Applying the Lessons of Influenza to Coronavirus During a Time of Uncertainty.
PMID: 32208975 [PubMed - as supplied by publisher] (Source: Circulation)
Source: Circulation - March 25, 2020 Category: Cardiology Authors: Vardeny O, Madjid M, Solomon SD Tags: Circulation Source Type: research

Critical Organizational Issues for Cardiologists in the COVID-19 Outbreak: A Frontline Experience From Milan, Italy.
PMID: 32207994 [PubMed - as supplied by publisher] (Source: Circulation)
Source: Circulation - March 24, 2020 Category: Cardiology Authors: Stefanini GG, Azzolini E, Condorelli G Tags: Circulation Source Type: research

Letter by Rivasi et al Regarding Article, "Effects of Intensive Versus Standard Ambulatory Blood Pressure Control on Cerebrovascular Outcomes in Older People (INFINITY)".
Letter by Rivasi et al Regarding Article, "Effects of Intensive Versus Standard Ambulatory Blood Pressure Control on Cerebrovascular Outcomes in Older People (INFINITY)". Circulation. 2020 Mar 24;141(12):e650-e651 Authors: Rivasi G, Mossello E, Ungar A PMID: 32202932 [PubMed - in process] (Source: Circulation)
Source: Circulation - March 24, 2020 Category: Cardiology Authors: Rivasi G, Mossello E, Ungar A Tags: Circulation Source Type: research

Cardiac Cell Therapy Rejuvenates the Infarcted Rodent Heart via Direct Injection but Not by Vascular Infusion.
PMID: 32202933 [PubMed - in process] (Source: Circulation)
Source: Circulation - March 24, 2020 Category: Cardiology Authors: Vagnozzi RJ, Sargent MA, Molkentin JD Tags: Circulation Source Type: research

Two Sides of the Same Coin in Myotonic Dystrophy Type 1.
lin G PMID: 32202934 [PubMed - in process] (Source: Circulation)
Source: Circulation - March 24, 2020 Category: Cardiology Authors: Arias MA, Pachón M, Loughlin G Tags: Circulation Source Type: research

Impact of Low-Flow Duration on Favorable Neurological Outcomes of Extracorporeal Cardiopulmonary Resuscitation After Out-of-Hospital Cardiac Arrest: A Multicenter Prospective Study.
B, Iwami T, Kitamura T, CRITICAL Study Group Investigators PMID: 32202935 [PubMed - in process] (Source: Circulation)
Source: Circulation - March 24, 2020 Category: Cardiology Authors: Matsuyama T, Irisawa T, Yamada T, Hayakawa K, Yoshiya K, Noguchi K, Nishimura T, Ishibe T, Yagi Y, Kiguchi T, Kishimoto M, Shintani H, Hayashi Y, Sogabe T, Morooka T, Sakamoto H, Suzuki K, Nakamura F, Nishioka N, Okada Y, Matsui S, Sado J, Shimazu T, Ohta Tags: Circulation Source Type: research

Research Priorities for Heart Failure With Preserved Ejection Fraction: National Heart, Lung, and Blood Institute Working Group Summary.
Abstract Heart failure with preserved ejection fraction (HFpEF), a major public health problem that is rising in prevalence, is associated with high morbidity and mortality and is considered to be the greatest unmet need in cardiovascular medicine today because of a general lack of effective treatments. To address this challenging syndrome, the National Heart, Lung, and Blood Institute convened a working group made up of experts in HFpEF and novel research methodologies to discuss research gaps and to prioritize research directions over the next decade. Here, we summarize the discussion of the working group, follo...
Source: Circulation - March 24, 2020 Category: Cardiology Authors: Shah SJ, Borlaug BA, Kitzman DW, McCulloch AD, Blaxall BC, Agarwal R, Chirinos JA, Collins S, Deo RC, Gladwin MT, Granzier H, Hummel SL, Kass DA, Redfield MM, Sam F, Wang TJ, Desvigne-Nickens P, Adhikari BB Tags: Circulation Source Type: research

