The association of caffeine and nandrolone decanoate modulates aversive memory and nociception in rats

In this study, we aimed to investigate the long-term effects of ND and caffeine, either alone or in combination, on passive avoidance memory and nociception. We used the step-down and hot-plate tasks in male and female Lister Hooded rats. Our results confirmed the antinociceptive effect of caffeine and indicated that chronic administration of the ND-caffeine association promotes the evocation of aversive memory in female rats.PMID:38615923 | DOI:10.1016/j.brainres.2024.148937
Source: Brain Research - Category: Neurology Authors: Source Type: research