The accuracy and intra- and interobserver variability of PSMA PET/CT for the local staging of primary prostate cancer
ConclusionIn a large, multicentre study evaluating 600 patients with newly diagnosed intermediate and high-risk PCa, we showed that PSMA PET/CT may have a value in local tumour staging when pathological tumour stage in the radical prostatectomy specimen was used as the reference standard. The intra-observer and interobserver variability of assessment of tumour extent on PSMA PET/CT was moderate to substantial. (Source: European Journal of Nuclear Medicine and Molecular Imaging)
Source: European Journal of Nuclear Medicine and Molecular Imaging - April 24, 2024 Category: Nuclear Medicine Source Type: research
Safety and efficacy of multiple-dose versus single-dose MIBG therapy in patients with refractory pheochromocytoma and paraganglioma: a single-center retrospective analysis
ConclusionIn I-131 MIBG therapy for PPGLs, multiple administrations significantly increased only Grade 1 or 2 lymphopenia and leukopenia compared to single administration. (Source: Annals of Nuclear Medicine)
Source: Annals of Nuclear Medicine - April 24, 2024 Category: Nuclear Medicine Source Type: research
Gait differences between COPD and healthy controls: systematic review and meta-analysis
Conclusion
Low-quality evidence shows that people with COPD walk more slowly than healthy controls, which could contribute to an increased falls risk. The evidence for alterations in spatial and temporal components of gait was inconclusive. Gait impairment appears to be an important but understudied area in COPD. (Source: European Respiratory Review)
Source: European Respiratory Review - April 24, 2024 Category: Respiratory Medicine Authors: Buekers, J., Delgado-Ortiz, L., Megaritis, D., Polhemus, A., Breuls, S., Buttery, S. C., Chynkiamis, N., Demeyer, H., Gimeno-Santos, E., Hume, E., Koch, S., Williams, P., Wuyts, M., Hopkinson, N. S., Vogiatzis, I., Troosters, T., Frei, A., Garcia-Aymerich Tags: COPD and smoking Reviews Source Type: research
Effective writing instruction for students in grades 6 to 12: a best evidence meta-analysis
AbstractThe current best evidence meta-analysis reanalyzed the data from a meta-analysis by Graham et al. (J Educ Psychol 115:1004 –1027, 2023). This meta-analysis and the prior one examined if teaching writing improved the writing of students in Grades 6 to 12, examining effects from writing intervention studies employing experimental and quasi-experimental designs (with pretests). In contrast to the prior meta-analysis, we eliminated all N of 1 treatment/control comparisons, studies with an attrition rate over 20%, studies that did not control for teacher effects, and studies that did not contain at least one reliable ...
Source: Reading and Writing - April 24, 2024 Category: Child Development Source Type: research
Effects of mini-basketball training program on social communication impairments and regional homogeneity of brain functions in preschool children with autism spectrum disorder
ConclusionsOur study underscores the effectiveness of a 12-week MBTP in ameliorating SCI and abnormalities in ReHo among preschool children with ASD.Trial registrationThe trial is retrospectively registered on the Chinese Clinical Trial Registry (ChiCTR1900024973; August 5, 2019). (Source: BMC Sports Science, Medicine and Rehabilitation)
Source: BMC Sports Science, Medicine and Rehabilitation - April 24, 2024 Category: Sports Medicine Source Type: research
Molecules, Vol. 29, Pages 1941: Microbiological and Physicochemical Evaluation of Hydroxypropyl Methylcellulose (HPMC) and Propolis Film Coatings for Cheese Preservation
This study aimed to evaluate the efficacy of hydroxypropyl methylcellulose (HPMC) and propolis film as protective coatings for cheese. For this, microbiological analyses were carried out over the cheese’ ripening period, focusing on total mesophilic bacteria, yeasts and moulds, lactic acid bacteria, total coliforms, Escherichia coli, and Enterobacteriaceae. Physicochemical parameters (pH, water activity, colour, phenolic compounds content) were also evaluated. The statistical analysis (conducted using ANOVA and PERMANOVA) showed a significant interaction term between the HPMC film and propolis (factor 1) and ...
Source: Molecules - April 24, 2024 Category: Chemistry Authors: Vanessa B. Paula Lu ís G. Dias Let ícia M. Estevinho Tags: Article Source Type: research
Molecules, Vol. 29, Pages 1942: Splenic Elemental Composition of Breast Cancer-Suffering Rats Supplemented with Pomegranate Seed Oil and Bitter Melon Extract
ka Białek
The aim of this study was to investigate how dietary modifications with pomegranate seed oil (PSO) and bitter melon aqueous extract (BME) affect mineral content in the spleen of rats both under normal physiological conditions and with coexisting mammary tumorigenesis. The diet of Sprague-Dawley female rats was supplemented either with PSO or with BME, or with a combination for 21 weeks. A chemical carcinogen (7,12-dimethylbenz[a]anthracene) was applied intragastrically to induce mammary tumors. In the spleen of rats, the selected elements were determined with a quadrupole mass spectrometer with inductively c...
