The Value of Video Rasterstereography in the Detection of Alterations in Posture as a Marker of Pain Relief after Targeted Infiltrations of the Lumbar Spine.
Conclusions from that method have so far been based on individual statements of pain relief. The main principle for the infiltrations is the assumption that by locally administering an analgesic agent to possible surgical target areas, the effect of surgery can be temporarily simulated. The aim was to investigate the use of rasterstereographic posture measurements to substantiate reported pain reduction after infiltrations. METHODS: In this case-control study (Level II), rasterstereography was performed on 57 patients and 28 reference subjects to evaluate changes in posture during 1 week of injections under fluoroscopi...
Source: Zeitschrift fur Orthopadie und Unfallchirurgie - May 22, 2020 Category: Orthopaedics Tags: Z Orthop Unfall Source Type: research

[Inflammation in Dry Eye Disease - Information on Diagnostic Testing and Therapy Using the Scientific Online Information Platform].
Authors: Knop E, Knop N Abstract Dry eye is considered the most common disease in ophthalmology. In recent decades, there has been intensive clinical and experimental research on this condition and our scientific knowledge of its pathophysiology has greatly expanded. The disease may be simple or severe and may lead to complex deregulation of the functional anatomy of the ocular surface, typically with a disparity between the clinical findings and the patient's symptoms. Chronic tissue injury induces various vicious circles that together lead to progressive worsening of the clinical picture. This can trigger inflamm...
Source: Klinische Monatsblatter fur Augenheilkunde - May 22, 2020 Category: Opthalmology Tags: Klin Monbl Augenheilkd Source Type: research

Chronic Reducible Scapholunate Ligament Dissociation: A Simple Surgical Technique for a Complex Injury
Conclusions: Chronic reducible SL dissociation can be treated affectively with SL chonderectomy, temporary SL stabilization, and ECRL tenodesis to scaphoid to restore radiologic anatomy without compromising strength or work status. Level of Evidence: Therapeutic type IV. (Source: Techniques in Hand and Upper Extremity Surgery)
Source: Techniques in Hand and Upper Extremity Surgery - May 22, 2020 Category: Surgery Tags: Techniques Source Type: research

IJERPH, Vol. 17, Pages 3643: Foot Health Status Questionnaire (FHSQ) in Spanish People with Type 2 Diabetes Mellitus: Preliminary Values Study
Conclusions: this research gives us preliminary values of the FHSQ in Spanish patients with T2DM and divided by gender, age, diabetes control, BMI, and years of diagnosis in people with T2DM. (Source: International Journal of Environmental Research and Public Health)
Source: International Journal of Environmental Research and Public Health - May 22, 2020 Category: Environmental Health Authors: Francisco Javier Dom ínguez-Muñoz Miguel Angel Garcia-Gordillo Rodrigo Anibal Diaz-Torres Miguel Ángel Hernandez-Mocholi Santos Villafaina Daniel Collado-Mateo Carmen Jim énez-Fernández Dimas Igual-Fraile Fernando P érez-Escanilla Giovanna Mart ín- Tags: Article Source Type: research

Management Strategies for Spinal Cord Injury Pain Updated for the Twenty-First Century
This article reviews selected treatment strategies for SCI-associated neuropathic pain. (Source: Physical Medicine and Rehabilitation Clinics of North America)
Source: Physical Medicine and Rehabilitation Clinics of North America - May 22, 2020 Category: Rehabilitation Authors: Erik Shaw, Michael Saulino Source Type: research

Predictors of fear-avoidance belief, pain, and disability index in patients with chronic low back pain attending rheumatology outpatient clinics
This study aimed to determine the predictors of fear-avoidance beliefs, pain, and disability indices in patients with chronic low back pain (LBP).Subjects and MethodsA cross-sectional study was carried out on patients with chronic LBP attending the rheumatology outpatient clinics at Suez Canal University Hospital. Convenience sampling was used, and the main outcome measures were fear-avoidance beliefs, pain, and disability indices, which were measured using structured questionnaires.ResultsMean age was 47  ± 13.4 years; mean body mass index (BMI) was 30.4 ± 5.47. Mean scores of the...
Source: Journal of Public Health - May 22, 2020 Category: Health Management Source Type: research

