Parent physical and mental health contributions to interpersonal fear avoidance processes in pediatric chronic pain
This study is the first to test interpersonal fear avoidance processes as possible mechanisms through which parent health (mental and physical) influences pediatric chronic pain functioning. We used structural equation models to test such an integrative model using cross-sectional data from a large clinical registry of 448 dyads of patients aged between 8 and 18 years (M = 14.57 years; SD = 2.38; 327 females) with mixed chronic pain and their parents (403 mothers). As expected, poorer parent global health was indirectly related to greater child pain interference through higher parent pain catastrophizing, and then through ...
Source: Pain - May 21, 2020 Category: Anesthesiology Tags: Research Paper Source Type: research

Does experimentally induced pain-related fear influence central and peripheral movement preparation in healthy people and patients with low back pain?
Nonspecific chronic low back pain (CLBP) is a multifactorial disorder. Pain-related fear and altered movement preparation are considered to be key factors in the chronification process. Interactions between both have been hypothesized, but studies examining the influence of situational fear on movement preparation in low back pain (LBP) are wanting, as well as studies differentiating between recurrent LBP (RLBP) and CLBP. Therefore, this study examined whether experimentally induced pain-related fear influences movement preparation. In healthy controls (n = 32), RLBP (n = 31) and CLBP (n = 30) patients central and peripher...
Source: Pain - May 21, 2020 Category: Anesthesiology Tags: Research Paper Source Type: research

Dysmenorrhea subtypes exhibit differential quantitative sensory assessment profiles
Women who develop bladder pain syndrome (BPS), irritable bowel syndrome, or dyspareunia frequently have an antecedent history of dysmenorrhea. Despite the high prevalence of menstrual pain, its role in chronic pelvic pain emergence remains understudied. We systematically characterized bladder, body, and vaginal mechanical sensitivity with quantitative sensory testing in women with dysmenorrhea (DYS, n = 147), healthy controls (HCs) (n = 37), and women with BPS (n = 25). Previously, we have shown that a noninvasive, bladder-filling task identified a subset of women with both dysmenorrhea and silent bladder pain hypersensiti...
Source: Pain - May 21, 2020 Category: Anesthesiology Tags: Research Paper Source Type: research

Brain perfusion patterns are altered in chronic knee pain: a spatial covariance analysis of arterial spin labelling MRI
Chronic musculoskeletal pain is a common problem globally. Current evidence suggests that maladapted central pain pathways are associated with pain chronicity, for example, in postoperative pain after knee replacement. Other factors such as low mood, anxiety, and tendency to catastrophize are also important contributors. We aimed to investigate brain imaging features that underpin pain chronicity based on multivariate pattern analysis of cerebral blood flow (CBF), as a marker of maladaptive brain changes. This was achieved by identifying CBF patterns that discriminate chronic pain from pain-free conditions and by exploring...
Source: Pain - May 21, 2020 Category: Anesthesiology Tags: Research Paper Source Type: research

Intergroup anxiety in pain care: impact on treatment recommendations made by white providers for black patients
This study provides important new information about intrapersonal and interpersonal contributors to race disparities in chronic pain care. These findings suggest that intergroup anxiety and the resulting situational discomfort encroach on the clinical decision-making process by influencing white providers' decisions about which pain treatments to recommend to black patients. Should these findings be replicated in future studies, they would support interventions to help providers become more aware of their trait-level intergroup anxiety and manage their state-level reactions to patients who are racially/ethnically different...
Source: Pain - May 21, 2020 Category: Anesthesiology Tags: Research Paper Source Type: research

Musculoskeletal pain in 6-year-old children: the Generation R Study
Musculoskeletal (MSK) pain is frequently reported among adolescents and children and is a common reason for consultation in primary care. Our aim is to examine its prevalence in 6-year-old children in a general population and to assess associations with physical and psychosocial factors. Data from the Generation R Study, a population-based cohort, was used. Prevalence and characteristics of MSK pain were assessed with parent-reported questionnaires at 6 years of age (N = 6200). Demographics and data on physical activity, sedentary behaviors, previous reported MSK pain, and behavioral problems were extracted from questionna...
Source: Pain - May 21, 2020 Category: Anesthesiology Tags: Research Paper Source Type: research

Nonsurgical mouse model of endometriosis-associated pain that responds to clinically active drugs
In conclusion, we have established a model of endometriosis-associated pain that responds to clinically active drugs and can, therefore, be used to identify novel therapies. (Source: Pain)
Source: Pain - May 21, 2020 Category: Anesthesiology Tags: Research Paper Source Type: research

