Janssen to Highlight Depth of Solid Tumor Portfolio at ASCO GU
RARITAN, N.J., February 3, 2020 – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today multiple data presentations from a robust solid tumor portfolio that will be featured at the American Society of Clinical Oncology Genitourinary (ASCO GU) Cancers Symposium, taking place February 13-15 in San Francisco. Company-sponsored data presentations will include clinical results for ERLEADA® (apalutamide) and niraparib in prostate cancer; and BALVERSA™ (erdafitinib) in bladder cancer. “We are committed to improving outcomes in patients with prostate and bladder cancer where high unmet...
Source: Johnson and Johnson - February 3, 2020 Category: Pharmaceuticals Tags: Innovation Source Type: news

What Do You Do For Breast Milk Jaundice?
Discussion Almost all infants in the first few days of life have some elevation of their bilirubin because of the various physiologic changes they undergo in the transition to extra-uterine life. This is a common problem managed by many different inpatient and outpatient healthcare providers. This hyperbilirubinemia is usually unconjugated and resolves in the first 1-2 weeks of life. However, when it does not resolve, health care providers have 3 general paths to follow when considering a cause: inadequate breast milk intake, an underlying organic cause or breast milk jaundice. Inadequate breastfeeding is not uncommon and...
Source: PediatricEducation.org - February 3, 2020 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

One Brave Mom-Entrepreneur Sets Out To Solve The Thyroid Care Crisis
January is #ThyroidAwarenessMonth and this mom-entrepeneur and cofounder of Paloma Health is helping to raise awareness and innovate care for hypothyroidism. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - February 1, 2020 Category: Pharmaceuticals Authors: Anuja Khemka, Contributor Source Type: news

Brown Adipose Tissue Response to Cold in Hypothyroidism Brown Adipose Tissue Response to Cold in Hypothyroidism
New research finds that girls with autoimmune hypothyroidism show reduced brown adipose tissue activation in response to cold stimulation.Journal of the Endocrine Society (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 20, 2020 Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news

Older woman presenting with recurrent falls: an unusual manifestation of hypothyroidism - Kwon KY, Lee M, Ju H, Im K.
No abstract is available for this article. Language: en... (Source: SafetyLit)
Source: SafetyLit - January 11, 2020 Category: International Medicine & Public Health Tags: Age: Elder Adults Source Type: news

Subclinical hypothyroidism linked to reduced ovarian reserve
According to a study published inThyroid, subclinical hypothyroidism may reduce ovarian reserve in women over 35 years old. Healio (Source: Society for Endocrinology)
Source: Society for Endocrinology - January 10, 2020 Category: Endocrinology Source Type: news

Once-Weekly Thyroxine for Thyroxine-Resistant Hypothyroidism Once-Weekly Thyroxine for Thyroxine-Resistant Hypothyroidism
Once-weekly thyroxine treatment may be a safe and effective option for patients with hypothyroidism, particularly those with thyroxine resistance or poor adherence to standard daily therapy.Journal of the Endocrine Society (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 6, 2020 Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news

Overt Hypothyroidism May Up All-Cause Mortality in the Elderly
MONDAY, Dec. 23, 2019 -- Hypothyroidism is significantly associated with increased all-cause mortality, but not cardiovascular mortality, among the elderly, according to a review published online Dec. 12 in the Journal of Clinical Endocrinology... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - December 23, 2019 Category: Pharmaceuticals Source Type: news

Jury Still Out on Whether to Treat Subclincal Hypothyroidism in Elderly Jury Still Out on Whether to Treat Subclincal Hypothyroidism in Elderly
A new systematic review suggests elderly patients with overt hypothyroidism should receive levothyroxine treatment, but for those with subclinical hypothyroidism, the advice is less certain.Medscape Medical News (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - December 13, 2019 Category: Cardiology Tags: Diabetes & Endocrinology News Source Type: news

