A survey on the short to medium-term satisfaction of neurological patients treated by functional surgery for the correction of limb deformities
CONCLUSION: According to patients and caregivers, FS was satisfactory in the short and medium terms, following improvements in all the ICF domains for most patients.PMID:38756086 | DOI:10.1080/03007995.2024.2352855 (Source: Current Medical Research and Opinion)
Source: Current Medical Research and Opinion - May 17, 2024 Category: Research Authors: Paolo Zerbinati Davide Mazzoli Martina Galletti Giacomo Basini Chiara Rambelli Francesca Mascioli Maria Chiara B ò Caterina Delia Ludovica Petroselli Maria Chiara Vulpiani Paolo Prati Jonathan Bemporad Andrea Merlo Source Type: research

Economic burden of generalized myasthenia gravis (MG) in the United States and the impact of common comorbidities and acute MG- events
Conclusions: gMG is associated with substantial incremental costs and HRU, with inpatient costs driving the total incremental costs. Costs increased by 20% and 34% among patients with cardiometabolic and psychiatric conditions, respectively, and over 3 times among those with acute MG-related events. gMG is a complex disease requiring management of comorbidities and treatment options that can prevent acute symptomatic events.PMID:38745448 | DOI:10.1080/03007995.2024.2353381 (Source: Current Medical Research and Opinion)
Source: Current Medical Research and Opinion - May 15, 2024 Category: Research Authors: Maryia Zhdanava Jacqueline Pesa Porpong Boonmak Qian Cai Dominic Pilon Zia Choudhry Nizar Souayah Source Type: research

Panel Interview of ONcology practices with Emergent Experience of teclistamab in the Real world: the TecPIONEER Study
CONCLUSION: The results consolidated practice-based experiences and indicated diverse RW SUD models and patient management strategies in practices with familiarity with teclistamab AE management and ToC protocols. Inpatient SUD is common, with expectations that approaches will evolve toward outpatient or community-based administration. Further research is needed to investigate outcomes of different care models and AE management strategies.PMID:38745451 | DOI:10.1080/03007995.2024.2352856 (Source: Current Medical Research and Opinion)
Source: Current Medical Research and Opinion - May 15, 2024 Category: Research Authors: Benjamin A Derman Meaghan Roach Dee Lin Bingcao Wu Richard Murphy Nina Kim Margaret Doyle Nadya Prood Jessica Fowler Alexander Marshall Amal Jamaleddine Agne Paner-Straseviciute Source Type: research

Economic burden of generalized myasthenia gravis (MG) in the United States and the impact of common comorbidities and acute MG- events
Conclusions: gMG is associated with substantial incremental costs and HRU, with inpatient costs driving the total incremental costs. Costs increased by 20% and 34% among patients with cardiometabolic and psychiatric conditions, respectively, and over 3 times among those with acute MG-related events. gMG is a complex disease requiring management of comorbidities and treatment options that can prevent acute symptomatic events.PMID:38745448 | DOI:10.1080/03007995.2024.2353381 (Source: Current Medical Research and Opinion)
Source: Current Medical Research and Opinion - May 15, 2024 Category: Research Authors: Maryia Zhdanava Jacqueline Pesa Porpong Boonmak Qian Cai Dominic Pilon Zia Choudhry Nizar Souayah Source Type: research

Panel Interview of ONcology practices with Emergent Experience of teclistamab in the Real world: The TecPIONEER Study
CONCLUSION: The results consolidated practice-based experiences and indicated diverse RW SUD models and patient management strategies in practices with familiarity with teclistamab AE management and ToC protocols. Inpatient SUD is common, with expectations that approaches will evolve toward outpatient or community-based administration. Further research is needed to investigate outcomes of different care models and AE management strategies.PMID:38745451 | DOI:10.1080/03007995.2024.2352856 (Source: Current Medical Research and Opinion)
Source: Current Medical Research and Opinion - May 15, 2024 Category: Research Authors: Benjamin A Derman Meaghan Roach Dee Lin Bingcao Wu Richard Murphy Nina Kim Margaret Doyle Nadya Prood Jessica Fowler Alexander Marshall Amal Jamaleddine Agne Paner-Straseviciute Source Type: research

Real-world outcomes in patients with chronic spontaneous urticaria receiving omalizumab: insights from a clinical practice survey
Conclusion: Around two-thirds of patients with CSU considered eligible for omalizumab were not receiving the guideline-recommended therapy. Patients receiving omalizumab had better real-world outcomes compared with patients not receiving omalizumab. Ensuring patients receive the most appropriate treatment could benefit patients with CSU.PMID:38738706 | DOI:10.1080/03007995.2024.2354534 (Source: Current Medical Research and Opinion)
Source: Current Medical Research and Opinion - May 13, 2024 Category: Research Authors: Arpamas Seetasith Michael Holden James Hetherington Aaron Keal Phoebe Salmon Jonathan A Bernstein Thomas B Casale Source Type: research

Exploring treatment strategies for paroxysmal nocturnal hemoglobinuria: an overview of registered clinical trials
Curr Med Res Opin. 2024 May 10:1-20. doi: 10.1080/03007995.2024.2354533. Online ahead of print.ABSTRACTParoxysmal nocturnal hemoglobinuria (PNH) is a rare, acquired disease in which blood cells lack anchored proteins that regulate the complement system. The erythrocytes are then destroyed because of uncontrolled complement activity, leading to intravascular hemolysis (IVH) and a high risk of thrombosis outcome.A huge alteration in the treatment of the disease was the development of terminal complement inhibitors, with the achievement of IVH blockade, reduction or abolishment of red blood cell (RBC) transfusions, and thromb...
Source: Current Medical Research and Opinion - May 10, 2024 Category: Research Authors: Vanda P Peixoto Cristina Prud êncio M ónica Vieira Source Type: research

Influence of tricuspid regurgitation on the prognosis of patients with cardiogenic shock
CONCLUSION: The occurrence of pre-existing TR II°/III° was independently related with 30-day all-cause mortality in CS-patients without AMI. However, no prognostic influence was observed in CS-patients with AMI.PMID:38720658 | DOI:10.1080/03007995.2024.2353908 (Source: Current Medical Research and Opinion)
Source: Current Medical Research and Opinion - May 9, 2024 Category: Research Authors: Marinela Ruka Tobias Schupp Kathrin Weidner Sascha Egner-Walter Jan Forner Kambis Mashayekhi P éter Tajti Mohamed Ayoub Muharrem Akin Michael Behnes Ibrahim Akin Jonas Rusnak Source Type: research