Brodie's abscess of the calcaneus in an adult patient.
This study presents a rare case of a Brodie's abscess of the calcaneus caused by Staphylococcus aureus in an adult patient. A 46-year-old immunocompetent man had undergone nonsurgical treatment since childhood owing to the diagnosis of a heel spur. Radiological evaluation revealed a benign radiolucent cystic lesion of the calcaneus surrounded by a sclerotic rim. This condition was accompanied by perilesional bone marrow edema. Thereafter, surgical treatment was planned. During surgery, the content of the lesion was observed to be purulent. Meticulous intralesional debridement was performed, and antibiotic-loaded bone cemen...
Source: Acta Orthopaedica et Traumatologica Turcica - May 22, 2020 Category: Orthopaedics Authors: Özbek EA, Başarır K, Yıldız HY Tags: Acta Orthop Traumatol Turc Source Type: research

Adjudication of cardiovascular events in patients with chronic obstructive pulmonary disease: SUMMIT trial.
CONCLUSION: A Clinical Endpoint Committee is useful for adjudication of major adverse cardiovascular events in chronic obstructive pulmonary disease trials but requires considerable resources and effort by investigators. This process can be streamlined by reviewing only serious adverse events and filtering by selected Medical Dictionary for Regulatory Activities terms. PMID: 32441114 [PubMed - as supplied by publisher] (Source: Clinical Trials)
Source: Clinical Trials - May 22, 2020 Category: Research Authors: Wise RA, Anderson JA, Amarenco P, Cowans NJ, Crim C, Denvir MA, Gomez CR, Jones MP, Morris A, Niewoehner D, Yates JC Tags: Clin Trials Source Type: research

Recurrent Aphthous Stomatitis.
ero R Abstract Recurrent aphthous stomatitis is a chronic inflammatory disease of the oral mucosa. It is characterized by painful mouth ulcers that cannot be explained by an underlying disease. Recurrent oral mucosal ulcers require a proper differential diagnosis to rule out other possible causes before recurrent aphthous stomatitis is diagnosed. The condition is common, with prevalence rates ranging from 5 to 60% in different series. Its pathogenesis is unknown, but multiple factors are considered to play a part. There are no standardized treatments for this condition and none of the treatments are curative. The ...
Source: Actas Dermo-Sifiliograficas - May 22, 2020 Category: Dermatology Authors: Sánchez J, Conejero C, Conejero R Tags: Actas Dermosifiliogr Source Type: research

Evaluation and Treatment of Primary Headaches in Adolescents.
Abstract Headache is a common episodic and chronic pain syndrome in adolescents. Evaluation of headaches in primary care requires a comprehensive assessment including lifestyle behaviors and physical examination, as well as an understanding of when to pursue appropriate testing. Primary headache disorders seen in adolescents include migraine and tension-type headache. Pharmacologic management for primary headache includes both acute and prophylactic treatment strategies. PMID: 32423712 [PubMed - in process] (Source: Primary Care)
Source: Primary Care - May 21, 2020 Category: Primary Care Authors: Walter SM, Banvard-Fox C, Cundiff C Tags: Prim Care Source Type: research

10  kHz Spinal Cord Stimulation for Combined Alleviation of Post-Laminectomy Syndrome and Chronic Abdominal Pain: A Case Report.
We describe the use of high-frequency SCS to alleviate the patient's post-laminectomy pain as well as his abdominal pain. Our case describes SCS use with multi-level lead placement targeting both post-laminectomy pain and abdominal pain. We describe a strategy that can be useful to patients with concurrent pain from more than one source. Our case also adds to the growing evidence supporting the use of SCS for treating chronic visceral pain syndromes. PMID: 32431535 [PubMed] (Source: Pain Physician)
Source: Pain Physician - May 21, 2020 Category: Anesthesiology Authors: Berger AA, Hasoon J, Urits I, Viswanath O, Gill J Tags: J Pain Res Source Type: research

Low-dose interleukin-2 reverses behavioral sensitization in multiple mouse models of headache disorders
Headache disorders are highly prevalent and debilitating, with limited treatment options. Previous studies indicate that many proinflammatory immune cells contribute to headache pathophysiology. Given the well-recognized role of regulatory T (Treg) cells in maintaining immune homeostasis, we hypothesized that enhancing Treg function may be effective to treat multiple headache disorders. In a mouse model of chronic migraine, we observed that repeated nitroglycerin (NTG, a reliable trigger of migraine in patients) administration doubled the number of CD3+ T cells in the trigeminal ganglia without altering the number of Treg ...
Source: Pain - May 21, 2020 Category: Anesthesiology Tags: Research Paper Source Type: research

