-Giraldo Source Type: research

Automated treatment planning of prostate stereotactic body radiotherapy with focal boosting on a fast-rotating O-ring linac: Plan quality comparison with C-arm linacs
CONCLUSIONS: Automated planning of prostate SBRT with focal boosting on the fast-rotating O-ring linac is feasible and achieves similar plan quality as those obtained on clinical C-arm linacs using manual planning.PMID:34318996 | DOI:10.1002/acm2.13345 (Source: Clinical Prostate Cancer)
Source: Clinical Prostate Cancer - July 28, 2021 Category: Cancer & Oncology Authors: Robin De Roover Wouter Crijns Kenneth Poels Bertrand Dewit C édric Draulans Karin Haustermans Tom Depuydt Source Type: research

The prostate health index and the percentage of [-2]proPSA maintain their diagnostic performance when calculated with total and free PSA from different manufacturers
In this study, 237 men (PSA: 2-10 μg/L) scheduled for prostate biopsy were enrolled. %[-2]proPSA and PHI were calculated with total and free PSA from three manufacturers. Beckman Coulter PSA and [-2]proPSA were performed on the Access 2 analyzer (Hybritech calibration). Roche PSA was performed on the cobas e411 and the Abbott PSA on the Architect i2000sr. Statistical analysis was performed, considering prostate cancer (PCa) as the outcome.RESULTS: Univariate analysis showed that all indices were predictors of cancer, irrespective of the manufacturer (p
Source: Clinical Prostate Cancer - July 28, 2021 Category: Cancer & Oncology Authors: Manuel M Garrido Ruy Ribeiro Lu ís C Pinheiro Stefan Holdenrieder Jo ão T Guimarães Source Type: research

Improving Self-Confidence of Military Medical Providers With Joint Procedure Simulation: A Pilot Study
Mil Med. 2021 Jul 28:usab319. doi: 10.1093/milmed/usab319. Online ahead of print.ABSTRACTINTRODUCTION: Military medical providers are a unique population that encounter different environments across the world. From hospital clinics to war zones, these providers must perform procedures and rely on their training and skill to help their patients. This pilot study aimed to assess the self-confidence of military medical providers performing joint aspiration and injection before and after a simulation workshop in both clinical and austere settings.METHODS: In 2016, 25 military physicians from various military facilities partici...
Source: Military Medicine - July 28, 2021 Category: International Medicine & Public Health Authors: Victoria M F Mank Zhaohui Arter Jeffrey Mank Ki Suk Eum Jefferson Roberts Source Type: research

Visuomotor Synchronization: Military Normative Performance
CONCLUSION: This large-scale quantification of attention, using dynamic visuomotor synchronization performance, provides rigorously characterized age- and sex-based military population norms. This study establishes analytics for assessing normal and impaired attention and detecting changes within individuals over time. Practical applications for combat readiness and surveillance of attention impairment from sleep insufficiency, concussion, medication, or attention disorders will be enhanced with portable, easily accessible, fast, and reliable dynamic eye-tracking technologies.PMID:34318327 | DOI:10.1093/milmed/usab320 (Sou...
Source: Military Medicine - July 28, 2021 Category: International Medicine & Public Health Authors: Jun Maruta Lisa A Spielman Jamshid Ghajar Source Type: research

Comparing the Effect of Heat and Cold Therapy on the Intensity of Nitrate Induced Migraine Type Headache in Cardiac Inpatients: A Randomized Controlled Trial
CONCLUSION: This study demonstrated applying heat and cold therapy may reduce the intensity of nitrate induced migraine type headache in cardiac inpatients. Considering this fact that approximately 10% of patients cannot tolerate nitrate therapies due to unbearable headache, applying heat or cold therapy in patients with nitrate induced migraine type headache is recommended to improve patient's adherence to treatment.PMID:34318912 | DOI:10.14744/agri.2020.00907 (Source: Agri Dergisi)
Source: Agri Dergisi - July 28, 2021 Category: Anesthesiology Authors: Aynaz Bagherzadi Roghiyeh Emani Haleh Ghavami Hamid Reza Khalkhali Marziyeh Ebrahimi Source Type: research

