SPTLC3 Is Essential for Complex I Activity and Contributes to Ischemic Cardiomyopathy

CONCLUSIONS: Our findings suggest a novel essential role for SPTLC3 in electron transport chain function and a contribution to ischemic injury by regulating complex I activity.PMID:38660786 | DOI:10.1161/CIRCULATIONAHA.123.066879

Source: Circulation - April 25, 2024 Category: Cardiology Authors: Anna Kovilakath Adolfo G Mauro Yolander Valentine Frank Raucci Maryam Jamil Christiane Carter Jeremy Thompson Qun Chen Beutner Gisela Yang Yue Jeremy Allegood Xiaoxin X Wang Jordan Dail Teja Devarakonda Komuraiah Myakala Jolene J Windle Mark A Subler Davi Source Type: research