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NIH researchers find potential genetic cause of Cushing syndrome
Finding may lead to therapies that prevent pituitary tumor recurrence. (Source: National Institutes of Health (NIH) News Releases)
Source: National Institutes of Health (NIH) News Releases - June 1, 2017 Category: American Health Source Type: news

Mayo Clinic PathWays: What's the diagnosis?
This week's case study reviews slides from a 53-year-old woman with a two-month history of facial swelling, unintentional weight gain, hirsutism and easy bruising. A diagnosis of ectopic Cushing's syndrome was made, and a CT scan of the chest revealed a mass. Can you make the diagnosis? View the case and make your diagnosis. Learn [...] (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - March 29, 2017 Category: Databases & Libraries Source Type: news

Hair Sample Might Aid in Cushing's Syndrome Diagnosis Hair Sample Might Aid in Cushing's Syndrome Diagnosis
A 1-cm hair sample closest to the scalp was found to be a potential marker for hypercortisolemia in patients suspected of having Cushing's syndrome.Medscape Medical News (Source: Medscape Diabetes Headlines)
Source: Medscape Diabetes Headlines - February 13, 2017 Category: Endocrinology Tags: Diabetes & Endocrinology News Source Type: news

Medical News Today: Cushing's syndrome: Could analyzing hair confirm diagnosis?
Researchers from the National Institutes of Health find that cortisol levels detected in hair might be able to confirm a diagnosis of Cushing's syndrome. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 10, 2017 Category: Consumer Health News Tags: Endocrinology Source Type: news

Hair test for Cushing's syndrome?
Cortisol levels in hair may be used in diagnosis of Cushing's syndrome, according to research in theInternational Journal of Basic and Clinical Endocrinology. The study found that cortisol levels in hair samples correlated with blood and urine samples.MedPage Today (Source: Society for Endocrinology)
Source: Society for Endocrinology - February 9, 2017 Category: Endocrinology Source Type: news

Hair Test for Cushing Syndrome?
(MedPage Today) -- Cortisol levels in hair correlated strongly with standard tests (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - February 9, 2017 Category: Primary Care Source Type: news

Hair analysis may help diagnose Cushing Syndrome, NIH researchers report
Small study suggests that high cortisol level in hair may foretell hard-to-diagnose disorder. (Source: National Institutes of Health (NIH) News Releases)
Source: National Institutes of Health (NIH) News Releases - February 8, 2017 Category: American Health Source Type: news

What are Potential Health Problems Associated with Polycystic Ovary Syndrome?
DiscussionPolycystic ovary syndrome (PCOS) affects 6-8% of reproductive-age women making it the most common endocrinopathy in this age group. There is no consensus on the specific diagnostic criteria for PCOS in adolescents as many of the characteristics overlap with normal adolescent physiology. However, patients should have evidence of hyperandrogenism, oligo- or amenorrhea, and potentially polycystic ovaries. PCOS has a genetic component although a specific gene has not been identified. Incidence of PCOS is 20-40% for a woman with a family history. Hyperandrogenism Androgen levels change during puberty therefore actual ...
Source: PediatricEducation.org - December 5, 2016 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Children with Cushing syndrome have higher suicide risk, study says
Stephen FellerBETHESDA, Md., March 29 (UPI) -- Researchers say doctors should more proactively screen children with Cushing syndrome for depression after treatment because of an increased risk for suicide. (Source: Health News - UPI.com)
Source: Health News - UPI.com - March 29, 2016 Category: Consumer Health News Source Type: news

Children with Cushing syndrome may have higher suicide risk
Children with Cushing syndrome may be at higher risk for suicide as well as for depression, anxiety and other mental health conditions long after their disease has been successfully treated, according to a study. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - March 29, 2016 Category: Science Source Type: news

Children with Cushing syndrome may have higher suicide risk
NIH study finds that depression, anxiety and suicidal thoughts increase after treatment. (Source: National Institutes of Health (NIH) News Releases)
Source: National Institutes of Health (NIH) News Releases - March 29, 2016 Category: American Health Source Type: news

