Decompression sickness followed by diabetic ketoacidosis and sepsis shock: an unusual case report
Undersea Hyperb Med. 2024 First Quarter;51(1):41-46.ABSTRACTDecompression sickness (DCS) is caused by abrupt changes in extracorporeal pressure with varying severity. Symptoms range from mild musculoskeletal pain to severe organ dysfunction and death, especially among patients with chronic underlying disease. Here, we report an unusual case of a 49-year-old man who experienced DCS after a dive to a depth of 38 meters. The patient's symptoms progressed, starting with mild physical discomfort that progressed to disturbance of consciousness on the second morning. During hospitalization, we identified that in addition to DCS, ...
Source: Undersea and Hyperbaric Medicine - April 14, 2024 Category: Sports Medicine Authors: Anwei Liu Xiaogan Hou Jing Nie Qiang Wen Zhiguo Pan Source Type: research
Decompression sickness followed by diabetic ketoacidosis and sepsis shock: an unusual case report
Undersea Hyperb Med. 2024 First Quarter;51(1):41-46.ABSTRACTDecompression sickness (DCS) is caused by abrupt changes in extracorporeal pressure with varying severity. Symptoms range from mild musculoskeletal pain to severe organ dysfunction and death, especially among patients with chronic underlying disease. Here, we report an unusual case of a 49-year-old man who experienced DCS after a dive to a depth of 38 meters. The patient's symptoms progressed, starting with mild physical discomfort that progressed to disturbance of consciousness on the second morning. During hospitalization, we identified that in addition to DCS, ...
Source: Undersea and Hyperbaric Medicine - April 14, 2024 Category: Sports Medicine Authors: Anwei Liu Xiaogan Hou Jing Nie Qiang Wen Zhiguo Pan Source Type: research
Quercetin alleviates chronic unpredictable mild stress-induced depression-like behavior by inhibiting NMDAR1 with α2δ-1 in rats
CONCLUSIONS: Que has a good antidepressant effect and can significantly improve the depression-like behavior caused by CUMS. It exerts antidepressant effects by inhibiting the expression level of α2δ-1, interfering with the interaction between α2δ-1 and NMDAR, and then reducing the excitability of the HPA axis.PMID:38615365 | PMC:PMC11016343 | DOI:10.1111/cns.14724 (Source: CNS Neuroscience and Therapeutics)
Source: CNS Neuroscience and Therapeutics - April 14, 2024 Category: Neuroscience Authors: Mingyan Wang Xin Wei Yugai Jia Chaonan Wang Xinliu Wang Xin Zhang Depei Li Yuanyuan Wang Yonggang Gao Source Type: research
Decompression sickness followed by diabetic ketoacidosis and sepsis shock: an unusual case report
Undersea Hyperb Med. 2024 First Quarter;51(1):41-46.ABSTRACTDecompression sickness (DCS) is caused by abrupt changes in extracorporeal pressure with varying severity. Symptoms range from mild musculoskeletal pain to severe organ dysfunction and death, especially among patients with chronic underlying disease. Here, we report an unusual case of a 49-year-old man who experienced DCS after a dive to a depth of 38 meters. The patient's symptoms progressed, starting with mild physical discomfort that progressed to disturbance of consciousness on the second morning. During hospitalization, we identified that in addition to DCS, ...
