Physiologic and biochemical rationale for treating COVID-19 patients with hyperbaric oxygen
Undersea Hyperb Med. 2021 First-Quarter;48(1):1-12.ABSTRACTThe SARS-Cov-2 (COVID-19) pandemic remains a major worldwide public health issue. Initially, improved supportive and anti-inflammatory intervention, often employing known drugs or technologies, provided measurable improvement in management. We have recently seen advances in specific therapeutic interventions and in vaccines. Nevertheless, it will be months before most of the world's population can be vaccinated to achieve herd immunity. In the interim, hyperbaric oxygen (HBO2) treatment offers several potentially beneficial therapeutic effects. Three small publishe...
Source: Undersea and Hyperbaric Medicine - March 1, 2021 Category: Sports Medicine Authors: John J Feldmeier John P Kirby Jay C Buckey Daphne W Denham Jose S Evangelista Helen B Gelly Nicole P Harlan Ziad K Mirza Kristy L Ray Marc Robins Davut J Savaser Sandra Wainwright Nick Bird Enoch T Huang Richard E Moon Stephen R Thom Lindell K Weaver Source Type: research

Advances in the treatment of neuropathic pain with hyperbaric oxygen
Undersea Hyperb Med. 2021 First-Quarter;48(1):13-23.ABSTRACTNeuropathic pain (NPP) refers to the pain caused by primary or secondary injury or dysfunction of the peripheral or central nervous system, and usually requires multidisciplinary treatment. However, most pharmacological and non-pharmacological interventions can only temporarily and/or moderately improve pain-related symptoms, and they often produce unbearable adverse reactions or cause drug resistance. Hyperbaric oxygen (HBO2) therapy has been widely used in the clinical treatment of some diseases due to its advantages of safety, few side effects, no resistance, a...
Source: Undersea and Hyperbaric Medicine - March 1, 2021 Category: Sports Medicine Authors: Yan-Yan Zhou Rong-Rong Ren Yi Cen Wen-Wu Liu Hui Chen Source Type: research

The effect of the perfluorocarbon emulsion Oxycyte ™ in an ovine model of severe decompression illness
CONCLUSION: In this ovine model of severe DCS the intravenous PFC Oxycyte did not reduce mortality but did ameliorate spinal cord injury when used after the onset of DCS.PMID:33648030 (Source: Undersea and Hyperbaric Medicine)
Source: Undersea and Hyperbaric Medicine - March 1, 2021 Category: Sports Medicine Authors: William A Cronin Kiel Khan Aaron A Hall Michael Bodo Richard T Mahon Source Type: research

Non-invasive monitoring of carboxyhemoglobin during hyperbaric oxygen therapy
CONCLUSION: To our knowledge, this study is the first to assess LOA and demonstrate use of a non-invasive method to measure COHb during HBO2 therapy. The pulse CO-oximeter performed within the manufactures reported LOA (±6%) despite hyperbaric conditions and was unaffected by changes in pressure. However, summarized saturations reached levels above 100%.PMID:33648031 (Source: Undersea and Hyperbaric Medicine)
Source: Undersea and Hyperbaric Medicine - March 1, 2021 Category: Sports Medicine Authors: Daniel Bidstrup Frederikke Ravn Isabel Guida Smidt-Nielsen Anna Mygind Wahl Erik Christian Jansen Ole Hyldegaard Source Type: research

Seizure during hyperbaric oxygen therapy: experience at a single academic hospital in Korea
CONCLUSION: Our study revealed a similar frequency rate in terms of all indications and CO poisoning, and a slightly higher rate in AGE. Seizures were observed in patients with CO poisoning and AGE. Therefore, if clinicians plan to operate a hyperbaric center in a country like Korea, where there are several patients with acute CO poisoning, they should be prepared to handle seizures that may occur during HBO2 therapy.PMID:33648032 (Source: Undersea and Hyperbaric Medicine)
Source: Undersea and Hyperbaric Medicine - March 1, 2021 Category: Sports Medicine Authors: Chan Hee Lee Jin Guel Choi Je Seop Lee Yoonsuk Lee Hyun Kim Yoon-Seop Kim Yong Sung Cha Source Type: research