Children with Cushing syndrome may have higher suicide risk
(NIH/Eunice Kennedy Shriver National Institute of Child Health and Human Development) Children with Cushing syndrome may be at higher risk for suicide as well as for depression, anxiety and other mental health conditions long after their disease has been successfully treated, according to a study by researchers at the National Institutes of Health. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 29, 2016 Category: Global & Universal Source Type: news

Children with Cushing syndrome may have higher suicide risk
NIH study finds that depression, anxiety and suicidal thoughts increase after treatment. (Source: National Institutes of Health (NIH) News Releases)
Source: National Institutes of Health (NIH) News Releases - March 28, 2016 Category: American Health Source Type: news

Lizzie Denison-Ward who gained 6st is horrified to discover a BRAIN TUMOUR
Lizzie Denison-Ward, 20, of Lincoln, was found to have Cushing's syndrome - where a brain tumour pressing on her pituitary gland caused a hormone imbalance that led to weight gain. (Source: the Mail online | Health)
Source: the Mail online | Health - November 12, 2015 Category: Consumer Health News Source Type: news

Urinary free cortisol measurement most accurate first-line test for Cushing's syndrome diagnosis
Measuring 24-hour urinary free cortisol with liquid chromatography-mass spectrometry is the most accurate first-line diagnostic tool for diagnosing Cushing’s syndrome in adults, according to research published in The Journal of Clinical Endocrinology & Metabolism. Healio (Source: Society for Endocrinology)
Source: Society for Endocrinology - August 19, 2015 Category: Endocrinology Source Type: news

Pediatric Cushing's Disease Due to Corticotroph HyperplasiaPediatric Cushing's Disease Due to Corticotroph Hyperplasia
This report describes a rare case of Cushing's syndrome caused by corticotroph hyperplasia in a pediatric patient. BMC Endocrine Disorders (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - August 7, 2015 Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news

New Guidelines Address Cushing's Syndrome TreatmentNew Guidelines Address Cushing's Syndrome Treatment
New guidelines from the Endocrine Society call for surgery as first-line treatment but also emphasize individualization and patient participation in decision making. Medscape Medical News (Source: Medscape Diabetes Headlines)
Source: Medscape Diabetes Headlines - August 5, 2015 Category: Endocrinology Tags: Diabetes & Endocrinology News Source Type: news

New guideline for Cushing's syndrome recommends tumour removal
The Endocrine Society and the European Society for Endocrinology have released a new clinical practice guideline for managing Cushing’s syndrome. The guideline recommends umor removal as a first-line treatment unless surgery is not possible or will not help with the excess levels of cortisol. The full guideline is available in the Journal of Clinical Endocrinology & Metabolism. (Source: Society for Endocrinology)
Source: Society for Endocrinology - August 3, 2015 Category: Endocrinology Source Type: news

Experts recommend tumor removal as first-line treatment for Cushing's syndrome
(The Endocrine Society) The Endocrine Society today issued a Clinical Practice Guideline on strategies for treating Cushing's syndrome, a condition caused by overexposure to the hormone cortisol. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 29, 2015 Category: Global & Universal Source Type: news

Bilateral Adrenal Incidentalomas Linked to Cushing SyndromeBilateral Adrenal Incidentalomas Linked to Cushing Syndrome
Subclinical Cushing syndrome is more likely among patients with bilateral adrenal incidentalomas than among those with unilateral lesions, but surgery may not be the best approach to management. Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - July 25, 2015 Category: Consumer Health News Tags: General Surgery News Source Type: news

Predictors of Quality of Life in Treated Cushing's DiseasePredictors of Quality of Life in Treated Cushing's Disease
Do patients with biochemical remission in Cushing syndrome actually feel like they're in remission? Clinical Endocrinology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 18, 2015 Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news

Fat Distribution and Metabolic Changes in Cushing's SyndromeFat Distribution and Metabolic Changes in Cushing's Syndrome
Does remission of Cushing's syndrome affect adipose distribution? Clinical Endocrinology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 9, 2015 Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news

Plant extract fights brain tumor
Silibinin from milk thistle seeds could be a novel, non-invasive treatment strategy for Cushing Disease. Cushing Disease, not to be confused with Cushing's Syndrome, is caused by a tumor in the pituitary gland in the brain. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - February 11, 2015 Category: Science Source Type: news

