Should You Take Aspirin Every Day? Here ’s What the Science Says
Aspirin is best known as an over-the-counter painkiller. But acetylsalicylic acid, as it’s called chemically, has many other health benefits, as well as side effects, in the body that have only become clear in recent years. Here’s what the latest science says about the health benefits and side effects of aspirin, as well as which conditions it may treat and those it doesn’t appear to improve. (If you are taking aspirin for any reason other than for periodic pain relief, it’s best to consult with your doctor to confirm whether the benefits outweigh the risks in your particular case.) How aspirin affects heart health Aspirin’s second-best known effect is its ability to protect the heart. In people with heart disease who have already had a heart attack, it has been shown to lower the risk of having another. Studies consistently show that people who have had heart attacks or strokes and who take a low-dose aspirin (also known as baby aspirin, which at 81 mg is about a quarter of the dose of regular-strength aspirin) a day can significantly reduce their risk of having another event. Its protective benefits come from aspirin’s ability to lower inflammation, a condition that can attract clot-building factors within blood vessel walls. These can rupture, plugging up tiny vessels in the heart and blocking blood flow. Doctors now believe that taking a daily low-dose aspirin is also a cheap and easy way for people who do not yet have heart disease &m...
Conclusions: Social support was identified as an important variable for older adults with chronic illness who lived alone. Interventions that include social support hold the potential to reduce depression and suicidal ideation in this population.
Conclusions/Implications for Practice: Frailty is a crucial health consideration among older adults. Those who are frail have the highest relative risk of disability, followed by those at risk of frailty. Early assessment of frailty may effectively prevent the occurrence of frailty-induced disability in older adults.
Conclusions: Documentation patterns revealed a lack of proactive and systematic approach to pain assessment and management. Furthermore, there was little documented evidence of efforts to evaluate the effectiveness of pain management interventions. Findings have important implications for standardizing documentation of pain assessment, intervention, and evaluation.
Could a parent-led, home-based physical activity intervention lead to improvements in exercise participation?Medicine and Science in Sports and Exercise
CONCLUSIONS Our study demonstrated that hub DEGs may assist in the molecular understanding of LGG recurrence. These findings still need further molecular studies to identify the assignment of DEGs in LGG. PMID: 31104065 [PubMed - in process]
In this study, we investigated FTH1 mRNA expression and its diagnostic and prognostic value in RCC. MATERIAL AND METHODS The mRNA expression of FTH1 was analyzed using including Oncomine, Gene Expression Omnibus, and Cancer Genome Atlas datasets, while the protein level of FTH1 was analyzed using the Human Protein Atlas database. The associations between FTH1 and clinicopathologic characteristics and survival time and Cox multivariate survival analysis were analyzed using SPSS 22.0 software. A meta-analysis was performed to assess consistency of FTH1 expression. GO, KEGG, and PPI analyses were used to predict biological fu...
AbstractPurposeEndoscopic approach represents a valid alternative to conventional septoplasty. The aim of this study is to analyze the objective and subjective data on 276 patients, who underwent traditional (147) or endoscopic (129) septoplasty.MethodsThis is a prospective observational study on 276 consecutive patients affected by deviated nasal septum (DNS), who underwent isolated septoplasty between 2011 and 2018. 147 of them were treated using an “open” approach, while 129 were treated with an endoscopic approach. The two groups were compared 3 months after surgery: the objective results (complications suc...
Publication date: Available online 19 May 2019Source: Molecular and Cellular EndocrinologyAuthor(s): Tao Tao, Yuying Wang, Bing Xu, Xiuying Mao, Yun Sun, Wei LiuAbstractImpaired steroid production in polycystic ovary syndrome (PCOS) may result from adiponectin system dysfunction. However, adiponectin's role in ovulatory dysfunction remains unclear. We aimed to determine whether human chorionic gonadotropin (hCG) and adiponectin affect progesterone and estradiol secretion by granulosa cells (GCs) from overweight or obese women with PCOS or normal ovulation. ADIPOR2 expression was higher in hCG-treated GCs from PCOS patients...
Adrienne Kennedy of the National Alliance on Mental Health (NAMI) shares the story of losing her son due to type 1 diabetes and mental health issues.
ConclusionART showed therapeutic effects on lupus-prone MRL/lpr mice by inhibiting the differentiation of Tfh cells as well as altering the activation status of Jak2-Stat3 signaling cascade.Graphical Abstract
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