World Journal of Gastroenterology : WJG This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Alkaline sphingomyelinase deficiency impairs intestinal mucosal barrier integrity and reduces antioxidant capacity in dextran sulfate sodium-induced colitis
CONCLUSION: Alk-SMase regulates the stability of the intestinal mucosal barrier and enhances antioxidant activity through the Nrf2 signaling pathway.PMID:38596488 | PMC:PMC11000083 | DOI:10.3748/wjg.v30.i10.1405 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - April 10, 2024 Category: Gastroenterology Authors: Ye Tian Xin Li Xu Wang Si-Ting Pei Hong-Xin Pan Yu-Qi Cheng Yi-Chen Li Wen-Ting Cao Jin-Dong Ding Petersen Ping Zhang Source Type: research

Are we ready to use new endoscopic scores for ulcerative colitis?
World J Gastroenterol. 2024 Mar 14;30(10):1466-1469. doi: 10.3748/wjg.v30.i10.1466.ABSTRACTFor ulcerative colitis (UC), the variability in inflammatory activity along the colon poses a challenge in management. The focus on achieving endoscopic healing in UC is evident, where the UC Endoscopic Index of Severity and Mayo Endoscopic Subscore are commonly used for evaluation. However, these indices primarily consider the most severely affected region. Liu et al recent study validates the Toronto Inflammatory Bowel Disease Global Endoscopic Reporting (TIGER) score offering a comprehensive assessment of inflammatory activity acr...
Source: World Journal of Gastroenterology : WJG - April 10, 2024 Category: Gastroenterology Authors: Rodrigo Quera Paulina N úñez F Source Type: research

Nomograms and prognosis for superficial esophageal squamous cell carcinoma
World J Gastroenterol. 2024 Mar 14;30(10):1291-1294. doi: 10.3748/wjg.v30.i10.1291.ABSTRACTIn recent years, endoscopic resection, particularly endoscopic submucosal dissection, has become increasingly popular in treating non-metastatic superficial esophageal squamous cell carcinoma (ESCC). In this evolving paradigm, it is crucial to identify factors that predict higher rates of lymphatic invasion and poorer outcomes. Larger tumor size, deeper invasion, poorer differentiation, more infiltrative growth patterns (INF-c), higher-grade tumor budding, positive lymphovascular invasion, and certain biomarkers have been associated ...
Source: World Journal of Gastroenterology : WJG - April 10, 2024 Category: Gastroenterology Authors: Hong Tao Lin Ahmed Abdelbaki Somashekar G Krishna Source Type: research

Women health and microbiota: Different aspects of well-being
World J Gastroenterol. 2024 Mar 14;30(10):1287-1290. doi: 10.3748/wjg.v30.i10.1287.ABSTRACTIn this editorial, we comment on the article by Marano et al recently published in the World Journal of Gastroenterology 2023; 29 (45): 5945-5952. We focus on the role of gut microbiota (GM) in women's health, highlighting the need to thoroughly comprehend the sex differences in microbiota. Together, the host and GM support the host's health. The microbiota components consist of viruses, bacteria, fungi, and archaea. This complex is an essential part of the host and is involved in neurological development, metabolic control, immune s...
Source: World Journal of Gastroenterology : WJG - April 10, 2024 Category: Gastroenterology Authors: Giulia Nannini Amedeo Amedei Source Type: research

Double role of depression in gastric cancer: As a causative factor and as consequence
World J Gastroenterol. 2024 Mar 14;30(10):1266-1269. doi: 10.3748/wjg.v30.i10.1266.ABSTRACTIn this editorial we comment on the article "Hotspots and frontiers of the relationship between gastric cancer and depression: A bibliometric study". Gastric cancer (GC) is a common malignancy in the digestive system with increased mortality and morbidity rates globally. Standard treatments, such as gastrectomy, negatively impact patients' quality of life and beyond the physical strain, GC patients face psychological challenges, including anxiety and depression. The prevalence of depression can be as high as 57%, among gastrointestin...
Source: World Journal of Gastroenterology : WJG - April 10, 2024 Category: Gastroenterology Authors: Grigorios Christodoulidis Koumarelas Konstantinos-Eleftherios Kouliou Marina-Nektaria Source Type: research