Source: Molecules - April 24, 2024 Category: Chemistry Authors: Ma łgorzata Białek Tomasz Lepionka Wiktoria Wojtak Anna Ruszczy ńska Ewa Bulska Marian Czauderna Agnieszka Bia łek Tags: Article Source Type: research
The relationship between posttonsillectomy bleeding to hemogram and coagulation parameters
ConclusionsAge, high WBC and neutrophil levels were determined as possible risk factors for PTB. Seasonal and gender distribution, aPTT and INR values were similar in the two groups. In order to prevent and predict bleeding, detailed infection investigation should be performed and the risk of bleeding should be considered to increase with increasing age. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - April 23, 2024 Category: ENT & OMF Source Type: research
The outcomes of growth hormone therapy in the obstructive sleep apnea parameters of Prader –Willi syndrome patients: a systematic review
ConclusionsGrowth hormone therapy is safe for Prader –Willi syndrome patients when analyzing their obstructive sleep apnea parameters. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - April 23, 2024 Category: ENT & OMF Source Type: research
Vestibular function assessment in Idiopathic sudden sensorineural hearing loss: a prospective study
ConclusionVertigo in patients with ISSHL “as objectively confirmed through caloric testing and vHIT” can be considered a sign of severe cochlear damage. Our study demonstrated a significantly increased risk of vestibular affect in patients with ISSHL, especially in the presence of vertigo. Thus, we conclude that the focus in ISSHL shou ld not only be on the cochlea but also on the vestibular system. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - April 23, 2024 Category: ENT & OMF Source Type: research
Voice outcome in medialisation thyroplasty with and without arytenoid adduction: a prospective comparison using intraoperative voice measurements
ConclusionsOur study using intraoperative voice measurements indicate that the addition of arytenoid adduction to medialisation thyroplasty is a benefit in selected patients although more studies are needed due to the many limitations inherent to this field of investigation. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - April 23, 2024 Category: ENT & OMF Source Type: research
The 90% effective dose of intrathecal hyperbaric bupivacaine for Cesarean delivery under combined spinal –epidural anesthesia in parturients with super obesity: an up-down sequential allocation study
ConclusionThe estimated ED90 of hyperbaric bupivacaine with fentanyl and morphine in parturients with super obesity undergoing Cesarean delivery under CSE was approximately 11.5 mg.Study registrationClinicalTrials.gov (NCT03781388); first submitted 18 December 2018. (Source: Canadian Journal of Anesthesia)
Source: Canadian Journal of Anesthesia - April 23, 2024 Category: Anesthesiology Source Type: research
Systematicity of receiving mental health care predicts better subjective well-being of Ukrainians during the second year of the Russian invasion
This study aims to develop and test a multivariable psychosocial prediction model of subjective well-being in Ukrainian adults (n = 1,248) 1.5 years after the 2022 Russian invasion of Ukraine.The research design followed the “Transparent reporting of a multivariable prediction model for individual prognosis or diagnosis” checklist. The online survey combined a questionnaire on sociodemographic characteristics and specifics of living in wartime, as well as validated self-reported inventories: The Modified BBC Subjective Well-being Scale, Acceptance and Action Questionnaire – Version 2 and Connor–Davidson Resilienc...
Source: Mental Health Review Journal - April 23, 2024 Category: Psychiatry Authors: Mariana Velykodna Oksana Tkachenko Oksana Shylo Kateryna Mitchenko Zoia Miroshnyk Natalia Kvitka Olha Charyieva Source Type: research
On the fundamentals of quantum rate theory and the long-range electron transport in respiratory chains
Chem. Soc. Rev., 2024, Advance Article DOI: 10.1039/D3CS00662J, Tutorial ReviewPaulo Roberto Bueno The quantum rate conceptv =E/h =c*/L implies relativistic electrodynamics, permitting the transport of electrons in long-range paths of lengthL and explaining the respiration mechanism if a suitable Boltzmannian statistical setting ofE is applied. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Chemical Society Reviews)
Source: RSC - Chemical Society Reviews - April 23, 2024 Category: Chemistry Authors: Paulo Roberto Bueno Source Type: research
Outdoor air pollution as a risk factor for testing positive for SARS-CoV-2: A nationwide test-negative case-control study in the Netherlands
This study reinforces the need to continue to strive for better air quality to support public health.PMID:38652943 | DOI:10.1016/j.ijheh.2024.114382 (Source: International Journal of Hygiene and Environmental health)
Source: International Journal of Hygiene and Environmental health - April 23, 2024 Category: Environmental Health Authors: Mariana Sim ões Jelle Zorn Lenny Hogerwerf Guus J M Velders L ützen Portengen Miriam Gerlofs-Nijland Marieke Dijkema Maciek Strak Jos é Jacobs Joost Wesseling Wilco J de Vries Suzanne Mijnen-Visser Lidwien A M Smit Roel Vermeulen Lapo Mughini-Gras Source Type: research