Source: Undersea and Hyperbaric Medicine - April 14, 2024 Category: Sports Medicine Authors: Anwei Liu Xiaogan Hou Jing Nie Qiang Wen Zhiguo Pan Source Type: research
Quercetin alleviates chronic unpredictable mild stress-induced depression-like behavior by inhibiting NMDAR1 with α2δ-1 in rats
CONCLUSIONS: Que has a good antidepressant effect and can significantly improve the depression-like behavior caused by CUMS. It exerts antidepressant effects by inhibiting the expression level of α2δ-1, interfering with the interaction between α2δ-1 and NMDAR, and then reducing the excitability of the HPA axis.PMID:38615365 | PMC:PMC11016343 | DOI:10.1111/cns.14724 (Source: CNS Neuroscience and Therapeutics)
Source: CNS Neuroscience and Therapeutics - April 14, 2024 Category: Neuroscience Authors: Mingyan Wang Xin Wei Yugai Jia Chaonan Wang Xinliu Wang Xin Zhang Depei Li Yuanyuan Wang Yonggang Gao Source Type: research
Decompression sickness followed by diabetic ketoacidosis and sepsis shock: an unusual case report
Undersea Hyperb Med. 2024 First Quarter;51(1):41-46.ABSTRACTDecompression sickness (DCS) is caused by abrupt changes in extracorporeal pressure with varying severity. Symptoms range from mild musculoskeletal pain to severe organ dysfunction and death, especially among patients with chronic underlying disease. Here, we report an unusual case of a 49-year-old man who experienced DCS after a dive to a depth of 38 meters. The patient's symptoms progressed, starting with mild physical discomfort that progressed to disturbance of consciousness on the second morning. During hospitalization, we identified that in addition to DCS, ...
Source: Undersea and Hyperbaric Medicine - April 14, 2024 Category: Sports Medicine Authors: Anwei Liu Xiaogan Hou Jing Nie Qiang Wen Zhiguo Pan Source Type: research
The association of caffeine and nandrolone decanoate modulates aversive memory and nociception in rats
In this study, we aimed to investigate the long-term effects of ND and caffeine, either alone or in combination, on passive avoidance memory and nociception. We used the step-down and hot-plate tasks in male and female Lister Hooded rats. Our results confirmed the antinociceptive effect of caffeine and indicated that chronic administration of the ND-caffeine association promotes the evocation of aversive memory in female rats.PMID:38615923 | DOI:10.1016/j.brainres.2024.148937 (Source: Brain Research)
Source: Brain Research - April 14, 2024 Category: Neurology Authors: Daniel Bussinger de Souza Penna Samara Gumi éro Costa Alexandre Dos Santos-Rodrigues Pablo Pandolfo Source Type: research
Impact of Shared Decision-Making on Opioid Prescribing Among Patients with Chronic Pain: A Retrospective Cohort Study
This study measured whether SDM affects opioid prescribing frequency for chronic low back pain. A retrospective cohort study involving 1478 participants was conducted within a national pain research registry. The patient participation and patient orientation (PPPO) scale of the Communication Behavior Questionnaire was used to measure SDM, including classification of greater SDM (PPPO scale score≥80) or lesser SDM (PPPO scale score<80). Opioid prescribing frequency was measured at quarterly intervals from enrollment through 12 months. Baseline and longitudinal covariates were collected to adjust for potential confoundi...
Source: Pain Physician - April 14, 2024 Category: Anesthesiology Authors: John C Licciardone Braden Van Alfen Michaela N Digilio Rylan Fowers Bassam Ballout Yasser Bibi Subhash Aryal Source Type: research
Quercetin alleviates chronic unpredictable mild stress-induced depression-like behavior by inhibiting NMDAR1 with α2δ-1 in rats
CONCLUSIONS: Que has a good antidepressant effect and can significantly improve the depression-like behavior caused by CUMS. It exerts antidepressant effects by inhibiting the expression level of α2δ-1, interfering with the interaction between α2δ-1 and NMDAR, and then reducing the excitability of the HPA axis.PMID:38615365 | PMC:PMC11016343 | DOI:10.1111/cns.14724 (Source: CNS Neuroscience and Therapeutics)
Source: CNS Neuroscience and Therapeutics - April 14, 2024 Category: Neuroscience Authors: Mingyan Wang Xin Wei Yugai Jia Chaonan Wang Xinliu Wang Xin Zhang Depei Li Yuanyuan Wang Yonggang Gao Source Type: research
The association of caffeine and nandrolone decanoate modulates aversive memory and nociception in rats
In this study, we aimed to investigate the long-term effects of ND and caffeine, either alone or in combination, on passive avoidance memory and nociception. We used the step-down and hot-plate tasks in male and female Lister Hooded rats. Our results confirmed the antinociceptive effect of caffeine and indicated that chronic administration of the ND-caffeine association promotes the evocation of aversive memory in female rats.PMID:38615923 | DOI:10.1016/j.brainres.2024.148937 (Source: Brain Research)
Source: Brain Research - April 14, 2024 Category: Neurology Authors: Daniel Bussinger de Souza Penna Samara Gumi éro Costa Alexandre Dos Santos-Rodrigues Pablo Pandolfo Source Type: research
Impact of Shared Decision-Making on Opioid Prescribing Among Patients with Chronic Pain: A Retrospective Cohort Study
This study measured whether SDM affects opioid prescribing frequency for chronic low back pain. A retrospective cohort study involving 1478 participants was conducted within a national pain research registry. The patient participation and patient orientation (PPPO) scale of the Communication Behavior Questionnaire was used to measure SDM, including classification of greater SDM (PPPO scale score≥80) or lesser SDM (PPPO scale score<80). Opioid prescribing frequency was measured at quarterly intervals from enrollment through 12 months. Baseline and longitudinal covariates were collected to adjust for potential confoundi...
