Urea breath test for < em > Helicobacter pylori < /em > infection in adult dyspeptic patients: A meta-analysis of diagnostic test accuracy
CONCLUSION: In summary, our study has demonstrated that 13C-UBT has been found to outperform the 14C-UBT, making it the preferred diagnostic approach. Additionally, our results emphasize the significance of carefully considering urea dosage, assessment timing, and measurement techniques for both tests to enhance diagnostic precision. Nevertheless, it is crucial for researchers and clinicians to evaluate the strengths and limitations of our findings before implementing them in practice.PMID:38463019 | PMC:PMC10921142 | DOI:10.3748/wjg.v30.i6.579 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - March 11, 2024 Category: Gastroenterology Authors: Fabian Fellipe Bueno Lemos Caroline Tianeze de Castro Marcel Silva Luz Gabriel Reis Rocha Gabriel Lima Correa Santos Lu ís Guilherme de Oliveira Silva Mariana Santos Calmon Cl áudio Lima Souza Ana Carla Zarpelon-Schutz K ádima Nayara Teixeira Dulciene Source Type: research

Y-Z deformable magnetic ring for the treatment of rectal stricture: A case report and review of literature
CONCLUSION: The Y-Z DMR deformable magnetic ring is an excellent treatment strategy for patients with rectal stenosis and without enterostomy.PMID:38463020 | PMC:PMC10921145 | DOI:10.3748/wjg.v30.i6.599 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - March 11, 2024 Category: Gastroenterology Authors: Miao-Miao Zhang Huan-Chen Sha Yuan-Fa Qin Yi Lyu Xiao-Peng Yan Source Type: research

Diagnostic tools for fecal incontinence: Scoring systems are the crucial first step
World J Gastroenterol. 2024 Feb 14;30(6):516-522. doi: 10.3748/wjg.v30.i6.516.ABSTRACTThe main aim of this editorial is to comment on the recent article published by Garg et al in the World Journal of Gastroenterology 2023; 29: 4593-4603. This original research presents a new scoring system for fecal incontinence. Fecal incontinence is a chronic disease with a severe impact on the quality of life of the patients. Substantial social stigmatization often leads to significant underreporting of the condition even during visits to a specialist and could lead to further mismanagement or non-existent management of the disease. An...
Source: World Journal of Gastroenterology : WJG - March 11, 2024 Category: Gastroenterology Authors: Peter Liptak Martin Duricek Peter Banovcin Source Type: research

Emerging role of exosomes in ulcerative colitis: Targeting NOD-like receptor family pyrin domain containing 3 inflammasome
World J Gastroenterol. 2024 Feb 14;30(6):527-541. doi: 10.3748/wjg.v30.i6.527.ABSTRACTUlcerative colitis (UC) is a chronic recurrent inflammatory bowel disease. Despite ongoing advances in our understanding of UC, its pathogenesis is yet unelucidated, underscoring the urgent need for novel treatment strategies for patients with UC. Exosomes are nanoscale membrane particles that mediate intercellular communication by carrying various bioactive molecules, such as proteins, RNAs, DNA, and metabolites. The NOD-like receptor family pyrin domain containing 3 (NLRP3) inflammasome is a cytosolic tripartite protein complex whose ac...
Source: World Journal of Gastroenterology : WJG - March 11, 2024 Category: Gastroenterology Authors: Xin Li Li-Jiang Ji Kai-Di Feng Hua Huang Mei-Rou Liang Shi-Jin Cheng Xiu-Dong Meng Source Type: research

Preoperative prediction of lymphovascular and perineural invasion in gastric cancer using spectral computed tomography imaging and machine learning
CONCLUSION: The study found that using portal venous and EP spectral CT parameters allows effective preoperative detection of LVI/PNI in GC, with accuracy boosted by integrating clinical markers.PMID:38463023 | PMC:PMC10921149 | DOI:10.3748/wjg.v30.i6.542 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - March 11, 2024 Category: Gastroenterology Authors: Hui-Ting Ge Jian-Wu Chen Li-Li Wang Tian-Xiu Zou Bin Zheng Yuan-Fen Liu Yun-Jing Xue Wei-Wen Lin Source Type: research

