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Antidepressant medications have evolved in terms of speed of onset of efficacy: how can we best measure antidepressant treatment response?
Curr Med Res Opin. 2024 Feb 25:1-8. doi: 10.1080/03007995.2024.2323638. Online ahead of print.NO ABSTRACTPMID:38404189 | DOI:10.1080/03007995.2024.2323638 (Source: Current Medical Research and Opinion)
Source: Current Medical Research and Opinion - February 26, 2024 Category: Research Authors: Jan A Sedway Mark G A Opler Leslie Citrome Source Type: research

Model-based simulation of glycaemic effect and body weight loss when switching from semaglutide or dulaglutide to once weekly tirzepatide
CONCLUSION: In this model-based simulation, switching from approved maintenance doses of semaglutide or dulaglutide to tirzepatide, even at the lowest approved maintenance dose of 5 mg, showed the potential to further improve HbA1c and body weight reductions.PMID:38407177 | DOI:10.1080/03007995.2024.2322072 (Source: Current Medical Research and Opinion)
Source: Current Medical Research and Opinion - February 26, 2024 Category: Research Authors: Shweta Urva Joshua A Levine Karen Schneck Cheng Cai Tang Source Type: research

Personality dimensions and treatment adherence among glaucoma patients: the role of self-transcendence
CONCLUSIONS: The results suggest that POAG patients with higher scores on the Self-Transcendent personality dimension are more likely to experience difficulties adhering to medication regimen. The study highlights the importance of a holistic approach to glaucoma treatment, which takes into account not only the biological aspects of disease but also the psychosocial factors that influence patient behavior. Healthcare providers may need to consider glaucoma patients' personality dimensions, beliefs and values when developing treatment plans and strategies to improve medication adherence.PMID:38404158 | DOI:10.1080/03007995....
Source: Current Medical Research and Opinion - February 26, 2024 Category: Research Authors: Dina Le šin Gaćina Darko Mar činko Tomislav Kuzman Ivan Škegro Sania Vidas Pauk Bernarda Škegro Martina Tomi ć Tomislav Bulum Sonja Jandrokovi ć Source Type: research

Patient characteristics, treatment patterns, healthcare resource utilization, and costs among patients diagnosed with neurofibromatosis type 1 with and without plexiform neurofibromas in Japan
CONCLUSIONS: NF1 is treated primarily with supportive care with analgesics/non-steroidal anti-inflammatory drugs being the most frequently prescribed NF1 medications in Japan. Findings underscored the unmet need and substantial economic burden among patients with NF1 and highlighted the need for new treatment options for patients with this disease.PMID:38404173 | DOI:10.1080/03007995.2024.2322698 (Source: Current Medical Research and Opinion)
Source: Current Medical Research and Opinion - February 26, 2024 Category: Research Authors: Yuichi Yoshida Keiichi Tozawa Ryo Koto Chikako Iwao Yong-Jin Kim Lu Ban Volkan Barut Source Type: research

Combining biomarkers of BNIP3 L, S100B, NSE and accessible measures to prediction sepsis-associated encephalopathy: a prospective observational study
CONCLUSIONS: The Logistic regression showed that combination model was strongly correlated with cognitive dysfunction in sepsis patients.PMID:38385550 | DOI:10.1080/03007995.2024.2322059 (Source: Current Medical Research and Opinion)
Source: Current Medical Research and Opinion - February 22, 2024 Category: Research Authors: Nannan Zhang Keliang Xie Fei Yang Yunying Wang Xinhao Yang Lina Zhao Source Type: research

Measuring the impact of scientific publications and publication extenders: examples of novel approaches
Curr Med Res Opin. 2024 Feb 20:1-15. doi: 10.1080/03007995.2024.2320849. Online ahead of print.ABSTRACTDifferent stakeholders, such as authors, research institutions, and healthcare professionals (HCPs) may determine the impact of peer-reviewed publications in different ways. Commonly-used measures of research impact, such as the Journal Impact Factor or the H-index, are not designed to evaluate the impact of individual articles. They are heavily dependent on citations, and therefore only measure impact of the overall journal or researcher respectively, taking months or years to accrue. The past decade has seen the develop...
Source: Current Medical Research and Opinion - February 20, 2024 Category: Research Authors: Avishek Pal Wesley Portegies Jennifer Schwinn Michael Taylor Tomas J Rees Sarah Thomas Kim Brown Gareth Morrell Josh Nicholson Brian Falcone Renu Juneja Source Type: research

Is dependent cannabis use in adult hospitalizations with inflammatory bowel disease associated with major adverse cardiovascular and cerebrovascular events? Insights from National Inpatient Sample Analysis
CONCLUSION: Our study did not find a statistically significant difference in MACCE among hospitalized IBD patients with and without CUD. This emphasizes the need for more extensive prospective studies focusing on the quantity, method, and duration of cannabis use (recreational or medicinal) in patients with IBD.PMID:38376123 | DOI:10.1080/03007995.2024.2321328 (Source: Current Medical Research and Opinion)
Source: Current Medical Research and Opinion - February 20, 2024 Category: Research Authors: Vamsikalyan Borra Nithya Borra Gayatri Bondi Sai Goutham R Yartha Naga Vamsikrishna Machineni Charu Agarwal Karthikeya Ramasahayam Purnachandra Rao Kuchipudi Sravya R Mundla Prerna Bansal Sagar A Bathija Ikechukwu R Ogbu Rupak Desai Source Type: research