Breakthrough as scientists can now spot leading cause of cardiac arrest in young people
Oxford University scientists have found a way to use MRI scanners to picture the arrangement of muscle fibres in the heart to pick out warning signs of hypertrophic cardiomyopathy. (Source: the Mail online | Health)
Source: the Mail online | Health - May 20, 2019 Category: Consumer Health News Source Type: news

Mother's heartbreak as one of her poorly twins received a new heart while the other is waiting
Mila Costa's identical two year olds, Benjamin and Enzo, have a heart defect, dilated cardiomyopathy. Doctors in Brazil gave Enzo a new heart and he has since bounced back. (Source: the Mail online | Health)
Source: the Mail online | Health - May 15, 2019 Category: Consumer Health News Source Type: news

Tafamidis for Transthyretin Amyloid Cardiomyopathy Tafamidis for Transthyretin Amyloid Cardiomyopathy
A new drug for the treatment of transthyretin cardiomyopathy looks to be a game-changer; but will it benefit all TTR patients?European Heart Journal (Source: Medscape Radiology Headlines)
Source: Medscape Radiology Headlines - May 13, 2019 Category: Radiology Tags: Cardiology Journal Article Source Type: news

The ECG and the Phenotypic Expression of HCM The ECG and the Phenotypic Expression of HCM
What is the significance of marked ECG abnormalities in an individual with a positive genotype for hypertrophic cardiomyopathy?European Heart Journal (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 8, 2019 Category: Consumer Health News Tags: Cardiology Journal Article Source Type: news

Continuous ECG Changes Over 8 Years in an Athlete With HCM Continuous ECG Changes Over 8 Years in an Athlete With HCM
This case report reveals that abnormal ECG findings may precede the symptoms and signs of hypertrophic cardiomyopathy for many years.Journal of Medical Case Reports (Source: Medscape Radiology Headlines)
Source: Medscape Radiology Headlines - May 8, 2019 Category: Radiology Tags: Cardiology Journal Article Source Type: news

FDA Approves New Treatments Vyndaqel (tafamidis meglumine) and Vyndamax (tafamidis) for Heart Disease Caused by Transthyretin Mediated Amyloidosis
May 06, 2019 -- On May 3, the U.S. Food and Drug Administration approved Vyndaqel (tafamidis meglumine) and Vyndamax (tafamidis) capsules for the treatment of the heart disease (cardiomyopathy) caused by transthyretin mediated amyloidosis (ATTR-CM)... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - May 6, 2019 Category: Drugs & Pharmacology Source Type: news

FDA Approves Treatments for Heart Failure Caused by Rare Disease
MONDAY, May 6, 2019 -- Vyndaqel (tafamidis meglumine) and Vyndamax (tafamidis) capsules have been approved to treat adults with cardiomyopathy caused by transthyretin mediated amyloidosis (ATTR-CM), the U.S. Food and Drug Administration announced... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - May 6, 2019 Category: Pharmaceuticals Source Type: news

Two Drugs Approved for Cardiomyopathy Caused by Amyloidosis
Two different versions of tafamadis get the FDA ’s nod to treat a rare heart disease.  (Source: ConsultantLive)
Source: ConsultantLive - May 6, 2019 Category: Internal Medicine Authors: Valerie DeBenedette Tags: Cardiology Cardiovascular Diseases Heart Health Latest e-News New Products The Latest Source Type: news

FDA OKs Two Tafamidis Formulations for Rare Cardiomyopathy FDA OKs Two Tafamidis Formulations for Rare Cardiomyopathy
These are the first FDA-approved treatments for transthyretin-mediated amyloidosis cardiomyopathy, a rare and often fatal disease caused by deposition of amyloid fibrils in the myocardium.FDA Approvals (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - May 6, 2019 Category: Cardiology Tags: Cardiology News Alert Source Type: news

Pfizer gets U.S. approval for $225,000 a year heart drug
The U.S. Food and Drug Administration on Monday approved Pfizer Inc's oral drug, tafamidis, to treat a rare and fatal heart disease called transthyretin amyloid cardiomyopathy, the U.S drugmaker said. (Source: Reuters: Health)
Source: Reuters: Health - May 6, 2019 Category: Consumer Health News Tags: healthNews Source Type: news

FDA approves new treatments for heart disease caused by a serious rare disease, transthyretin mediated amyloidosis
On May 3, the U.S. Food and Drug Administration approved Vyndaqel (tafamidis meglumine) and Vyndamax (tafamidis) capsules for the treatment of the heart disease (cardiomyopathy) caused by transthyretin mediated amyloidosis (ATTR-CM) in adults. These are the first FDA-approved treatments for ATTR-CM. Vyndaqel and Vyndamax have the same active moiety, tafamidis, but they are not substitutable on a milligram to milligram basis and their recommended doses differ. (Source: World Pharma News)
Source: World Pharma News - May 6, 2019 Category: Pharmaceuticals Tags: Featured FDA Regulatory Affairs Source Type: news