Source: Pain Physician - April 14, 2024 Category: Anesthesiology Authors: John C Licciardone Braden Van Alfen Michaela N Digilio Rylan Fowers Bassam Ballout Yasser Bibi Subhash Aryal Source Type: research
Evaluation of the thickness of the transverse muscles of the abdomen and the internal oblique muscles using ultrasound imaging in women with back pain
It has been estimated that chronic low back pain (LBP) affects 18% of young people, and 28-42% of people in middle age, with women being more affected than men. Chronic LBP can arise from a variety of factors, among which are biomechanical changes in core muscles, such as in their thickness, which can impair spinal stability. (Source: Journal of Bodywork and Movement Therapies)
Source: Journal of Bodywork and Movement Therapies - April 14, 2024 Category: Physiotherapy Authors: Priscila Kalil Morelh ão, Viviane Akemi Kakazu, Ygor Matos Luciano, Crystian Bitencourt Soares Oliveira, Rafael Zambelli Pinto, Cynthia Gobbi, Paulo Fernandes Pires, Fabrício José Jassi Source Type: research
Quantitative measurement of dural ectasia: associations with clinical and genetic characteristics in Marfan syndrome
ConclusionOur study shed further light on the relationship between genotype, dural pathology, and the overall clinical spectrum of MFS. The identification of protein-truncating variants and those impacting cysteine content may therefore suggest closer patient monitoring, in order to address potential complications associated with DE. (Source: European Spine Journal)
Source: European Spine Journal - April 14, 2024 Category: Orthopaedics Source Type: research
Claustrum projections to the anterior cingulate modulate nociceptive and pain-associated behavior
In this study, we sought to define claustrum function in acute and chronic pain. We found enhanced claustrum activity after a painful stimulus that was attenuated in chronic inflammatory pain. Selective inhibition of claustrocingulate projection neurons enhanced acute nociception but blocked pain learning. Inversely, chemogenetic activation of claustrocingulate neurons had no effect on basal nociception but rescued inflammation-induced mechanical allodynia. Together, these results suggest that claustrocingulate neurons are a critical component of the pain neuromatrix, and dysregulation of this connection may contribute to ...
Source: Current Biology - April 13, 2024 Category: Biology Authors: Christian A Faig Gloria H K Kim Alison D Do Zo ë Dworsky-Fried Jesse Jackson Anna M W Taylor Source Type: research
Pathological claustrum activity drives aberrant cognitive network processing in human chronic pain
Curr Biol. 2024 Apr 8:S0960-9822(24)00318-X. doi: 10.1016/j.cub.2024.03.021. Online ahead of print.ABSTRACTAberrant cognitive network activity and cognitive deficits are established features of chronic pain. However, the nature of cognitive network alterations associated with chronic pain and their underlying mechanisms require elucidation. Here, we report that the claustrum, a subcortical nucleus implicated in cognitive network modulation, is activated by acute painful stimulation and pain-predictive cues in healthy participants. Moreover, we discover pathological activity of the claustrum and a region near the posterior ...
Source: Current Biology - April 13, 2024 Category: Biology Authors: Brent W Stewart Michael L Keaser Hwiyoung Lee Sarah M Margerison Matthew A Cormie Massieh Moayedi Martin A Lindquist Shuo Chen Brian N Mathur David A Seminowicz Source Type: research
