Quiz: Multiple Myeloma Patients With AL Amyloidosis
Challenge yourself with our latest quiz covering management of AL amyloidosis in the treatment of patients with multiple myeloma. (Source: CancerNetwork)
Source: CancerNetwork - December 10, 2018 Category: Cancer & Oncology Source Type: news

Can Staging for Lung Cancer Better Guide Treatment Decisions?
Researchers found that patients with stage I/II lung cancer have relatively long-term survival when treated with chemoradiotherapy, calling into question the practice of combining these patients with stage III patients. (Source: CancerNetwork)
Source: CancerNetwork - December 10, 2018 Category: Cancer & Oncology Authors: Dave Levitan Source Type: news

Two Chemo/RT Regimens Provide Bladder-Sparing Options in Bladder Cancer
A new study compared two chemotherapy/radiotherapy approaches with regard to distant metastasis –free survival in bladder cancer. (Source: CancerNetwork)
Source: CancerNetwork - December 10, 2018 Category: Cancer & Oncology Authors: Dave Levitan Source Type: news

Is Partial Breast Irradiation as Good as Whole Breast Irradiation?
In looking to improve quality of life, researchers studied whether partial breast irradiation was just as effective as whole breast irradiation. (Source: CancerNetwork)
Source: CancerNetwork - December 7, 2018 Category: Cancer & Oncology Authors: Dave Levitan Source Type: news

Novel Immunotherapy for Primary Hemophagocytic Lymphohistiocytosis
Results of a study evaluating the safety and efficacy of a promising new agent were presented at ASH 2018. (Source: CancerNetwork)
Source: CancerNetwork - December 7, 2018 Category: Cancer & Oncology Authors: Naveed Saleh, MD, MS Source Type: news

Can Radiotherapy Reduce the Need for Axillary Surgery?
The AMAROS trial tested RT to the axillary lymph node against ALND to see if some of the morbidity associated with surgery for breast cancer could be avoided. (Source: CancerNetwork)
Source: CancerNetwork - December 7, 2018 Category: Cancer & Oncology Authors: Dave Levitan Source Type: news

What Effect Do Surgical Choices Have on Quality of Life in Young Breast Cancer Survivors?
Unilateral or bilateral mastectomy can have a significant effect on quality of life when compared with breast-conserving surgery in young breast cancer survivors. (Source: CancerNetwork)
Source: CancerNetwork - December 7, 2018 Category: Cancer & Oncology Authors: Dave Levitan Source Type: news

Cancer Network Conferences
(Source: CancerNetwork)
Source: CancerNetwork - December 7, 2018 Category: Cancer & Oncology Source Type: news

Is Cardiac Prophylaxis Effective in Early HER2+ Breast Cancer Patients?
In patients with HER2-positive breast cancer treated with anthracyclines plus trastuzumab, can adding lisinopril or carvedilol reduce the risk of cardiotoxicity? (Source: CancerNetwork)
Source: CancerNetwork - December 7, 2018 Category: Cancer & Oncology Authors: Dave Levitan Source Type: news

Testing a Lifestyle Intervention to Improve Outcomes in Early Breast Cancer
A study of a lifestyle intervention looked for improvement in disease-free or overall survival in early breast cancer patients. (Source: CancerNetwork)
Source: CancerNetwork - December 7, 2018 Category: Cancer & Oncology Authors: Dave Levitan Source Type: news

Quiz: Evaluating Skin Cancer Risk Factors
How much do you know about prominent skin cancer risk factors? Take our latest quiz to sharpen your knowledge. (Source: CancerNetwork)
Source: CancerNetwork - December 6, 2018 Category: Cancer & Oncology Source Type: news

What Is Required for Accurate Lymph Node Staging in Small-Bowel NETs?
Among patients with small-bowel neuroendocrine tumors, accurate lymph node staging may require the examination of at least eight lymph nodes. (Source: CancerNetwork)
Source: CancerNetwork - December 6, 2018 Category: Cancer & Oncology Authors: Dave Levitan Source Type: news

Does a Cancer Diagnosis Increase Suicide Risk?
Researchers in England investigated whether risk for suicide was elevated in cancer patients, and which cancer types might have the greatest risk. (Source: CancerNetwork)
Source: CancerNetwork - December 6, 2018 Category: Cancer & Oncology Authors: Lori Smith, BSN, MSN, CRNP Source Type: news