Response to Letter Regarding Article, "Effects of Intensive Versus Standard Ambulatory Blood Pressure Control on Cerebrovascular Outcomes in Older People (INFINITY)".
Response to Letter Regarding Article, "Effects of Intensive Versus Standard Ambulatory Blood Pressure Control on Cerebrovascular Outcomes in Older People (INFINITY)". Circulation. 2020 Mar 24;141(12):e652-e653 Authors: White WB, Wolfson L PMID: 32202937 [PubMed - in process] (Source: Circulation)
Source: Circulation - March 24, 2020 Category: Cardiology Authors: White WB, Wolfson L Tags: Circulation Source Type: research

Variation in Ultrasound Diagnostic Thresholds for Carotid Stenosis in the United States.
PMID: 32202938 [PubMed - in process] (Source: Circulation)
Source: Circulation - March 24, 2020 Category: Cardiology Authors: Kim ESH, Zierler RE Tags: Circulation Source Type: research

Branched-Chain Amino Acid Catabolism Promotes Thrombosis Risk by Enhancing Tropomodulin-3 Propionylation in Platelets.
Abstract Background: Branched-chain amino acids (BCAAs), essential nutrients including leucine, isoleucine and valine, serve as a resource for energy production and the regulator of important nutrient and metabolic signals. Recent studies have suggested that dysfunction of BCAA catabolism is associated with a risk of cardiovascular disease. Platelets play an important role in cardiovascular disease, but the functions of BCAA catabolism in platelets remain unknown. Methods: The activity of human platelets from healthy subjects before and after ingestion of BCAAs were measured. Protein phosphatase 2Cm (PP2Cm) specif...
Source: Circulation - March 23, 2020 Category: Cardiology Authors: Xu Y, Jiang H, Li L, Chen F, Liu Y, Zhou M, Wang J, Jiang J, Li X, Fan X, Zhang L, Zhang J, Qiu J, Wu Y, Fang C, Sun H, Liu J Tags: Circulation Source Type: research

Isoflavone Intake and the Risk of Coronary Heart Disease in US Men and Women: Results From 3 Prospective Cohort Studies.
PMID: 32200662 [PubMed - as supplied by publisher] (Source: Circulation)
Source: Circulation - March 23, 2020 Category: Cardiology Authors: Ma L, Liu G, Ding M, Zong G, Hu FB, Willett WC, Rimm EB, Manson JE, Sun Q Tags: Circulation Source Type: research

Coronavirus Disease 2019 (COVID-19) and Cardiovascular Disease.
PMID: 32200663 [PubMed - as supplied by publisher] (Source: Circulation)
Source: Circulation - March 21, 2020 Category: Cardiology Authors: Clerkin KJ, Fried JA, Raikhelkar J, Sayer G, Griffin JM, Masoumi A, Jain SS, Burkhoff D, Kumaraiah D, Rabbani L, Schwartz A, Uriel N Tags: Circulation Source Type: research

Science in a Time of Crisis.
PMID: 32200665 [PubMed - as supplied by publisher] (Source: Circulation)
Source: Circulation - March 21, 2020 Category: Cardiology Authors: Hill JA, McGuire DK, de Lemos JA Tags: Circulation Source Type: research

Novel Mutations and Decreased Expression of the Epigenetic Regulator TET2 in Pulmonary Arterial Hypertension.
Conclusions: PAH is the first human disease related to potential TET2 germline mutations. Inherited and acquired abnormalities of TET2 occur in 0.39% of PAH cases. Decreased TET2 expression is ubiquitous and has potential as a PAH biomarker. PMID: 32192357 [PubMed - as supplied by publisher] (Source: Circulation)
Source: Circulation - March 20, 2020 Category: Cardiology Authors: Potus F, Pauciulo MW, Cook EK, Zhu N, Hsieh A, Welch CL, Shen Y, Tian L, Lima P, Mewburn J, D'Arsigny CL, Lutz KA, Coleman AW, Damico R, Snetsinger B, Martin AY, Hassoun PM, Nichols WC, Chung WK, Rauh MJ, Archer SL Tags: Circulation Source Type: research