Fear, boldness, and caution: parent effects on how children manage chronic pain
No abstract available (Source: Pain)
Source: Pain - May 21, 2020 Category: Anesthesiology Tags: Commentary Source Type: research

Taxonomies for chronic visceral pain
No abstract available (Source: Pain)
Source: Pain - May 21, 2020 Category: Anesthesiology Tags: Topical Review Source Type: research

My body is not working right: a cognitive behavioral model of body image and chronic pain
No abstract available (Source: Pain)
Source: Pain - May 21, 2020 Category: Anesthesiology Tags: Topical Review Source Type: research

Positive affect and chronic pain: a preregistered systematic review and meta-analysis
Chronic noncancer pain (CNCP) is a significant health burden among adults. Standard behavioral therapies typically focus on targeting negative affect (NA) and yield only modest treatment effects. The aims of this study were to systematically review and investigate the association between positive affect (PA) and pain severity among adults with CNCP. Databases that were searched included MEDLINE (PubMed), PsycINFO, CINAHL, ProQuest Dissertations and Theses, OLASTER, Open Grey, and PsyArXiv (inception to July 23, 2019). We analyzed studies that: (1) used observational, experimental, or intervention study designs; (2) enrolle...
Source: Pain - May 21, 2020 Category: Anesthesiology Tags: Systematic Review and Meta-Analysis Source Type: research

A review of the incidence and risk factors for fibromyalgia and chronic widespread pain in population-based studies
This review identified prospective cohort studies in the general population, which showed incidence (23 papers) and risk factors (37 papers) for fibromyalgia and chronic widespread pain. Median incidence of physician diagnosed fibromyalgia in the general population was 4.3 per 1000 person-years (range = 0.33-18.8) but 14.0 (1.2-32.7) if medical illness was present. Median incidence of chronic widespread pain was 12.5 per 1000 person-years (7.2-81.6) but 67 per 1000 person years (14.8-124) for those with pre-existing pain. Risk factors included various childhood difficulties, female sex (except with pre-existing medical dis...
Source: Pain - May 21, 2020 Category: Anesthesiology Tags: Comprehensive Review Source Type: research

Parent physical and mental health contributions to interpersonal fear avoidance processes in pediatric chronic pain
This study is the first to test interpersonal fear avoidance processes as possible mechanisms through which parent health (mental and physical) influences pediatric chronic pain functioning. We used structural equation models to test such an integrative model using cross-sectional data from a large clinical registry of 448 dyads of patients aged between 8 and 18 years (M = 14.57 years; SD = 2.38; 327 females) with mixed chronic pain and their parents (403 mothers). As expected, poorer parent global health was indirectly related to greater child pain interference through higher parent pain catastrophizing, and then through ...
Source: Pain - May 21, 2020 Category: Anesthesiology Tags: Research Paper Source Type: research

Does experimentally induced pain-related fear influence central and peripheral movement preparation in healthy people and patients with low back pain?
Nonspecific chronic low back pain (CLBP) is a multifactorial disorder. Pain-related fear and altered movement preparation are considered to be key factors in the chronification process. Interactions between both have been hypothesized, but studies examining the influence of situational fear on movement preparation in low back pain (LBP) are wanting, as well as studies differentiating between recurrent LBP (RLBP) and CLBP. Therefore, this study examined whether experimentally induced pain-related fear influences movement preparation. In healthy controls (n = 32), RLBP (n = 31) and CLBP (n = 30) patients central and peripher...
Source: Pain - May 21, 2020 Category: Anesthesiology Tags: Research Paper Source Type: research

Dysmenorrhea subtypes exhibit differential quantitative sensory assessment profiles
Women who develop bladder pain syndrome (BPS), irritable bowel syndrome, or dyspareunia frequently have an antecedent history of dysmenorrhea. Despite the high prevalence of menstrual pain, its role in chronic pelvic pain emergence remains understudied. We systematically characterized bladder, body, and vaginal mechanical sensitivity with quantitative sensory testing in women with dysmenorrhea (DYS, n = 147), healthy controls (HCs) (n = 37), and women with BPS (n = 25). Previously, we have shown that a noninvasive, bladder-filling task identified a subset of women with both dysmenorrhea and silent bladder pain hypersensiti...
Source: Pain - May 21, 2020 Category: Anesthesiology Tags: Research Paper Source Type: research