US Leads Cushing Syndrome Market Prevalent Cases to 2023 Says a New...
RnRMarketResearch.com adds “EpiCast Report Cushing’s Syndrome - Epidemiology Forecast to 2023” to its store. The diagnosed prevalent cases of CS in the 6MM, from 32,634 diagnosed prevalent cases in...(PRWeb October 31, 2014)Read the full story at http://www.prweb.com/releases/cushings-syndrome-market/epidemiology-forecast/prweb12293228.htm (Source: PRWeb: Medical Pharmaceuticals)
Source: PRWeb: Medical Pharmaceuticals - November 1, 2014 Category: Pharmaceuticals Source Type: news

Cushing's syndrome: LCSB researchers characterize a new tumor syndrome
(University of Luxembourg) Scientists at the Luxembourg Centre for Systems Biomedicine of the University of Luxembourg have published their findings that mutations in a gene known as 'ARMC5' promote the growth of benign tumors in the adrenal glands and on the meninges: ARMC5 appears to belong to the group of so-called tumor suppressor genes. It is the first time in years that scientists have characterized such a gene. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 13, 2014 Category: Global & Universal Source Type: news

EU Looks to Okay Ketoconazole for Use in Cushing's SyndromeEU Looks to Okay Ketoconazole for Use in Cushing's Syndrome
Patients with Cushing's syndrome are close to gaining access to ketoconazole in the European Union, following the EMA's decision to recommend approval of the agent for this condition. International Approvals (Source: Medscape Diabetes Headlines)
Source: Medscape Diabetes Headlines - September 26, 2014 Category: Endocrinology Tags: Diabetes & Endocrinology News Alert Source Type: news

Hustle and bustle at ICE/ENDO 2014
I arrived at McCormick Place to find all the usual hustle and bustle associated with ENDO. I queued, picked up my chic (!) backpack and rushed off to hang my poster. I also had a chance to take a peak at the history of endocrinology timeline as the Endocrine Society approaches it's centenary.  ENDO2014 was officially kicked off yesterday by Robert Lefkowitz who gave us an insightful tour through his lifetime's research on seven transmembrane receptors. His more recent discoveries on B-arrestins were fascinating. I bumped into Sam Mirczuk, Chair of the YE committee in this session :) John Newell-Price dis...
Source: Society for Endocrinology - July 2, 2014 Category: Endocrinology Source Type: news

Cushing Syndrome
(Source: eMedicineHealth.com)
Source: eMedicineHealth.com - June 20, 2014 Category: Journals (General) Source Type: news

Response in Cushing's Syndrome Treated With Mifepristone Response in Cushing's Syndrome Treated With Mifepristone
What are strong drivers of response to mifepristone therapy in patients with Cushing disease? Clinical Endocrinology (Source: Medscape Diabetes Headlines)
Source: Medscape Diabetes Headlines - April 10, 2014 Category: Endocrinology Tags: Diabetes & Endocrinology Journal Article Source Type: news

Diagnosis and Differential Diagnosis of Cushing's SyndromeDiagnosis and Differential Diagnosis of Cushing's Syndrome
Read about the misadventures in diagnosis of this Cushingoid patient. Clinical Endocrinology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 17, 2014 Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news

Cushing's syndrome: A genetic basis for cortisol excess
An international team of researchers led by an endocrinologist at Ludwig-Maximilians-Universitaet (LMU) in Munich has identified genetic mutations that result in uncontrolled synthesis and secretion of the stress hormone cortisol. Cortisol is a hormone that is produced by the adrenal gland in response to stressful events, and modulates a whole spectrum of physiological processes. An international research collaboration has now identified genetic mutations that lead to the production and secretion of cortisol in the absence of an underlying stressor. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 28, 2014 Category: Consumer Health News Tags: Endocrinology Source Type: news

Cushing's syndrome: Genetic basis for cortisol excess
Cushing’s syndrome has been found to be linked to a genetic basis for cortisol excess. Cortisol is a hormone that is produced by the adrenal gland in response to stressful events, and modulates a whole spectrum of physiological processes. An international research collaboration has now identified genetic mutations that lead to the production and secretion of cortisol in the absence of an underlying stressor. This condition, known as Cushing's syndrome, can be successfully treated by surgical removal of the affected adrenal gland. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - February 27, 2014 Category: Science Source Type: news