Outcomes of prescription opioid dose escalation for chronic pain: results from a prospective cohort study
This study examined potential benefits and harms associated with prescription opioid dose escalation. Participants from 2 institutions were enrolled in a 2-year prospective cohort study. All participants (n = 517) had a musculoskeletal pain diagnosis and were receiving a stable dose of long-term opioid therapy at baseline. Participants completed self-report measures of pain, disability, depression, and potential adverse effects at baseline and every 6 months for 2 years. We reviewed electronic health record data weekly to identify episodes of prescription opioid dose escalation; participants who had increases in their dose...
Source: Pain - May 21, 2020 Category: Anesthesiology Tags: Research Paper Source Type: research

A randomized placebo-controlled trial of desipramine, cognitive behavioral therapy, and active placebo therapy for low back pain
This clinical trial evaluated the independent and combined effects of a tricyclic antidepressant (desipramine) and cognitive behavioral therapy (CBT) for chronic back pain relative to an active placebo treatment. Participants (n = 142) were patients experiencing daily chronic back pain at an intensity of ≥4/10 who were randomized to a single-center, double-blind, 12-week, 4-arm, parallel groups controlled clinical trial of (1) low concentration desipramine titrated to reach a serum concentration level of 15 to 65 ng/mL; (2) CBT and active placebo medication (benztropine mesylate, 0.125 mg); (3) low concentration desipra...
Source: Pain - May 21, 2020 Category: Anesthesiology Tags: Research Paper Source Type: research

Bodily changes and sensory sensitivity in complex regional pain syndrome and fibromyalgia
Complex regional pain syndrome (CRPS) and fibromyalgia are chronic pain conditions of unexplained origins. In addition to symptoms in the diagnostic criteria, patients can report changes to vision and other sensations or bodily functions. It is unclear whether these are greater than would be expected due to normal ageing, living with chronic pain generally, or common comorbidities of chronic pain such as depression or anxiety. We administered an on-line survey evaluating the frequencies and types of self-reported somatic symptoms, bodily changes, and sensory sensitivity in respondents with CRPS (n = 390), fibromyalgia (n =...
Source: Pain - May 21, 2020 Category: Anesthesiology Tags: Research Paper Source Type: research

Brain networks and endogenous pain inhibition are modulated by age and sex in healthy rats
Endogenous pain inhibition is less efficient in chronic pain patients. Diffuse noxious inhibitory control (DNIC), a form of endogenous pain inhibition, is compromised in women and older people, making them more vulnerable to chronic pain. However, the underlying mechanisms remain unclear. Here, we used a capsaicin-induced DNIC test and resting-state functional MRI to investigate the impact of aging and sex on endogenous pain inhibition and associated brain circuitries in healthy rats. We found that DNIC was less efficient in young females compared with young males. Diffuse noxious inhibitory control response was lost in ol...
Source: Pain - May 21, 2020 Category: Anesthesiology Tags: Research Paper Source Type: research

A systematic review on persistent trigeminal artery, in searching for a therapeutic solution to idiopathic and unresponsive trigeminal nerve inflammations and migraines.
Authors: DENTAL SUPPLEMENT, Gargiulo Isacco C, Ballini A, Paduanelli G, Nguyen KCD, Schiffman M, Aityan SK, Tapparo O, Khoa N, Dipalma G, Inchingolo F, Tran TC Abstract The rarely diagnosed persistent trigeminal artery (PTA) originates from the posterior bend or lateral wall of the intracavernous carotid artery and is the most common occurring type of remnant primitive fetal arteries. Even if PTA is uncommon, information and awareness about it could be of great help for clinicians dealing with cranial vascular imaging and operating this region. In addition, it could give a supporting response to the presence of a w...
Source: Journal of Biological Regulators and Homeostatic Agents - May 21, 2020 Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research

Reduced chronic pain: Another benefit of recovery at an inpatient rehabilitation facility over a skilled nursing facility?
Publication date: Available online 19 May 2020Source: The American Journal of SurgeryAuthor(s): Juan P. Herrera-Escobar, David Blake, Alexander Toppo, Kelsey Han, George Kasotakis, Haytham MA. Kaafarani, George Velmahos, Adil H. Haider, Ali Salim, Deepika Nehra (Source: The American Journal of Surgery)
Source: The American Journal of Surgery - May 21, 2020 Category: Surgery Source Type: research