Brain perfusion patterns are altered in chronic knee pain: a spatial covariance analysis of arterial spin labelling MRI
Chronic musculoskeletal pain is a common problem globally. Current evidence suggests that maladapted central pain pathways are associated with pain chronicity, for example, in postoperative pain after knee replacement. Other factors such as low mood, anxiety, and tendency to catastrophize are also important contributors. We aimed to investigate brain imaging features that underpin pain chronicity based on multivariate pattern analysis of cerebral blood flow (CBF), as a marker of maladaptive brain changes. This was achieved by identifying CBF patterns that discriminate chronic pain from pain-free conditions and by exploring...
Source: Pain - May 21, 2020 Category: Anesthesiology Tags: Research Paper Source Type: research

Intergroup anxiety in pain care: impact on treatment recommendations made by white providers for black patients
This study provides important new information about intrapersonal and interpersonal contributors to race disparities in chronic pain care. These findings suggest that intergroup anxiety and the resulting situational discomfort encroach on the clinical decision-making process by influencing white providers' decisions about which pain treatments to recommend to black patients. Should these findings be replicated in future studies, they would support interventions to help providers become more aware of their trait-level intergroup anxiety and manage their state-level reactions to patients who are racially/ethnically different...
Source: Pain - May 21, 2020 Category: Anesthesiology Tags: Research Paper Source Type: research

Musculoskeletal pain in 6-year-old children: the Generation R Study
Musculoskeletal (MSK) pain is frequently reported among adolescents and children and is a common reason for consultation in primary care. Our aim is to examine its prevalence in 6-year-old children in a general population and to assess associations with physical and psychosocial factors. Data from the Generation R Study, a population-based cohort, was used. Prevalence and characteristics of MSK pain were assessed with parent-reported questionnaires at 6 years of age (N = 6200). Demographics and data on physical activity, sedentary behaviors, previous reported MSK pain, and behavioral problems were extracted from questionna...
Source: Pain - May 21, 2020 Category: Anesthesiology Tags: Research Paper Source Type: research

Nonsurgical mouse model of endometriosis-associated pain that responds to clinically active drugs
In conclusion, we have established a model of endometriosis-associated pain that responds to clinically active drugs and can, therefore, be used to identify novel therapies. (Source: Pain)
Source: Pain - May 21, 2020 Category: Anesthesiology Tags: Research Paper Source Type: research

Outcomes of prescription opioid dose escalation for chronic pain: results from a prospective cohort study
This study examined potential benefits and harms associated with prescription opioid dose escalation. Participants from 2 institutions were enrolled in a 2-year prospective cohort study. All participants (n = 517) had a musculoskeletal pain diagnosis and were receiving a stable dose of long-term opioid therapy at baseline. Participants completed self-report measures of pain, disability, depression, and potential adverse effects at baseline and every 6 months for 2 years. We reviewed electronic health record data weekly to identify episodes of prescription opioid dose escalation; participants who had increases in their dose...
Source: Pain - May 21, 2020 Category: Anesthesiology Tags: Research Paper Source Type: research

A randomized placebo-controlled trial of desipramine, cognitive behavioral therapy, and active placebo therapy for low back pain
This clinical trial evaluated the independent and combined effects of a tricyclic antidepressant (desipramine) and cognitive behavioral therapy (CBT) for chronic back pain relative to an active placebo treatment. Participants (n = 142) were patients experiencing daily chronic back pain at an intensity of ≥4/10 who were randomized to a single-center, double-blind, 12-week, 4-arm, parallel groups controlled clinical trial of (1) low concentration desipramine titrated to reach a serum concentration level of 15 to 65 ng/mL; (2) CBT and active placebo medication (benztropine mesylate, 0.125 mg); (3) low concentration desipra...
Source: Pain - May 21, 2020 Category: Anesthesiology Tags: Research Paper Source Type: research

Bodily changes and sensory sensitivity in complex regional pain syndrome and fibromyalgia
Complex regional pain syndrome (CRPS) and fibromyalgia are chronic pain conditions of unexplained origins. In addition to symptoms in the diagnostic criteria, patients can report changes to vision and other sensations or bodily functions. It is unclear whether these are greater than would be expected due to normal ageing, living with chronic pain generally, or common comorbidities of chronic pain such as depression or anxiety. We administered an on-line survey evaluating the frequencies and types of self-reported somatic symptoms, bodily changes, and sensory sensitivity in respondents with CRPS (n = 390), fibromyalgia (n =...
Source: Pain - May 21, 2020 Category: Anesthesiology Tags: Research Paper Source Type: research