Reducing Hypermuscularization of the Transitional Segment between Arterioles and Capillaries Protects Against Spontaneous Intracerebral Hemorrhage.
Conclusions: Our results suggest that hypermuscularization of the TS, via increased Notch3 activity, is involved in the occurrence of ICH in Col4a1 mutant mice, by raising the intravascular pressure in the upstream feeding arteriole and promoting its rupture at the site of SMC loss. Our human data indicate that these 2 mutually reinforcing vascular defects may represent a general mechanism of deep ICH. PMID: 32183562 [PubMed - as supplied by publisher] (Source: Circulation)
Source: Circulation - March 18, 2020 Category: Cardiology Authors: Ratelade J, Klug NR, Lombardi D, Angelim MKSC, Dabertrand F, Domenga-Denier V, Al-Shahi Salman R, Smith C, Gerbeau JF, Nelson MT, Joutel A Tags: Circulation Source Type: research

Rivaroxaban Plus Aspirin Versus Aspirin Alone in Patients with Prior Percutaneous Coronary Intervention (COMPASS-PCI).
Conclusions: DPI compared with aspirin produced consistent reductions in MACE and mortality but with increased major bleeding with or without prior PCI. Among those with prior PCI one- year and beyond, effects on MACE and mortality were consistent irrespective of time since last PCI. Clinical Trial Registration: URL: www.ClinicalTrials.gov Unique Identifier: NCT01776424. PMID: 32178526 [PubMed - as supplied by publisher] (Source: Circulation)
Source: Circulation - March 17, 2020 Category: Cardiology Authors: Bainey KR, Welsh RC, Connolly SJ, Marsden T, Bosch J, Fox KAA, Steg PG, Vinereanu D, Connolly DL, Berkowitz SD, Foody JM, Probstfield JL, Branch KR, Lewis BS, Diaz R, Muehlhofer E, Widimsky P, Yusuf S, Eikelboom JW, Bhatt DL, COMPASS Investigators Tags: Circulation Source Type: research

Role of the American Heart Association in the Global COVID-19 Pandemic.
PMID: 32181680 [PubMed - as supplied by publisher] (Source: Circulation)
Source: Circulation - March 17, 2020 Category: Cardiology Authors: Elkind MS, Harrington RA, Benjamin IJ Tags: Circulation Source Type: research

Extracorporeal Cardiopulmonary Resuscitation for Adults With Refractory Out-of-Hospital Cardiac Arrest: Towards Better Neurological Outcomes.
PMID: 32176540 [PubMed - in process] (Source: Circulation)
Source: Circulation - March 17, 2020 Category: Cardiology Authors: Sonneville R, Schmidt M Tags: Circulation Source Type: research

Trends in Antiarrhythmic Drug Use Among Patients in the United States Between 2004 and 2016.
PMID: 32176541 [PubMed - in process] (Source: Circulation)
Source: Circulation - March 17, 2020 Category: Cardiology Authors: Markman TM, Geng Z, Epstein AE, Nazarian S, Deo R, Marchlinski FE, Groeneveld PW, Frankel DS Tags: Circulation Source Type: research

Identifying the Cardiac Dyad Proteome In Vivo by a BioID2 Knock-In Strategy.
PMID: 32176542 [PubMed - in process] (Source: Circulation)
Source: Circulation - March 17, 2020 Category: Cardiology Authors: Feng W, Liu C, Spinozzi S, Wang L, Evans SM, Chen J Tags: Circulation Source Type: research