Sprains, Strains, and Partial Tears of the Medial Ulnar Collateral Ligament of the Elbow
Medial ulnar collateral ligament (MUCL) insufficiency is becoming common in younger, nonprofessional athletes. In contrast to elite athletes who develop valgus extension overload syndrome and associated chronic pathologic changes in the MUCL, younger patients present with sprains and partial tears that can often be managed non-operatively with successful outcome and rapid return to play. In the younger throwing athlete with medial-sided elbow pain, a hinged elbow brace and rehabilitation of dysfunctional muscles often lead to successful recovery and return to play within 1-2 months. In more severe injuries, direct repair o...
Source: Clinics in Sports Medicine - May 21, 2020 Category: Sports Medicine Authors: Felix H. Savoie, Michael O ’Brien Source Type: research

A Crack in the Wall: Chronic Pain Management in Integrative Group Medical Visits
Publication date: Available online 20 May 2020Source: Social Science & MedicineAuthor(s): Ariana Thompson-Lastad, Sara Rubin (Source: Social Science and Medicine)
Source: Social Science and Medicine - May 21, 2020 Category: Psychiatry & Psychology Source Type: research

Diagnosing peripheral neuropathy in South ‐East Asia: A focus on diabetic neuropathy
Diabetic neuropathy has a major impact on morbidity and mortality. However, the diagnosis and management of diabetic neuropathy is South ‐East Asia is limited. Clear guidance is required to diagnose and manage patients with diabetic and other neuropathies. AbstractBurning and stabbing pain in the feet and lower limbs can have a significant impact on the activities of daily living, including walking, climbing stairs and sleeping. Peripheral neuropathy in particular is often misdiagnosed or underdiagnosed because of a lack of awareness amongst both patients and physicians. Furthermore, crude screening tools, such as the 10...
Source: Journal of Diabetes Investigation - May 21, 2020 Category: Endocrinology Authors: Rayaz A Malik, Aimee Andag ‐Silva, Charungthai Dejthevaporn, Manfaluthy Hakim, Jasmine S Koh, Rizaldy Pinzon, Norlela Sukor, Ka Sing Wong Tags: Review Article Source Type: research

IJERPH, Vol. 17, Pages 3634: Low-Intensity Physical Exercise Improves Pain Catastrophizing and Other Psychological and Physical Aspects in Women with Fibromyalgia: A Randomized Controlled Trial
In conclusion, a low-intensity combined PE program, including endurance training and coordination, improves psychological variables, pain perception, quality of life, and physical conditioning in women with FM. (Source: International Journal of Environmental Research and Public Health)
Source: International Journal of Environmental Research and Public Health - May 21, 2020 Category: Environmental Health Authors: Ruth Izquierdo-Alventosa Marta Ingl és Sara Cort és-Amador Lucia Gimeno-Mallench Javier Chirivella-Garrido Juri Kropotov Pilar Serra-A ñó Tags: Article Source Type: research

IJERPH, Vol. 17, Pages 3641: The Impact of Endometriosis on the Quality of Life and the Incidence of Depression —A Cohort Study
The objective was to evaluate the quality of life and the incidence of depression among women suffering from endometriosis. Afterwards, the dependency between pelvic pain, its severity and stages of endometriosis were analyzed. The study protocol included women of reproductive ages with confirmed endometriosis. The stage of disease was conferred according to the ASRM (American Society of Reproductive Medicine) classification. Women fulfilled two questionnaires: “WERF EPHect Clinical Questionnaire” and self-prepared survey about fertility disorders. The study group comprised of 246 respondents. A...
Source: International Journal of Environmental Research and Public Health - May 21, 2020 Category: Environmental Health Authors: Warzecha Szymusik Wielgos Pietrzak Tags: Article Source Type: research

Emergency department analgesia in patients with traumatic injuries on outpatient buprenorphine
Moderate to severe acute pain occurs in 91% of traumatic injury patients presenting to the emergency department (ED) and suboptimal analgesia is common [1-3]. Timely and adequate pain control is crucial, as inadequate management has been associated with increased morbidity and development of chronic pain, post-traumatic stress disorder, anxiety, and depression [4]. Intravenous (IV) opioids are routinely used for treatment of acute pain in trauma patients, but increasing outpatient use of buprenorphine for opioid use disorder (OUD) and chronic pain poses a new challenge to traditional pain management strategies [5]. (Source...
Source: The American Journal of Emergency Medicine - May 21, 2020 Category: Emergency Medicine Authors: Emma L. Chee-How, Nicole M. Acquisto, Jennifer Iuppa Melaragno, Kate Kokanovich, Justin Foster, Rachel F. Schult Source Type: research