The Long-Term Effects of Plasma Disc Coagulation Therapy for Cervical Disc Hernia
Agri. 2021 Jul;33(3):176-182. doi: 10.14744/agri.2020.28482.ABSTRACTOBJECTIVES: Recently, plasma disc coagulation therapy (PDCT) has been used in the treatment of lumbar and cervical disc hernia (CDH), but the long-term effects of PDCT have not been well documented. The aim of this study was to assess the long-term effects of PDCT on pain score, disc volume and patient satisfaction in patients with CDH.METHODS: Eighty patients with CDH, who underwent PDCT treatment, were included in the study. The patients demographics and pain scores (visual analog scale-VAS) were recorded on the baseline and in the 1st, 3rd, 6th and 12th...
Source: Agri Dergisi - July 28, 2021 Category: Anesthesiology Authors: Sibel Özcan Arzu Muz Serhat Taskin Ahmet K ürşat Poyraz Selami Ates Onal Source Type: research

The Effect of Circadian Rhytm in Patients Undergoing Spinal Anesthesia
CONCLUSIONS: We found out that the time to first analgesic request after spinal anesthesia was significantly longer in Group 1 than in Group 2.PMID:34318918 | DOI:10.14744/agri.2021.65807 (Source: Agri Dergisi)
Source: Agri Dergisi - July 28, 2021 Category: Anesthesiology Authors: Gamze Kili çarslan Metin Alkan Ömer Kurtipek Yusuf Unal Volkan Şıvgın Kursat Dikmen Semin Turhan Mustafa Arslan Source Type: research

Neurocognitive, Quality of Life, and Behavioral Outcomes for Patients With Covert Stroke After Cardiac Surgery: Exploratory Analysis of Data From a Prospectively Randomized Trial
CONCLUSIONS: More than one-half of patients undergoing cardiac surgery demonstrated covert stroke. In this exploratory analysis, covert stroke was not found to be significantly associated with neurocognitive dysfunction 1 month after surgery; evidence of impaired quality of life, anxiety, or depression, albeit a type II error, cannot be excluded.PMID:34319914 | DOI:10.1213/ANE.0000000000005690 (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - July 28, 2021 Category: Anesthesiology Authors: Choy Lewis Annabelle Levine Lauren C Balmert Liqi Chen Saadia S Sherwani Alexander J Nemeth Jordan Grafman Rebecca Gottesman Charles H Brown Charles W Hogue Source Type: research

Investigating diagnosis, treatment, and burden of disease in patients with ankylosing spondylitis in Central Eastern Europe and the United States: a real-world study
Clin Rheumatol. 2021 Jul 28. doi: 10.1007/s10067-021-05864-8. Online ahead of print.ABSTRACTINTRODUCTION/OBJECTIVES: Ankylosing spondylitis (AS) is a chronic inflammatory immune-mediated condition. We compared AS diagnosis, treatment, and burden in Central Eastern European countries (CEE), where this has been less researched, and the United States (US) from a real-world perspective.METHODS: Point-in-time survey of rheumatologists and their AS patients was conducted in the US (Apr-Oct 2018) and CEE (Aug-Nov 2019) via physician- and patient-completed record forms, including clinical and patient-reported outcomes. Statistical...
Source: Pain Physician - July 28, 2021 Category: Anesthesiology Authors: T Korotaeva O Dina E Holdsworth L Fallon G Milligan S Meakin L Wang R Vasilescu J C Cappelleri A Deodhar Source Type: research

Utility of anti-neutrophil cytoplasmic antibody screening in idiopathic interstitial lung disease
CONCLUSION: ANCA screening in patients with idiopathic ILD rarely yields positive results. These results support an individualized approach to ANCA testing as opposed to widespread screening.PMID:34316255 | PMC:PMC8288199 | DOI:10.36141/svdld.v38i2.10971 (Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases)
Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases - July 28, 2021 Category: Respiratory Medicine Authors: Lee M Fidler Sonja Kandel Jolene H Fisher Shikha Mittoo Shane Shapera Source Type: research

RNA expression differences in prostate tumors and tumor-adjacent stroma between Black and White Americans
We examined RNA expression in both tumor and TAS of BA compared to WA. After evaluating the geographical ancestry of each sample, preliminary analysis of our own RNA-seq data of 7 BA and 7 WA TAS revealed 1706 downregulated and 1844 upregulated genes in BA relative to WA PCa patients (p adj
Source: Oncotarget - July 28, 2021 Category: Cancer & Oncology Authors: Farah Rahmatpanah Gabriela De Robles Michael Lilly Thomas Keane Vinay Kumar Dan Mercola Pavneet Randhawa Michael McClelland Source Type: research

