' Cautious' DOAC Underdosing in AF May Push Mortality Higher'Cautious' DOAC Underdosing in AF May Push Mortality Higher
Risk-averse clinicians might be doing more harm than good by prescribing direct oral anticoagulants at lower-than-recommended dosages in hope of avoiding bleeding complications, suggests a study.Medscape Medical News (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - September 18, 2020 Category: Cardiology Tags: Cardiology News Source Type: news

Smoking Ups Your Risk of a Fatal Brain Bleed
Compared to nonsmokers, the risk of fatal bleeding in the brain was three times higher among heavy and moderate smokers, and 2.8 times higher among light smokers. (Source: WebMD Health)
Source: WebMD Health - September 17, 2020 Category: Consumer Health News Source Type: news

Smoking Ups Your Risk of a Fatal Brain Bleed
THURSDAY, Sept. 17, 2020 -- Smokers have a significantly raised risk of dying from a bleeding stroke, a new study warns. For the study, researchers analyzed data from over 16,000 same-sex twin pairs in Finland. The twins were born before 1958 and... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - September 17, 2020 Category: General Medicine Source Type: news

Mosquito Clouds Killing Deer, Cattle In Southwest Louisiana
Swarms of skeeters are biting horses, deer and cattle and leaving them anemic and bleeding under their skins. (Source: Science - The Huffington Post)
Source: Science - The Huffington Post - September 12, 2020 Category: Science Source Type: news

Blood When I Wipe: 11 Causes of Rectal Bleeding
Title: Blood When I Wipe: 11 Causes of Rectal BleedingCategory: Diseases and ConditionsCreated: 9/2/2020 12:00:00 AMLast Editorial Review: 9/2/2020 12:00:00 AM (Source: MedicineNet Hearing General)
Source: MedicineNet Hearing General - September 2, 2020 Category: Audiology Source Type: news

Aspirin Alone Preferred Antithrombotic Strategy After TAVI Aspirin Alone Preferred Antithrombotic Strategy After TAVI
Aspirin alone after TAVI significantly reduced bleeding compared with aspirin plus clopidogrel, without increasing thromboembolic events, in the latest results from the POPular TAVI study.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - August 30, 2020 Category: Consumer Health News Tags: Cardiology News Source Type: news

DR ELLIE CANNON: Bleeding after the menopause must be checked out NOW
DR ELLIE CANNON: Any bleeding after the menopause is not normal, and for this reason it's vital you consult your GP urgently - even if you have seen the blood only once or it's just a small amount. (Source: the Mail online | Health)
Source: the Mail online | Health - August 29, 2020 Category: Consumer Health News Source Type: news

Fewer GI Bleeds With Ticagrelor and Prasugrel After PCI Fewer GI Bleeds With Ticagrelor and Prasugrel After PCI
In a comparison of post-PCI antiplatelet medications, ticagrelor or prasugrel were associated with fewer GI bleeding events than clopidogrel.Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - August 26, 2020 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Implantation Bleeding vs Period
Implantation Bleeding vs. Period (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - August 26, 2020 Category: General Medicine Source Type: news

Sudan May Have Banned FGM, but the Harsh Practice Continues
A performance at a photo show in El Fasher, Sudan, 2018. The new transitional government of Sudan criminalized female genital mutilation this spring, but the practice has not ended. Credit: MOHAMAD ALMAHADY/UNAMIDBy Rhona Scullion, PassBlue*Aug 18 2020 (IPS) Just four months ago, Sudan took the monumental step to ban female genital mutilation, a painful, unnecessary and dangerous procedure that leaves lasting scars. Generally carried out on girls before they reach puberty, genital mutilation is now punishable in Sudan by up to three years in prison and subject to a fine. In a country where 88 percent of women between 15 a...
Source: IPS Inter Press Service - Health - August 18, 2020 Category: International Medicine & Public Health Authors: Rhona Scullion Tags: Africa Crime & Justice Education Gender Gender Violence Headlines Health TerraViva United Nations Source Type: news