A Healthcare Improvement Initiative to Increase Multidisciplinary Pain Management Referrals for Youth with Sickle Cell Disease
Chronic pain is a complex integration of biological, psychological, and social variables. Multidisciplinary pain management experts design interventions that treat the multidimensional experience. Children and adolescents with sickle cell disease (SCD) are at risk for chronic pain. Increased risk is associated with multiple characteristics including sickle cell genotype, age, gender, frequency of hospitalization, duration of hospitalization, and certain comorbid diagnoses. Referral to pain management professionals for this population is often delayed. (Source: Pain Management Nursing)
Source: Pain Management Nursing - May 21, 2020 Category: Nursing Authors: Rae Ann Kingsley Tags: Original Article Source Type: research

Ultrasound Imaging Guide for Assessment of the Intrinsic Ligaments Stabilizing the Subtalar and Midtarsal Joints
The objective of this article is twofold: to describe the relevant anatomy and biomechanics related to the ligaments that stabilize the subtalar, talocalcaneonavicular, and calcaneocuboid joints, and to illustrate reasoned landmark-based scanning techniques to provide a systematic examination of these ligaments and thus make ultrasound an effective tool for assessment of patients with suspected subtalar or midtarsal sprain. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Sem...
Source: Seminars in Musculoskeletal Radiology - May 21, 2020 Category: Radiology Authors: Zaottini, Federico Picasso, Riccardo Pistoia, Federico Perez, Maribel Miguel M öller, Ingrid Rossi, Federica Bruns, Alessandra Tagliafico, Alberto Stefano Martinoli, Carlo Tags: Review Article Source Type: research

Variations of Oral Microbiome in Chronic Insomnia Patients with Different Tongue Features.
Abstract Chronic insomnia is a disease which brings intense mental pain and disturbing complications to patients worldwide. The oral microbiome exhibits a mechanistic influence on human health. Therefore, it is crucial to understand the oral microbial diversity in insomnia. Tongue diagnosis has been considered a critical basic procedure in insomnia therapeutic decision-making in Traditional Chinese Medicine (TCM). Hence, it is significant to elucidate the various oral microbiome differences in chronic insomnia patients with different tongue features. In this paper, we used 16S rRNA gene sequencing and bioinformati...
Source: The American Journal of Chinese Medicine - May 21, 2020 Category: Complementary Medicine Authors: Liu M, Wang X, Wu F, Dai N, Chen M, Yu J, Guan J, Li F Tags: Am J Chin Med Source Type: research

Average daily itch versus worst daily itch in chronic itch evaluation.
Abstract Chronic itch can be a debilitating medical condition with clinical characteristics and impact akin to chronic pain. Itch severity is subjective and clinicians depend on patient reported numerical ratings scales (NRS); most commonly 24-hour worst itch (WI-NRS) has been validated including large scale studies. WI-NRS does not attempt to take into account itch duration or the variability that is often experienced throughout the day and night by chronic itch patients. PMID: 32438472 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - May 21, 2020 Category: Dermatology Authors: Fourzali KM, Golpanian S, Chan YH, Yosipovitch G Tags: Br J Dermatol Source Type: research

Anti-nerve growth factor antibodies for the treatment of low back pain.
Abstract INTRODUCTION: The treatment of chronic low back pain (cLBP) often involves multimodal pharmacologic and non-pharmacologic strategies. There remain shortcomings with these tools with regards to both effect size and side effects. AREAS COVERED: In an effort to better address cLBP, anti-nerve growth factor (NGF) monoclonal antibodies (mAbs) are nearing marketing approval. This class of medications has been primarily evaluated for osteoarthritis, but are being examined at higher doses for use in cLBP. We review the efficacy of this class in treating LBP as well as their potential side effects based on ni...
Source: Pharmacological Reviews - May 21, 2020 Category: Drugs & Pharmacology Authors: Patel F, Hess DK, Maher DP Tags: Expert Rev Clin Pharmacol Source Type: research

Spirituality Needs in Chronic Pain Patients: A Cross-Sectional Study in a General Hospital in Malaysia
This study aimed to explore the factors associated with spirituality needs among chronic pain patients in a general hospital in Malaysia. An analytical cross-sectional study was conducted among 117 chronic pain patients in a general hospital in Malaysia. Clinical features and assessments were evaluated by an experienced pain physician and retrieved from patient medical records. An interviewer-administered questionnaire that consisted of items on socio-demographics, the validated 19-items spiritual needs questionnaire and the visual analog scale was utilized. Multivariate linear regression analysis was conducted to identify...
Source: Journal of Religion and Health - May 20, 2020 Category: Medical Ethics Source Type: research