Angiotensin-converting enzyme 2 alleviates liver fibrosis through the renin-angiotensin system
World J Gastroenterol. 2024 Feb 14;30(6):607-609. doi: 10.3748/wjg.v30.i6.607.ABSTRACTThe present letter to the editor is related to the study titled 'Angiotensin-converting enzyme 2 improves liver fibrosis in mice by regulating autophagy of hepatic stellate cells'. Angiotensin-converting enzyme 2 can alleviate liver fibrosis by regulating autophagy of hepatic stellate cells and affecting the renin-angiotensin system.PMID:38463024 | PMC:PMC10921144 | DOI:10.3748/wjg.v30.i6.607 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - March 11, 2024 Category: Gastroenterology Authors: Bai-Wei Zhao Ying-Jia Chen Ruo-Peng Zhang Yong-Ming Chen Bo-Wen Huang Source Type: research

Endoscopic intramural cystogastrostomy for treatment of peripancreatic fluid collection: A viewpoint from a surgeon
World J Gastroenterol. 2024 Feb 14;30(6):610-613. doi: 10.3748/wjg.v30.i6.610.ABSTRACTPercutaneous or endoscopic drainage is the initial choice for the treatment of peripancreatic fluid collection in symptomatic patients. Endoscopic transgastric fenestration (ETGF) was first reported for the management of pancreatic pseudocysts of 20 patients in 2008. From a surgeon's viewpoint, ETGF is a similar procedure to cystogastrostomy in that they both produce a wide outlet orifice for the drainage of fluid and necrotic debris. ETGF can be performed at least 4 wk after the initial onset of acute pancreatitis and it has a high prior...
Source: World Journal of Gastroenterology : WJG - March 11, 2024 Category: Gastroenterology Authors: Chen-Guo Ker Source Type: research

Optimized sequential therapy < em > vs < /em > 10- and 14-d concomitant therapy for eradicating < em > Helicobacter pylori < /em > : A randomized clinical trial
CONCLUSION: The optimized 14-d sequential therapy is a safe and effective alternative. Its eradication rate is comparable to that of the 14-d concomitant therapy while causing fewer AEs and allowing a gain in terms of cost.PMID:38463026 | PMC:PMC10921140 | DOI:10.3748/wjg.v30.i6.556 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - March 11, 2024 Category: Gastroenterology Authors: Hassan Seddik Jihane Benass Sanaa Berrag Asmae Sair Reda Berraida Hanae Boutallaka Source Type: research

Unmet needs in biomarkers for autoimmune pancreatitis diagnosis
World J Gastroenterol. 2024 Feb 14;30(6):523-526. doi: 10.3748/wjg.v30.i6.523.ABSTRACTAutoimmune pancreatitis (AIP) is a rare chronic autoimmune disorder. The diagnosis of AIP mainly depends on histopathology, imaging and response to treatment. Serum immunoglobulin 4 (IgG4) is used only as collateral evidence in diagnostic criteria for AIP because of its moderate sensitivity. Serum IgG4 levels are normal in 15%-37% of type 1 AIP and most of type 2 AIP patients. In these patients, the indeterminate imaging and histopathology may lead to the difficulty in definitive diagnosis of AIP. Therefore, discovery of new biomarkers is...
Source: World Journal of Gastroenterology : WJG - March 11, 2024 Category: Gastroenterology Authors: Bao-Can Wang Jian-Gao Fan Source Type: research

Role of deubiquitinase JOSD2 in the pathogenesis of esophageal squamous cell carcinoma
CONCLUSION: JOSD2 plays a crucial role in enhancing the proliferation, migration, and drug resistance of ESCC, suggesting that JOSD2 is a potential therapeutic target in ESCC.PMID:38463028 | PMC:PMC10921146 | DOI:10.3748/wjg.v30.i6.565 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - March 11, 2024 Category: Gastroenterology Authors: Wen-Peng Wang Dan Shi Duo Yun Jun Hu Jie-Fu Wang Jia Liu Yan-Peng Yang Ming-Rui Li Jun-Feng Wang Da-Lu Kong Source Type: research