Jury Still Out on Whether to Treat Subclinical Hypothyroidism in Elderly Jury Still Out on Whether to Treat Subclinical Hypothyroidism in Elderly
A new systematic review suggests elderly patients with overt hypothyroidism should receive levothyroxine treatment, but for those with subclinical hypothyroidism, the advice is less certain.Medscape Medical News (Source: Medscape Diabetes Headlines)
Source: Medscape Diabetes Headlines - December 13, 2019 Category: Endocrinology Tags: Diabetes & Endocrinology News Source Type: news

Hypothyroidism may increase risk of death in older adults
According to a study published in theJournal of Clinical and Endocrinology Metabolism, adults over the age of 60 with hypothyroidism may have an increased risk of death.News Medical (Source: Society for Endocrinology)
Source: Society for Endocrinology - December 13, 2019 Category: Endocrinology Source Type: news

PhD Studentship in thyroid hormones
Oxford Brookes University are offering a PhD Studentship in the role of thyroid hormones during fetal growth and development.The aim of this PhD studentship is to investigate the mechanisms by which hypothyroidism in utero influences the activity of the fetal HPA axis.  In collaboration with colleagues at the Universities of Oxford and Cambridge, the project will use immunohistochemistry to assess neuronal networks and pituitary cell populations, and tissue culture to examine the secretory capacity of the fetal pituitary in vitro.For further information contact Dr Alison Forhead:aforhead@brookes.ac.ukEligibility: ...
Source: Society for Endocrinology - November 28, 2019 Category: Endocrinology Source Type: news

Questions Remain Over Thyroid Management in Pregnancy Questions Remain Over Thyroid Management in Pregnancy
Although 1 in 200 women with fertility issues have overt thyroid dysfunction and many more subclinical hypothyroidism, it is unclear how best to identify or manage them, say UK researchers.Medscape News UK (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 18, 2019 Category: Consumer Health News Tags: Ob/Gyn & Women ' s Health News Source Type: news

What is the Lifespan for a Child with Holoprosencephaly?
Discussion Holoprosencephaly (HPE) is a clefting problem of the brain. “[HPE] the result of incomplete or absent midline division of the embryonic forebrain into distinct cerebral hemispheres (prosencephalon) between the 18th and 28th day after conception.” There are four distinct subtypes: Alobar – both hemispheres are completely fused and are not separated into the left and right hemispheres. There is agenesis of the corpus callosum, arrhinencephaly and a single ventricle with fused thalami. Facial features are almost always affected. Semilobar – the cerebral hemispheres are fused anteriorly bu...
Source: PediatricEducation.org - November 18, 2019 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

GP Alerts Could Improve Hypothyroidism Management GP Alerts Could Improve Hypothyroidism Management
A simple system of alerts that leverages existing clinical tools could significantly improve hypothyroidism management in primary care, although'alert fatigue'may be an issue, say UK researchers.Medscape News UK (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 12, 2019 Category: Consumer Health News Tags: Family Medicine/Primary Care News Source Type: news

Variations in the Care of Hypothyroidism During Pregnancy Variations in the Care of Hypothyroidism During Pregnancy
A national survey of physicians provides insight into the variation in clinical practices regarding the management of pregnant women with subclinical hypothyroidism.Journal of the Endocrine Society (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 12, 2019 Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news

Hypothyroidism Over-Treatment Linked to Risk of Atrial Fibrillation Hypothyroidism Over-Treatment Linked to Risk of Atrial Fibrillation
Patients with thyroid hormone levels suggesting over-treatment for hypothyroidism had an increased likelihood of atrial fibrillation and stroke, independent of other risk factors.Medscape Medical News (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - November 6, 2019 Category: Cardiology Tags: Diabetes & Endocrinology News Source Type: news

Elderly people with hypothyroidism have increased mortality risk
Overt hypothyroidism in individuals ages 60 years or more increases mortality risk, according to findings presented at the annual meeting of the American Thyroid Association.Healio (Source: Society for Endocrinology)
Source: Society for Endocrinology - November 4, 2019 Category: Endocrinology Source Type: news

