Can Recurrent Ovarian Cancer Patients Avoid Chemotherapy?
The AVANOVA2 trial enrolled a total of 97 patients with high-grade serous or endometrioid platinum-sensitive recurrent ovarian cancer. (Source: CancerNetwork)
Source: CancerNetwork - September 20, 2019 Category: Cancer & Oncology Authors: Dave Levitan Source Type: news

Project Orbis Enables First International Approval in U.S., Canada, Australia
The first-of-its-kind collaboration led to the approval of a combination therapy for patients with endometrial cancer. (Source: CancerNetwork)
Source: CancerNetwork - September 19, 2019 Category: Cancer & Oncology Authors: Seth Augenstein Source Type: news

US, Canada, Australia Approve Endometrial Cancer Combo US, Canada, Australia Approve Endometrial Cancer Combo
Regulatory agencies in three countries, including the United States, all approved lenvatinib in combination with pembrolizumab for the treatment of patients with advanced endometrial carcinoma.FDA Approvals (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - September 17, 2019 Category: Consumer Health News Tags: Hematology-Oncology News Alert Source Type: news

FDA takes first action under new international collaboration with Australia and Canada designed to provide a framework for concurrent review of cancer therapies, approving treatment for patients with endometrial carcinoma
Project Orbis provides a framework for concurrent submission and review of oncology drugs among its international partners. Under this project, the FDA, Australia and Canada collaboratively reviewed applications for two oncology drugs, allowing for simultaneous decisions in all three countries. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - September 17, 2019 Category: Drugs & Pharmacology Authors: FDA Source Type: news

ASTRO: Cervical cancer deaths rise as women's centers close
CHICAGO - Women in states where family planning clinics have closed received...Read more on AuntMinnie.comRelated Reading: ASTRO: Is hormone therapy after prostate surgery needed? 3D printing customizes brachytherapy for cervical cancer Contrast ultrasound identifies early cervical cancer FDG-PET/CT targets metastases in cervical, endometrial cancer Volumetric MR images boost cervical cancer treatment planning (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - September 17, 2019 Category: Radiology Source Type: news

Pembrolizumab Plus Lenvatinib Approved for Endometrial Cancer
The combination was simulataneously approved in Australia and Canada and was the first such action under a new international collaboration. (Source: CancerNetwork)
Source: CancerNetwork - September 17, 2019 Category: Cancer & Oncology Authors: Erin Kayata Source Type: news

FDA Approves Keytruda (pembrolizumab) plus Lenvima (lenvatinib) Combination Treatment for Patients with Certain Types of Endometrial Carcinoma
KENILWORTH, N.J.,& WOODCLIFF LAKE, N.J.-- September 17, 2019 -- (BUSINESS WIRE)--Merck (NYSE: MRK), known as MSD outside the United States and Canada, and Eisai today announced that the U.S. Food and Drug Administration (FDA) approved the... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - September 17, 2019 Category: Drugs & Pharmacology Source Type: news

Women Who Use IUDs May Be At Lower Risk For Ovarian Cancer, Study Finds
BOSTON (CBS) – Nearly 14,000 American women will die from ovarian cancer this year, but a new study from the UCHealth University of Colorado Hospital finds that women who use IUDs may be at lower risk. The symptoms of ovarian cancer can be mild or vague and there is no reliable screening test, so the diagnosis often isn’t made until it’s pretty advanced. But a new study of thousands of women around the world found that women who use intrauterine devices, or IUDs, for contraception may be 15-32% less likely to develop ovarian cancer. It’s not clear for how long they need to use one or why they may be pro...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - September 11, 2019 Category: Consumer Health News Authors: Health – CBS Boston Tags: Boston News Health Syndicated CBSN Boston Syndicated Local Dr. Mallika Marshall HealthWatch IUD Source Type: news

Mayo Clinic Minute: 3 things women should know about gynecologic cancer
Cancer of a woman's reproductive organs is referred to as "gynecologic cancer." Dr. Amanika Kumar, a Mayo Clinic OB-GYN, says there are many forms of gynecologic cancer: endometrial or uterine, ovarian, vulvar, cervical, and vaginal. Watch: The Mayo Clinic Minute https://youtu.be/G6371uKfois Journalists: Broadcast-quality video pkg (0:58) is in the downloads at the end of the post. [...] (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - September 8, 2019 Category: Databases & Libraries Source Type: news

Is Precision Therapy an Option for Advanced Endometrial Carcinoma?
Researchers identified a highly recurrent, disease-specific PP2A PPP2R1A mutation as a driver of endometrial carcinoma and as a target for new drugs. (Source: CancerNetwork)
Source: CancerNetwork - September 5, 2019 Category: Cancer & Oncology Authors: Naveed Saleh, MD, MS Source Type: news

Adjuvant Chemoradiotherapy May Boost Endometrial-Cancer Survival Adjuvant Chemoradiotherapy May Boost Endometrial-Cancer Survival
Combined adjuvant chemotherapy and radiotherapy appear significantly more effective than pelvic radiotherapy alone for women with high-risk endometrial cancer, according to a post hoc analysis of the PORTEC-3 trial.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - August 14, 2019 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Obesity 'raises cancer risk by TWICE as much as previously thought', study warns
Scientists at the International Agency for Research on Cancer in Lyon, France, found the risk was underestimated for bowel, kidney, pancreatic, endometrial and ovarian cancers. (Source: the Mail online | Health)
Source: the Mail online | Health - August 9, 2019 Category: Consumer Health News Source Type: news

Two Genes Conspire in Endometriosis and Cancer to Help Cells Migrate
The genes promote the migration of endothelial cells outside of the uterus, a characteristic of both endometriosis and endometrial cancers, a study of mice and human tissue finds. (Source: The Scientist)
Source: The Scientist - August 9, 2019 Category: Science Tags: News & Opinion Source Type: news

Podcast: Use of computer or robotic technology to assist surgeons in performing gynaecological surgery
In conclusion, low-certainty evidence for hysterectomy and sacrocolpopexy operations suggests that complication rates for robot-assisted surgery might be similar to those for conventional laparoscopic surgery. Things are more uncertain for gynaecological cancer, where we found no comparative evidence on cancer recurrence or survival after the surgery. As robot-assisted surgery depends on the skill and experience of the surgeon and is expensive, evaluating its effectiveness and safety continues to present a challenge; but this needs to be met if we are to have reliable evidence on its potential benefits and harms.Read the C...
Source: Cochrane News and Events - August 9, 2019 Category: Information Technology Authors: Lydia Parsonson Source Type: news

Guardant Brings Home Strong Results as Liquid Biopsy Space Heats Up
Guardant Health is one of the biggest names in liquid biopsy and after Monday its presence in the space can only increase. The Redwood City, CA-based company revealed results of a study conducted by it along with researchers from The University of Texas MD Anderson Cancer Center, the Samsung Medical Center, and other institutions. Results show the Guardant360 assay can accurately detect microsatellite instability status (MSI) as accurately as tissue biopsy. The company said this is the largest comparison of MSI testing to traditional tissue methods across multiple solid tumor types. Findings were reported in Cl...
Source: MDDI - August 5, 2019 Category: Medical Devices Authors: Omar Ford Tags: IVD Source Type: news