Can Low-Dose Tamoxifen Prevent Recurrences With Reduced Toxicity?
The TAM01 trial looked at whether a 5-mg/day dose of tamoxifen was effective in patients with breast intraepithelial neoplasia, or if the 20-mg/day dose was still the best option. (Source: CancerNetwork)
Source: CancerNetwork - December 6, 2018 Category: Cancer & Oncology Authors: Dave Levitan Source Type: news

The Long-Term Outlook for Mogamulizumab in Previously Treated Cutaneous T-Cell Lymphoma
The results of a follow-up analysis to the phase III  MAVORIC study were presented at the ASH 2018 Annual Meeting& Exposition. (Source: CancerNetwork)
Source: CancerNetwork - December 6, 2018 Category: Cancer & Oncology Authors: Traci DeVito Source Type: news

Impact of Checkpoint Blockade Therapy on Subsequent Treatment in Non-Hodgkin Lymphoma Patients
Research presented at ASH 2018 examined whether checkpoint blockade therapy sensitizes patients with relapsed/refractory NHL to consequent treatment. (Source: CancerNetwork)
Source: CancerNetwork - December 6, 2018 Category: Cancer & Oncology Authors: Naveed Saleh, MD, MS Source Type: news

A 54-Year-Old With a Mediastinal Mass
A 54-year-old man presents with chest pain, cough, shortness of breath, and a mediastinal mass. What is your diagnosis? (Source: CancerNetwork)
Source: CancerNetwork - December 6, 2018 Category: Cancer & Oncology Authors: Cesar A. Moran, MD Source Type: news

Gene Signature Identifies New Subgroup of DLBCL
A new study has identified a clinically and biologically distinct subgroup of diffuse large B-cell lymphoma tumors. (Source: CancerNetwork)
Source: CancerNetwork - December 6, 2018 Category: Cancer & Oncology Authors: Leah Lawrence Source Type: news

Do Training-Guided Survivorship Visits Benefit DLBCL Patients?
A study looked at whether survivorship care plans were able to enhance patients'knowledge and adherence to physician recommendations. (Source: CancerNetwork)
Source: CancerNetwork - December 6, 2018 Category: Cancer & Oncology Authors: Leah Lawrence Source Type: news

Can Anthracyclines be Excluded From Neoadjuvant HER2+ Breast Cancer Tx?
A comparison of chemotherapy regimens plus anti-HER2 therapy in the neoadjuvant setting tested whether the addition of anthracyclines is necessary for patients with HER2-positive breast cancer. (Source: CancerNetwork)
Source: CancerNetwork - December 5, 2018 Category: Cancer & Oncology Authors: Dave Levitan Source Type: news

Can Venetoclax Plus R-CHOP Improve Outcomes in Aggressive DLBCL?
The results of the single-arm, multicenter, phase II part of the CAVALLI trial were presented at the 2018 ASH Annual Meeting& Exposition in San Diego. (Source: CancerNetwork)
Source: CancerNetwork - December 5, 2018 Category: Cancer & Oncology Authors: Naveed Saleh, MD, MS Source Type: news

Acquired Mutation in BCL2 Confers Resistance to Tx in Progressive CLL
Researchers analyzed a new recurrentBCL2 mutation appearing in a cohort of patients with CLL-type progressions treated with venetoclax. (Source: CancerNetwork)
Source: CancerNetwork - December 5, 2018 Category: Cancer & Oncology Authors: Naveed Saleh, MD, MS Source Type: news

Does Adding Daratumumab Benefit Transplant-Ineligible Myeloma Patients?
Researchers examined adding daratumumab to standard of care in newly diagnosed transplant-ineligible myeloma patients. (Source: CancerNetwork)
Source: CancerNetwork - December 5, 2018 Category: Cancer & Oncology Authors: Naveed Saleh, MD, MS Source Type: news

Managing Afib in Cancer Patients Taking BTK Inhibitors
Cancer Network speaks with Dr. Leon Ptaszek about managing cancer patients who have atrial fibrillation and are being treated with BTK inhibitors. (Source: CancerNetwork)
Source: CancerNetwork - December 5, 2018 Category: Cancer & Oncology Authors: Leon M. Ptaszek, MD, PhD Source Type: news

Do Oral Side Effects Affect Fentanyl Delivery in Head & amp; Neck Cancer Patients?
Erin McMenamin, CRNP, of Penn Medicine, discusses how oral side effects affect head and neck cancer patients. (Source: CancerNetwork)
Source: CancerNetwork - December 4, 2018 Category: Cancer & Oncology Authors: Lori Smith, BSN, MSN, CRNP Source Type: news

