Zydus Lifesciences gets USFDA nod for generic heart failure treatment drug
Ivabradine is indicated to reduce the risk of hospitalisation for worsening heart failure in adult patients with stable, symptomatic chronic heart failure with certain conditions, the company said. It is also used in children aged six months and older for the treatment of stable symptomatic heart failure due to cardiomyopathy, it added. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - December 1, 2023 Category: Pharmaceuticals Source Type: news
Mayo Clinic study explores heart failure, uncovers gene's role in recovery
Mayo Clinic researchers studying the genetics of people who had recently developed dilated cardiomyopathy, one of the most common causes of heart failure, have found a particular gene to target for developing future drug therapy treatments. The disease makes it harder for the heart's left ventricle to pump blood effectively to the rest of the body. In this first genome-wide association study, the researchers sought to understand why some patients get better after developing the condition —… (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - November 29, 2023 Category: Databases & Libraries Source Type: news
' Smart' Stethoscope Spots Peripartum Cardiomyopathy'Smart' Stethoscope Spots Peripartum Cardiomyopathy
Screening with an AI-enhanced digital stethoscope doubled the diagnoses of life-threatening peripartum cardiomyopathy in Nigeria, where the incidence is the highest in the world.Medscape Medical News (Source: Medscape Pediatrics Headlines)
Source: Medscape Pediatrics Headlines - November 21, 2023 Category: Pediatrics Tags: Cardiology News Source Type: news
Ultra-early phase scintigraphy detects ATTR cardiac amyloidosis
In this study, the researchers analyzed imaging in four patients with ATTR-CA and four patients with hypertensive cardiomyopathy (non-CA) who underwent dynamic scintigraphic scanning. They reconstructed planar images every minute from three to 20 minutes and then every five minutes from 25 to 60 minutes after injection. The H/CL ratio was assessed on each planar image. The H/CL ratio on the planar images acquired at five minutes post-injection showed a significant difference between ATTR-CA and non-CA patients, according to the findings.Ultra-early phase Tc-99m PYP scintigraphy can detect ATTR-CA with 100% sensitivity a...
Source: AuntMinnie.com Headlines - November 15, 2023 Category: Radiology Authors: Will Morton Tags: 2023 Molecular Imaging Preview Source Type: news
Clinical research shows AI-enabled digital stethoscope can detect pregnancy-related heart disease
New research from Mayo Clinic suggests that artificial intelligence (AI) could improve the diagnosis of peripartum cardiomyopathy, a potentially life-threatening and treatable condition that weakens the heart muscle of women during pregnancy or in the months after giving birth. Researchers used an AI-enabled digital stethoscope that captures electrocardiogram (ECG) data and heart sounds to identify twice as many cases of peripartum cardiomyopathy as compared to regular care, according to a news release from the American… (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - November 13, 2023 Category: Databases & Libraries Source Type: news
What to Know About Hypertrophic Cardiomyopathy in Kids
The human heart is a muscle, but it’s also a kind of complicated balloon—a balloon that fills and empties roughly 60 to 100 times every minute, and several billion times during the course of a lifetime.
Among people with hypertrophic cardiomyopathy, the walls of the heart muscle are abnormally thick. This thickness can interfere with the heart’s normal filling-and-emptying operation. “If you think of a balloon made with super-thick rubber, you have to blow harder to fill it, and it’s the same with a hypertrophic heart,” says Dr. Daphne Hsu, professor of pediatrics and medicine at Ped...