Hyperbaric oxygen therapy for hypoxic-ischemic encephalopathy in non-fatal drowning
We report a case of a 5-year-old boy admitted to the Pediatric Intensive Care Unit after a non-fatal drowning. He was transferred under mechanical ventilation and sedation, with hemodynamic instability and hypothermia. On admission he had a Glasgow Coma Score of 6. On the fifth day of admission he presented episodes of dystonia with decerebration posture, diaphoresis, tachycardia and hypertension, sometimes with identified triggers, suggesting PAISD. The episodes were difficult to control; multiple drugs were needed. Electroencephalography showed diffuse slow wave activity, and cranioencephalic magnetic resonance imaging s...
Source: Undersea and Hyperbaric Medicine - March 1, 2021 Category: Sports Medicine Authors: Andreia Fi úza Ribeiro Joana Gomes Vieira Marta Moniz Carlos Escobar Clara Abadesso Carla Amaro Diogo Cavalheiro Francisco Guerreiro Catarina Luis Pedro Nunez Source Type: research

An echo from the past: Building a Doppler repository for big data in diving research
Undersea Hyperb Med. 2021 First-Quarter;48(1):57-58.ABSTRACTDecompression sickness (DCS) remains a major operational concern for diving operations, submarine escape and high-altitude jumps. Aside from DCS symptoms, venous gas emboli (VGE) detected with ultrasound post-dive are often used as a marker of decompression stress in humans, with a specificity of 100% even though the sensitivity is poor [1]. Being non-invasive, portable and non-ionizing, ultrasound is particularly suited to regular and repeated monitoring. It could help elucidate inter- and intra-subject variability in VGE and DCS susceptibility, but analyzing the...
Source: Undersea and Hyperbaric Medicine - March 1, 2021 Category: Sports Medicine Authors: Virginie Papadopoulou Peter Lindholm Source Type: research

Ultrasound in decompression research: fundamentals, considerations, and future technologies
Undersea Hyperb Med. 2021 First-Quarter;48(1):59-72.ABSTRACTIt is widely accepted that bubbles are a necessary but insufficient condition for the development of decompression sickness. However, open questions remain regarding the precise formation and behavior of these bubbles after an ambient pressure reduction (decompression), primarily due to the inherent difficulty of directly observing this phenomenon in vivo. In decompression research, information about these bubbles after a decompression is gathered via means of ultrasound acquisitions. The ability to draw conclusions regarding decompression research using ultrasoun...
Source: Undersea and Hyperbaric Medicine - March 1, 2021 Category: Sports Medicine Authors: David Q Le Paul A Dayton Frauke Tillmans John J Freiberger Richard E Moon Petar Denoble Virginie Papadopoulou Source Type: research

A fully automated method for late ventricular diastole frame selection in post-dive echocardiography without ECG gating
In conclusion, full automation of LVD frame selection for the purpose of bubble counting in post-dive echocardiography has been established with excellent accuracy, although we caution that high quality acquisitions remain paramount in retaining high reliability.PMID:33648036 (Source: Undersea and Hyperbaric Medicine)
Source: Undersea and Hyperbaric Medicine - March 1, 2021 Category: Sports Medicine Authors: Erik Markley David Q Le Peter Germonpr é Costantino Balestra Frauke Tillmans Petar Denoble John J Freiberger Richard E Moon Paul A Dayton Virginie Papadopoulou Source Type: research

Breathing through a diving snorkel; theory and experiment of air flow resistance and cost of breathing
This study aims to model these parameters and to measure indirectly the actual increases. Further, resistances of differing designs and dimensions were assessed and recommendations were made concerning use and choice. Maximal voluntary ventilation in 12 seconds (MVV12) was measured in 19 volunteers seated on dry land with and without a classic J-type snorkel (inner diameter 20.5 mm). The extra and total resistances and costs were calculated using the MVV12 data and using estimated airways resistance extrapolated from subject's demography and spirometric literature data. MVV12 measurements with snorkel showed a minute volum...
Source: Undersea and Hyperbaric Medicine - March 1, 2021 Category: Sports Medicine Authors: N A M Schellart Source Type: research

Preventing carbon monoxide poisoning in the Hudson River Tunnel in 1921: recounting history
Undersea Hyperb Med. 2021 First-Quarter;48(1):89-96.ABSTRACTThe New York Bridge and Tunnel Commission began planning for a tunnel beneath the lower Hudson river to connect Manhattan to New Jersey in 1919. At 8,300 feet, it would be the longest tunnel for passenger vehicles in the world. A team of engineers and physiologists at the Yale University Bureau of Mines Experiment Station was tasked with calculating the ventilation requirements that would provide safety from exposure to automobile exhaust carbon monoxide (CO) while balancing the cost of providing ventilation. As the level of ambient CO which was comfortably tolera...
Source: Undersea and Hyperbaric Medicine - March 1, 2021 Category: Sports Medicine Authors: Neil B Hampson Source Type: research

