More Data Tie Obesity to Occult Endometrial Cancer
(MedPage Today) -- Bariatric surgery appeared to normalize neoplastic endometrium in some women (Source: MedPage Today Endocrinology)
Source: MedPage Today Endocrinology - November 1, 2018 Category: Endocrinology Source Type: news

New study takes first step toward treating endometriosis
(Northwestern University) Researchers at Northwestern Medicine have taken the first step in bioengineering the human uterus to treat endometriosis, uterine-factor infertility and endometrial cancer. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - November 1, 2018 Category: Cancer & Oncology Source Type: news

COUNTERPOINT: Should Radiation Therapy Be Routinely Used in the Adjuvant Treatment of Stage III Endometrial Cancer?
The routine use of adjuvant radiation therapy in stage III endometrial cancer patients is not supported by the current literature and should not be employed universally in this group of patients. (Source: CancerNetwork)
Source: CancerNetwork - September 19, 2018 Category: Cancer & Oncology Authors: John P. Diaz, MD, FACOG Source Type: news

POINT: Should Radiation Therapy Be Routinely Used in the Adjuvant Treatment of Stage III Endometrial Cancer?
Adjuvant radiation therapy provides a local control benefit in stage III endometrial carcinoma patients, as strongly suggested in retrospective and prospective series. (Source: CancerNetwork)
Source: CancerNetwork - September 18, 2018 Category: Cancer & Oncology Authors: Mark E. Bernard, MD, Marcus E. Randall, MD Source Type: news

Minimal functional driver gene heterogeneity among untreated metastases
Metastases are responsible for the majority of cancer-related deaths. Although genomic heterogeneity within primary tumors is associated with relapse, heterogeneity among treatment-naïve metastases has not been comprehensively assessed. We analyzed sequencing data for 76 untreated metastases from 20 patients and inferred cancer phylogenies for breast, colorectal, endometrial, gastric, lung, melanoma, pancreatic, and prostate cancers. We found that within individual patients, a large majority of driver gene mutations are common to all metastases. Further analysis revealed that the driver gene mutations that were not share...
Source: ScienceNOW - September 6, 2018 Category: Science Authors: Reiter, J. G., Makohon-Moore, A. P., Gerold, J. M., Heyde, A., Attiyeh, M. A., Kohutek, Z. A., Tokheim, C. J., Brown, A., DeBlasio, R. M., Niyazov, J., Zucker, A., Karchin, R., Kinzler, K. W., Iacobuzio-Donahue, C. A., Vogelstein, B., Nowak, M. A. Tags: Medicine, Diseases reports Source Type: news

Catheter-based intervention drains endometrial cysts
South Korean researchers found that by replacing an interventional needle with...Read more on AuntMinnie.comRelated Reading: USPSTF again nixes screening for ovarian cancer Women with endometriosis have higher heart disease risk Ultrasound should be 1st choice for female pelvic imaging The Practice of Ultrasound: Part 4 -- Female pelvic ultrasound Rigorous investigation using MRI can prove crucial for endometriosis (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - August 31, 2018 Category: Radiology Source Type: news

Postmenopausal Bleeding Common in Women With Endometrial Cancer
A meta-analysis finds that postmenopausal bleeding occurs in approximately 90% of women with endometrial cancer. (Source: CancerNetwork)
Source: CancerNetwork - August 30, 2018 Category: Cancer & Oncology Authors: Leah Lawrence Source Type: news

Oral Contraceptive Use and Risks of Cancer Oral Contraceptive Use and Risks of Cancer
While oral contraceptive use has been well studied in terms of breast, ovarian, and endometrial cancers, this analysis investigated the total effect of OC use on cancer risk across all organs.American Journal of Epidemiology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - August 24, 2018 Category: Consumer Health News Tags: Ob/Gyn & Women ' s Health Journal Article Source Type: news