New Onset Recurrent Syncope Triggered by Fever.
lin G PMID: 32176543 [PubMed - in process] (Source: Circulation)
Source: Circulation - March 17, 2020 Category: Cardiology Authors: Arias MA, Pachón M, Loughlin G Tags: Circulation Source Type: research

Response by Schrage et al to Letter Regarding Article, "Association Between Use of Primary-Prevention Implantable Cardioverter-Defibrillators and Mortality in Patients With Heart Failure: A Prospective Propensity Score-Matched Analysis From the Swedish Heart Failure Registry".
Response by Schrage et al to Letter Regarding Article, "Association Between Use of Primary-Prevention Implantable Cardioverter-Defibrillators and Mortality in Patients With Heart Failure: A Prospective Propensity Score-Matched Analysis From the Swedish Heart Failure Registry". Circulation. 2020 Mar 17;141(11):e648-e649 Authors: Schrage B, Linde C, Braunschweig F, Savarese G PMID: 32176544 [PubMed - in process] (Source: Circulation)
Source: Circulation - March 17, 2020 Category: Cardiology Authors: Schrage B, Linde C, Braunschweig F, Savarese G Tags: Circulation Source Type: research

Letter by Littmann Regarding Article, "Association Between Use of Primary-Prevention Implantable Cardioverter-Defibrillators and Mortality in Patients With Heart Failure: A Prospective Propensity Score-Matched Analysis From the Swedish Heart Failure Registry".
Letter by Littmann Regarding Article, "Association Between Use of Primary-Prevention Implantable Cardioverter-Defibrillators and Mortality in Patients With Heart Failure: A Prospective Propensity Score-Matched Analysis From the Swedish Heart Failure Registry". Circulation. 2020 Mar 17;141(11):e646-e647 Authors: Littmann L PMID: 32176545 [PubMed - in process] (Source: Circulation)
Source: Circulation - March 17, 2020 Category: Cardiology Authors: Littmann L Tags: Circulation Source Type: research

Low-Attenuation Noncalcified Plaque on Coronary Computed Tomography Angiography Predicts Myocardial Infarction: Results From the Multicenter SCOT-HEART Trial (Scottish Computed Tomography of the HEART).
, Newby DE, Dweck MR, Dey D PMID: 32174130 [PubMed - as supplied by publisher] (Source: Circulation)
Source: Circulation - March 16, 2020 Category: Cardiology Authors: Williams MC, Kwiecinski J, Doris M, McElhinney P, D'Souza MS, Cadet S, Adamson PD, Moss AJ, Alam S, Hunter A, Shah ASV, Mills NL, Pawade T, Wang C, Weir McCall J, Bonnici-Mallia M, Murrills C, Roditi G, van Beek EJR, Shaw LJ, Nicol ED, Berman DS, Slomka P Tags: Circulation Source Type: research

Role of Deranged Energy Deprivation Signaling in the Pathogenesis of Cardiac and Renal Disease in States of Perceived Nutrient Overabundance.
Abstract Sodium-glucose cotransporter 2 inhibitors reduce the risk of serious heart failure and adverse renal events, but the mechanisms that underlie this benefit are not understood. Treatment with SGLT2 inhibitors is distinguished by two intriguing features - ketogenesis and erythrocytosis. Both reflect the induction of a fasting-like and hypoxia-like transcriptional paradigm that is capable of restoring and maintaining cellular homeostasis and survival. In the face of perceived nutrient and oxygen deprivation, cells activate low-energy sensors, which include sirtuin-1 (SIRT1), adenosine monophosphate-activated ...
Source: Circulation - March 13, 2020 Category: Cardiology Authors: Packer M Tags: Circulation Source Type: research