CTA effective for detecting arterial bleeding
CT angiography (CTA) is an effective initial imaging exam for determining the...Read more on AuntMinnie.comRelated Reading: Dual-energy CT, CTA reveal COVID-19 lung patterns How helpful is CTA for assessing coronary disease risk? COVID-19 neuro findings marked by mental status, stroke CTA still most common modality for PE diagnosis Use CTA to evaluate obese COVID-19 patients for PE risk (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - August 13, 2020 Category: Radiology Source Type: news

Roche provides update on phase III studies of etrolizumab in people with moderately to severely active ulcerative colitis
Basel, 10 August 2020 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced topline results from its phase III study programme evaluating the investigational medicine etrolizumab in people with moderately to severely active ulcerative colitis. Mixed results were seen in studies evaluating etrolizumab as an induction therapy, and both studies evaluating etrolizumab as a maintenance therapy failed to meet their primary endpoints, showing no significant difference in the proportion of people achieving remission with subcutaneous etrolizumab versus placebo. In the HIBISCUS I induction study, in people without prior anti-tumour ...
Source: Roche Media News - August 10, 2020 Category: Pharmaceuticals Source Type: news

Roche provides update on phase III studies of etrolizumab in people with moderately to severely active ulcerative colitis
Basel, 10 August 2020 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced topline results from its phase III study programme evaluating the investigational medicine etrolizumab in people with moderately to severely active ulcerative colitis. Mixed results were seen in studies evaluating etrolizumab as an induction therapy, and both studies evaluating etrolizumab as a maintenance therapy failed to meet their primary endpoints, showing no significant difference in the proportion of people achieving remission with subcutaneous etrolizumab versus placebo. In the HIBISCUS I induction study, in people without prior anti-tumour ...
Source: Roche Investor Update - August 10, 2020 Category: Pharmaceuticals Source Type: news

Janssen Announces U.S. FDA Approval of SPRAVATO ® (esketamine) CIII Nasal Spray to Treat Depressive Symptoms in Adults with Major Depressive Disorder with Acute Suicidal Ideation or Behavior
TITUSVILLE, N.J. – (August 3, 2020) – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced that the U.S. Food and Drug Administration (FDA) has approved the supplemental new drug application (sNDA) for SPRAVATO® (esketamine) CIII nasal spray, taken with an oral antidepressant, to treat depressive symptoms in adults with major depressive disorder (MDD) with acute suicidal ideation orbehavior.1 SPRAVATO® is the first and only approved medicine that has been shown to reduce depressive symptoms within 24 hours,1 providing a new option for significant symptom relief until a longer-te...
Source: Johnson and Johnson - August 3, 2020 Category: Pharmaceuticals Tags: Innovation Source Type: news

Relationship between gingival bleeding and associated factors with reports of verbal bullying in adolescents - Moraes RB, Knorst JK, Brondani B, Marques BB, Reis MS, Henriqson D, Ardenghi TM.
BACKGROUND: Dentofacial features are related to increased bullying episodes in young people. The aim of this study was to assess the association between gingival bleeding and reports of verbal bullying among adolescents. METHODS: This is a cross-sectio... (Source: SafetyLit)
Source: SafetyLit - July 31, 2020 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

Portable, injectable clotting agent could treat trauma victims on the front lines
(Harvard John A. Paulson School of Engineering and Applied Sciences) In a hospital, internal bleeding can be controlled with the transfusion of clotting agents, such as platelets, but they require careful storage and refrigeration and can't be carried by first responders. Now, researchers report an injectable clotting agent that reduced blood loss by 97 percent in mice models. The freeze-dried agent, which has a physical consistency of cotton candy, can be stored at room temperature for several months and reconstituted in saline before injection. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 31, 2020 Category: International Medicine & Public Health Source Type: news

Tendyne Transcatheter Mitral Valve Shows Sustained Benefits at 2 Years Tendyne Transcatheter Mitral Valve Shows Sustained Benefits at 2 Years
More than 93% of patients had no mitral regurgitation at 2 years, but concerns were raised about rates of major bleeding and disabling stroke.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - July 30, 2020 Category: Consumer Health News Tags: Cardiology News Source Type: news