The impact of neoadjuvant concurrent chemoradiation on exosomal markers (CD63 and CD9) expression and their prognostic significance in patients with rectal adenocarcinoma
Oncotarget. 2021 Jul 20;12(15):1490-1498. doi: 10.18632/oncotarget.28025. eCollection 2021 Jul 20.ABSTRACTINTRODUCTION: Exosomes have pivotal roles in cancer development. The impact of neoadjuvant concurrent chemoradiation (NCCR) on exosomal markers (CD63 and CD9) expression and their prognostic significance in patients with rectal adenocarcinoma are yet to be explored.MATERIALS AND METHODS: Between 2015 and 2018, 33 patients had rectal adenocarcinoma treated with NCCR and had pre-NCCR biopsy and post-NCCR resected rectum. CD63 and CD9 expression was assessed by immunohistochemistry (IHC). The short-term surrogate endpoint...
Source: Oncotarget - July 28, 2021 Category: Cancer & Oncology Authors: Moh'd Khushman Pranitha Prodduturvar Wadad Mneimneh Valeria Dal Zotto Shalla Akbar Leander Grimm Paul Rider John Hunter Omar Alkharabsheh Girijesh Kumar Patel Jesus C Fabregas Ajay P Singh Source Type: research

Biobank Awareness Changes Opinions of Adolescents and Parents on Participation and Practices
In conclusion, prior awareness of biobanks may facilitate pediatric biobank participation.PMID:34319789 | DOI:10.1089/bio.2020.0157 (Source: Biopreservation and Biobanking)
Source: Biopreservation and Biobanking - July 28, 2021 Category: Biomedical Science Authors: Melissa C Kong James Shih Tamsin E Tarling Cynthia C Kong Heather van Tassel Michelle Dittrick Suzanne M Vercauteren Source Type: research

Calling differentially methylated regions from whole genome bisulphite sequencing with DMRcate
We report DML detection ability with respect to coverage, group methylation difference, sample size, variability and covariate size, both marginally and jointly, and exhaustively with respect to parameter combination. We also benchmark these methods on FDR control and computational time. We use this result to backend and introduce an expanded version of DMRcate: an existing DMR detection tool for microarray data that we have extended to now call DMRs from WGBS data. We compare DMRcate to a set of alternative DMR callers using a similarly realistic simulation strategy. We find DMRcate and RADmeth are the best predictors of ...
Source: Cell Research - July 28, 2021 Category: Cytology Authors: Timothy J Peters Michael J Buckley Yunshun Chen Gordon K Smyth Christopher C Goodnow Susan J Clark Source Type: research

Survival Probabilities and Predictors of Major Depressive Episode Incidence Among Individuals With Various Types of Substance Use Disorders
This study aimed to estimate the survival probabilities related to the occurrence of major depressive episodes (MDEs) after the onset of substance use disorders (SUDs) using data from the 2012-2013 National Epidemiologic Survey on Alcohol and Related Conditions-III.Methods: The Alcohol Use Disorder and Associated Disabilities Interview Schedule-5 was used to diagnose SUD, and psychiatric diagnoses were based on the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition. Individuals with incidents of various SUDs with no prior history of MDEs (n = 5,987 with alcohol use disorder [AUD], 1,353 with cannabis use ...
Source: Journal of Clinical Psychiatry - July 28, 2021 Category: Psychiatry Authors: Ahmed N Hassan Bernard Le Foll Source Type: research

A semi-automated measurement of muscle fiber size using the Imaris software
Am J Physiol Cell Physiol. 2021 Jul 28. doi: 10.1152/ajpcell.00206.2021. Online ahead of print.ABSTRACTThe size and shape of skeletal muscle fibers are affected by various physiological and pathological conditions, such as muscle atrophy, hypertrophy, regeneration, and dystrophies. Hence, muscle fiber cross-sectional area (CSA) is an important determinant of muscle health and plasticity. We adapted the Imaris software to automatically segment muscle fibers based on fluorescent labeling of the plasma membrane, and measure muscle fiber CSA. Analysis of muscle cross sections by the Imaris semi-automated and manual approaches ...
Source: American Journal of Physiology. Cell Physiology - July 28, 2021 Category: Cytology Authors: Jennifer E Gilda Joon-Hyuk Ko Aviv-Yvonne Elfassy Nadav Tropp Anna Parnis Bar Ayalon Wonho Jhe Shenhav Cohen Source Type: research