Hyperbaric oxygen for intracranial abscess
Undersea Hyperb Med. 2021 First-Quarter;48(1):97-102.ABSTRACTThe term "intracranial abscess" (ICA) includes cerebral abscess, subdural empyema, and epidural empyema, which share many diagnostic and therapeutic similarities and, frequently, very similar etiologies. Infection may occur and spread from a contiguous infection such as sinusitis, otitis, mastoiditis, or dental infection; hematogenous seeding; or cranial trauma. In view of the high morbidity and mortality of ICA and the fact that hyperbaric oxygen therapy (HBO2) is relatively non-invasive and carries a low complication rate, the risk-benefit ratio favor...
Source: Undersea and Hyperbaric Medicine - March 1, 2021 Category: Sports Medicine Authors: Edward O Tomoye Richard E Moon Source Type: research

Letter: HBO2 combined with steroid therapy for sudden sensorineural hearing loss within two weeks
Undersea Hyperb Med. 2021 First-Quarter;48(1):103-104.NO ABSTRACTPMID:33648040 (Source: Undersea and Hyperbaric Medicine)
Source: Undersea and Hyperbaric Medicine - March 1, 2021 Category: Sports Medicine Authors: Hui-Jun Hu Wei Zhang Dan-Feng Fan Source Type: research

Access to emergent hyperbaric oxygen (HBO2) therapy: an urgent problem in health care delivery in the United States.
Authors: PMID: 33227842 [PubMed - in process] (Source: Undersea and Hyperbaric Medicine)
Source: Undersea and Hyperbaric Medicine - November 25, 2020 Category: Sports Medicine Tags: Undersea Hyperb Med Source Type: research

Hyperbaric oxygen as a treatment for COVID-19 infection?
Abstract Recently the internet has been abuzz with new ideas to treat COVID-19, including hyperbaric oxygen (HBO2) therapy, undoubtedly driven by the fact that until recently there have been few therapeutic options for this highly contagious and often lethal infection. . . . Refractory hypoxemia is certainly treatable with hyperbaric oxygen due to the obvious effect of increasing inspired oxygen partial pressure (PO2), the major reason for using HBO2 for its established indications. However, the length of time during which patients can safely be administered HBO2 inside a chamber is limited, due to practical issue...
Source: Undersea and Hyperbaric Medicine - June 25, 2020 Category: Sports Medicine Authors: Moon RD, Weaver LK Tags: Undersea Hyperb Med Source Type: research

Hyperbaric oxygen therapy may be effective to improve hypoxemia in patients with severe COVID-2019 pneumonia: two case reports.
Conclusion: Our preliminary uncontrolled case reports suggest that HBO2 therapy may promptly improve the progressive hypoxemia of patients with COVID-2019 pneumonia. However, the limited sample size and study design preclude a definitive statement about the potential effectiveness of HBO2 therapy to COVID-2019 pneumonia. It requires evaluation in randomized clinical trials in future. PMID: 32574433 [PubMed - in process] (Source: Undersea and Hyperbaric Medicine)
Source: Undersea and Hyperbaric Medicine - June 25, 2020 Category: Sports Medicine Authors: Guo D, Pan S, Wang M, Guo Y Tags: Undersea Hyperb Med Source Type: research

Roflumilast, a phosphodiesterase-4 inhibitor, improves hyperoxia-induced lung injury via anti-inflammation.
This study aimed to investigate the protective effects of roflumilast on hyperoxia-induced acute lung injury (HALI) in a rat model. Male Sprague-Dawley rats were randomly assigned into: control group; HALI group; 2.5 mg/kg roflumilast group; and 5 mg/kg roflumilast group. Rats were pressurized to 250 kPa with pure oxygen to induce lung injury. In the roflumilast groups, rats were orally administered with roflumilast at 2.5 or 5 mg/kg once before hyperoxia exposure and once daily for two days after exposure. Rats were sacrificed 72 hours after hyperoxia exposure. The lung tissues were collected for the detection of lung wat...
Source: Undersea and Hyperbaric Medicine - June 25, 2020 Category: Sports Medicine Authors: Cao HY, Yu TH, Han CH, Liu WW, Zhang PX, Tang P Tags: Undersea Hyperb Med Source Type: research

Nitric oxide in exhaled gas and tetrahydrobiopterin in plasma after exposure to hyperoxia.
Abstract The fraction of nitric oxide in exhaled gas (FENO) is decreased after exposure to hyperoxia in vivo, although the mechanisms for this decrease is not clear. A key co-factor for nitric oxide synthase (NOS), tetrahydrobiopterin (BH4), has been shown to be oxidized in vitro when exposed to hyperoxia. We hypothesized that the decrease of FENO is due to decreased enzymatic generation of NO due to oxidation of BH4. The present study was performed to investigate the relationship between levels of FENO and plasma BH4 following hyperoxic exposure in humans. Two groups of healthy subjects were exposed to 100% oxyge...
Source: Undersea and Hyperbaric Medicine - June 25, 2020 Category: Sports Medicine Authors: Hesthammer R, Dahle S, Storesund JP, Eide T, Djurhuus R, Svardal AM, Thorsen E Tags: Undersea Hyperb Med Source Type: research