Mifepristone Increases TH Requirements in Hypothyroidism Mifepristone Increases TH Requirements in Hypothyroidism
Treatment with mifepristone resulted in increased levothyroxine requirements among patients with Cushing disease and central hypothyroidism.Journal of the Endocrine Society (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 14, 2019 Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news

Thyroid hormone replacement therapy safe for pregnant women
Hormone replacement therapy for hypothyroidism taken during pregnancy does not increase risk for language impairments in children, according to a study published inJAMA Network Open.MedPageToday (Source: Society for Endocrinology)
Source: Society for Endocrinology - October 4, 2019 Category: Endocrinology Source Type: news

Subclinical Hypothyroidism Balancing Act: Knowing When to Treat Subclinical Hypothyroidism Balancing Act: Knowing When to Treat
Dr Tyler Drake presents three cases and discusses the factors to consider when deciding whether or not to treat subclinical hypothyroidism.American Thyroid Association (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 3, 2019 Category: Consumer Health News Tags: Diabetes & Endocrinology Case Challenge Source Type: news

Recommended TSH Norm for Patients on Thyroxine Shows No Ill Effect Recommended TSH Norm for Patients on Thyroxine Shows No Ill Effect
Recommended"normal" thyroid-stimulating hormone (TSH) concentrations for hypothyroid patients receiving thyroxine are not associated with increased risk of cardiovascular disease, fractures, or all-cause mortality, according to new findings.Reuters Health Information (Source: Medscape Orthopaedics Headlines)
Source: Medscape Orthopaedics Headlines - September 19, 2019 Category: Orthopaedics Tags: Diabetes & Endocrinology News Source Type: news

Medical News Today: Hyperthyroidism: Foods to eat and avoid
This article looks at which foods and nutrients to eat and which to avoid for an overactive thyroid. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - September 6, 2019 Category: Consumer Health News Tags: Hypothyroid Source Type: news

Natural remedies for hypothyroidism
(Natural News) Hypothyroidism is a condition wherein the thyroid glands do not produce enough hormones to sustain metabolic functions. As a result, people with this condition may experience a wide array of symptoms like fatigue, constipation, aches and pains, and depression. While this disease can affect both sexes, it is especially common in women and... (Source: NaturalNews.com)
Source: NaturalNews.com - September 2, 2019 Category: Consumer Health News Source Type: news

Hypothyroidism Manifesting As Multiple Cranial Neuropathies Hypothyroidism Manifesting As Multiple Cranial Neuropathies
This case highlights the need for considering hypothyroidism in the differential diagnosis of new neurological deficits.Journal of Medical Case Reports (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - August 21, 2019 Category: Consumer Health News Tags: Family Medicine/Primary Care Journal Article Source Type: news

What Does the General Pediatrician Do When There Are Concerns for a Rare Disease?
Discussion Bardet-Biedl syndrome (BBS) is a rare disorder. It is usually considered an autosomal recessive disorder but there is significant intra-familial variability. There are multiple genes (~20 currently) involved and it is believed that the phenotypic variability is due to “…differences in the total mutational load across different BBS associated genes….” It is a ciliopathy where mutation changes in proteins in the cilias causes problems in the cilia’s functioning particularly signaling. Cilia are important in signaling to maintain tissue and cellular homeostasis. Obviously screening o...
Source: PediatricEducation.org - August 19, 2019 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Association of Oral Lichen Planus and Thyroid Gland Diseases Association of Oral Lichen Planus and Thyroid Gland Diseases
This study investigated a possible link between these two immune-related conditions.BMC Oral Health (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - August 15, 2019 Category: Consumer Health News Tags: Dental & Oral Health Journal Article Source Type: news

TSH levels for diagnosis of congenital hypothyroidism
Age-adjusted reference ranges of thyroid-stimulating hormone are needed to reliably diagnose congenital hypothyroidism in preterm babies, according to a study published inPediatrics.Endocrinology Advisor (Source: Society for Endocrinology)
Source: Society for Endocrinology - August 1, 2019 Category: Endocrinology Source Type: news