A semi-automated measurement of muscle fiber size using the Imaris software
Am J Physiol Cell Physiol. 2021 Jul 28. doi: 10.1152/ajpcell.00206.2021. Online ahead of print.ABSTRACTThe size and shape of skeletal muscle fibers are affected by various physiological and pathological conditions, such as muscle atrophy, hypertrophy, regeneration, and dystrophies. Hence, muscle fiber cross-sectional area (CSA) is an important determinant of muscle health and plasticity. We adapted the Imaris software to automatically segment muscle fibers based on fluorescent labeling of the plasma membrane, and measure muscle fiber CSA. Analysis of muscle cross sections by the Imaris semi-automated and manual approaches ...
Source: Am J Physiol Cell Ph... - July 28, 2021 Category: Cytology Authors: Jennifer E Gilda Joon-Hyuk Ko Aviv-Yvonne Elfassy Nadav Tropp Anna Parnis Bar Ayalon Wonho Jhe Shenhav Cohen Source Type: research

Retrospective Analysis of EEG in Patients With COVID-19: EEG Recording in Acute and Follow-up Phases
Clin EEG Neurosci. 2021 Jul 28:15500594211035923. doi: 10.1177/15500594211035923. Online ahead of print.ABSTRACTBackground. Interest in electroencephalographic (EEG) coronavirus disease 2019 (COVID-19) findings has been growing, especially in the search for a specific-features EEG of encephalopathy. Methods. We made a retrospective analysis of 29 EEGs recorded in 15 patients with COVID-19 and neurological symptoms. We classified the EEGs as "Acute EEG" and "follow-up EEG." We did a statistical analysis between voltage and respiratory status of the patient, stay or not in the intensive care unit (ICU), d...
Source: Clinical EEG and Neuroscience - July 28, 2021 Category: Neuroscience Authors: Isabel S áez-Landete Adriana G ómez-Domínguez Beatriz Estrella-Le ón Alba D íaz-Cid Olga Fedirchyk Marta Escribano-Mu ñoz Antonio Pedrera-Mazarro Guillermo Mart ín-Palomeque Guillermo Garcia-Ribas Fernando Rodr íguez-Jorge Gloria Santos-P érez Da Source Type: research

Effects of Host Species Identity and Diet on the Biodiversity of the Microbiota in Puerto Rican Bats
Curr Microbiol. 2021 Jul 27. doi: 10.1007/s00284-021-02607-5. Online ahead of print.ABSTRACTMicrobiota perform vital functions for their mammalian hosts, making them potential drivers of host evolution. Understanding effects of environmental factors and host characteristics on the composition and biodiversity of the microbiota may provide novel insights into the origin and maintenance of these symbiotic relationships. Our goals were to (1) characterize biodiversity of oral and rectal microbiota in bats from Puerto Rico; and (2) determine the effects of geographic location and host characteristics on that biodiversity. We c...
Source: Current Microbiology - July 28, 2021 Category: Microbiology Authors: Steven J Presley Joerg Graf Ahmad F Hassan Anna R Sjodin Michael R Willig Source Type: research

Depression and obesity, but not mild obstructive sleep apnea, are associated factors for female sexual dysfunction
Sleep Breath. 2021 Jul 28. doi: 10.1007/s11325-021-02433-w. Online ahead of print.ABSTRACTPURPOSE: Mild obstructive sleep apnea (OSA) is more prevalent than moderate and severe OSA and is more frequent in men than women. The association between OSA and female sexual dysfunction (FSD) is still poorly explored in published studies. Our aim was to investigate the prevalence of FSD in women with mild OSA and assess the impact of OSA on FSD, as well as to determine the predictors for FSD risk.METHODS: The sample comprised 70 women aged 26-65 years: a control group (N = 28) with no sleep complaints, and a group with mild OSA (an...
Source: Sleep and Breathing - July 28, 2021 Category: Sleep Medicine Authors: Glaury Coelho Lia Bittencourt Monica Levy Andersen Thais Moura Guimar ães Luciana Oliveira E Silva Gabriela Pontes Luz Sergio Tufik Helena Hachul Source Type: research