Featured Review: Interventions available during pandemics for heavy menstrual bleeding: an overview of Cochrane reviews
What is the effectiveness and safety of treatments commonly available during pandemics for heavy menstrual bleeding?Cochrane authors summarised the available evidence on the effectiveness and safety of treatments for heavy menstrual bleeding which can continue during pandemics.  Pandemics impact upon the ability to deliver specialist assessment and treatments. Examples of treatments that commonly continue during pandemics include non-steroidal anti-inflammatory drugs (NSAIDs), antifibrinolytics, combined hormonal contraceptives, and progestogen.Key findingsThere is low-certainty evidence that NSAIDs (mefenamic acid) r...
Source: Cochrane News and Events - July 29, 2020 Category: Information Technology Authors: Katie Abbotts Source Type: news

Smoking Raises Aneurysm Risk for Women
TUESDAY, July 28, 2020 -- Smoking significantly increases a woman's risk of potentially deadly brain aneurysms, a new study warns. An aneurysm is a weakened, bulging section of an artery. If an aneurysm ruptures, it can cause fatal bleeding. The... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - July 28, 2020 Category: General Medicine Source Type: news

A new cell & gene therapy approach to treat common bleeding disorder
(Wake Forest Baptist Medical Center) WFIRM researchers have developed an optimized cellular platform for delivering Factor 8 to better treat patients with hemophilia A. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 28, 2020 Category: International Medicine & Public Health Source Type: news

Long-term outcomes of different loading protocols for implant-supported mandibular overdentures: A systematic review and meta-analysis
ConclusionsImmediate loading protocol or early loading protocolfor mandibular overdentures has been determined to be a well-established treatment and worthy of consideration in clinical practice. (Source: Dental Technology Blog)
Source: Dental Technology Blog - July 28, 2020 Category: Dentistry Source Type: news

Low-Dose Prasugrel Preserves Efficacy but Lowers Bleeding in Elderly Low-Dose Prasugrel Preserves Efficacy but Lowers Bleeding in Elderly
Reduced-dose prasugrel maintained efficacy and was safe in elderly and low-weight patients with acute coronary syndrome in a prespecified ISAR-REACT 5 substudy.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - July 28, 2020 Category: Consumer Health News Tags: Cardiology News Source Type: news

NSAID Use Linked to Cardiovascular, Bleeding Events Post-MI
MONDAY, July 27, 2020 -- For patients with myocardial infarction (MI), nonsteroidal anti-inflammatory drug (NSAID) treatment is associated with a significantly increased risk for cardiovascular and bleeding events, according to a study published in... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - July 27, 2020 Category: Pharmaceuticals Source Type: news

Traumatic bifid tongue: a rare presentation in a child. case report - Kang AS, Kang KS.
INTRODUCTION: Although most tongue lacerations in children can be treated conservatively, accepted indications for suture repair include complex injury, large flaps, and active bleeding. The purpose of this article is to highlight repair of a unique, sever... (Source: SafetyLit)
Source: SafetyLit - July 25, 2020 Category: International Medicine & Public Health Tags: Age: Infants and Children Source Type: news

Anal cancer symptoms: Feeling this sensation could be a warning sign of the deadly disease
ANAL cancer is not as common as other cancers, but one of the main symptoms to note is bleeding from the rectum. Another sign to be aware of is feeling a certain sensation in the anus. (Source: Daily Express - Health)
Source: Daily Express - Health - July 24, 2020 Category: Consumer Health News Source Type: news

New Oral Anticoagulants Drive ACC Consensus on Bleeding New Oral Anticoagulants Drive ACC Consensus on Bleeding
In certain circumstances, patients on oral anticoagulants who experience a bleeding event can discontinue therapy, according to updated guidance from the American College of Cardiology (ACC).Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - July 23, 2020 Category: Consumer Health News Tags: Cardiology News Source Type: news

Phase III data show Roche ’s Port Delivery System with ranibizumab enabled over 98% of patients to go six months between treatments for neovascular age-related macular degeneration
Basel, 22 July 2020 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced detailed results from the phase III Archway study evaluating its investigational Port Delivery System with ranibizumab (PDS) for the treatment of neovascular or “wet” age-related macular degeneration (nAMD), a leading cause of blindness globally.1 In Archway, 98.4% of PDS patients were able to go six months without needing additional treatment and achieved vision outcomes equivalent to patients receiving monthly ranibizumab eye injections, a current standard of care. In the study, PDS was generally well-tolerated, with a favourable benefit...
Source: Roche Media News - July 22, 2020 Category: Pharmaceuticals Source Type: news