Sentinel Lymph Node Mapping Most Cost - Effective for Uterine CA
Findings compared to routine, selective lymphadenectomy for low - risk endometrial cancer (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - August 21, 2018 Category: Cancer & Oncology Tags: Gynecology, Oncology, Radiology, Surgery, Journal, Source Type: news

Sentinel Lymph Node Mapping Most Cost-Effective for Uterine CA
TUESDAY, Aug. 21, 2018 -- Sentinel lymph node mapping has the lowest costs and highest quality-adjusted survival compared to both routine and selective lymphadenectomy for managing low-risk endometrial carcinoma, according to a study published in... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - August 21, 2018 Category: Pharmaceuticals Source Type: news

Most Postmenopausal Bleeding Not Associated With Cancer
TUESDAY, Aug. 14, 2018 -- Most women with postmenopausal bleeding (PMB) will not be diagnosed with endometrial cancer, according to a review published online Aug. 6 in JAMA Internal Medicine. Megan A. Clarke, Ph.D., from the National Cancer... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - August 14, 2018 Category: Pharmaceuticals Source Type: news

Postmenopausal Bleeding and Endometrial Cancer
Postmenopausal Bleeding: Reliable Sign of Endometrial Cancer (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - August 9, 2018 Category: General Medicine Source Type: news

Postmenopausal Bleeding: Reliable Sign of Endometrial Cancer Postmenopausal Bleeding: Reliable Sign of Endometrial Cancer
Almost all women with endometrial cancer have postmenopausal bleeding (PMB), although only a small proportion of women with PMB will be diagnosed with endometrial cancer.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - August 8, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Postmenopausal Bleeding Should Prompt Endometrial Ca Evaluation
(MedPage Today) -- But patient counseling needed, as only 10% of such cases are cancer (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - August 7, 2018 Category: Hematology Source Type: news

How common is endometrial cancer in women with postmenopausal bleeding?
(JAMA Network) Postmenopausal bleeding is a common symptom among most women with endometrial cancer but most women with   postmenopausal bleeding won't be diagnosed with endometrial cancer, findings that raise questions about how to best manage postmenopausal bleeding for the early detection of endometrial cancer. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - August 6, 2018 Category: Cancer & Oncology Source Type: news

Women's Wellness: Endometrial cancer -- risk factors, screening, treatment
DEAR MAYO CLINIC:?My sister, who is 56, recently was diagnosed with early-stage endometrial cancer. I?m wondering if this kind of cancer runs in families. Could I be at risk for it, too? Are there other things that can raise a woman?s risk for endometrial cancer? Are there any screening tests available for it? ANSWER:?An increased [...] (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - July 26, 2018 Category: Databases & Libraries Source Type: news

Extended Tamoxifen May Double Endometrial Cancer Risk
(MedPage Today) -- But observed malignancies were detected early and carried low mortality risk (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - July 10, 2018 Category: Hematology Source Type: news

Top oncologist to study effect of diet on cancer drugs
Siddhartha Mukherjee says trial is first in a series on ‘rethinking human diets for cancer’A groundbreaking clinical trial on whether diet could boost the effectiveness of cancer drugs is set to be launched by one of the world ’s leading oncologists.The work, led bySiddhartha Mukherjee atColumbia University Medical Center in New York, will investigate whether a high-fat, low-carbohydrate diet could improve outcomes for patients with lymphoma and endometrial cancer.Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - July 6, 2018 Category: Science Authors: Hannah Devlin Science correspondent Tags: Cancer research Medical research Siddhartha Mukherjee Science Diets and dieting Health Source Type: news

Breast-cancer drug taken by thousands of women doubles the risk of womb cancer
Researchers from St Vincent's Hospital Group, Dublin, found that taking tamoxifen for 10 years rather than five raises the risk of endometrial cancer from 1.5 per cent to 3.5 per cent. (Source: the Mail online | Health)
Source: the Mail online | Health - July 5, 2018 Category: Consumer Health News Source Type: news