Miracle pill denied to patients in postcode lottery that's diving doctors
The patients have hypothyroidism, where your thyroid gland doesn't produce enough of the hormones which are key to maintaining energy. (Source: the Mail online | Health)
Source: the Mail online | Health - July 16, 2019 Category: Consumer Health News Source Type: news

Similar CV Event Rates Seen for Generic, Brand Levothyroxine
THURSDAY, June 27, 2019 -- Cardiovascular event rates are similar for patients with newly treated hypothyroidism receiving generic and brand levothyroxine (L-T4), according to a study published online April 26 in the Mayo Clinic Proceedings. Robert... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - June 27, 2019 Category: Pharmaceuticals Source Type: news

Study finds similar cardiovascular outcomes for generic, brand-name drugs for hypothyroidism
(Mayo Clinic) A new study by Mayo Clinic researchers may have broad implications for treatment of patients with predominantly benign thyroid disease and newly treated hypothyroidism. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 19, 2019 Category: International Medicine & Public Health Source Type: news

Study finds similar cardiovascular outcomes for generic, brand-name drugs for hypothyroidism
JACKSONVILLE, Fla. -- A new study by Mayo Clinic researchers may have broad implications for treatment of patients with predominantly benign thyroid disease and newly treated hypothyroidism. The study, to be published in Mayo Clinic Proceedings in July, looked at whether generic and brand-name levothyroxine therapy affected hospitalization for cardiovascular events for those patients who [...] (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - June 19, 2019 Category: Databases & Libraries Source Type: news

Medical News Today: Through my eyes: Autoimmune conditions
My name is Amy Hoey, and I have several autoimmune conditions. This is the story of my long and frustrating journey pursuing diagnoses. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - June 12, 2019 Category: Consumer Health News Tags: Hypothyroid Source Type: news

Experts challenge new subclinical hypothyroidism guidelines
The Society for Endocrinology and the British Thyroid Association have issued a statement challenging a recent guideline published in the BMJ, which concludes that most adults do not require treatment for the condition.Healio (Source: Society for Endocrinology)
Source: Society for Endocrinology - May 31, 2019 Category: Endocrinology Source Type: news

Society for Endocrinology & British Thyroid Association issue statement against new treatment recommendation
(Society for Endocrinology) The Society for Endocrinology (SfE) and British Thyroid Association (BTA) have issued a statement challenging recommendations made in a clinical practice guideline on managing subclinical hypothyroidism (SCH), published recently in the BMJ. Both SfE and BTA disagree with the conclusion that most adults with SCH do not require treatment, as the guideline does not provide sufficient evidence, especially in younger individuals, to support this claim. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 29, 2019 Category: International Medicine & Public Health Source Type: news

Why doctors now warn against routinely treating mild thyroid issues
Giving daily levothyroxine pills to people with a mild abnormality called subclinical hypothyroidism offers no benefit, a review of 21 clinical trials suggests. (Source: CBC | Health)
Source: CBC | Health - May 17, 2019 Category: Consumer Health News Tags: News/Health Source Type: news

Mild Hypothyroidism Being Overtreated, Avoid Pills
, Says Panel (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - May 17, 2019 Category: General Medicine Source Type: news

Mild Hypothyroidism Being Overtreated, Avoid Pills, Says Panel Mild Hypothyroidism Being Overtreated, Avoid Pills, Says Panel
In a"strong recommendation," an international panel of experts advise that patients with subclinical hypothyroidism should not be routinely prescribed levothyroxine; evidence shows few benefits.Medscape Medical News (Source: Medscape Diabetes Headlines)
Source: Medscape Diabetes Headlines - May 16, 2019 Category: Endocrinology Tags: Diabetes & Endocrinology News Source Type: news

Thyroid treatment is being over-prescribed in the UK
Research published in theBMJsuggests that lifelong treatment for hypothyroidism is not always necessary or beneficial for patients with mild cases.BBC (Source: Society for Endocrinology)
Source: Society for Endocrinology - May 16, 2019 Category: Endocrinology Source Type: news