Source: TIME: Health - November 2, 2023 Category: Consumer Health News Authors: Markham Heid Tags: Uncategorized freelance healthscienceclimate Source Type: news
A Dozen Genes Found Dangerous in Pregnancy A Dozen Genes Found Dangerous in Pregnancy
Conditions linked to the 12 genes included cardiomyopathy, hemorrhage, gestational hypertensive disorders and more.MDedge News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - October 25, 2023 Category: Consumer Health News Tags: Ob/Gyn & Women ' s Health News Source Type: news
'I've lived for a year without a PULSE... I run on batteries': Massachusetts woman, 30, with rare genetic condition is being kept alive by mechanical implant as she waits anxiously for a donor to give her a new heart
Sofia Hart, 30, from Massachusetts, has irreversible dilated cardiomyopathy - when one of the ventricles does not work as well, which can lead to heart failure. (Source: the Mail online | Health)
Source: the Mail online | Health - October 25, 2023 Category: Consumer Health News Source Type: news
'I've lived for a year without a PULSE... I run on batteries' Massachusetts woman, 30, with rare genetic condition is being kept alive by mechanical implant as she waits anxiously for a donor to give her a new heart
Sofia Hart, 30, from Massachusetts, has irreversible dilated cardiomyopathy - when one of the ventricles does not work as well, which can lead to heart failure. (Source: the Mail online | Health)
Source: the Mail online | Health - October 24, 2023 Category: Consumer Health News Source Type: news
FDA Denies Approval for Patisiran in ATTR Cardiomyopathy FDA Denies Approval for Patisiran in ATTR Cardiomyopathy
In a complete response letter, the FDA said the clinical meaningfulness of patisiran ' s effects in cardiomyopathy of ATTR amyloidosis are not established, despite good reviews from an advisory panel.Medscape Medical News (Source: Medscape Internal Medicine Headlines)
Source: Medscape Internal Medicine Headlines - October 10, 2023 Category: Internal Medicine Tags: Cardiology News Alert Source Type: news
Episode 11: Peripartum Cardiomyopathy and Pregnancy in Heart Failure Episode 11: Peripartum Cardiomyopathy and Pregnancy in Heart Failure
Drs Michelle M. Kittleson and Kathryn J. Lindley discuss current approaches to treating patients with peripartum cardiomyopathy as well as patients with heart failure who want to become pregnant.Medscape (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 10, 2023 Category: Consumer Health News Tags: Cardiology InDiscussion Source Type: news
FDA Turns Down ATTR Cardiomyopathy Drug
(MedPage Today) -- CLEVELAND -- In a surprise Monday morning move, the FDA declined to expand the indication for anti-amyloid agent patisiran (Onpattro) in treating wild-type or hereditary transthyretin amyloid cardiomyopathy (ATTR-CM, or cardiac... (Source: MedPage Today Public Health)
Source: MedPage Today Public Health - October 9, 2023 Category: American Health Source Type: news
Base Pair Bio Receives Grant from NIH to Help Deliver Therapies for Genetic Heart Disease
Base Pair Biotechnologies, "The Aptamer Discovery Company™" has been recently awarded a grant from NIH entitled, "Aptamer engineering of lentiviral vectors for cardiac gene therapies". HOUSTON, Sept. 27, 2023 /PRNewswire-PRWeb/ -- Hypertrophic cardiomyopathy (HCM) is the leading cause of... (Source: PRWeb: Medical Pharmaceuticals)
Source: PRWeb: Medical Pharmaceuticals - September 28, 2023 Category: Pharmaceuticals Source Type: news
Patisiran for ATTR Cardiomyopathy Gets FDA Panel Thumbs Up Patisiran for ATTR Cardiomyopathy Gets FDA Panel Thumbs Up
An FDA advisory committee voted 9 to 3 that the benefits of patisiran outweigh the risks for ATTR cardiomyopathy, but many questioned whether the benefit is clinically meaningful.Medscape Medical News (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - September 14, 2023 Category: Cardiology Tags: Cardiology News Source Type: news
FDA Panel Reluctantly Backs Patisiran for ATTR Cardiomyopathy
(MedPage Today) -- FDA advisors conceded on Wednesday that the benefit-risk balance of patisiran (Onpattro) technically checks out in wild-type or hereditary transthyretin amyloid cardiomyopathy (ATTR-CM, also known as cardiac ATTR amyloidosis... (Source: MedPage Today Nephrology)
Source: MedPage Today Nephrology - September 14, 2023 Category: Urology & Nephrology Source Type: news