Heart-Specific Immune Responses in an Animal Model of AutoimmuneRelated Myocarditis Mitigated by an Immunoproteasome Inhibitor and Genetic Ablation.
Conclusions: By reversing heart-specific autoimmune responses, immunoproteasome inhibitors applied to a mouse model demonstrate their potential to aid in the management of autoimmune myocarditis in humans, possibly including cases with ICI-related heart-specific autoimmunity. PMID: 32160764 [PubMed - as supplied by publisher] (Source: Circulation)
Source: Circulation - March 12, 2020 Category: Cardiology Authors: Bockstahler M, Fischer A, Goetzke CC, Neumaier HL, Sauter M, Kespohl M, Müller AM, Meckes C, Salbach C, Schenk M, Heuser A, Landmesser U, Weiner J, Meder B, Lehmann L, Kratzer A, Klingel K, Katus HA, Kaya Z, Beling A Tags: Circulation Source Type: research

Apixaban versus Warfarin in Patients with Atrial Fibrillation and Advanced Chronic Kidney Disease.
Conclusions: Among patients with AF and CrCl 25-30 mL/min, apixaban caused less bleeding than warfarin, with even greater reductions in bleeding than in patients with CrCl>30 mL/min. We observed substantial overlap in the range of exposure to apixaban 5 mg twice daily for patients with or without advanced CKD, supporting conventional dosing in patients with CrCl 25-30 mL/min. Randomized controlled studies evaluating the safety and efficacy of apixaban are urgently needed in patients with advanced CKD, including those receiving dialysis. Clinical Trial Registration: URL: https://ClinicalTrials.gov Unique Identifier: NCT0...
Source: Circulation - March 12, 2020 Category: Cardiology Authors: Stanifer JW, Pokorney SD, Chertow GM, Hohnloser SH, Wojdyla DM, Garonzik S, Byon W, Hijazi Z, Lopes RD, Alexander JH, Wallentin L, Granger CB Tags: Circulation Source Type: research

Suicide Attempts Among LVAD Recipients: Real-Life Data From the ASSIST-ICD Study.
tzler PY, Anselme F, Babatasi G, Belin A, Garnier F, Bielefeld M, Hamon D, Lellouche N, Bourguignon T, Genet T, Eschalier R, D'Ostrevy N, Bories MC, Jouan J, Vanhuyse F, Blangy H, Doucerain J, Martins RP, Galand V PMID: 32153210 [PubMed - as supplied by publisher] (Source: Circulation)
Source: Circulation - March 10, 2020 Category: Cardiology Authors: Charton M, Flécher E, Leclercq C, Delmas C, Dambrin C, Goeminne C, Vincentelli A, Michel M, Lehelias L, Verdonk C, Para M, Pozzi M, Obadia JF, Boignard A, Chavanon O, Barandon L, Nubret K, Kindo M, Minh TH, Gaudard P, Pelcé E, Gariboldi V, Litzler PY, A Tags: Circulation Source Type: research

Loss of Filamin C Is Catastrophic for Heart Function.
PMID: 32150467 [PubMed - in process] (Source: Circulation)
Source: Circulation - March 10, 2020 Category: Cardiology Authors: Zhou Y, Chen Z, Zhang L, Zhu M, Tan C, Zhou X, Evans SM, Fang X, Feng W, Chen J Tags: Circulation Source Type: research

An Irregular Tachycardia Not Responsive to Medical Treatment: What Is the Diagnosis?
PMID: 32150468 [PubMed - in process] (Source: Circulation)
Source: Circulation - March 10, 2020 Category: Cardiology Authors: Margulescu AD, Thomas DE Tags: Circulation Source Type: research

From CANTOS to CIRT to COLCOT to Clinic: Will All Atherosclerosis Patients Soon Be Treated With Combination Lipid-Lowering and Inflammation-Inhibiting Agents?
PMID: 32150469 [PubMed - in process] (Source: Circulation)
Source: Circulation - March 10, 2020 Category: Cardiology Authors: Ridker PM Tags: Circulation Source Type: research