NIH researchers identify mutation linked to severe form of Cushing's syndrome
Mutation in related gene found in patient with Carney Complex. (Source: National Institutes of Health (NIH) News Releases)
Source: National Institutes of Health (NIH) News Releases - February 27, 2014 Category: American Health Source Type: news

Well: Think Like a Doctor: Red Herrings Solved!
Readers solve the case of a 29-year-old woman with an injured groin, a swollen foot and long list of other abnormalities.     (Source: NYT)
Source: NYT - January 18, 2014 Category: American Health Authors: By LISA SANDERS, M.D. Tags: Cushing's Syndrome Doctors Hormones Think Like a Doctor ACTH (Adrenocorticotropic Hormone) Featured Cortisol (Hormone) Source Type: news

Genetic screening to find 'silent carriers' of adrenal Cushing's syndrome
Genetic research published in the New England Journal of Medicine suggests to Dr. Andre Lacroix, professor at the University of Montreal, that clinicians' understanding and treatment of a form of Cushing's syndrome affecting both adrenal glands will be fundamentally changed, and that moreover, it might be appropriate to begin screening for the genetic mutations that cause this form of the disease. "Screening family members of bilateral adrenal Cushing's syndrome patients with genetic mutations may identify affected silent carriers," Lacroix said in an editorial in this Journal. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - December 2, 2013 Category: Consumer Health News Tags: Genetics Source Type: news

Genetic Studies Shed Light on Cushing's Syndrome
(MedPage Today) -- Some cases of corticotropin-independent macronodular adrenal hyperplasia occur as a result of inactivating mutations in what appears to be a tumor-suppressor gene, a study reported, while another group of researchers found that the disease may be regulated by corticotropin. (Source: MedPage Today Endocrinology)
Source: MedPage Today Endocrinology - December 1, 2013 Category: Endocrinology Source Type: news

Two Copies of Mutant Gene May Trigger Rare Adrenal Disorder
Source: National Institute of Child Health and Human Development - Related MedlinePlus Page: Cushing's Syndrome (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - November 29, 2013 Category: Consumer Health News Source Type: news

New Studies Shed Light on Cushing's SyndromeNew Studies Shed Light on Cushing's Syndrome
Two early research studies have identified a gene mutation and abnormal receptors in the adrenal gland that are implicated in Cushing's syndrome and might lead to future screening and treatment strategies. Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 29, 2013 Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news

Abortion Drug Aids in Cushing's Syndrome (CME/CE)
(MedPage Today) -- Treatment of patients with refractory Cushing's syndrome using the glucocorticoid receptor antagonist mifepristone led to improvements in global clinical response, a post-hoc analysis found. (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - September 23, 2013 Category: Cardiology Source Type: news

MR Brain Spectroscopy Detects Damage In The Hippocampus Of Patients Exposed To Excess Cortisol
New research shows that patients who are "biochemically cured" of Cushing's syndrome have levels of brain metabolites which are associated with neural damage. This will have implications for treatment of Cushing's patients, but might also suggest that patients using high levels of glucocorticoid drugs may suffer similar long-term problems. The work was presented yesterday at the European Congress of Endocrinology in Copenhagen. Cushing's syndrome is an endocrine disease causing an overproduction of the stress hormone cortisol... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - May 2, 2013 Category: Consumer Health News Tags: Endocrinology Source Type: news

Korlym (Mifepristone) for Treatment of Endogenous Cushing’s Syndrome
Korlym (mifepristone) is a glucocorticoid receptor blocker indicated for the control of high blood sugar levels in adult patients suffering from endogenous Cushing's syndrome. (Source: Drug Development Technology)
Source: Drug Development Technology - April 25, 2013 Category: Pharmaceuticals Source Type: news

Medical Management of Cushing's SyndromeMedical Management of Cushing's Syndrome
Medications used for Cushing disease include an antifungal, anticonvulsant, and dopamine agonist. Expert Review of Endocrinology and Metabolism (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - April 15, 2013 Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news

Cushing syndrome
— Comprehensive overview covers symptoms, treatment of this disorder caused by excess cortisol. (Source: MayoClinic.com Full Feed)
Source: MayoClinic.com Full Feed - March 29, 2013 Category: Consumer Health News Source Type: news