Incidence of decompression sickness in hypobaric hypoxia training.
In this study we aimed to determine the incidence of altitude-induced DCS and the symptoms manifested in trainees and inside chamber observers (ICOs) during the training sessions. We retrospectively reviewed the records of DCS cases during the period of January 1, 2011, and October 1, 2018. The records of 6,657 trainees and 615 ICOs were evaluated. The gender distribution in 6,657 trainees was 6,578 (98.81%) male and 79 (1.19%) female. The numbers of DCS cases in trainees and ICOs were six (0.09%) and two (0.33%), respectively [(ICOs versus trainees - odds ratio (OR): 3.574; 95% CI 0.720-17.744; (p> 0.05)]. All ICOs wer...
Source: Undersea and Hyperbaric Medicine - June 25, 2020 Category: Sports Medicine Authors: Ercan E, Demir AE, Sabaner E, Toklu AS Tags: Undersea Hyperb Med Source Type: research

In-situ simulation for the detection of latent risk threats in a hyperbaric medicine department.
Abstract Simulation (SIM) can be used in the quality improvement process to discover latent risk threats (LRTs) by running in-situ simulation cases in the clinical environment. We utilized this methodology in the hyperbaric chamber to run six in-situ SIM sessions between February 2017 and January 2019. The debriefing portion of each SIM was used to discuss and document all discovered LRTs. These safety threats were aggregated and categorized, resulting in a total of 22 unique LRTs. LRTs included problems or challenges with equipment, team education, policy/processes, communications, and medications. At a three-mon...
Source: Undersea and Hyperbaric Medicine - June 25, 2020 Category: Sports Medicine Authors: Paetow G, Logue C, TenBrink W, Zarzar R, Driehorst M, Brown L, Jensen A, Omodt S, Hart D Tags: Undersea Hyperb Med Source Type: research

Middle-ear barotrauma aft er hyperbaric oxygen therapy: a five-year retrospective analysis on 2,610 patients.
Conclusion: MEB is a common condition responsible for many premature discontinuations of HBO2. Its origin is multifactorial, associating non-modifiable and modifiable factors. Better management of this affection will further contribute to making HBO2 a low-risk treatment. PMID: 32574438 [PubMed - in process] (Source: Undersea and Hyperbaric Medicine)
Source: Undersea and Hyperbaric Medicine - June 25, 2020 Category: Sports Medicine Authors: Edinguele WFOP, Barberon B, Poussard J, Thomas E, Reynier JC, Coulange M Tags: Undersea Hyperb Med Source Type: research

Gunshot damage to monoplace hyperbaric chamber acrylic.
Conclusion: An intact or pressurized chamber performs differently than stand-alone acrylic sections under firearms testing. In a worst-case active shooter scenario, the pressurized monoplace chamber tested posed no additional threat to bystanders beyond the significant risk of ricochet. PMID: 32574439 [PubMed - in process] (Source: Undersea and Hyperbaric Medicine)
Source: Undersea and Hyperbaric Medicine - June 25, 2020 Category: Sports Medicine Authors: Weaver LK, Deru K, Foley J Tags: Undersea Hyperb Med Source Type: research

Successful use of hyperbaric oxygen therapy for limb salvage of acute limb ischemia as a complication of acute carbon monoxide poisoning.
Abstract Acute limb ischemia (ALI) as a complication of acute carbon monoxide (CO) poisoning is rare. Several reports have utilized hyperbaric oxygen therapy (HBO2) as an adjunctive therapy for peripheral arterial diseases. However, no study has yet described the use of HBO2 for ALI precipitated by CO poisoning. Herein we report successful limb salvage achieved with adjunctive HBO2 and conventional therapies in a patient with CO-induced ALI. A 69-year-old man was admitted with acute CO poisoning; ALI of both lower extremities occurred on hospitalization day 3. Pre-existing risk factors for ALI other than CO were n...
Source: Undersea and Hyperbaric Medicine - June 25, 2020 Category: Sports Medicine Authors: Kim YS, Youn YJ, Cha YS Tags: Undersea Hyperb Med Source Type: research