Brain networks and endogenous pain inhibition are modulated by age and sex in healthy rats
Endogenous pain inhibition is less efficient in chronic pain patients. Diffuse noxious inhibitory control (DNIC), a form of endogenous pain inhibition, is compromised in women and older people, making them more vulnerable to chronic pain. However, the underlying mechanisms remain unclear. Here, we used a capsaicin-induced DNIC test and resting-state functional MRI to investigate the impact of aging and sex on endogenous pain inhibition and associated brain circuitries in healthy rats. We found that DNIC was less efficient in young females compared with young males. Diffuse noxious inhibitory control response was lost in ol...
Source: Pain - May 21, 2020 Category: Anesthesiology Tags: Research Paper Source Type: research

A systematic review on persistent trigeminal artery, in searching for a therapeutic solution to idiopathic and unresponsive trigeminal nerve inflammations and migraines.
Authors: DENTAL SUPPLEMENT, Gargiulo Isacco C, Ballini A, Paduanelli G, Nguyen KCD, Schiffman M, Aityan SK, Tapparo O, Khoa N, Dipalma G, Inchingolo F, Tran TC Abstract The rarely diagnosed persistent trigeminal artery (PTA) originates from the posterior bend or lateral wall of the intracavernous carotid artery and is the most common occurring type of remnant primitive fetal arteries. Even if PTA is uncommon, information and awareness about it could be of great help for clinicians dealing with cranial vascular imaging and operating this region. In addition, it could give a supporting response to the presence of a w...
Source: Journal of Biological Regulators and Homeostatic Agents - May 21, 2020 Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research

Reduced chronic pain: Another benefit of recovery at an inpatient rehabilitation facility over a skilled nursing facility?
Publication date: Available online 19 May 2020Source: The American Journal of SurgeryAuthor(s): Juan P. Herrera-Escobar, David Blake, Alexander Toppo, Kelsey Han, George Kasotakis, Haytham MA. Kaafarani, George Velmahos, Adil H. Haider, Ali Salim, Deepika Nehra (Source: The American Journal of Surgery)
Source: The American Journal of Surgery - May 21, 2020 Category: Surgery Source Type: research

Sprains, Strains, and Partial Tears of the Medial Ulnar Collateral Ligament of the Elbow
Medial ulnar collateral ligament (MUCL) insufficiency is becoming common in younger, nonprofessional athletes. In contrast to elite athletes who develop valgus extension overload syndrome and associated chronic pathologic changes in the MUCL, younger patients present with sprains and partial tears that can often be managed non-operatively with successful outcome and rapid return to play. In the younger throwing athlete with medial-sided elbow pain, a hinged elbow brace and rehabilitation of dysfunctional muscles often lead to successful recovery and return to play within 1-2 months. In more severe injuries, direct repair o...
Source: Clinics in Sports Medicine - May 21, 2020 Category: Sports Medicine Authors: Felix H. Savoie, Michael O ’Brien Source Type: research

A Crack in the Wall: Chronic Pain Management in Integrative Group Medical Visits
Publication date: Available online 20 May 2020Source: Social Science & MedicineAuthor(s): Ariana Thompson-Lastad, Sara Rubin (Source: Social Science and Medicine)
Source: Social Science and Medicine - May 21, 2020 Category: Psychiatry & Psychology Source Type: research

Diagnosing peripheral neuropathy in South ‐East Asia: A focus on diabetic neuropathy
Diabetic neuropathy has a major impact on morbidity and mortality. However, the diagnosis and management of diabetic neuropathy is South ‐East Asia is limited. Clear guidance is required to diagnose and manage patients with diabetic and other neuropathies. AbstractBurning and stabbing pain in the feet and lower limbs can have a significant impact on the activities of daily living, including walking, climbing stairs and sleeping. Peripheral neuropathy in particular is often misdiagnosed or underdiagnosed because of a lack of awareness amongst both patients and physicians. Furthermore, crude screening tools, such as the 10...
Source: Journal of Diabetes Investigation - May 21, 2020 Category: Endocrinology Authors: Rayaz A Malik, Aimee Andag ‐Silva, Charungthai Dejthevaporn, Manfaluthy Hakim, Jasmine S Koh, Rizaldy Pinzon, Norlela Sukor, Ka Sing Wong Tags: Review Article Source Type: research