Extended tamoxifen therapy may increase risk of endometrial cancer
(Wiley) There is clear evidence that extended adjuvant tamoxifen therapy for 10 years reduces local recurrence and improves breast cancer-free survival in women with oestrogen receptor-positive breast cancer. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - July 5, 2018 Category: Cancer & Oncology Source Type: news

Olaparib Plus Vistusertib Promising in Early Trial of Endometrial, Other Cancers
Dave LevitanJun 6, 2018The combination of the PARP inhibitor olaparib with the mTORC1/2 inhibitor vistusertib had promising activity across endometrial, ovarian, and triple-negative breast cancers. (Source: CancerNetwork)
Source: CancerNetwork - June 6, 2018 Category: Cancer & Oncology Authors: A Source Type: news

Gene sequencing study finds new cancers linked with Lynch syndrome
CHICAGO (Reuters) - Lynch syndrome, a rare hereditary disease typically associated with an increased risk of colorectal and endometrial cancers, appears to be linked with several additional types of cancer than previously thought, U.S. researchers said on Saturday. (Source: Reuters: Health)
Source: Reuters: Health - June 2, 2018 Category: Consumer Health News Tags: healthNews Source Type: news

CVD Risk Elevated in Endometrial Ca Survivors (CME/CE)
(MedPage Today) -- Call for careful monitoring, risk management for up to 10 years after cancer diagnosis (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - May 13, 2018 Category: Cardiology Source Type: news

Long-Term Cardiovascular Risk for Endometrial Cancer Survivors
TUESDAY, May 8, 2018 -- Endometrial cancer survivors have an elevated risk of various adverse long-term cardiovascular outcomes, according to a study published online May 8 in the Journal of the National Cancer Institute. Sean Soisson, from the... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - May 8, 2018 Category: Pharmaceuticals Source Type: news

Endometrial cancer telephone follow-up, a good call
(Source: PharmacoEconomics and Outcomes News)
Source: PharmacoEconomics and Outcomes News - May 1, 2018 Category: Drugs & Pharmacology Source Type: news

Can Diabetes Lead to Irregular Periods in Teens?
In the long-term, irregular periods can also increase the risk of endometrial cancer, the researchers pointed out in the new report. (Source: WebMD Health)
Source: WebMD Health - April 25, 2018 Category: Consumer Health News Source Type: news

Hologic wins FDA PMA for ThinPrep automated Pap test imager
Hologic (NSDQ:HOLX) said today it won FDA premarket approval for its ThinPrep integrated imager designed for the automated imaging of Pap tests. The Marlborough, Mass.-based company’s ThinPrep imager is designed to aid cytology technicians in identifying abnormal cells, and combines an imaging station and review scope into a single unit. The system takes approximately 90 seconds to analyze samples, the company said. “Approval of the ThinPrep Integrated Imager brings the benefits of ThinPrep automated Pap imaging to small- and mid-sized laboratories in the United States, and of course to their patients...
Source: Mass Device - April 25, 2018 Category: Medical Devices Authors: Fink Densford Tags: Food & Drug Administration (FDA) Imaging Pre-Market Approval (PMA) Women's Health Hologic Source Type: news

Duo win prestigious pathology award for endometrial cancer study
(Source: Karmanos Cancer Institute)
Source: Karmanos Cancer Institute - April 12, 2018 Category: Cancer & Oncology Source Type: news

Studies Seek Role for Anti-PD-1 Drugs in Gyn Cancers
(MedPage Today) -- Activity in resistant ovarian, mutated endometrial cancers (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - March 28, 2018 Category: Hematology Source Type: news

Could ER/GR Interplay Affect Endometrial Cancer Prognosis?
Researchers discovered that estrogen receptor alpha and glucocorticoid receptor are simultaneously expressed in many endometrial cancers, and may be associated with poor prognosis. (Source: CancerNetwork)
Source: CancerNetwork - March 28, 2018 Category: Cancer & Oncology Authors: John Schieszer Tags: Endometrial Cancer News Source Type: news