Urea breath test for < em > Helicobacter pylori < /em > infection in adult dyspeptic patients: A meta-analysis of diagnostic test accuracy
CONCLUSION: In summary, our study has demonstrated that 13C-UBT has been found to outperform the 14C-UBT, making it the preferred diagnostic approach. Additionally, our results emphasize the significance of carefully considering urea dosage, assessment timing, and measurement techniques for both tests to enhance diagnostic precision. Nevertheless, it is crucial for researchers and clinicians to evaluate the strengths and limitations of our findings before implementing them in practice.PMID:38463019 | PMC:PMC10921142 | DOI:10.3748/wjg.v30.i6.579 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - March 11, 2024 Category: Gastroenterology Authors: Fabian Fellipe Bueno Lemos Caroline Tianeze de Castro Marcel Silva Luz Gabriel Reis Rocha Gabriel Lima Correa Santos Lu ís Guilherme de Oliveira Silva Mariana Santos Calmon Cl áudio Lima Souza Ana Carla Zarpelon-Schutz K ádima Nayara Teixeira Dulciene Source Type: research

Y-Z deformable magnetic ring for the treatment of rectal stricture: A case report and review of literature
CONCLUSION: The Y-Z DMR deformable magnetic ring is an excellent treatment strategy for patients with rectal stenosis and without enterostomy.PMID:38463020 | PMC:PMC10921145 | DOI:10.3748/wjg.v30.i6.599 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - March 11, 2024 Category: Gastroenterology Authors: Miao-Miao Zhang Huan-Chen Sha Yuan-Fa Qin Yi Lyu Xiao-Peng Yan Source Type: research

Diagnostic tools for fecal incontinence: Scoring systems are the crucial first step
World J Gastroenterol. 2024 Feb 14;30(6):516-522. doi: 10.3748/wjg.v30.i6.516.ABSTRACTThe main aim of this editorial is to comment on the recent article published by Garg et al in the World Journal of Gastroenterology 2023; 29: 4593-4603. This original research presents a new scoring system for fecal incontinence. Fecal incontinence is a chronic disease with a severe impact on the quality of life of the patients. Substantial social stigmatization often leads to significant underreporting of the condition even during visits to a specialist and could lead to further mismanagement or non-existent management of the disease. An...
Source: World Journal of Gastroenterology : WJG - March 11, 2024 Category: Gastroenterology Authors: Peter Liptak Martin Duricek Peter Banovcin Source Type: research

Emerging role of exosomes in ulcerative colitis: Targeting NOD-like receptor family pyrin domain containing 3 inflammasome
World J Gastroenterol. 2024 Feb 14;30(6):527-541. doi: 10.3748/wjg.v30.i6.527.ABSTRACTUlcerative colitis (UC) is a chronic recurrent inflammatory bowel disease. Despite ongoing advances in our understanding of UC, its pathogenesis is yet unelucidated, underscoring the urgent need for novel treatment strategies for patients with UC. Exosomes are nanoscale membrane particles that mediate intercellular communication by carrying various bioactive molecules, such as proteins, RNAs, DNA, and metabolites. The NOD-like receptor family pyrin domain containing 3 (NLRP3) inflammasome is a cytosolic tripartite protein complex whose ac...
Source: World Journal of Gastroenterology : WJG - March 11, 2024 Category: Gastroenterology Authors: Xin Li Li-Jiang Ji Kai-Di Feng Hua Huang Mei-Rou Liang Shi-Jin Cheng Xiu-Dong Meng Source Type: research

Preoperative prediction of lymphovascular and perineural invasion in gastric cancer using spectral computed tomography imaging and machine learning
CONCLUSION: The study found that using portal venous and EP spectral CT parameters allows effective preoperative detection of LVI/PNI in GC, with accuracy boosted by integrating clinical markers.PMID:38463023 | PMC:PMC10921149 | DOI:10.3748/wjg.v30.i6.542 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - March 11, 2024 Category: Gastroenterology Authors: Hui-Ting Ge Jian-Wu Chen Li-Li Wang Tian-Xiu Zou Bin Zheng Yuan-Fen Liu Yun-Jing Xue Wei-Wen Lin Source Type: research