IJERPH, Vol. 17, Pages 3634: Low-Intensity Physical Exercise Improves Pain Catastrophizing and Other Psychological and Physical Aspects in Women with Fibromyalgia: A Randomized Controlled Trial
In conclusion, a low-intensity combined PE program, including endurance training and coordination, improves psychological variables, pain perception, quality of life, and physical conditioning in women with FM. (Source: International Journal of Environmental Research and Public Health)
Source: International Journal of Environmental Research and Public Health - May 21, 2020 Category: Environmental Health Authors: Ruth Izquierdo-Alventosa Marta Ingl és Sara Cort és-Amador Lucia Gimeno-Mallench Javier Chirivella-Garrido Juri Kropotov Pilar Serra-A ñó Tags: Article Source Type: research

IJERPH, Vol. 17, Pages 3641: The Impact of Endometriosis on the Quality of Life and the Incidence of Depression —A Cohort Study
The objective was to evaluate the quality of life and the incidence of depression among women suffering from endometriosis. Afterwards, the dependency between pelvic pain, its severity and stages of endometriosis were analyzed. The study protocol included women of reproductive ages with confirmed endometriosis. The stage of disease was conferred according to the ASRM (American Society of Reproductive Medicine) classification. Women fulfilled two questionnaires: “WERF EPHect Clinical Questionnaire” and self-prepared survey about fertility disorders. The study group comprised of 246 respondents. A...
Source: International Journal of Environmental Research and Public Health - May 21, 2020 Category: Environmental Health Authors: Warzecha Szymusik Wielgos Pietrzak Tags: Article Source Type: research

Emergency department analgesia in patients with traumatic injuries on outpatient buprenorphine
Moderate to severe acute pain occurs in 91% of traumatic injury patients presenting to the emergency department (ED) and suboptimal analgesia is common [1-3]. Timely and adequate pain control is crucial, as inadequate management has been associated with increased morbidity and development of chronic pain, post-traumatic stress disorder, anxiety, and depression [4]. Intravenous (IV) opioids are routinely used for treatment of acute pain in trauma patients, but increasing outpatient use of buprenorphine for opioid use disorder (OUD) and chronic pain poses a new challenge to traditional pain management strategies [5]. (Source...
Source: The American Journal of Emergency Medicine - May 21, 2020 Category: Emergency Medicine Authors: Emma L. Chee-How, Nicole M. Acquisto, Jennifer Iuppa Melaragno, Kate Kokanovich, Justin Foster, Rachel F. Schult Source Type: research

A Healthcare Improvement Initiative to Increase Multidisciplinary Pain Management Referrals for Youth with Sickle Cell Disease
Chronic pain is a complex integration of biological, psychological, and social variables. Multidisciplinary pain management experts design interventions that treat the multidimensional experience. Children and adolescents with sickle cell disease (SCD) are at risk for chronic pain. Increased risk is associated with multiple characteristics including sickle cell genotype, age, gender, frequency of hospitalization, duration of hospitalization, and certain comorbid diagnoses. Referral to pain management professionals for this population is often delayed. (Source: Pain Management Nursing)
Source: Pain Management Nursing - May 21, 2020 Category: Nursing Authors: Rae Ann Kingsley Tags: Original Article Source Type: research

Ultrasound Imaging Guide for Assessment of the Intrinsic Ligaments Stabilizing the Subtalar and Midtarsal Joints
The objective of this article is twofold: to describe the relevant anatomy and biomechanics related to the ligaments that stabilize the subtalar, talocalcaneonavicular, and calcaneocuboid joints, and to illustrate reasoned landmark-based scanning techniques to provide a systematic examination of these ligaments and thus make ultrasound an effective tool for assessment of patients with suspected subtalar or midtarsal sprain. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Sem...
Source: Seminars in Musculoskeletal Radiology - May 21, 2020 Category: Radiology Authors: Zaottini, Federico Picasso, Riccardo Pistoia, Federico Perez, Maribel Miguel M öller, Ingrid Rossi, Federica Bruns, Alessandra Tagliafico, Alberto Stefano Martinoli, Carlo Tags: Review Article Source Type: research

