Improved Patient Outcomes with Electrocauterization Following Wedge Resection and Curettage for Ingrown Toenails: A Prospective Comparative Study
Conclusion Wedge excision and curettage, followed by electrocauterization of the ingrown toenail is a safe treatment modality with a high success rate, that is evident by a lower recurrence rate, and greater patient satisfaction, with no effect on postoperative pain score or recovery time.PMID:38596153 | PMC:PMC11001453 | DOI:10.1055/s-0043-1777280 (Source: Archives of Plastic Surgery)
Source: Archives of Plastic Surgery - April 10, 2024 Category: Cosmetic Surgery Authors: Marzouq Amarin Raed Al-Taher Khaled Daradka Amal Ibraheem Abd Al Qader Abu Harb Rawan Abd AlMohsen Mohammad Habashneh Nadwa Basem Bustami Yazan Hijazein Hiba Hadadin Sondos Wa'el Sa'dat Al-Najjar Source Type: research

Serotonin receptor 2B induces visceral hyperalgesia in rat model and patients with diarrhea-predominant irritable bowel syndrome
CONCLUSION: Our finding that increased expression of the 5-HT2B receptor contributes to visceral hyperalgesia by inducing TRPV1 expression in IBS-D patients provides important insights into the potential mechanisms underlying IBS-D-associated visceral hyperalgesia.PMID:38596485 | PMC:PMC11000090 | DOI:10.3748/wjg.v30.i10.1431 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - April 10, 2024 Category: Gastroenterology Authors: Zheng-Yang Li Yu-Qing Mao Qian Hua Yong-Hong Sun Hai-Yan Wang Xuan-Guang Ye Jing-Xian Hu Ya-Jie Wang Miao Jiang Source Type: research

Bridging the gap: Unveiling the crisis of physical inactivity in inflammatory bowel diseases
World J Gastroenterol. 2024 Mar 14;30(10):1261-1265. doi: 10.3748/wjg.v30.i10.1261.ABSTRACTIn this editorial we comment on the article titled "Inflammatory bowel diseases patients suffer from significant low levels and barriers to physical activity: The BE-FIT-IBD study" published in a recent issue of the World Journal of Gastroenterology 2023; 29 (41): 5668-5682. Inflammatory bowel diseases (IBD) are emerging as a significant global health concern as their incidence continues to rise on a global scale, with detrimental impacts on quality of life. While many advances have been made regarding the management of the disease, ...
Source: World Journal of Gastroenterology : WJG - April 10, 2024 Category: Gastroenterology Authors: Remus Stafie Ana-Maria Singeap Adrian Rotaru Carol Stanciu Anca Trifan Source Type: research

Bridging the gap: Unveiling the crisis of physical inactivity in inflammatory bowel diseases
World J Gastroenterol. 2024 Mar 14;30(10):1261-1265. doi: 10.3748/wjg.v30.i10.1261.ABSTRACTIn this editorial we comment on the article titled "Inflammatory bowel diseases patients suffer from significant low levels and barriers to physical activity: The BE-FIT-IBD study" published in a recent issue of the World Journal of Gastroenterology 2023; 29 (41): 5668-5682. Inflammatory bowel diseases (IBD) are emerging as a significant global health concern as their incidence continues to rise on a global scale, with detrimental impacts on quality of life. While many advances have been made regarding the management of the disease, ...
Source: World Journal of Gastroenterology - April 10, 2024 Category: Gastroenterology Authors: Remus Stafie Ana-Maria Singeap Adrian Rotaru Carol Stanciu Anca Trifan Source Type: research

Serotonin receptor 2B induces visceral hyperalgesia in rat model and patients with diarrhea-predominant irritable bowel syndrome
CONCLUSION: Our finding that increased expression of the 5-HT2B receptor contributes to visceral hyperalgesia by inducing TRPV1 expression in IBS-D patients provides important insights into the potential mechanisms underlying IBS-D-associated visceral hyperalgesia.PMID:38596485 | PMC:PMC11000090 | DOI:10.3748/wjg.v30.i10.1431 (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - April 10, 2024 Category: Gastroenterology Authors: Zheng-Yang Li Yu-Qing Mao Qian Hua Yong-Hong Sun Hai-Yan Wang Xuan-Guang Ye Jing-Xian Hu Ya-Jie Wang Miao Jiang Source Type: research