Everolimus Plus Letrozole Effective in Endometrial Carcinoma
Findings from the GOG-3007 study suggest everolimus plus letrozole might be effective in advanced persistent or recurrent endometrial carcinoma. (Source: CancerNetwork)
Source: CancerNetwork - March 27, 2018 Category: Cancer & Oncology Authors: Bryant Furlow Tags: Endometrial Cancer News Conferences/SGO Source Type: news

The connection between diet, obesity, and cancer: Nutrition experts explore the evidence
(Elsevier) About one third of cancer cases are estimated to be linked to dietary and other modifiable risk factors, especially for obesity-related cancers such as breast, colorectal, ovarian, endometrial, kidney, gallbladder, esophageal, and pancreatic cancers. In this special theme issue of the Journal of the Academy of Nutrition and Dietetics, food and nutrition practitioners and other health professionals take an in-depth look at the relationship between nutrition, obesity, and cancer prevention, treatment, and survival and identify research gaps for future prevention research efforts. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 27, 2018 Category: International Medicine & Public Health Source Type: news

Updating smear tests could save thousands of women's lives
Researchers from  Johns Hopkins University found assessing cervical fluid collected in smears for DNA mutations accurately detects 81 per cent of endometrial and 33 per cent of ovarian cancers. (Source: the Mail online | Health)
Source: the Mail online | Health - March 22, 2018 Category: Consumer Health News Source Type: news

Modified Pap tests can show early warning signs of other gynecological cancers
The Pap test has already reduced the incidence of cervical cancerby more than 60%. Now it may become a key step in the early detection of two other gynecological malignancies — ovarian and endometrial cancers — that have been notorious killers because they’re typically caught so late.A new study... (Source: Los Angeles Times - Science)
Source: Los Angeles Times - Science - March 22, 2018 Category: Science Authors: Melissa Healy Source Type: news

Pap test fluids used in gene-based screening test for two gyn cancers
(Johns Hopkins Medicine) Cervical fluid samples gathered during routine Papanicolaou (Pap) tests are the basis of a new screening test for endometrial and ovarian cancers developed by researchers at the Johns Hopkins Kimmel Cancer Center. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - March 22, 2018 Category: Cancer & Oncology Source Type: news

Could a Pap Test Spot More Than Cervical Cancer?
The researchers behind the new study developed a testing regimen called PapSEEK to see if additional samples collected during a pelvic exam could be used to detect endometrial or ovarian cancer. (Source: WebMD Health)
Source: WebMD Health - March 21, 2018 Category: Consumer Health News Source Type: news

PapSEEK: Potential Screening Test for Gynecologic Cancers PapSEEK: Potential Screening Test for Gynecologic Cancers
A multiplex panel that detects mutations in endometrial and ovarian cancers using samples from a routine Pap test and that also provides an analysis of aneuploidy may emerge as a screening tool.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - March 21, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Surprising discovery provides insights into aggressive endometrial cancers
(Huntsman Cancer Institute) New research from Huntsman Cancer Institute (HCI) at the University of Utah (U of U) indicates steroid and hormone receptors are simultaneously active in many endometrial cancer tissues. The findings, published today in the journal Cell Reports, yield insights about factors that contribute to more aggressive endometrial tumors (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - March 13, 2018 Category: Cancer & Oncology Source Type: news

Switching on survival signalling to drive drug resistance
(Queen Mary University of London) Researchers at Queen Mary University of London have discovered that the loss of a single protein- PHLDA1- is sufficient for the development of drug resistance to a type of targeted therapy in endometrial and HER2-positive breast cancer cells. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - February 27, 2018 Category: Cancer & Oncology Source Type: news