Variations of Oral Microbiome in Chronic Insomnia Patients with Different Tongue Features.
Abstract Chronic insomnia is a disease which brings intense mental pain and disturbing complications to patients worldwide. The oral microbiome exhibits a mechanistic influence on human health. Therefore, it is crucial to understand the oral microbial diversity in insomnia. Tongue diagnosis has been considered a critical basic procedure in insomnia therapeutic decision-making in Traditional Chinese Medicine (TCM). Hence, it is significant to elucidate the various oral microbiome differences in chronic insomnia patients with different tongue features. In this paper, we used 16S rRNA gene sequencing and bioinformati...
Source: The American Journal of Chinese Medicine - May 21, 2020 Category: Complementary Medicine Authors: Liu M, Wang X, Wu F, Dai N, Chen M, Yu J, Guan J, Li F Tags: Am J Chin Med Source Type: research

Average daily itch versus worst daily itch in chronic itch evaluation.
Abstract Chronic itch can be a debilitating medical condition with clinical characteristics and impact akin to chronic pain. Itch severity is subjective and clinicians depend on patient reported numerical ratings scales (NRS); most commonly 24-hour worst itch (WI-NRS) has been validated including large scale studies. WI-NRS does not attempt to take into account itch duration or the variability that is often experienced throughout the day and night by chronic itch patients. PMID: 32438472 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - May 21, 2020 Category: Dermatology Authors: Fourzali KM, Golpanian S, Chan YH, Yosipovitch G Tags: Br J Dermatol Source Type: research

Anti-nerve growth factor antibodies for the treatment of low back pain.
Abstract INTRODUCTION: The treatment of chronic low back pain (cLBP) often involves multimodal pharmacologic and non-pharmacologic strategies. There remain shortcomings with these tools with regards to both effect size and side effects. AREAS COVERED: In an effort to better address cLBP, anti-nerve growth factor (NGF) monoclonal antibodies (mAbs) are nearing marketing approval. This class of medications has been primarily evaluated for osteoarthritis, but are being examined at higher doses for use in cLBP. We review the efficacy of this class in treating LBP as well as their potential side effects based on ni...
Source: Pharmacological Reviews - May 21, 2020 Category: Drugs & Pharmacology Authors: Patel F, Hess DK, Maher DP Tags: Expert Rev Clin Pharmacol Source Type: research

Spirituality Needs in Chronic Pain Patients: A Cross-Sectional Study in a General Hospital in Malaysia
This study aimed to explore the factors associated with spirituality needs among chronic pain patients in a general hospital in Malaysia. An analytical cross-sectional study was conducted among 117 chronic pain patients in a general hospital in Malaysia. Clinical features and assessments were evaluated by an experienced pain physician and retrieved from patient medical records. An interviewer-administered questionnaire that consisted of items on socio-demographics, the validated 19-items spiritual needs questionnaire and the visual analog scale was utilized. Multivariate linear regression analysis was conducted to identify...
Source: Journal of Religion and Health - May 20, 2020 Category: Medical Ethics Source Type: research

CBS-Induced H2S Generation in Hippocampus Inhibits EA-Induced Analgesia.
Authors: Ren WJ, Fu J, Yin HY, Xu NG, Tang CZ, Liu LZ, Yu SG, Tang Y Abstract Hydrogen sulfide (H2S) is an important mediator participating in both physiological and pathological systems and related to the inflammatory process. Acupuncture has a therapeutic effect on inflammatory pain. However, whether H2S generated in the central nervous system (CNS) is a mediator of electroacupuncture (EA) treatment for inflammatory pain is unknown. We injected complete Freund's adjuvant (CFA) to induce inflammatory pain and applied EA treatment as an interventional strategy for pain relief. The results presented here show that S...
Source: Evidence-based Complementary and Alternative Medicine - May 20, 2020 Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research

Determination of Related Factors about Diagnostic and Treatment Delays in Patients with Smear-positive Pulmonary Tuberculosis in Turkey.
CONCLUSION: In the diagnosis process of patients with tuberculosis, it was determined that there was an improvement in the patient delay; however, the improvement in diagnosis delay was still not acceptable as an ideal duration. PMID: 32421283 [PubMed - as supplied by publisher] (Source: Turkish Journal of Medical Sciences)
Source: Turkish Journal of Medical Sciences - May 20, 2020 Category: General Medicine Tags: Turk J Med Sci Source Type: research