Acquired Mutation in BCL2 Confers Resistance to Tx in Progressive CML
Researchers analyzed a new recurrentBCL2 mutation appearing in a cohort of patients with CLL-type progressions treated with venetoclax. (Source: CancerNetwork)
Source: CancerNetwork - December 4, 2018 Category: Cancer & Oncology Authors: Naveed Saleh, MD, MS Source Type: news

How Does Prognosis of NETs Differ Based on Site of Origin?
An analysis of more than 70,000 patients revealed significant differences with regard to survival between different sites of origin for neuroendocrine tumors. (Source: CancerNetwork)
Source: CancerNetwork - December 4, 2018 Category: Cancer & Oncology Authors: Dave Levitan Source Type: news

Uncovering Novel Data on Myeloma Patients Treated With Proteasome Inhibitors
Researchers uncovered distinct clinical characteristics in relapsed/refractory multiple myeloma patients receiving proteasome inhibitors. (Source: CancerNetwork)
Source: CancerNetwork - December 4, 2018 Category: Cancer & Oncology Authors: Naveed Saleh, MD, MS Source Type: news

Using Clonal Hematopoiesis to Assess Risk in Lymphoma Patients
Researchers studied clonal hematopoiesis of indeterminate potential (CHIP) as a way to assess risk for increased mortality in lymphoma patients. (Source: CancerNetwork)
Source: CancerNetwork - December 4, 2018 Category: Cancer & Oncology Authors: Naveed Saleh, MD, MS Source Type: news

New Combo Therapy Shows Promise in Leukemia
Leukemia cells show sensitivity to restriction of BCL2 and BTK with the combination of venetoclax and ibrutinib. (Source: CancerNetwork)
Source: CancerNetwork - December 4, 2018 Category: Cancer & Oncology Authors: Naveed Saleh, MD, MS Source Type: news

A Better Risk Model for DLBCL Patients?
Researchers developed an enhanced genomic model combining clinical factors and select gene mutations in order to better predict survival in patients with DLBCL who were administered first-line R-CHOP. (Source: CancerNetwork)
Source: CancerNetwork - December 4, 2018 Category: Cancer & Oncology Authors: Naveed Saleh, MD, MS Source Type: news

Single or Double Autologous Transplantation in New Myeloma Cases?
Researchers analyzed double vs single autologous stem cell transplantation in patients with newly diagnosed multiple myeloma, after previous conflicting results. (Source: CancerNetwork)
Source: CancerNetwork - December 2, 2018 Category: Cancer & Oncology Authors: Naveed Saleh, MD, MS Source Type: news

Meet & amp; Greet the ONCOLOGY Board Members and Editorial Team at ASH 2018
TheONCOLOGY team invites you to attend a meet and greet event with our team and members of our expert Advisory Board at the 60th American Society of Hematology (ASH) 2018 meeting in San Diego, California. Appetizers and drinks will be served!Meet the following hematology/oncology experts:Julie M. Vose, MD, MBA, FACP, FASCOJohn Sweetenham, MD, FRCPStephen T. Rosen, MDEvent DetailsDate: Saturday, December 1, 2018 (Source: CancerNetwork)
Source: CancerNetwork - December 1, 2018 Category: Cancer & Oncology Source Type: news

Allogeneic Transplantation in Elderly AML Patients
Allogeneic hematopoietic stem cell transplantation could improve outcomes of elderly patients with acute myeloid leukemia. (Source: CancerNetwork)
Source: CancerNetwork - November 30, 2018 Category: Cancer & Oncology Authors: Naveed Saleh, MD, MS Source Type: news

Early Intervention With New Drug Combo Beneficial in Myeloma?
This study looked at the benefit of early therapeutic intervention with the combination of elotuzumab, lenalidomide, and dexamethasone in patients with high-risk smoldering multiple myeloma. (Source: CancerNetwork)
Source: CancerNetwork - November 30, 2018 Category: Cancer & Oncology Authors: Naveed Saleh, MD, MS Source Type: news

Screening LSCs For AML Drug Resistance, Sensitivity
Researchers used high throughput drug screening on leukemic stem cells to determine drug resistance and sensitivity in acute myeloid leukemia patients. (Source: CancerNetwork)
Source: CancerNetwork - November 30, 2018 Category: Cancer & Oncology Authors: Naveed Saleh, MD, MS Source Type: news

Can a Third-Generation ALK Inhibitor Improve Outcomes in NSCLC?
In this phase II trial, researchers tested the efficacy of lorlatinib in six expansion cohorts of NSCLC patients based on ALK mutation status and prior treatment. (Source: CancerNetwork)
Source: CancerNetwork - November 30, 2018 Category: Cancer & Oncology Authors: Dave Levitan Source Type: news