Characterization of Endovascular Abdominal Aortic Aneurysm Repair Surveillance in the Vascular Quality Initiative.
PMID: 32150470 [PubMed - in process] (Source: Circulation)
Source: Circulation - March 10, 2020 Category: Cardiology Authors: Wanken ZJ, Trooboff SW, Gladders B, Columbo JA, Ramkumar N, Austin AM, Stone DH, Mell MW, Sedrakyan A, Goodney PP Tags: Circulation Source Type: research

Reducing the Risk of Cardiovascular Disease: Brick by BRICS.
PMID: 32150471 [PubMed - in process] (Source: Circulation)
Source: Circulation - March 10, 2020 Category: Cardiology Authors: Reddy KS, Prabhakaran D Tags: Circulation Source Type: research

Correction to: Myosin Sequestration Regulates Sarcomere Function, Cardiomyocyte Energetics, and Metabolism, Informing the Pathogenesis of Hypertrophic Cardiomyopathy.
Authors: PMID: 32150472 [PubMed - in process] (Source: Circulation)
Source: Circulation - March 10, 2020 Category: Cardiology Tags: Circulation Source Type: research

Letter by Cao et al Regarding Article, "Stroke Risk as a Function of Atrial Fibrillation Duration and CHA2DS2-VASc Score".
Letter by Cao et al Regarding Article, "Stroke Risk as a Function of Atrial Fibrillation Duration and CHA2DS2-VASc Score". Circulation. 2020 Mar 10;141(10):e597-e598 Authors: Cao S, Zhu X, Xia M PMID: 32150473 [PubMed - in process] (Source: Circulation)
Source: Circulation - March 10, 2020 Category: Cardiology Authors: Cao S, Zhu X, Xia M Tags: Circulation Source Type: research

Response by Kaplan et al to Letter Regarding Article, "Stroke Risk as a Function of Atrial Fibrillation Duration and CHA2DS2-VASc Score".
Response by Kaplan et al to Letter Regarding Article, "Stroke Risk as a Function of Atrial Fibrillation Duration and CHA2DS2-VASc Score". Circulation. 2020 Mar 10;141(10):e599-e600 Authors: Kaplan RM, Ziegler PD, Passman RS PMID: 32150474 [PubMed - in process] (Source: Circulation)
Source: Circulation - March 10, 2020 Category: Cardiology Authors: Kaplan RM, Ziegler PD, Passman RS Tags: Circulation Source Type: research

White Blood Cells and Blood Pressure: A Mendelian Randomization Study.
Abstract Background: High blood pressure (BP) is a risk factor for cardiovascular morbidity and mortality. While BP is regulated by the function of kidney, vasculature and sympathetic nervous system, recent experimental data suggest that immune cells may play a role in hypertension. Methods: We studied the relationship between major white blood cell types and blood pressure in the UK Biobank population and employed Mendelian randomization (MR) analyses using the ∼750,000 UK-Biobank/International Consortium of Blood Pressure-Genome-Wide Association Studies to examine which leukocyte populations may be causally ...
Source: Circulation - March 9, 2020 Category: Cardiology Authors: Siedlinski M, Jozefczuk E, Xu X, Teumer A, Evangelou E, Schnabel RB, Welsh P, Maffia P, Erdmann J, Tomaszewski M, Caulfield MJ, Sattar N, Holmes MV, Guzik TJ Tags: Circulation Source Type: research