Overview of the immunological mechanisms in hepatitis B virus reactivation: Implications for disease progression and management strategies
In conclusion, this comprehensive review furnishes a holistic view of the immunological mechanisms that propel HBV reactivation. With a dedicated focus on understanding its implications for disease progression and the prospects of efficient management strategies, this article contributes significantly to the knowledge base. The more profound insights into the intricate interactions between viral elements and the immune system will inform evidence-based approaches, ultimately enhancing disease management and elevating patient outcomes. The dynamic landscape of management strategies is critically scrutinized, spanning anti-v...
Source: World Journal of Gastroenterology : WJG - April 10, 2024 Category: Gastroenterology Authors: Hui Ma Qing-Zhu Yan Jing-Ru Ma Dong-Fu Li Jun-Ling Yang Source Type: research

Stage at diagnosis of colorectal cancer through diagnostic route: Who should be screened?
CONCLUSION: CRCs detected during hospital visits for comorbidities were diagnosed earlier, similar to cancer screening. CRC screening should be recommended, particularly for patients without periodical hospital visits for comorbidities.PMID:38596494 | PMC:PMC11000077 | DOI:10.3748/wjg.v30.i10.1368 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - April 10, 2024 Category: Gastroenterology Authors: Nobukazu Agatsuma Takahiro Utsumi Yoshitaka Nishikawa Takahiro Horimatsu Takeshi Seta Yukitaka Yamashita Yukari Tanaka Takahiro Inoue Yuki Nakanishi Takahiro Shimizu Mikako Ohno Akane Fukushima Takeo Nakayama Hiroshi Seno Source Type: research

Vonoprazan-amoxicillin dual regimen with < em > Saccharomyces boulardii < /em > as a rescue therapy for < em > Helicobacter pylori < /em > : Current perspectives and implications
World J Gastroenterol. 2024 Mar 14;30(10):1280-1286. doi: 10.3748/wjg.v30.i10.1280.ABSTRACTYu et al's study in the World Journal of Gastroenterology (2023) introduced a novel regimen of Vonoprazan-amoxicillin dual therapy combined with Saccharomyces boulardii (S. boulardii) for the rescue therapy against Helicobacter pylori (H. pylori), a pathogen responsible for peptic ulcers and gastric cancer. Vonoprazan is a potassium-competitive acid blocker renowned for its rapid and long-lasting acid suppression, which is minimally affected by mealtime. Compared to proton pump inhibitors, which bind irreversibly to cysteine residues...
Source: World Journal of Gastroenterology : WJG - April 10, 2024 Category: Gastroenterology Authors: Valerie Josephine Dirjayanto Jessica Audrey Daniel Martin Simadibrata Source Type: research

Preliminary exploration of animal models of congenital choledochal cysts
CONCLUSION: The model of partial ligation of the bile duct of juvenile rats could morphologically simulate the cystic or fusiform CC, which may contribute to investigating the pathogenesis of CC.PMID:38596496 | PMC:PMC11000093 | DOI:10.3748/wjg.v30.i10.1420 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - April 10, 2024 Category: Gastroenterology Authors: Shu-Hao Zhang Yue-Bin Zhang Duo-Te Cai Tao Pan Ken Chen Yi Jin Wen-Juan Luo Zong-Wei Huang Qing-Jiang Chen Zhi-Gang Gao Source Type: research

Time trends and outcomes of gastrostomy placement in a Swedish national cohort over two decades
CONCLUSION: The annual use of gastrostomies in Sweden increased during the study period, with a shift towards more minimally invasive procedures. Although procedure-related death was rare, the overall 30-d mortality rate was high (10%). To overcome this, we believe that patient selection should be improved.PMID:38596497 | PMC:PMC11000080 | DOI:10.3748/wjg.v30.i10.1358 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - April 10, 2024 Category: Gastroenterology Authors: Martin L öfling Skogar Magnus Sundbom Source Type: research