Management of stage 0 medication-related osteonecrosis of the jaw with hyperbaric oxygen therapy: a case report and review of the literature.
This report describes a 64-year-old woman with stage 0 MRONJ of the bilateral mandible, refractory to clindamycin and local debridement, who was subsequently managed successfully with amoxicillin/clavulanate and HBO2 therapy. The authors also explore the current literature on the pathophysiology of MRONJ and the potential role of hyperbaric oxygen in its treatment. PMID: 32574441 [PubMed - in process] (Source: Undersea and Hyperbaric Medicine)
Source: Undersea and Hyperbaric Medicine - June 25, 2020 Category: Sports Medicine Authors: Lin LJ, Alfonso AR, Ross FL, Chiu ES, Fleisher KE Tags: Undersea Hyperb Med Source Type: research

Whole-body active heating does not preserve finger temperature or manual dexterity during cold-water immersion.
Abstract Background: Cold-water immersion impairs manual dexterity when finger temperature is below 15°C. This exposes divers to increased risk of error. We hypothesized that whole-body active heating would maintain finger temperatures and dexterity during cold-water immersion. Methods: Twelve subjects (six males) (22 ± 2 years old; BMI 23.9 ± 2.5; body fat 16 ± 6%) completed 60-minute head-out water immersion (HOWI) wearing a 7mm wetsuit and 3mm gloves in thermoneutral water (TN 25°C) and cold water (CW 10°C) while wearing a water-perfused suit (WP) with 37°C water circul...
Source: Undersea and Hyperbaric Medicine - June 25, 2020 Category: Sports Medicine Authors: Wheelock CE, Hess HW, Schlader ZJ, Johnson BJ, Hostler D Tags: Undersea Hyperb Med Source Type: research

Hyperoxic myopia: a case series of four divers.
JP Abstract Hyperoxic myopia is a phenomenon reported in individuals who have prolonged exposure to an increased partial pressure of oxygen (PO2) and subsequently have a myopic (nearsighted) change in their vision. To date, there are numerous accounts of hyperoxic myopia in dry hyperbaric oxygen treatment patients; however, there have been only three confirmed cases reported in wet divers. This case series adds four confirmed cases of hyperoxic myopia in wet divers using 1.35 atmospheres (ATM) PO2 at the Navy Experimental Diving Unit (NEDU). The four divers involved were the first author's patients at NEDU. Condi...
Source: Undersea and Hyperbaric Medicine - June 25, 2020 Category: Sports Medicine Authors: Brügger JW, Rauscher GA, Florian JP Tags: Undersea Hyperb Med Source Type: research

Branch-like gas in a commercial diver's liver: a case report.
We report the case of a 42-year-old commercial diver who presented with palpitations, arthralgia, tachypnea and vomiting after three hours of repetitive dives to 25-30 meters below sea level (msw). He was diagnosed with severe decompression sickness (Type II DCS) based on his dive history, his abrupt ascent to the surface within minutes, and systemic symptoms with mild hypovolemic shock. Besides remarkable cutis marmorata on the torso, the patient was also found positive for diffuse branch-like pneumatosis in the liver, mesentery and intestines on an abdominal computed tomography (CT). His vitals were relatively stable, wi...
Source: Undersea and Hyperbaric Medicine - June 25, 2020 Category: Sports Medicine Authors: Yu T, Liu L, Xu F, Wu D, Su Y, Sun Q Tags: Undersea Hyperb Med Source Type: research

HBO2 for sudden sensorineural hearing loss.
Abstract Sudden sensorineural hearing loss (SSNHL) presents as an abrupt onset of hearing loss; 88% of these presentations are idiopathic (ISSHL). Many mechanisms of injury and etiopathologies have been postulated, but they share a common result - hypoxia of the organ of Corti leading to hair cell-cilia fusion, synaptic, dendritic swelling and sustained depolarization. Of all of the various treatments tried, only corticosteroids and hyperbaric oxygen (HBO2) therapy have shown benefit in randomized controlled trials (RCTs). This paper reviews the pathophysiology of SSNHL, the variety of treatments studied, and the ...
Source: Undersea and Hyperbaric Medicine - June 25, 2020 Category: Sports Medicine Authors: LeGros TL, Murphy-Lavoie H Tags: Undersea Hyperb Med Source Type: research

UHMS Position Statement: Hyperbaric Oxygen (HBO2) for COVID-19 Patients.
Authors: Abstract There have been numerous recent inquiries regarding use of hyperbaric oxygen (HBO2) for patients with COVID-19. Questions have been raised pertinent to two possible mechanisms for HBO2 in this clinical context. The UHMS Hyperbaric Oxygen Therapy Committee, UHMS Executive Committee, with collaborative input from multiple senior UHMS members and researchers have drafted this position statement. PMID: 32574446 [PubMed - in process] (Source: Undersea and Hyperbaric Medicine)
Source: Undersea and Hyperbaric Medicine - June 25, 2020 Category: Sports Medicine Tags: Undersea Hyperb Med Source Type: research