Phase III data show Roche ’s Port Delivery System with ranibizumab enabled over 98% of patients to go six months between treatments for neovascular age-related macular degeneration
Basel, 22 July 2020 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced detailed results from the phase III Archway study evaluating its investigational Port Delivery System with ranibizumab (PDS) for the treatment of neovascular or “wet” age-related macular degeneration (nAMD), a leading cause of blindness globally.1 In Archway, 98.4% of PDS patients were able to go six months without needing additional treatment and achieved vision outcomes equivalent to patients receiving monthly ranibizumab eye injections, a current standard of care. In the study, PDS was generally well-tolerated, with a favourable benefit...
Source: Roche Investor Update - July 22, 2020 Category: Pharmaceuticals Source Type: news

Channel Medsystems(R) Receives FDA Approval of its Latest Cerene(R) Cryotherapy Device for the Treatment of Heavy Menstrual Bleeding in the Office Setting
Next-generation technology enhances ease-of-use for physicians and streamlines manufacturability The Company is targeting limited market introduction in Q42020 and commercial launch of the Cerene® Device in the first half of 2021 EMERYVILLE, Cali... Devices, FDA Channel Medsystems, Cerene, Cryotherapy (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - July 21, 2020 Category: Pharmaceuticals Source Type: news

Working toward freeze-drying synthetic platelets
(Case Western Reserve University) A Case Western Reserve University scientist, who has for more than a decade pioneered research into synthetic platelet substitutes, has been awarded a $3.8million grant by the U.S. Department of Defense (DOD) to develop freeze-dried artificial platelets that can treat bleeding in wounded soldiers in the battlefield before they can betaken to a hospital. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - July 21, 2020 Category: Biology Source Type: news

Post-surgical bleeding associated with more deaths when compared to blood clots after surgery
(Vanderbilt University Medical Center) Post-surgical bleeding is associated with more deaths than blood clots from surgery, according to a Vanderbilt University Medical Center study published in the journal Anesthesia& Analgesia. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 21, 2020 Category: International Medicine & Public Health Source Type: news

Ticagrelor-Aspirin Combo: Fewer Repeat Strokes, but More Bleeds Ticagrelor-Aspirin Combo: Fewer Repeat Strokes, but More Bleeds
The combination of ticagrelor and aspirin prevents secondary stroke and cuts mortality, but it also appears to increase the risk for severe bleeding.Medscape Medical News (Source: Medscape Emergency Medicine Headlines)
Source: Medscape Emergency Medicine Headlines - July 20, 2020 Category: Emergency Medicine Tags: Neurology & Neurosurgery News Source Type: news

What Are Some Pediatric Oncological Emergencies?
Discussion Pediatric cancers in the US number about 12,000 per year. After injury, it is the second leading cause of death in children and adolescents. Cancer presentations vary widely, but often begin with non-specific symptoms that continue or progress depending on the location and tumor type. Patients can present with oncological emergencies especially if there are mechanical obstruction such as superior vena cava syndrome or cerebral herniation. More commonly are infections due to immunosuppression. Cancer treatment also causes its own myriad of problems that clinicians need to be aware of to diagnosis and treat, but a...
Source: PediatricEducation.org - July 20, 2020 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

New antiplatelet drug shows promise for treating heart attack
(University of Illinois at Chicago) Researchers have developed a new drug that prevents blood clots without causing an increased risk of bleeding, a common side effect of all antiplatelet medications currently available. A new study describes the drug and its delivery mechanisms and shows that the drug is also an effective treatment for heart attack in animal models. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 15, 2020 Category: International Medicine & Public Health Source Type: news

PCI or Not, Mortality Climbs After Post-ACS Bleeding PCI or Not, Mortality Climbs After Post-ACS Bleeding
Prevention of bleeding after ACS, whether managed medically or with PCI, should get as much attention as prevention of later ischemic events, say researchers, based on their study.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - July 14, 2020 Category: Consumer Health News Tags: Cardiology News Source Type: news