Veno-arterial extracorporeal membrane oxygenation with concomitant Impella versus concomitant intra-aortic-balloon-pump for cardiogenic shock
Perfusion. 2021 Jul 28:2676591211033947. doi: 10.1177/02676591211033947. Online ahead of print.ABSTRACTINTRODUCTION: The intra-aortic balloon pump (IABP) and Impella are left ventricular unloading devices with peripheral venoarterial extracorporeal membrane oxygenation (VA-ECMO) in place and later serve as bridging therapy when VA-ECMO is terminated. We aimed to determine the potential differences in clinical outcomes and rate of complications between the two combinations of mechanical circulatory support.METHODS: This was a retrospective, single institutional cohort study conducted in the intensive care unit (ICU) of Quee...
Source: Perfusion - July 28, 2021 Category: Cardiovascular & Thoracic Surgery Authors: Shek-Yin Au Ka-Man Fong Chun-Fung Sunny Tsang Ka-Chun Alan Chan Chi Yuen Wong Wing-Yiu George Ng Kang Yin Michael Lee Source Type: research

Nonverbal cognitive assessment of children in Tanzania with and without HIV
Child Neuropsychol. 2021 Jul 27:1-13. doi: 10.1080/09297049.2021.1957809. Online ahead of print.ABSTRACTChildren living with HIV can experience cognitive difficulties. Most neuropsychological tests have been constructed in Western languages, meaning they may not be appropriate for use in non-Western settings. To address this, we used an entirely nonverbal measure of cognitive ability in a sub-Saharan African sample. For this cross-sectional analysis, 316 children (162 HIV+ and 154 HIV-, ages 3-9) completed the Leiter-3 as part of a larger study in Dar es Salaam, Tanzania. Statistical tests included analysis of covariance a...
Source: Child Neuropsychology - July 28, 2021 Category: Child Development Authors: Jonathan Lichtenstein Caitlin Bowers Jennifer Amato Christopher Niemczak Abigail Fellows Albert Magohe Hannah Haile Travis White-Schwoch Nina Kraus Enica Massawe Ndeserua Moshi Jay Buckey Source Type: research

Large-scale reanalysis of refrigerated antemortem blood samples for ethanol content at random intervals
J Forensic Sci. 2021 Jul 27. doi: 10.1111/1556-4029.14796. Online ahead of print.ABSTRACTEthanol stability in antemortem blood stored under various conditions has been widely studied. Most such studies have somewhat limited sample size (
Source: Journal of Forensic Sciences - July 28, 2021 Category: Forensic Medicine Authors: Patrick Allan Kosecki Lori Ann Abbott Melinda Evonne Raines Source Type: research

4D-QSAR models applied to the study of TGF- β1 receptor inhibitors
CONCLUSION: The best QSAR model showed adequate statistical parameters that ensure their fitness, robustness, and predictivity. Structural modifications were assessed, and five new structures were proposed as candidates for a drug for cancer treatment.PMID:34315368 | DOI:10.2174/1568026621666210727161431 (Source: Current Topics in Medicinal Chemistry)
Source: Current Topics in Medicinal Chemistry - July 28, 2021 Category: Chemistry Authors: Tamiris Maria de Assis Teodorico Castro Ramalho Elaine Fontes Ferreira da Cunha Source Type: research

Site selection of straw collection and storage facilities considering carbon emission reduction
This study used cost and carbon emission metrics in a dual-objective planning model to plan the site selection of straw collection and storage facilities. Compared with the current manual calculation in various links in straw supply logistics, modeling can resolve the contradiction between cost and carbon emission considerations and can help meet the goal of Pareto optimum while ensuring supply, reducing costs for enterprises, and providing decision-making assistance for the government. This paper uses transportation theory and a dual-objective, mixed-integer model to study the field of biomass energy. Through the planning...
Source: Environmental Science and Pollution Research International - July 28, 2021 Category: Environmental Health Authors: Jia Mao Qi Sun Changhai Ma Ming Tang Source Type: research

Parvovirus B19 Seroprevalence in Women with Bad Obstetric History in Kirkuk
CONCLUSION: Parvovirus B19 infection may be with bad obstetric outcomes if occurred during pregnancy and OR confirm a significant association of the infection with parvovirus with smoking, occupation, crowding index, education, animal exposure and number of repeated abortion.PMID:34315400 | DOI:10.2174/1871523020666210727142351 (Source: Rural Remote Health)
Source: Rural Remote Health - July 28, 2021 Category: Rural Health Authors: Abdulghani Mohamed Alsamarai Hala Majeed Hassan Mohamed Almoustafa Alsamarai Zainab Khalil Aljumaili Source Type: research