Lifestyle and Risk Factor Modification for Reduction of Atrial Fibrillation: A Scientific Statement From the American Heart Association.
mmittee of the Council on Clinical Cardiology; Council on Arteriosclerosis, Thrombosis and Vascular Biology; Council on Cardiovascular and Stroke Nursing; and Council on Lifestyle and Cardiometabolic Health Abstract Atrial fibrillation (AF), the most common sustained cardiac arrhythmia, is associated with substantial morbidity, mortality, and healthcare use. Great strides have been made in stroke prevention and rhythm control strategies, yet reducing the incidence of AF has been slowed by the increasing incidence and prevalence of AF risk factors, including obesity, physical inactivity, sleep apnea, diabetes melli...
Source: Circulation - March 9, 2020 Category: Cardiology Authors: Chung MK, Eckhardt LL, Chen LY, Ahmed HM, Gopinathannair R, Joglar JA, Noseworthy PA, Pack QR, Sanders P, Trulock KM, American Heart Association Electrocardiography and Arrhythmias Committee and Exercise, Cardiac Rehabilitation, and Secondary Prevention C Tags: Circulation Source Type: research

Myocardial Energetics in Obesity: Enhanced ATP Delivery Through Creatine Kinase with Blunted Stress Response.
Abstract Background: Obesity is strongly associated with exercise intolerance and development of heart failure. While myocardial energetics and diastolic function are impaired in obesity, systolic function is usually preserved. This suggests that the rate of ATP delivery is maintained, but this has never been explored in human obesity. We hypothesised that ATP transfer rate through creatine kinase (CK) (kf CKrest) would be increased, compensating for depleted energy stores (PCr/ATP), but potentially limiting greater ATP delivery during increased workload. We hypothesised these changes would normalise with weight l...
Source: Circulation - March 6, 2020 Category: Cardiology Authors: Rayner JJ, Peterzan MA, Watson WD, Clarke WT, Neubauer S, Rodgers CT, Rider OJ Tags: Circulation Source Type: research

Association of Intensive Lifestyle Intervention, Fitness and Body Mass Index with Risk of Heart Failure in Overweight or Obese Adults with Type 2 Diabetes Mellitus: An Analysis from the Look AHEAD Trial.
Conclusions: Among participants with T2DM in the Look AHEAD trial, the ILI did not appear to modify the risk of HF. Higher baseline CRF and sustained improvements in CRF and weight loss were associated with lower risk of HF. Clinical Trial Registration: URL: https://www.clinicaltrials.gov Unique identifier: NCT00017953. PMID: 32134326 [PubMed - as supplied by publisher] (Source: Circulation)
Source: Circulation - March 5, 2020 Category: Cardiology Authors: Pandey A, Patel KV, Bahnson JL, Gaussoin SA, Martin CK, Balasubramanyam A, Johnson KC, McGuire DK, Bertoni AG, Kitzman D, Berry JD, Look AHEAD research group Tags: Circulation Source Type: research

Integrin β1D Deficiency-Mediated RyR2 Dysfunction Contributes to Catecholamine-Sensitive Ventricular Tachycardia in ARVC.
Conclusions: Our data suggest that integrin β1D deficiency represents a novel mechanism underlying the increased risk of ventricular arrhythmias in patients with ARVC. PMID: 32122157 [PubMed - as supplied by publisher] (Source: Circulation)
Source: Circulation - March 3, 2020 Category: Cardiology Authors: Wang Y, Li C, Shi L, Chen X, Cui C, Huang J, Chen B, Hall DD, Pan Z, Lu M, Hong J, Song LS, Zhao S Tags: Circulation Source Type: research

Can HFpEF and HFrEF Coexist?
PMID: 32119583 [PubMed - in process] (Source: Circulation)
Source: Circulation - March 3, 2020 Category: Cardiology Authors: Schiattarella GG, Tong D, Hill JA Tags: Circulation Source Type: research

Irregular Tachycardia in a Patient With Cardiomyopathy: It Takes Two to Tango.
PMID: 32119584 [PubMed - in process] (Source: Circulation)
Source: Circulation - March 3, 2020 Category: Cardiology Authors: Nabavizadeh P, Rajsheker S, Attari M Tags: Circulation Source Type: research