Thyroid Hormones Not Endorsed for Subclinical Hypothyroidism
Almost all adults with SCH would not benefit from treatment with thyroid hormones (Source: The Doctors Lounge - Psychiatry)
Source: The Doctors Lounge - Psychiatry - May 15, 2019 Category: Psychiatry Tags: Cardiology, Endocrinology, Family Medicine, Gynecology, Internal Medicine, Neurology, Nursing, Pharmacy, Psychiatry, Journal, Source Type: news

Thyroid Hormones Not Endorsed for Subclinical Hypothyroidism
WEDNESDAY, May 15, 2019 -- Thyroid hormones are not recommended for adults with subclinical hypothyroidism (SCH), according to an article published online May 14 in The BMJ. Geertruida E. Bekkering, Ph.D., from KU Leuven in Belgium, and colleagues... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - May 15, 2019 Category: Pharmaceuticals Source Type: news

‘Avoid’ hormone treatment in adults with mild thyroid problems
Thyroid hormones should not be routinely offered to adults with a mildly underactive thyroid gland – known as subclinical hypothyroidism – a panel of international experts has warned. (Source: Nursing Times)
Source: Nursing Times - May 15, 2019 Category: Nursing Source Type: news

ASK THE GP: Dr Martin Scurr answers your health questions 
Here, the Daily Mail's resident GP answers your health concerns in his weekly column. Today, he looks at a hypothyroid crisis, which can be fatal. (Source: the Mail online | Health)
Source: the Mail online | Health - May 14, 2019 Category: Consumer Health News Source Type: news

Medical News Today: 5 causes of cold intolerance
While some people simply get colder more easily than others, cold intolerance can also result from an underlying medical condition. In this article, learn about possible causes of feeling cold all the time, including hypothyroidism, anemia, and Raynaud ’s disease. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - May 10, 2019 Category: Consumer Health News Tags: Cardiovascular / Cardiology Source Type: news

Does Hypothyroidism Impact Risk of Breast Cancer Recurrence or Death?
Researchers evaluated whether breast cancer patients with hypothyroidism at diagnosis or who develop it later have an increased risk of recurrence or death. (Source: CancerNetwork)
Source: CancerNetwork - May 8, 2019 Category: Cancer & Oncology Authors: Christina Bennett, MS Source Type: news

A selenium/myo-inositol combination can naturally heal Hashimoto’s disease
(Natural News) Hashimoto’s disease is one of the most common causes of hypothyroidism in the U.S., affecting at least one out of 20 people. A recent study, however, showed that the combination of selenium and myoinositol can work wonders with people who have this autoimmune condition. The study, which appeared in the journal European Review for Medical... (Source: NaturalNews.com)
Source: NaturalNews.com - May 6, 2019 Category: Consumer Health News Source Type: news

Hypothyroidism Limits Adaptation to Cold Environments Hypothyroidism Limits Adaptation to Cold Environments
Therapy seems to relieve the symptoms, and patients with hypothyroidism show significant increases in energy expenditure after being treated to normalize hormone levels.Medscape Medical News (Source: Medscape Diabetes Headlines)
Source: Medscape Diabetes Headlines - April 25, 2019 Category: Endocrinology Tags: Diabetes & Endocrinology News Source Type: news

Mona Lisa may have had hypothyroidism
In a recent opinion article, published in Hormones-International Journal of Endocrinology and Metabolism, an endocrinologist theorises that Mona Lisa may have suffered from severe hypothyroidism.Medical Xpress (Source: Society for Endocrinology)
Source: Society for Endocrinology - April 18, 2019 Category: Endocrinology Source Type: news

Pediatric endocrinologist gives iconic 'Mona Lisa' a second medical opinion
(University of Texas Health Science Center at Houston) Michael Yafi, MD, refutes the most recent hypothesis that 'Lisa' had hypothyroidism and psychomotor retardation. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 17, 2019 Category: International Medicine & Public Health Source Type: news