What are Potential Health Problems Associated with Polycystic Ovary Syndrome?
DiscussionPolycystic ovary syndrome (PCOS) affects 6-8% of reproductive-age women making it the most common endocrinopathy in this age group. There is no consensus on the specific diagnostic criteria for PCOS in adolescents as many of the characteristics overlap with normal adolescent physiology. However, patients should have evidence of hyperandrogenism, oligo- or amenorrhea, and potentially polycystic ovaries. PCOS has a genetic component although a specific gene has not been identified. Incidence of PCOS is 20-40% for a woman with a family history. Hyperandrogenism Androgen levels change during puberty therefore actual measurement and interpretation can make the diagnosis more difficult. Obesity increases androgens. Puberty is associated with a 25-50% decrease in insulin sensitivity. Therefore evidence of hyperandrogenism can be difficult to document. Acne and hirsutism are common presentations. Hirsutism is the presence of terminal hairs in androgen dependent areas (i.e.male pattern) and is evidence of hyperandrogenism. Hypertrichosis is increase in vellus hair in non-male patterned areas such as forearms and lower legs and needs to be distinguished from hirsutism. Hypertrichosis is not evidence of hyperandrogenism. Patients may also have an increase in muscle mass or voice deepening. Oligo- or amenorrhea Anovulatory cycles are normal in pubertal girls so oligomenorrhea ( 2 years or have amenorrhea past the normal menarche should be considered for evaluation. This is ...
CONCLUSION: More than 50% of respondents expressed some degree of depressive and anxiety symptoms (68.5% and 54.4%, respectively). Approximately 9% of respondents exhibited moderately severe to severe depressive symptoms; 5.8% exhibited severe anxiety symptoms. Respondents reporting regular exercise, higher self-confidence, and better satisfaction with both friendship and academic performance had fewer depressive and anxiety symptoms. PMID: 30245480 [PubMed - as supplied by publisher]
Arya Greenlee, three, from Missouri, died in March 2018 from undiagnosed type 1 diabetes. Normal blood sugar levels are less than 100 mg/dL but Arya's were 500 mg/dL at the time of her death.
(Reuters Health) - Most men shouldn't get routine prostate cancer screening because the potential benefits are small and there are clear harms, an international panel of experts concludes.
A couple weeks back, I met with MIRA Fertility Tracker at TechCrunch Disrupt 2018. Sylvia Kang, CEO &Co-founder of MIRA, spoke to me about her new fertility tester for women trying to track their cycles. It also has an AI component built into its system, in order to inform women the days they are most likely to get pregnant. MIRA also took center stage at #Health2con’s Venture Connect, placing 1st among a series of talented health tech startups- Matthew Holt
CONCLUSION: The present study suggests that TNF-α, IFN-γ, and IL-10 gene variants may not be associated with the development of RHD in South Indian population. PMID: 30247944 [PubMed - as supplied by publisher]
Authors: Oksuzoglu A, Engin Ustun Y, Aktulay A, Yoruk O, Seckin B, Danisman N Abstract BACKGROUND: Our aim is to investigate whether the maternal serum levels of first and second trimester serum analytes are altered in women with epilepsy in pregnancy. METHODS: Maternal serum biochemical markers (estriol, alpha-fetoprotein [AFP], human chorionic gonadotrophin [hCG], free β hCG, pregnancy-associated plasma protein-A) were compared in a series of 122 pregnant women with epilepsy and in a cohort of 122 normal pregnant women. The serum samples were obtained between 11-13 6/7 weeks and 16-18 weeks gestation. ...
Conclusions: We demonstrated that LCC was associated with better prognosis, especially for patients with distant metastasis. Future trails should seek to identify the underlying mechanism. PMID: 30245712 [PubMed]
Authors: Błaszczyk E, Lorek M, Francuz T, Gieburowska J, Gawlik A Abstract Background: Turner syndrome (TS) predisposes an individual to obesity and related metabolic disorders. As the TS population is at a higher risk of cardiovascular diseases and malformations, research into laboratory markers of metabolic complications has been ongoing. Special significance has recently been attributed to matrix metalloproteinases (MMPs), their inhibitors (TIMPs), and neurotrophic factors, such as BDNF and GDNF. Objective: To establish whether cardiometabolic risk in patients with TS is reflected in the concentrations of m...
The objective of this study is to observe if mild hyperuricemia and a high-fructose diet influence the cardiovascular and metabolic systems in hypogonadic female Wistar rats compared to normogonadic female rats. Methods: Fifty-six (56) adult female Wistar rats were used in the present work. Animals were divided into two groups: normogonadic (NGN) and hypogonadic (HGN). These groups were also divided into four subgroups in accordance with the treatment: control with only water (C), fructose (F), oxonic acid (OA), and fructose + oxonic acid (FOA). Lipid profile, glycemia, uric acid, and creatinine determina...
BREAST cancer symptoms are important to know for it ’s the most common type of cancer in the UK. While you should be able to recognise the initial signs, you should also be aware other symptoms can develop when the disease has advanced.
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