A Novel Treatment for Vascular Calcification in Patients With Dialysis-Dependent Chronic Kidney Disease: Are We There Yet?
PMID: 32119585 [PubMed - in process] (Source: Circulation)
Source: Circulation - March 3, 2020 Category: Cardiology Authors: Hedayati SS Tags: Circulation Source Type: research

Letter by Tsuda Regarding Article, "Effect of Empagliflozin on Left Ventricular Mass in Patients With Type 2 Diabetes Mellitus and Coronary Artery Disease: The EMPA-HEART CardioLink-6 Randomized Clinical Trial".
Letter by Tsuda Regarding Article, "Effect of Empagliflozin on Left Ventricular Mass in Patients With Type 2 Diabetes Mellitus and Coronary Artery Disease: The EMPA-HEART CardioLink-6 Randomized Clinical Trial". Circulation. 2020 Mar 03;141(9):e100-e101 Authors: Tsuda K PMID: 32119586 [PubMed - in process] (Source: Circulation)
Source: Circulation - March 3, 2020 Category: Cardiology Authors: Tsuda K Tags: Circulation Source Type: research

Highlights From the Circulation Family of Journals.
Authors: PMID: 32119587 [PubMed - in process] (Source: Circulation)
Source: Circulation - March 3, 2020 Category: Cardiology Tags: Circulation Source Type: research

Combined American Heart Association Updated Health Principles/Rural Health Advisory: Reflections on a Journey Through Health Reform.
PMID: 32119588 [PubMed - in process] (Source: Circulation)
Source: Circulation - March 3, 2020 Category: Cardiology Authors: Warner JJ, Churchwell K, Johnson J Tags: Circulation Source Type: research

Midlife Consequences of Cumulative Blood Pressure Exposure: Importance of a Lifespan Approach.
PMID: 32119589 [PubMed - in process] (Source: Circulation)
Source: Circulation - March 3, 2020 Category: Cardiology Authors: Jefferson AL Tags: Circulation Source Type: research

A Comprehensive Evaluation of Rhythm Monitoring Strategies in Screening for Atrial Fibrillation: Insights from Patients at Risk Long-Term Monitored with Implantable Loop Recorder.
Svendsen JH Abstract Background: Stroke is an increasing health problem world-wide. Atrial fibrillation (AF) is a major risk factor for stroke, and the attention towards AF screening is rising, while new monitoring-technologies emerge. We aimed to evaluate the performance of a large panel of screening strategies and to assess population characteristics associated with diagnostic yield. Methods: Persons with stroke risk factors but without AF were recruited from the general population to undergo screening with implantable loop recorder (ILR). New-onset AF lasting ≥6 min was adjudicated by senior cardiologists. A...
Source: Circulation - March 2, 2020 Category: Cardiology Authors: Diederichsen SZ, Haugan KJ, Kronborg C, Graff C, Højberg S, Køber L, Krieger D, Holst AG, Nielsen JB, Brandes A, Svendsen JH Tags: Circulation Source Type: research

Evidence from Family Studies for Autoimmunity in Arrhythmogenic Right Ventricular Cardiomyopathy: Associations of Circulating Anti-Heart and Anti-Intercalated Disk Autoantibodies with Disease Severity and Family History.
Conclusions: Presence of AHA and AIDA provides evidence of autoimmunity in the majority of familial and in almost half of sporadic ARVC. In probands and in AR these antibodies were associated with disease severity features; longitudinal studies are needed to clarify whether they may predict ARVC development in HR or if they be a result of manifest ARVC. PMID: 32114801 [PubMed - as supplied by publisher] (Source: Circulation)
Source: Circulation - March 2, 2020 Category: Cardiology Authors: Caforio ALP, Re F, Avella A, Marcolongo R, Baratta P, Seguso M, Gallo N, Plebani M, Izquierdo-Bajo A, Cheng CY, Syrris P, Elliott PM, d'Amati G, Thiene G, Basso C, Gregori D, Iliceto S, Zachara E Tags: Circulation Source Type: research