Eltrombopag as bridging therapy to haematopoietic stem cell transplant in severe or very severe aplastic anaemia during the COVID19 pandemic (in adults), NHS England
Aplastic anaemia is a rare and serious bone marrow failure disorder causing a high risk of life-threatening bleeding and infections, and requiring frequent hospital admissions. Current definitive treatments for aplastic anaemia are stem cell transplant or immunosuppressive therapy with antithymocyte globulin and/or ciclosporin. Stem cell transplant is a procedure in which a patient receives healthy stem cells to replace damaged stem cells. Immunosuppressive treatment is where drugs are given to lower the body's immune response. Stem cell transplant and antithymocyte globulin treatment require hospital admission (Source: Cu...
Source: Current Awareness Service for Health (CASH) - July 14, 2020 Category: Consumer Health News Source Type: news

What Causes Early Pregnancy Vaginal Bleeding?
Discussion Pregnancy complications in early pregnancy range from mild to severe. They can include nausea and emesis which often is treated symptomatically, but can cause hyperemesis gravidarum and need hospitalization for intravenous fluids. Mild cramping and slight spotting are not uncommon. Some type of pregnancy bleeding is common with 20-40% of women experiencing it. Women who have early vaginal bleeding have a higher risk of later pregnancy complications. Pregnancy in adolescents is about 10% of all pregnancies. Adolescent pregnancy can be associated with various problems including higher rates of threatened aborti...
Source: PediatricEducation.org - July 13, 2020 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Higher Rates of Pain, Bleeding Found With Essure Birth Control Device
THURSDAY, July 9, 2020 -- The permanent birth control device Essure is associated with higher rates of chronic lower abdominal or pelvic pain and abnormal uterine bleeding compared with tubal ligation, according to interim results of a postmarket... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - July 9, 2020 Category: Pharmaceuticals Source Type: news

How Your Mental Health & Menstrual Cycle Are Linked
Dealing with the physical manifestations of your menstrual cycle can be tough enough. Bleeding, breast tenderness, cramps and bloating can seriously interrupt your daily life. However, your menstrual cycle is also intrinsically linked to your mental health. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - July 9, 2020 Category: Pharmaceuticals Authors: Alice Broster, Contributor Tags: Healthcare /healthcare Innovation /innovation Source Type: news

Essure birth control device tied to higher rates of pain and bleeding, FDA says
Even though it's no longer on the market, new data has emerged around potential side effects of the permanent birth control device Essure. (Source: CNN.com - Health)
Source: CNN.com - Health - July 9, 2020 Category: Consumer Health News Source Type: news

New AI 'smart pill' gut-imaging device takes aim at improved cancer detection
(University of Saskatchewan) A team led by University of Saskatchewan (USask) researcher Khan Wahid has been awarded $250,000 from the federal New Frontiers in Research Fund to create a new pill-sized capsule that uses artificial intelligence (AI)-enabled sensing to diagnose gastrointestinal cancers and bleeding earlier and more precisely than is currently possible. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 8, 2020 Category: International Medicine & Public Health Source Type: news

Mayo Clinic researchers develop a tissue-derived bioactive gel to stop bleeding, aid in vascular healing
PHOENIX, AZ --Researchers at Mayo Clinic are studying the effects of a tissue-derived bioactive gel they developed to improve endovascular embolization - a minimally invasive procedure used to treat bleeding blood vessels and aneurysms. The results of their latest preclinical study are published in the journal Advanced Materials. Endovascular embolization involves a pinhole puncture in [...] (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - July 8, 2020 Category: Research Source Type: news

Failure of a Mexican antivenom on recovery from snakebite-related coagulopathy in French Guiana - Heckmann X, Lambert V, Mion G, Ehrhardt A, Marty C, Perotti F, Carod JF, Jolivet A, Boels D, Lehida Andi I, Larr éché S.
INTRODUCTION: In French Guiana, most snakebites are caused by crotalids, with the main signs being tissue damage and bleeding due to venom-induced coagulopathy. Since December 2014 the Western Guiana Hospital (WGH) has used Antivipmyn TriTM, a Mexican poly... (Source: SafetyLit)
Source: SafetyLit - July 5, 2020 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