CBS-Induced H2S Generation in Hippocampus Inhibits EA-Induced Analgesia.
Authors: Ren WJ, Fu J, Yin HY, Xu NG, Tang CZ, Liu LZ, Yu SG, Tang Y Abstract Hydrogen sulfide (H2S) is an important mediator participating in both physiological and pathological systems and related to the inflammatory process. Acupuncture has a therapeutic effect on inflammatory pain. However, whether H2S generated in the central nervous system (CNS) is a mediator of electroacupuncture (EA) treatment for inflammatory pain is unknown. We injected complete Freund's adjuvant (CFA) to induce inflammatory pain and applied EA treatment as an interventional strategy for pain relief. The results presented here show that S...
Source: Evidence-based Complementary and Alternative Medicine - May 20, 2020 Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research

Determination of Related Factors about Diagnostic and Treatment Delays in Patients with Smear-positive Pulmonary Tuberculosis in Turkey.
CONCLUSION: In the diagnosis process of patients with tuberculosis, it was determined that there was an improvement in the patient delay; however, the improvement in diagnosis delay was still not acceptable as an ideal duration. PMID: 32421283 [PubMed - as supplied by publisher] (Source: Turkish Journal of Medical Sciences)
Source: Turkish Journal of Medical Sciences - May 20, 2020 Category: General Medicine Tags: Turk J Med Sci Source Type: research

Impaired mesocorticolimbic connectivity underlies increased mechanical pain sensitivity in chronic low back pain
Publication date: Available online 18 May 2020Source: NeuroImageAuthor(s): Siyi Yu, Wen Li, Wei Shen, Robert R. Edwards, Randy L. Gollub, Georgia Wilson, Joel Park, Ana Ortiz, Jin Cao, Jessica Gerber, Ishtiaq Mawla, Suk-Tak Chan, Jeungchan Lee, Ajay D. Wasan, Vitaly Napadow, Ted J. Kaptchuk, Bruce Rosen, Jian Kong (Source: NeuroImage)
Source: NeuroImage - May 20, 2020 Category: Neuroscience Source Type: research

Managing breakthrough pain for advanced malignancy in elderly patients: A real challenge.
We report a case morphine toxicity in an elderly patient of lung cancer with concomitant presence of chronic obstructive pulmonary disease (COPD) and recent onset renal impairment. Opioid analgesic overdose is a lethal but at the same time, a preventable and treatable condition. We managed the case using naloxone infusion. However, we emphasize early anticipation and recognition of predisposing factors followed by timely intervention to manage this life-threatening condition. PMID: 32421843 [PubMed - in process] (Source: Journal of Opioid Management)
Source: Journal of Opioid Management - May 20, 2020 Category: Addiction Tags: J Opioid Manag Source Type: research

Cannabidiol (CBD) as a treatment of acute and chronic back pain: A case series and literature review.
Conclusion: Hemp-derived CBD in a transdermal cream provided significant symptom and pain relief for the patients described in this case series. Based on these results, we believe further investigation is warranted to see if CBD-containing products should have a more prominent role in the treatment of acute and chronic pain. PMID: 32421842 [PubMed - in process] (Source: Journal of Opioid Management)
Source: Journal of Opioid Management - May 20, 2020 Category: Addiction Tags: J Opioid Manag Source Type: research

Factors associated with participation and nonparticipation in a VA Whole Health Primary Care Pain Education and Opioid Monitoring Program (PC-POP).
CONCLUSIONS: Given that primary care is the dominant healthcare setting in which opioids are prescribed for chronic noncancer pain, programs are needed to assist primary care providers to meet the rigorous requirements of guideline concordant care. The current study examined participation factors in such a program and found that certain veterans were less likely to participate than others. Identifying such veterans at the outset, in combination with intentional recruitment efforts and individualized interventions, may promote entry into PC-POP. PMID: 32421838 [PubMed - in process] (Source: Journal of Opioid Management)
Source: Journal of Opioid Management - May 20, 2020 Category: Addiction Tags: J Opioid Manag Source Type: research