Quality of Life in Patients With Chronic Limb-Threatening Ischemia Treated With Revascularization
CONCLUSIONS: Among patients with chronic limb-threatening ischemia deemed eligible for either Bypass or Endo, revascularization resulted in significant and clinically meaningful improvements in HRQoL. In patients with an available single-segment great saphenous vein for bypass, but not among those without one, Endo was statistically superior on some HRQoL measures; however, these differences were below the threshold of clinically meaningful difference.PMID:38597097 | DOI:10.1161/CIRCULATIONAHA.123.065277 (Source: Circulation)
Source: Circulation - April 10, 2024 Category: Cardiology Authors: Matthew T Menard Alik Farber Richard J Powell Kenneth Rosenfield Michael S Conte Taye H Hamza John A Kaufman Mark J Cziraky Mark A Creager Michael D Dake Michael R Jaff Diane Reid George Sopko Christopher J White Michael B Strong Max van Over Emiliano Chi Source Type: research

The clinical value of β-blockers in patients with stable angina
Curr Med Res Opin. 2024;40(sup1):33-41. doi: 10.1080/03007995.2024.2317443. Epub 2024 Apr 10.ABSTRACTStable angina, one manifestation of chronic coronary syndrome (CCS), is characterised by intermittent episodes of insufficient blood supply to the myocardium, provoking symptoms of myocardial ischaemia, particularly chest pain. These attacks usually occur during exercise or stress. Anti-ischaemic drugs are the mainstay of pharmacologic management of CCS with symptoms of angina. β-blockers reduce heart rate and myocardial contractility, thus reducing myocardial oxygen consumption. These drugs have been shown to ameliorate t...
Source: Current Medical Research and Opinion - April 10, 2024 Category: Research Authors: Paolo Palatini Jose R Faria-Neto Raul D Santos Source Type: research

Improved Patient Outcomes with Electrocauterization Following Wedge Resection and Curettage for Ingrown Toenails: A Prospective Comparative Study
Conclusion Wedge excision and curettage, followed by electrocauterization of the ingrown toenail is a safe treatment modality with a high success rate, that is evident by a lower recurrence rate, and greater patient satisfaction, with no effect on postoperative pain score or recovery time.PMID:38596153 | PMC:PMC11001453 | DOI:10.1055/s-0043-1777280 (Source: Archives of Plastic Surgery)
Source: Archives of Plastic Surgery - April 10, 2024 Category: Cosmetic Surgery Authors: Marzouq Amarin Raed Al-Taher Khaled Daradka Amal Ibraheem Abd Al Qader Abu Harb Rawan Abd AlMohsen Mohammad Habashneh Nadwa Basem Bustami Yazan Hijazein Hiba Hadadin Sondos Wa'el Sa'dat Al-Najjar Source Type: research

Comprehensive management of challenging recurrent aortoiliac and lower extremity occlusive disease with simultaneous modified-covered endovascular reconstruction of the aortic bifurcation, inferior mesenteric artery snorkel, and lower extremity bypass
CONCLUSION: This comprehensive management approach, combining simultaneous modified-CERAB, IMA snorkel, and LE bypass, provides an effective alternative for addressing complex AIOD and LE occlusive disease patients with hostile abdomen.PMID:38596896 | DOI:10.1177/17085381241245874 (Source: Vascular)
Source: Vascular - April 10, 2024 Category: Surgery Authors: Wei Li Dixon Santana Cooper Phillips Source Type: research

Bridging the gap: Unveiling the crisis of physical inactivity in inflammatory bowel diseases
World J Gastroenterol. 2024 Mar 14;30(10):1261-1265. doi: 10.3748/wjg.v30.i10.1261.ABSTRACTIn this editorial we comment on the article titled "Inflammatory bowel diseases patients suffer from significant low levels and barriers to physical activity: The BE-FIT-IBD study" published in a recent issue of the World Journal of Gastroenterology 2023; 29 (41): 5668-5682. Inflammatory bowel diseases (IBD) are emerging as a significant global health concern as their incidence continues to rise on a global scale, with detrimental impacts on quality of life. While many advances have been made regarding the management of the disease, ...
Source: World Journal of Gastroenterology : WJG - April 10, 2024 Category: Gastroenterology Authors: Remus Stafie Ana-Maria Singeap Adrian Rotaru Carol Stanciu Anca Trifan Source Type: research