Toothpick aspiration induces massive hemoptysis: a case report - Rezaei M, Esfandiari N, Saghebi SR, Pourabdollah M, Tabarsi P.
BACKGROUND: Massive hemoptysis refers to bleeding from the sputum exceeding 100 ml/day. This condition is known to have a poor prognosis. Although foreign body aspiration is not as common as other risk factors, it may result in massive hemoptysis. In the c... (Source: SafetyLit)
Source: SafetyLit - July 4, 2020 Category: International Medicine & Public Health Tags: Drowning, Suffocation Source Type: news

Featured Review: Induction of labour at or beyond 37 weeks ’ gestation
A normal pregnancy lasts about 40 weeks (the gestation period) from the start of the woman's last menstrual period. If a pregnancy lasts too long, a woman and her clinician may wish to stimulate the woman ’s body to begin labour. This is called induction.Babies may be at a greater risk of death, before or shortly after birth, after prolonged gestation. However, induction of labour may also have risks for mothers and their babies, especially if women are not ready to labour.Current tests cannot predict whether babies would be better to stay inside their mother or whether labour should be induced to make the birth happ...
Source: Cochrane News and Events - July 2, 2020 Category: Information Technology Authors: Lydia Parsonson Source Type: news

Treating periodontitis-a systematic review and meta-analysis comparing ultrasonic and manual subgingival scaling at different probing pocket depths
ConclusionWhen initial PPD was 4-6  mm, PPD reduction proved manual subgingival scaling was superior, but CAL results showed no statistical differences between the two means. When initial PPD was ≥6 mm, PPD and CAL reductions suggested that manual subgingival scaling was superior. (Source: Dental Technology Blog)
Source: Dental Technology Blog - July 1, 2020 Category: Dentistry Source Type: news

Bleeding to death in a big city: an analysis of all trauma deaths from hemorrhage in a metropolitan area over one year - Kalkwarf KJ, Drake SA, Yang Y, Thetford C, Myers L, Brock M, Wolf DA, Persse D, Wade CE, Holcomb JB.
BACKGROUND: Hemorrhage is the most common cause of potentially-preventable trauma deaths, but no studies have focused on all civilian traumatic deaths from hemorrhage so we describe a year of these deaths from a large county to identify opportunities for p... (Source: SafetyLit)
Source: SafetyLit - June 30, 2020 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

Direct-acting oral anticoagulants (DOACs): reminder of bleeding risk, including availability of reversal agents, MHRA (drug safety update 29th June 2020)
Remain vigilant for signs and symptoms of bleeding complications during treatment with DOACs (apixaban, dabigatran, edoxaban, rivaroxaban), especially in patients with increased bleeding risks. Specific reversal agents are available for dabigatran (Praxbind ▼, idarucizumab), and apixaban and rivaroxaban (Ondexxya▼, andexanet alfa). (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - June 29, 2020 Category: Consumer Health News Source Type: news

Roche announces new data at the ISTH 2020 Congress, demonstrating ongoing commitment to advancing care for people with haemophilia A
Basel, 29 June 2020 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced that new data from its haemophilia A clinical programme will be presented at the International Society on Thrombosis and Haemostasis (ISTH) 2020 Congress on 12-14 July 2020. Data will include updated safety results from the phase IIIb STASEY study of Hemlibra ® (emicizumab) and new results from the phase III HAVEN 5 study of Hemlibra. Data will also include insights into the impact of living with haemophilia A. Spark Therapeutics (a member of the Roche Group) will also present data from the initial dose cohorts of its phase I/II SPK-8011 gene ther...
Source: Roche Media News - June 29, 2020 Category: Pharmaceuticals Source Type: news

Incidence of VTE, Major Bleeding High in Primary CNS Lymphoma
MONDAY, June 29, 2020 -- The incidence of venous thromboembolism (VTE) and major bleeding is high among patients with primary central nervous system lymphoma (PCNSL), according to a study published online June 23 in Leukemia& Lymphoma. Anjlee... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - June 29, 2020 Category: Pharmaceuticals Source Type: news