Sensors, Vol. 20, Pages 2902: A Practical Sensor-Based Methodology for the Quantitative Assessment and Classification of Chronic Non Specific Low Back Patients (NSLBP) in Clinical Settings
This study aimed to classify chronic nonspecific low back pain (NSLBP) patients using our previously developed and validated wearable inertial sensor (SHARIF-HMIS) for the assessment of trunk kinematic parameters. One hundred NSLBP patients consented to perform repetitive flexural movements in five different planes of motion (PLM): 0° in the sagittal plane, as well as 15° and 30° lateral rotation to the right and left, respectively. They were divided into three subgroups based on the STarT Back Screening Tool. The sensor was placed on the trunk of each patient. An ANOVA mixed model was c...
Source: Sensors - May 20, 2020 Category: Biotechnology Authors: Mehrdad Davoudi Seyyed Mohammadreza Shokouhyan Mohsen Abedi Narges Meftahi Atefeh Rahimi Ehsan Rashedi Maryam Hoviattalab Roya Narimani Mohamad Parnianpour Kinda Khalaf Tags: Article Source Type: research

Evaluation of the effects of photobiomodulation therapy and ozone applications after gingivectomy and gingivoplasty on postoperative pain and patients ’ oral health-related quality of life
In this study, 36 patients with chronic inflammatory gingival enlargement underwent gingivectomy and gingivoplasty. The groups were randomly divided into control (n = 12), PBM (n = 12) and ozone (n = 12) groups. GaAlAs diode laser 810 nm wavelength at a non-contact and continuous mode with a power of 0.3 W and a density of 4 J/cm2 used for PBM for 1  min. Ozone was applied for 1 min for every 5 mm2 in contact mode at power level 9 using probe number 3. PBM and ozone applications were performed immediately after the operation, on the 3rd and 7th days. P...
Source: Lasers in Medical Science - May 20, 2020 Category: Laser Surgery Source Type: research

Gaps in opioid prescription for severe breathlessness in hospitalised patients with chronic obstructive pulmonary disease or interstitial lung disease
Breathlessness is the predominant and debilitating symptom in patients with advanced chronic respiratory diseases, including COPD and ILD. The “chronic breathlessness syndrome” has recently been defined as breathlessness at rest or on exertion that leads to disability, despite optimal medical treatment (1). In addition to conventional disease-directed therapy, there is conflicting evidence suggesting (and some guidelines recommend) low -dose, oral opioids may be useful for palliating chronic severe breathlessness in ILD patients and stable outpatients with advanced COPD (2-5). (Source: Journal of Pain and Symptom Management)
Source: Journal of Pain and Symptom Management - May 20, 2020 Category: Palliative Care Authors: Xinye Chen, Darran Treanor, Brian Le, Natasha Smallwood Tags: Letter Source Type: research

Interplay between body schema, visuospatial perception and pain in patients with spinal cord injury
ConclusionThese results suggest an interplay between lower body scheme distorsions and pain in patients with spinal cord injury. (Source: European Journal of Pain)
Source: European Journal of Pain - May 20, 2020 Category: Anesthesiology Authors: Thomas Osinski, Valeria Martinez, Djamel Bensmail, Samar Hatem, Didier Bouhassira Tags: ORIGINAL ARTICLE Source Type: research

Low back pain in athletes can be controlled with acupuncture by a catecholaminergic pathway: clinical trial.
CONCLUSION: EA activates the sympathetic nervous system and induces the release of epinephrine, which could ameliorate inflammation and protect muscular tissue in addition to relieving pain. PMID: 32429680 [PubMed - as supplied by publisher] (Source: Acupuncture in Medicine : journal of the British Medical Acupuncture Society)
Source: Acupuncture in Medicine : journal of the British Medical Acupuncture Society - May 20, 2020 Category: Complementary Medicine Authors: Arriaga-Pizano L, Gómez-Jiménez DC, Flores-Mejía LA, Pérez-Cervera Y, Solórzano-Mata CJ, López-Macías C, Isibasi A, Torres-Rosas R Tags: Acupunct Med Source Type: research

Efficacy and safety of duloxetine in osteoarthritis or chronic low back pain? The tip of an iceberg!
Weng and colleagues must be commended for their attempts to clarify the benefit/harm ratio of duloxetine in osteoarthritis and chronic low back pain1. Indeed, the high number of therapeutic options available shows the state of affairs is a lottery while these frequent conditions “associated with substantial work disability, morbidity, costs, and increased mortality rates” deserve robust evidence2. However, their conclusion “Duloxetine had modest to moderate effects… with mild adverse events” claiming “future randomized controlled trials should focus on comparing duloxetine…&rdquo...
Source: Osteoarthritis and Cartilage - May 20, 2020 Category: Rheumatology Authors: A. Braillon Tags: Letter to the Editor Source Type: research