Serotonin receptor 2B induces visceral hyperalgesia in rat model and patients with diarrhea-predominant irritable bowel syndrome
CONCLUSION: Our finding that increased expression of the 5-HT2B receptor contributes to visceral hyperalgesia by inducing TRPV1 expression in IBS-D patients provides important insights into the potential mechanisms underlying IBS-D-associated visceral hyperalgesia.PMID:38596485 | PMC:PMC11000090 | DOI:10.3748/wjg.v30.i10.1431 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - April 10, 2024 Category: Gastroenterology Authors: Zheng-Yang Li Yu-Qing Mao Qian Hua Yong-Hong Sun Hai-Yan Wang Xuan-Guang Ye Jing-Xian Hu Ya-Jie Wang Miao Jiang Source Type: research

Bridging the gap: Unveiling the crisis of physical inactivity in inflammatory bowel diseases
World J Gastroenterol. 2024 Mar 14;30(10):1261-1265. doi: 10.3748/wjg.v30.i10.1261.ABSTRACTIn this editorial we comment on the article titled "Inflammatory bowel diseases patients suffer from significant low levels and barriers to physical activity: The BE-FIT-IBD study" published in a recent issue of the World Journal of Gastroenterology 2023; 29 (41): 5668-5682. Inflammatory bowel diseases (IBD) are emerging as a significant global health concern as their incidence continues to rise on a global scale, with detrimental impacts on quality of life. While many advances have been made regarding the management of the disease, ...
Source: World Journal of Gastroenterology - April 10, 2024 Category: Gastroenterology Authors: Remus Stafie Ana-Maria Singeap Adrian Rotaru Carol Stanciu Anca Trifan Source Type: research

Serotonin receptor 2B induces visceral hyperalgesia in rat model and patients with diarrhea-predominant irritable bowel syndrome
CONCLUSION: Our finding that increased expression of the 5-HT2B receptor contributes to visceral hyperalgesia by inducing TRPV1 expression in IBS-D patients provides important insights into the potential mechanisms underlying IBS-D-associated visceral hyperalgesia.PMID:38596485 | PMC:PMC11000090 | DOI:10.3748/wjg.v30.i10.1431 (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - April 10, 2024 Category: Gastroenterology Authors: Zheng-Yang Li Yu-Qing Mao Qian Hua Yong-Hong Sun Hai-Yan Wang Xuan-Guang Ye Jing-Xian Hu Ya-Jie Wang Miao Jiang Source Type: research

Quality of Life in Patients With Chronic Limb-Threatening Ischemia Treated With Revascularization
CONCLUSIONS: Among patients with chronic limb-threatening ischemia deemed eligible for either Bypass or Endo, revascularization resulted in significant and clinically meaningful improvements in HRQoL. In patients with an available single-segment great saphenous vein for bypass, but not among those without one, Endo was statistically superior on some HRQoL measures; however, these differences were below the threshold of clinically meaningful difference.PMID:38597097 | DOI:10.1161/CIRCULATIONAHA.123.065277 (Source: Circulation)
Source: Circulation - April 10, 2024 Category: Cardiology Authors: Matthew T Menard Alik Farber Richard J Powell Kenneth Rosenfield Michael S Conte Taye H Hamza John A Kaufman Mark J Cziraky Mark A Creager Michael D Dake Michael R Jaff Diane Reid George Sopko Christopher J White Michael B Strong Max van Over Emiliano Chi Source Type: research

The clinical value of β-blockers in patients with stable angina
Curr Med Res Opin. 2024;40(sup1):33-41. doi: 10.1080/03007995.2024.2317443. Epub 2024 Apr 10.ABSTRACTStable angina, one manifestation of chronic coronary syndrome (CCS), is characterised by intermittent episodes of insufficient blood supply to the myocardium, provoking symptoms of myocardial ischaemia, particularly chest pain. These attacks usually occur during exercise or stress. Anti-ischaemic drugs are the mainstay of pharmacologic management of CCS with symptoms of angina. β-blockers reduce heart rate and myocardial contractility, thus reducing myocardial oxygen consumption. These drugs have been shown to ameliorate t...
Source: Current Medical Research and Opinion - April 10, 2024 Category: Research Authors: Paolo Palatini Jose R Faria-Neto Raul D Santos Source Type: research