How Useful Are Immune Checkpoint Markers in Squamous Cell Carcinoma?
A recent study examined the literature on whether immune checkpoint molecules improve overall survival in oral squamous cell carcinoma. (Source: CancerNetwork)
Source: CancerNetwork - November 29, 2018 Category: Cancer & Oncology Authors: Naveed Saleh, MD, MS Source Type: news

Quiz: 2018 Oncofertility Trends and Statistics
How much do you know about the latest in oncofertility research? Take our latest quiz to test your knowledge. (Source: CancerNetwork)
Source: CancerNetwork - November 28, 2018 Category: Cancer & Oncology Source Type: news

Can KRAS Mutation Status Guide Nivolumab Therapy in NSCLC?
This trial looked at the efficacy of nivolumab in a cohort of patients who were evaluated forKRAS mutations to test whether mutation status had an effect on outcomes. (Source: CancerNetwork)
Source: CancerNetwork - November 28, 2018 Category: Cancer & Oncology Authors: Dave Levitan Source Type: news

Nab-Paclitaxel an Option for Second-Line Advanced NSCLC?
The ABOUND.2L+ trial tested the combination of nab-paclitaxel and CC-486 vs single-agent nab-paclitaxel in patients with advanced NSCLC. (Source: CancerNetwork)
Source: CancerNetwork - November 28, 2018 Category: Cancer & Oncology Authors: Dave Levitan Source Type: news

Are Patients Willing to Travel for Cancer Surgery?
Survey results published inJAMA Network Openlooked at motivating factors behind patient travel and how far they were willing to go for treatment. (Source: CancerNetwork)
Source: CancerNetwork - November 28, 2018 Category: Cancer & Oncology Authors: Leah Lawrence Source Type: news

Does Ovarian Cancer Screening Actually Improve Survival?
A screening study that began more than 30 years ago looked at ultrasound screening for at-risk women for ovarian cancer and its effects on disease-specific survival. (Source: CancerNetwork)
Source: CancerNetwork - November 27, 2018 Category: Cancer & Oncology Authors: Dave Levitan Source Type: news

Is the FDA ’s Biosimilar Action Plan Adequate?
Gary H. Lyman, MD, MPH, says the plan does not address several significant concerns, such as delay tactics that limit prompt access to biosimilars. (Source: CancerNetwork)
Source: CancerNetwork - November 27, 2018 Category: Cancer & Oncology Authors: Naveed Saleh, MD, MS Source Type: news

Do Targeted Agents Aid Melanoma Immunotherapy?
Guy Ben-Betzalel, MD spoke withCancer Network about the emerging role of targeted BRAF+MEK inhibition in antitumor immunity. (Source: CancerNetwork)
Source: CancerNetwork - November 27, 2018 Category: Cancer & Oncology Authors: Bryant Furlow Source Type: news

Emerging Targets in Cancer Immunotherapy
Professor Lana E. Kandalaft,  PharmD, PhD spoke withCancer Network about the next generation of cancer immunotherapy. (Source: CancerNetwork)
Source: CancerNetwork - November 27, 2018 Category: Cancer & Oncology Authors: Bryant Furlow Source Type: news

Early Insights into Biosimilar Cost Savings in the United States
A recent study inJAMA Oncologyexamined the average daily cost of  biosimilar filgrastim-sndz compared with the brand name biologic. (Source: CancerNetwork)
Source: CancerNetwork - November 27, 2018 Category: Cancer & Oncology Authors: Christina Bennett, MS Source Type: news

R-Chop Viable For First-Line Tx of follicular lymphoma?
A study investigates whether R-Chop is a viable first-line treatment for patients with advanced follicular lymphoma. (Source: CancerNetwork)
Source: CancerNetwork - November 27, 2018 Category: Cancer & Oncology Authors: Leah Lawrence Source Type: news

Efficacy of Rituximab Biosimilar in Follicular Lymphoma
A phase III study looks at the efficacy and safety of rituximab biosimilar CT-P10 in patients with follicular lymphoma. (Source: CancerNetwork)
Source: CancerNetwork - November 27, 2018 Category: Cancer & Oncology Authors: Leah Lawrence Source Type: news

A 44-Year-Old Woman With a Neck Mass
A 44-year-old woman presents with a mass in the right side of the neck. The patient complains of general malaise and a cough. What is your diagnosis? (Source: CancerNetwork)
Source: CancerNetwork - November 21, 2018 Category: Cancer & Oncology Authors: Cesar A. Moran, MD Source Type: news