Health-Related Quality of Life Among Middle-Aged Adults With Chronic Ankle Instability, Copers, and Uninjured Controls.
Abstract CONTEXT: People with chronic ankle instability (CAI) display a lower regional and global health-related quality of life (HRQoL). Examinations of HRQoL outcomes associated with CAI have addressed younger adults, restricting our understanding of the long-term consequences of CAI. OBJECTIVE: To compare ankle regional and global HRQoL in middle-aged participants with and those without CAI. DESIGN: Cross-sectional study. SETTING: Laboratory. PATIENTS OR OTHER PARTICIPANTS: A total of 59 middle-aged volunteers, consisting of 18 with CAI (age = 50.2 ± 9.3 years), 17 who were ankle-spra...
Source: J Athl Train - May 20, 2020 Category: Sports Medicine Authors: Kosik KB, Johnson NF, Terada M, Thomas-Fenwick AC, Mattacola CG, Gribble PA Tags: J Athl Train Source Type: research

Personalizing education: The clinical reasoning processes of physiotherapists using education for the treatment of people with chronic low back pain.
Conclusion: The findings highlight how communication and interaction underpin the clinical reasoning process for using education with people who have CLBP. Participating physiotherapists explored and made sense of a person's world before tailoring their educational approach for the individual. Physiotherapists can use this paper to reflect on their practice to inform their own clinical reasoning. PMID: 32431203 [PubMed - as supplied by publisher] (Source: Physiotherapy Theory and Practice)
Source: Physiotherapy Theory and Practice - May 20, 2020 Category: Physiotherapy Authors: Horler C, Hebron C, Martyn K Tags: Physiother Theory Pract Source Type: research

[Chronic pain syndromes and other persistent functional somatic symptoms].
Abstract Somatic symptoms including pain are everyday human experiences. They usually result from a complex interaction of stimuli, interpretation and reaction, and are not necessarily proportional to structural damage. Persistent functional somatic symptoms can be associated with a significant impairment of quality of life and functioning, even without mental or somatic comorbidity. Dysfunctional experiences, expectancies and behavior, not only by patients but also by physicians, can increase the risk of chronification. From the outset, management should be graded with respect to the severity and biopsychoso...
Source: Der Nervenarzt - May 20, 2020 Category: Neurology Authors: Roenneberg C, Henningsen P, Hausteiner-Wiehle C Tags: Nervenarzt Source Type: research

ASP8477, a fatty acid amide hydrolase inhibitor, exerts analgesic effects in rat models of neuropathic and dysfunctional pain.
Abstract Exogenous cannabinoid receptor agonists are clinically effective for treating chronic pain but frequently cause side effects in the central nervous system. Fatty acid amide hydrolase (FAAH) is a primary catabolic enzyme for anandamide, an endogenous cannabinoid agonist. 3-Pyridyl 4-(phenylcarbamoyl)piperidine-1-carboxylate (ASP8477) is a potent and selective FAAH inhibitor that is orally active and able to increase the brain anandamide level and is effective in rat models of neuropathic and osteoarthritis pain without causing motor coordination deficits. In the present study, we examined the pharmacokinet...
Source: European Journal of Pharmacology - May 20, 2020 Category: Drugs & Pharmacology Authors: Kiso T, Watabiki T, Sekizawa T Tags: Eur J Pharmacol Source Type: research

Predictors of Psychological Outcomes and the Effectiveness and Experience of Psychological Interventions for Adult Women with Chronic Pelvic Pain: A Scoping Review
(Source: Journal of Pain Research)
Source: Journal of Pain Research - May 19, 2020 Category: Anesthesiology Tags: Journal of Pain Research Source Type: research

Demographic Characteristics Among Patients With Chronic Exertional Compartment Syndrome of the Lower Leg.
Authors: Rynkiewicz KM, Fry LA, DiStefano LJ Abstract Clinical Scenario: Chronic exertional compartment syndrome (CECS) is a condition related with ischemia of the body's tissue due to increases in intracompartmental pressures, which involves, among other symptoms, pain with exertion. CECS is often overlooked or misdiagnosed due to an ambiguous presentation. Diagnostic accuracy of CECS and subsequent management can be improved when contributing factors are known. Research is lacking on the type of patient most likely to experience CECS, highlighting the need for identification of common demographic characteristics ...
Source: Journal of Sport Rehabilitation - May 19, 2020 Category: Sports Medicine Tags: J Sport Rehabil Source Type: research

Proposition of standardized protocol for photodynamic therapy for vulvar lichen sclerosus.
CONCLUSION: Based on a literature review we suggest the following protocol for PDT in VLS: 5% 5-ALA as a photosensitizer applied for three hours under occlusion before irradiation at the dose of 120 J/cm2 with red light (590-760 nm) and intensity of 204 mW/cm2. PMID: 32420789 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - May 19, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