HBO2 for COVID-19: Clinical trials at clinicaltrials.gov.
Authors: PMID: 32574447 [PubMed - in process] (Source: Undersea and Hyperbaric Medicine)
Source: Undersea and Hyperbaric Medicine - June 25, 2020 Category: Sports Medicine Tags: Undersea Hyperb Med Source Type: research

Track 1: Undersea medicine.
Authors: PMID: 32574448 [PubMed - in process] (Source: Undersea and Hyperbaric Medicine)
Source: Undersea and Hyperbaric Medicine - June 25, 2020 Category: Sports Medicine Tags: Undersea Hyperb Med Source Type: research

Track 2: Clinical hyperbaric medicine.
Authors: PMID: 32574449 [PubMed - in process] (Source: Undersea and Hyperbaric Medicine)
Source: Undersea and Hyperbaric Medicine - June 25, 2020 Category: Sports Medicine Tags: Undersea Hyperb Med Source Type: research

A discussion about sensorineural hearing loss: Response
, Kralova E PMID: 32181997 [PubMed - as supplied by publisher] (Source: Undersea and Hyperbaric Medicine)
Source: Undersea and Hyperbaric Medicine - February 29, 2020 Category: Sports Medicine Authors: Krajcovicova Z, Vladimír, Rastislav Z, Matisaková I, Vecera J, Kralova E Tags: Undersea Hyperb Med Source Type: research

The Letter from Dr. Steinemann
PMID: 31689016 [PubMed - in process] (Source: Undersea and Hyperbaric Medicine)
Source: Undersea and Hyperbaric Medicine - November 8, 2019 Category: Sports Medicine Authors: Steinemann S Tags: Undersea Hyperb Med Source Type: research

HBO2 for radiation cystitis
PMID: 31689017 [PubMed - in process] (Source: Undersea and Hyperbaric Medicine)
Source: Undersea and Hyperbaric Medicine - November 8, 2019 Category: Sports Medicine Authors: Clarke R Tags: Undersea Hyperb Med Source Type: research

Evaluation of fatal diving accidents in Turkey
In this study, autopsy files of fatal dive accident cases were reviewed to evaluate demographic data, type of diving, purpose of dive, seasonal distribution, autopsy findings, and causes of death. We reviewed 56 fatal dive accident files from autopsy units in cities where dive activities are concentrated and from the archive of the Turkish Underwater Federation. Four cases were excluded from the study since we were unable to obtain autopsy reports. Of 52 cases there were 20 scuba divers, two surface-supplied divers and 30 breath-hold divers. The majority of cases involved males (94%). The average age of 50 cases was 38.6; ...
Source: Undersea and Hyperbaric Medicine - June 7, 2019 Category: Sports Medicine Authors: Koca E, Sam B, Arican N, Toklu AS Tags: Undersea Hyperb Med Source Type: research

The effect of compression rate and slope on the incidence of symptomatic Eustachian tube dysfunction leading to middle ear barotrauma: a Phase I prospective study.
Conclusion: Using a 15-minute linear compression schedule is associated with less symptomatic ETD and less MEB when performing an elective 45 fsw (USN TT9) hyperbaric treatment in a Class A chamber. Asymptomatic ETD and MEB were not considered in this study. PMID: 31051053 [PubMed - in process] (Source: Undersea and Hyperbaric Medicine)
Source: Undersea and Hyperbaric Medicine - February 28, 2019 Category: Sports Medicine Authors: Varughese L, O'Neill OJ, Marker J, Smykowski E, Dayya D Tags: Undersea Hyperb Med Source Type: research

Middle ear barotrauma during hyperbaric oxygen therapy; a review of occurrences in 5,962 patients.
Abstract Hyperbaric-associated middle ear barotrauma (MEB) is one of the most common side effects of the exposure to hyperbaric oxygen (HBO2) therapy. This retrospective observational study of 5,962 patients undergoing longterm therapy for chronic conditions took place at the local Diving and Hyperbaric Medicine Unit (DHMU) in Villafranca-Verona (Italy), a DHMU that administers, in multiplace chambers, more than 20,000 HBO2 treatments per year. The study was designed to weight and analyze both the incidence and severity of MEBs at the facility. Thanks to a systematic recording method over eight years, 2003-2010, w...
Source: Undersea and Hyperbaric Medicine - February 28, 2019 Category: Sports Medicine Authors: Nasole E, Zanon V, Marcolin P, Bosco G Tags: Undersea Hyperb Med Source Type: research