Impaired mesocorticolimbic connectivity underlies increased mechanical pain sensitivity in chronic low back pain
Publication date: Available online 18 May 2020Source: NeuroImageAuthor(s): Siyi Yu, Wen Li, Wei Shen, Robert R. Edwards, Randy L. Gollub, Georgia Wilson, Joel Park, Ana Ortiz, Jin Cao, Jessica Gerber, Ishtiaq Mawla, Suk-Tak Chan, Jeungchan Lee, Ajay D. Wasan, Vitaly Napadow, Ted J. Kaptchuk, Bruce Rosen, Jian Kong (Source: NeuroImage)
Source: NeuroImage - May 20, 2020 Category: Neuroscience Source Type: research

Managing breakthrough pain for advanced malignancy in elderly patients: A real challenge.
We report a case morphine toxicity in an elderly patient of lung cancer with concomitant presence of chronic obstructive pulmonary disease (COPD) and recent onset renal impairment. Opioid analgesic overdose is a lethal but at the same time, a preventable and treatable condition. We managed the case using naloxone infusion. However, we emphasize early anticipation and recognition of predisposing factors followed by timely intervention to manage this life-threatening condition. PMID: 32421843 [PubMed - in process] (Source: Journal of Opioid Management)
Source: Journal of Opioid Management - May 20, 2020 Category: Addiction Tags: J Opioid Manag Source Type: research

Cannabidiol (CBD) as a treatment of acute and chronic back pain: A case series and literature review.
Conclusion: Hemp-derived CBD in a transdermal cream provided significant symptom and pain relief for the patients described in this case series. Based on these results, we believe further investigation is warranted to see if CBD-containing products should have a more prominent role in the treatment of acute and chronic pain. PMID: 32421842 [PubMed - in process] (Source: Journal of Opioid Management)
Source: Journal of Opioid Management - May 20, 2020 Category: Addiction Tags: J Opioid Manag Source Type: research

Factors associated with participation and nonparticipation in a VA Whole Health Primary Care Pain Education and Opioid Monitoring Program (PC-POP).
CONCLUSIONS: Given that primary care is the dominant healthcare setting in which opioids are prescribed for chronic noncancer pain, programs are needed to assist primary care providers to meet the rigorous requirements of guideline concordant care. The current study examined participation factors in such a program and found that certain veterans were less likely to participate than others. Identifying such veterans at the outset, in combination with intentional recruitment efforts and individualized interventions, may promote entry into PC-POP. PMID: 32421838 [PubMed - in process] (Source: Journal of Opioid Management)
Source: Journal of Opioid Management - May 20, 2020 Category: Addiction Tags: J Opioid Manag Source Type: research

Sensors, Vol. 20, Pages 2902: A Practical Sensor-Based Methodology for the Quantitative Assessment and Classification of Chronic Non Specific Low Back Patients (NSLBP) in Clinical Settings
This study aimed to classify chronic nonspecific low back pain (NSLBP) patients using our previously developed and validated wearable inertial sensor (SHARIF-HMIS) for the assessment of trunk kinematic parameters. One hundred NSLBP patients consented to perform repetitive flexural movements in five different planes of motion (PLM): 0° in the sagittal plane, as well as 15° and 30° lateral rotation to the right and left, respectively. They were divided into three subgroups based on the STarT Back Screening Tool. The sensor was placed on the trunk of each patient. An ANOVA mixed model was c...
Source: Sensors - May 20, 2020 Category: Biotechnology Authors: Mehrdad Davoudi Seyyed Mohammadreza Shokouhyan Mohsen Abedi Narges Meftahi Atefeh Rahimi Ehsan Rashedi Maryam Hoviattalab Roya Narimani Mohamad Parnianpour Kinda Khalaf Tags: Article Source Type: research

Evaluation of the effects of photobiomodulation therapy and ozone applications after gingivectomy and gingivoplasty on postoperative pain and patients ’ oral health-related quality of life
In this study, 36 patients with chronic inflammatory gingival enlargement underwent gingivectomy and gingivoplasty. The groups were randomly divided into control (n = 12), PBM (n = 12) and ozone (n = 12) groups. GaAlAs diode laser 810 nm wavelength at a non-contact and continuous mode with a power of 0.3 W and a density of 4 J/cm2 used for PBM for 1  min. Ozone was applied for 1 min for every 5 mm2 in contact mode at power level 9 using probe number 3. PBM and ozone applications were performed immediately after the operation, on the 3rd and 7th days. P...
Source: Lasers in Medical Science - May 20, 2020 Category: Laser Surgery Source Type: research