Optimizing nutrition in hepatic cirrhosis: A comprehensive assessment and care approach
World J Gastroenterol. 2024 Mar 14;30(10):1313-1328. doi: 10.3748/wjg.v30.i10.1313.ABSTRACTCirrhosis is considered a growing cause of morbidity and mortality, which represents a significant public health problem. Currently, there is no effective treatment to reverse cirrhosis. Treatment primarily centers on addressing the underlying liver condition, monitoring, and managing portal hypertension-related complications, and evaluating the potential for liver transplantation in cases of decompensated cirrhosis, marked by rapid progression and the emergence of complications like variceal bleeding, hepatic encephalopathy, ascites...
Source: World Journal of Gastroenterology : WJG - April 10, 2024 Category: Gastroenterology Authors: Osvely Mendez-Guerrero Anaisa Carranza-Carrasco Luis Alberto Chi-Cervera Aldo Torre Nalu Navarro-Alvarez Source Type: research

Establishment and validation of an adherence prediction system for lifestyle interventions in non-alcoholic fatty liver disease
CONCLUSION: The EDAS can reliably assess the adherence of patients with NAFLD to lifestyle interventions and have clinical application in this population.PMID:38596499 | PMC:PMC11000086 | DOI:10.3748/wjg.v30.i10.1393 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - April 10, 2024 Category: Gastroenterology Authors: Ming-Hui Zeng Qi-Yu Shi Liang Xu Yu-Qiang Mi Source Type: research

Differential diagnosis of Crohn's disease and intestinal tuberculosis based on ATR-FTIR spectroscopy combined with machine learning
CONCLUSION: Information on the mid-infrared region can reveal the different histological components of CD and ITB at the molecular level, and spectral analysis combined with machine learning to establish a diagnostic model is expected to become a new method for the differential diagnosis of CD and ITB.PMID:38596500 | PMC:PMC11000079 | DOI:10.3748/wjg.v30.i10.1377 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - April 10, 2024 Category: Gastroenterology Authors: Yuan-Peng Li Tian-Yu Lu Fu-Rong Huang Wei-Min Zhang Zhen-Qiang Chen Pei-Wen Guang Liang-Yu Deng Xin-Hao Yang Source Type: research

Capsule endoscopy and panendoscopy: A journey to the future of gastrointestinal endoscopy
World J Gastroenterol. 2024 Mar 14;30(10):1270-1279. doi: 10.3748/wjg.v30.i10.1270.ABSTRACTIn 2000, the small bowel capsule revolutionized the management of patients with small bowel disorders. Currently, the technological development achieved by the new models of double-headed endoscopic capsules, as miniaturized devices to evaluate the small bowel and colon [pan-intestinal capsule endoscopy (PCE)], makes this non-invasive procedure a disruptive concept for the management of patients with digestive disorders. This technology is expected to identify which patients will require conventional invasive endoscopic procedures (c...
Source: World Journal of Gastroenterology : WJG - April 10, 2024 Category: Gastroenterology Authors: Bruno Rosa Jos é Cotter Source Type: research

Shear-wave elastography to predict hepatocellular carcinoma after hepatitis C virus eradication: A systematic review and meta-analysis
CONCLUSION: SWE could be a promising tool for prediction of HCC occurrence in patients treated with DAAs. Further studies with larger cohorts and standardized timing of elastographic evaluation are needed to confirm these data.PMID:38596502 | PMC:PMC11000078 | DOI:10.3748/wjg.v30.i10.1450 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - April 10, 2024 Category: Gastroenterology Authors: Giorgio Esposto Paolo Santini Linda Galasso Irene Mignini Maria Elena Ainora Antonio Gasbarrini Maria Assunta Zocco Source Type: research