Methods for preventing middle ear barotrauma in computer-controlled pressurization of monoplace hyperbaric chambers.
Abstract Middle ear barotrauma (MEB), one of the side effects of hyperbaric oxygen (HBO2) therapy, sometimes cannot be directly diagnosed during the therapy itself. Instead, its incidence and degree are judged based on subjective statements made by patients when in conversation with medical staff regarding how they feel. To prevent MEB in practice, it is proposed that the tympanic membrane evaluation system and automatic control chamber developed in a previous study be applied as part of a prevention algorithm [16]. The proposed algorithm, which determines and equalizes the unbalanced pressure of a subject based o...
Source: Undersea and Hyperbaric Medicine - February 28, 2019 Category: Sports Medicine Authors: Hwang L, Song M, Lee Y, Shin TM Tags: Undersea Hyperb Med Source Type: research

Effects of sprint interval training on cardiorespiratory fitness while in a hyperbaric oxygen environment.
Conclusion: Cardiorespiratory fitness improved after a two-week SIT regimen, but improvement in peak V̇O2 was not significantly different between ambient and HBO2 groups. PMID: 31051056 [PubMed - in process] (Source: Undersea and Hyperbaric Medicine)
Source: Undersea and Hyperbaric Medicine - February 28, 2019 Category: Sports Medicine Authors: DeCato TW, Bradley SM, Wilson EL, Harlan NP, Villela MA, Weaver LK, Hegewald MJ Tags: Undersea Hyperb Med Source Type: research

Hyperbaric oxygen treatment ameliorates gentamicin-induced nephrotoxicity and expression of kidney injury molecule 1 in the rat model.
In conclusion, HBO2 exposure may be defined as a potential method for the prevention of GM-induced renal toxicity. PMID: 31051057 [PubMed - in process] (Source: Undersea and Hyperbaric Medicine)
Source: Undersea and Hyperbaric Medicine - February 28, 2019 Category: Sports Medicine Authors: Öztopuz Ö, Türkön H, Sehitoglu MH, Büyük B, Uzun M, Ovali MA, Demir U Tags: Undersea Hyperb Med Source Type: research

Operation of a hyperbaric oxygen therapy center in Korea: Report of our experience from a setting in its nascent stages.
Conclusion: After the establishment of the HBO2 center operated by physicians with certification, more patients, including critically ill patients, received HBO2 safely for various diseases. In order to improve the practice of hyperbaric medicine in Korea, the Korean Academy of Undersea and Hyperbaric Medicine (KAUHM), an advanced and well-organized academic society, should communicate often with HBO2 centers, with the aim to set Korean education programs at UHMS course levels and increase reimbursement for HBO2 therapy. PMID: 31051058 [PubMed - in process] (Source: Undersea and Hyperbaric Medicine)
Source: Undersea and Hyperbaric Medicine - February 28, 2019 Category: Sports Medicine Authors: Kim YS, Lee Y, Kim SJ, Hwang SO, Cha YS, Kim H Tags: Undersea Hyperb Med Source Type: research

Hyperbaric oxygen may improve vascular endothelial function in patients undergoing coronary stent implantation.
Conclusion: Using HBO2 therapy as an adjunct treatment in patients undergoing coronary stent implantation may significantly improve vascular endothelial function. HBO2 therapy may have the potential to alter the course of coronary artery disease in the future. Further randomized, multicenter, prospective studies are needed. PMID: 31051059 [PubMed - in process] (Source: Undersea and Hyperbaric Medicine)
Source: Undersea and Hyperbaric Medicine - February 28, 2019 Category: Sports Medicine Authors: Li Y, Hao YF, Wang T, Zhang JF, Liang Y, Xiao WL, Guo X Tags: Undersea Hyperb Med Source Type: research

Rescue of a submerged convulsing diver.
Abstract In 2018, the Medical Panel of the NATO Underwater Diving Working Group (UDWG) discussed the question of the rescue and management of a submerged unresponsive compressed-gas diver. The Panel reviewed the 2012 recommendation by the UHMS Diving Committee with respect to the specific recommendation in a convulsing diver using a half-face mask and separate mouthpiece, to delay surfacing until the clonic phase had subsided if the mouthpiece was in place. There is a paucity of scientific, epidemiological, experimental and observational human studies to substantiate this guidance. Experimental animal studies sugg...
Source: Undersea and Hyperbaric Medicine - February 28, 2019 Category: Sports Medicine Authors: Risberg J, Phillips S Tags: Undersea Hyperb Med Source Type: research