Automated treatment planning of prostate stereotactic body radiotherapy with focal boosting on a fast-rotating O-ring linac: Plan quality comparison with C-arm linacs
CONCLUSIONS: Automated planning of prostate SBRT with focal boosting on the fast-rotating O-ring linac is feasible and achieves similar plan quality as those obtained on clinical C-arm linacs using manual planning.PMID:34318996 | DOI:10.1002/acm2.13345 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - July 28, 2021 Category: Physics Authors: Robin De Roover Wouter Crijns Kenneth Poels Bertrand Dewit C édric Draulans Karin Haustermans Tom Depuydt Source Type: research

Effectiveness of virtual reality-based rehabilitation versus conventional therapy on upper limb motor function of chronic stroke patients: a systematic review and meta-analysis of randomized controlled trials
Conclusions: The upper limb motor function of patients with chronic stroke who underwent VR-based rehabilitative intervention showed significant improvement as compared to the pre-treatment state. Our analysis also revealed no superiority of VR interventions over conservative therapies; however, the difference observed did not accomplish statistical significance.PMID:34315320 | DOI:10.1080/09593985.2021.1941458 (Source: Physiotherapy Theory and Practice)
Source: Physiotherapy Theory and Practice - July 28, 2021 Category: Physiotherapy Authors: Reem M Al-Whaibi Maher S Al-Jadid Hager R ElSerougy Wanees M Badawy Source Type: research

Increased plasma and milk short-chain acylcarnitines concentrations reflect systemic LPS response in mid-lactation dairy cows
Am J Physiol Regul Integr Comp Physiol. 2021 Jul 28. doi: 10.1152/ajpregu.00072.2021. Online ahead of print.ABSTRACTLipopolysaccharides (LPS) challenge the metabolic integrity of high yielding dairy cows, activating the immune system and altering energy metabolism. Fatty acid oxidation, a major energy gaining pathway, can be improved by supplementary carnitine, facilitating the transport of fatty acids into mitochondria. The metabolic response to LPS challenge could alter both the plasma and the milk metabolome. Plasma and milk samples collected from cows treated with (n=27) or without (n=27) dietary carnitine, before and ...
Source: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology - July 28, 2021 Category: Physiology Authors: Wei Xu Sandra Grindler Sven D änicke Jana Frahm Akos Kenez Korinna Huber Source Type: research

Stochastic nitrate simulation under hydraulic conductivity uncertainty of an agricultural basin aquifer at Eastern Thessaly, Greece
This study estimates the effect of hydraulic conductivity uncertainty on the simulation of groundwater nitrate concentration. The proposed framework uses Geostatistical Sequential Gaussian Simulation (SGSIM) for the generation of equally probable realizations of the spatial distribution of hydraulic conductivity. It includes the application of a modelling system based on the following inter-linked models: a rainfall-runoff model, a reservoir operation model, a lake-aquifer interaction model, a groundwater flow model, and a nitrate transport and dispersion model. The last two models simulate the multiple realizations of aqu...
Source: Environmental Science and Pollution Research International - July 28, 2021 Category: Environmental Health Authors: Pantelis Sidiropoulos Nikitas Mylopoulos Lampros Vasiliades Athanasios Loukas Source Type: research

Radiofrequency ablation may improve the beneficial results of vertebroplasty for vertebral hemangiomas: analysis of 46 patients
DISCUSSION: Although minimally invasive percutaneous techniques are indicated as other modalities are ineffective or contraindicated, combining RFA with vertebral augmentation provide prevention of mechanical loading pain, and prevention of somatic pain in patients with spinal hemangiomas.PMID:34315351 | DOI:10.1080/01616412.2021.1956291 (Source: Neurological Research)
Source: Neurological Research - July 28, 2021 Category: Neurology Authors: Ali Serdar Oguzoglu Nilgun Senol Hakan Murat G öksel Source Type: research

A Pre-matriculation Success Program to Improve Pharmacy Students' Academic Performance at a Historically Black University
Conclusion. Findings from this study indicated that implementation of a pre-matriculation success program at a college of pharmacy in a historically Black institution is a viable strategy to improve students' academic success in the first year.PMID:34315700 | DOI:10.5688/ajpe8214 (Source: American Journal of Pharmaceutical Education)
Source: American Journal of Pharmaceutical Education - July 28, 2021 Category: Universities & Medical Training Authors: Mary K Awuonda Emmanuel Akala La'Marcus T Wingate Salome Bwayo Weaver Kirsten Brown Celia Williams-Fowlkes Toyin Tofade Source Type: research