Adjuvant Chemo in Endometrial Cancer: Benefit Only for Some Adjuvant Chemo in Endometrial Cancer: Benefit Only for Some
PORTEC-3 results show that adjuvant chemotherapy improves failure-free survival, although not overall survival, in women with stage III high-risk endometrial cancer, but not in less advanced disease.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - February 22, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Lower Risk of Some Cancers With Oral Contraceptives Applies Across Lifestyles Lower Risk of Some Cancers With Oral Contraceptives Applies Across Lifestyles
Women who use oral contraceptives for at least a decade may be less likely to develop ovarian or endometrial malignancies, and this benefit doesn ’ t seem to be diminished by other lifestyle risk factors, a U.S. study suggests.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - January 31, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Lower risk of certain cancers with the Pill applies across lifestyles
(Reuters Health) - Women who use oral contraceptives for at least a decade may be less likely to develop ovarian or endometrial malignancies, and this benefit doesn ’t seem to be diminished by other lifestyle risk factors, a U.S. study suggests. (Source: Reuters: Health)
Source: Reuters: Health - January 30, 2018 Category: Consumer Health News Tags: healthNews Source Type: news

Vaginal Estrogen for GSM and Risk of Endometrial Cancer Vaginal Estrogen for GSM and Risk of Endometrial Cancer
Concerns remain regarding the safety of low-dose vaginal estrogen for the treatment of genitourinary syndrome of menopause. What does the latest evidence show?Menopause (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 26, 2018 Category: Consumer Health News Tags: Ob/Gyn & Women ' s Health Journal Article Source Type: news

Oral Contraceptives Reduce Risk for Ovarian and Endometrial Cancers
The effect is especially evident in smokers, the obese and those who exercise infrequently. (Source: NYT Health)
Source: NYT Health - January 19, 2018 Category: Consumer Health News Authors: NICHOLAS BAKALAR Tags: Smoking and Tobacco Birth Control and Family Planning Cancer Ovaries Source Type: news

Pill Cuts Ovarian Cancer Risk, Even for Smokers
According to the study from the U.S. National Cancer Institute, these trends were also observed for endometrial cancer as well. (Source: WebMD Health)
Source: WebMD Health - January 18, 2018 Category: Consumer Health News Source Type: news

Conservative Treatment for Some Low-risk Endometrial CA Patients Conservative Treatment for Some Low-risk Endometrial CA Patients
Conservative treatment of low-risk endometrial cancer and complex atypical hyperplasia with the levonorgestrel-releasing intrauterine device (LNG-IUD) appears effective in most patients, according to a retrospective case series.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - December 27, 2017 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Hormonal Therapy in Advanced Endometrial Cancer Hormonal Therapy in Advanced Endometrial Cancer
This meta-analysis may finally clarify which patients are most likely to respond to hormonal therapy.Medscape (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - December 15, 2017 Category: Cancer & Oncology Tags: Hematology-Oncology Commentary Source Type: news

Endometrial Cancer Responsive to Levonorgestrel IUD Therapy Endometrial Cancer Responsive to Levonorgestrel IUD Therapy
Among a small cohort of women with complex atypical hyperplasia and grade 1 and 2 endometrial cancer, 75% responded to conservative treatment with a levonorgestrel IUD, a study found.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - December 14, 2017 Category: Consumer Health News Tags: Ob/Gyn & Women ' s Health News Source Type: news

Case: Metastatic Endometrial Serous Carcinoma to the Breast Case: Metastatic Endometrial Serous Carcinoma to the Breast
This unusual case underscores that while the breast is an atypical target of metastases, it is a possibility that needs to be considered, and should be confirmed histologically.Applied Radiology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - December 11, 2017 Category: Consumer Health News Tags: Hematology-Oncology Journal Article Source Type: news

New Study Reinforces Link Between Birth Control & Breast Cancer Risk
By Meera Senthilingam, CNN (CNN) — Birth control can increase a woman’s risk of breast cancer by up to 38%, depending on how long she has taken it, a new study finds. The risk was associated with all forms of hormonal contraception — such as the pill, injections or IUDs — when compared with women who have never used them. Researchers from the University of Copenhagen analyzed data from 1.8 million women under the age of 50 in Denmark. They followed the women for nearly 11 years, on average. The level of breast cancer risk increased the longer a woman had been taking hormonal contraceptives, with the...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - December 7, 2017 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News birth control Breast Cancer Source Type: news