IJERPH, Vol. 17, Pages 3560: Exploring Changes in Activity Patterns in Individuals with Chronic Pain
ez Ruíz-Párraga Peters Esteve This longitudinal study explored whether activity patterns change over time in a sample of 56 individuals with chronic musculoskeletal pain over a 15-day period. Once a day, the participants recorded their level of pain intensity and the degree to which they had engaged in several specific activity patterns. Linear mixed models with random coefficients were used to investigate the rate of change in the activity patterns. Age, sex, pain intensity, and pain duration were controlled. The results show that excessive persistence was the only self-reported activity pattern...
Source: International Journal of Environmental Research and Public Health - May 19, 2020 Category: Environmental Health Authors: Serrano-Ib áñez Bendayan Ram írez-Maestre L ópez-Martínez Ru íz-Párraga Peters Esteve Tags: Article Source Type: research

Quality of life changes with duration of chronic breathlessness: a random sample of community-dwelling people
Chronic breathlessness is associated with poorer quality of life. This population study aimed to define dimensions of quality of life (QoL), and duration and dominant causes of breathlessness that most diminished QoL. (Source: Journal of Pain and Symptom Management)
Source: Journal of Pain and Symptom Management - May 19, 2020 Category: Palliative Care Authors: David C. Currow, Sungwon Chang, Eleonora Dal Grande, Diana H. Ferreira, Slavica Kochovska, Irina Kinchin, Miriam J. Johnson, Magnus Ekstrom Source Type: research

Patient safety incidents involving transdermal opioids: data from the Danish Patient Safety Database
Conclusion This study has demonstrated that the administration of transdermal opioids is challenging and may cause harm, particularly in the primary care sector. To improve patient safety, optimized systems, including guidelines on drug management and the continuing education of healthcare personnel in transdermal opioid management, are necessary. These guidelines should preferably incorporate reminders and checklists, since the omission of doses was the most reported problem. (Source: International Journal of Clinical Pharmacy)
Source: International Journal of Clinical Pharmacy - May 19, 2020 Category: Drugs & Pharmacology Source Type: research

Neurogeriatrics-a  vision for improved care and research for geriatric patients with predominating neurological disabilities.
This article discusses how neurological know-how could be integrated in academic geriatric medicine to improve care of neurogeriatric patients, to foster neurogeriatric research and training concepts and to provide innovative care concepts for geriatric patients with predominant neurological conditions and disabilities. PMID: 32430766 [PubMed - as supplied by publisher] (Source: Zeitschrift fur Gerontologie und Geriatrie)
Source: Zeitschrift fur Gerontologie und Geriatrie - May 19, 2020 Category: Geriatrics Authors: Jacobs AH, Emmert K, Baron R, Bartsch T, Bauer J, Becker C, Berg D, Bergmann P, Boetzel K, Bollheimer C, Deuschl G, Djukic M, Drey M, Durwen H, Ebersbach G, Elshehabi M, Geritz J, Gisinger C, Guennewig T, Hauptmann B, Heppner HJ, Hobert MA, Hofmann W, Hue Tags: Z Gerontol Geriatr Source Type: research

Use of Erector Spinae Plane Block in Thoracic Surgery Leads to Rapid Recovery from Anesthesia.
The objective of this study was to compare Erector Spinae Plane blocks (ESP) with intercostal blocks (ICB) as part of multi-modal analgesia in quality of postoperative pain control and preservation of pulmonary function after VATS. METHODS: A consecutive cohort of patients undergoing elective VATS were enrolled in the study and divided into the ESP and ICB block groups. Spirometry and visual analog pain scores (VAS) exams were performed to measure Forced Vital Capacity (FVC), Forced Expiratory Volume at one second (FEV1), FEV1/FVC ratio, and Forced Expiratory Flow in intervals 25% to 75% (FEF25-75). Chronic pain was a...
Source: The Annals of Thoracic Surgery - May 19, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Chaudhary O, Baribeau Y, Urits I, Sharkey A, Rashid R, Hess P, Krumm S, Fatima H, Zhang Q, Gangadharan S, Mahmood F, Matyal R Tags: Ann Thorac Surg Source Type: research

Mediators of Pain and Physical Function in Female and Male Patients with Chronic Pain
(Source: Journal of Pain Research)
Source: Journal of Pain Research - May 18, 2020 Category: Anesthesiology Tags: Journal of Pain Research Source Type: research