Decrease of tetrahydrobiopterin and NO generation in endothelial cells exposed to simulated diving.
Conclusion: NO generation in intact human endothelial cells was decreased by simulated diving, as well as by hyperoxic exposure, while BH4 levels seem to be affected only by hyperoxia. Hence, the results suggest that BH4 is not the sole determinant of NO generation in HUVEC. PMID: 31051061 [PubMed - in process] (Source: Undersea and Hyperbaric Medicine)
Source: Undersea and Hyperbaric Medicine - February 28, 2019 Category: Sports Medicine Authors: Hesthammer R, Eide T, Thorsen E, Svardal AM, Djurhuus R Tags: Undersea Hyperb Med Source Type: research

Clustering of recreational divers by their health conditions in a database of a citizen science project.
Abstract Divers Alert Network Europe has created a database with a large amount of dive-related data that has been collected since 1993 within the scope of the Diving Safety Laboratory citizen science project. The main objectives of this study are the grouping divers by their health information and revealing significant differences in diving parameters using data mining techniques. Due to the methodology of the project, data cleaning was performed before applying clustering methods in order to eliminate potential mistakes resulting from inaccuracies and missing information. Despite the fact that 63% of the data we...
Source: Undersea and Hyperbaric Medicine - February 28, 2019 Category: Sports Medicine Authors: Ozyigit T, Yavuz C, Egi SM, Pieri M, Balestra C, Marroni A Tags: Undersea Hyperb Med Source Type: research

Dehydration of a diver during a hyperbaric chamber exposure with oxygen decompression.
Conclusions: Hyperbaric conditions are conducive to the dehydration of the diver's body, however to a degree which does not lead to an occurrence of health hazards. Good care for one's health through proper nutrition and hydration are sufficient preventive and protective measures. PMID: 31051063 [PubMed - in process] (Source: Undersea and Hyperbaric Medicine)
Source: Undersea and Hyperbaric Medicine - February 28, 2019 Category: Sports Medicine Authors: Kaczerska D, Siermontowski P, Kozakiewicz M, Krefft K, Olszański R Tags: Undersea Hyperb Med Source Type: research

Pulmonary barotrauma: assessment and investigation in divers.
Abstract Decompression illness (DCI) is an uncommon problem but can be significant in terms of morbidity and, very rarely, mortality. The mechanisms of DCI are pulmonary barotrauma and decompression sickness due to inert gas supersaturation. After the initial management phase, identification of predisposing factors is important to help advise divers regarding future risk and avoidance. Here we present four cases of DCI where pulmonary barotrauma was the likely causative mechanism. We highlight the important features in assessment for pulmonary barotrauma and advising divers on the risk of a recurrence. PMID: ...
Source: Undersea and Hyperbaric Medicine - February 28, 2019 Category: Sports Medicine Authors: Ashrafi R, Turner M Tags: Undersea Hyperb Med Source Type: research

Delayed hyperbaric oxygen therapy for severe arterial gas embolism following scuba diving: a case report.
We present the case of a 42-year-old female who was critically ill due to an arterial gas embolism (AGE) she experienced while diving in Maui, Hawaii. She presented with shortness of breath and dizziness shortly after surfacing from a scuba dive and then rapidly lost consciousness. The diver then had a complicated hospital course: persistent hypoxemia (likely secondary to aspiration) requiring intubation; markedly elevated creatine kinase; atrial fibrillation requiring cardioversion; and slow neurologic improvement. She had encountered significant delay in treatment due to lack of availability of local hyperbaric oxygen (H...
Source: Undersea and Hyperbaric Medicine - February 28, 2019 Category: Sports Medicine Authors: Sadler C, Latham E, Hollidge M, Boni B, Brett K Tags: Undersea Hyperb Med Source Type: research

Atrial fibrillation associated with carbon monoxide poisoning.
Abstract Carbon monoxide intoxication occurs usually via inhalation of carbon monoxide that is emitted as a result of a fire, furnace, space heater, generator, motor vehicle. A 37-year-old male patient was admitted to the emergency department at about 5:00 a.m., with complaints of nausea, vomiting and headache. He was accompanied by his wife and children. His venous blood gas measures were: pH was 7.29, partial pressure of carbon dioxide (pCO2) was 42 mmHg, partial pressure of oxygen (pO2) was 28 mmHg, carboxyhemoglobin (COHb) was 12.7% (reference interval: 0.5%-2.5%) and oxygen saturation was 52.4%. Electro-cardi...
Source: Undersea and Hyperbaric Medicine - February 28, 2019 Category: Sports Medicine Authors: Demir M, Sahin M, Korkmaz A Tags: Undersea Hyperb Med Source Type: research