Takotsubo Cardiomyopathy After an Upper and Lower Endoscopy Takotsubo Cardiomyopathy After an Upper and Lower Endoscopy
This case presents management approaches which can be used when treating at-risk patients who have experienced symptoms of stress cardiomyopathy after undergoing endoscopy.Journal of Medical Case Reports (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 1, 2019 Category: Consumer Health News Tags: Cardiology Journal Article Source Type: news

A promising new treatment for infants with Noonan syndrome
(University of Montreal) Infants less than six months old with Noonan Syndrome, hypertrophic cardiomyopathy and congestive heart failure normally have a poor prognosis, with a one-year survival rate of 34%. In the new study, doctors used Trametinib to try to treat NS in two patients.They observed dramatic improvement of clinical and cardiac status in the patients only three months after treatment. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 30, 2019 Category: International Medicine & Public Health Source Type: news

Apr 19 2019 This Week in Cardiology Apr 19 2019 This Week in Cardiology
Anticoagulation for embolic stroke of unknown origin, added-sugar labels, AF-patient knowledge, LDL-C and hemorrhagic stroke, and genetic signals in cancer-care cardiomyopathy are discussed this week.theheart.org on Medscape (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - April 19, 2019 Category: Cardiology Tags: Cardiology Commentary Source Type: news

Genetic Crosstalk in Cancer Therapy-Induced Cardiomyopathy Genetic Crosstalk in Cancer Therapy-Induced Cardiomyopathy
A genetic study links cancer-therapy-induced and dilated cardiomyopathies and signals how identification of genetic risk factors may help change management of those at risk.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - April 18, 2019 Category: Consumer Health News Tags: Cardiology News Source Type: news

Genetic Crosstalk in Cancer-Therapy-Induced Cardiomyopathy Genetic Crosstalk in Cancer-Therapy-Induced Cardiomyopathy
A genetic study links cancer-therapy-induced and dilated cardiomyopathies and signals how identification of genetic risk factors may help change management of those at risk.Medscape Medical News (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - April 18, 2019 Category: Cardiology Tags: Cardiology News Source Type: news

Chagas Cardiomyopathy: The Disease You Might Not Think Of Chagas Cardiomyopathy: The Disease You Might Not Think Of
A growing public health threat demands more awareness of Chagas disease and its manifestations.Medscape Infectious Diseases (Source: Medscape Infectious Diseases Headlines)
Source: Medscape Infectious Diseases Headlines - April 16, 2019 Category: Infectious Diseases Tags: Infectious Diseases Case Challenge Source Type: news

A new role for genetics in cancer therapy-induced cardiomyopathy
(Brigham and Women's Hospital) A team of investigators from Brigham and Women's Hospital and Harvard Medical School finds that genetics may be at play and elucidates rare genetic variants which may influence risk for developing cancer therapy-induced cardiomyopathy. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 10, 2019 Category: International Medicine & Public Health Source Type: news

Computer Model Predicts Risk for Ventricular Arrythmia in ARVC
WEDNESDAY, April 3, 2019 -- A new model can predict the risk for incident ventricular arrhythmias (VAs) in patients with arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVC), according to a study published online March 27 in the European... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - April 3, 2019 Category: Pharmaceuticals Source Type: news

Atrial Arrhythmias in Takotsubo Syndrome Atrial Arrhythmias in Takotsubo Syndrome
Inflammation may be a predictor for new onset atrial arrhythmias in Takotsubo cardiomyopathy.Europace (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 22, 2019 Category: Consumer Health News Tags: Cardiology Journal Article Source Type: news

ACC 2019: Medtronic, Edwards low-risk TAVR trial data could pave way to new indications
Results from trials of both Medtronic‘s (NYSE:MDT) and Edwards Lifesciences‘ (NYSE:EW) transcatheter aortic valve replacement systems exploring their use in low-risk patients indicated that the devices were as safe as open surgery, paving the way for possible new indications for TAVR technology. Data from the trials were presented over the weekend at the American College of Cardiology 68th Annual Scientific Session 2019 in New Orleans and simultaneously published in the New England Journal of Medicine. Currently, TAVR devices are only approved by the FDA for treating severe aortic valve stenosis in patients at ...
Source: Mass Device - March 18, 2019 Category: Medical Devices Authors: Fink Densford Tags: Cardiac Implants Cardiovascular Clinical Trials Featured Replacement Heart Valves Edwards Lifesciences Medtronic Source Type: news

Novartis joins the Global Chagas Disease Coalition and also announces first multinational, prospective, randomized study in people with chronic Chagas cardiomyopathy
At the Annual Meeting of the Global Chagas Disease Coalition in Barcelona, Spain, Novartis announced that it is joining the Coalition as a member contributor. In addition, the company announced its commitment to launch a multinational, prospective, randomized study with heart failure drug, Entresto® (sacubitril / valsartan), in people with chronic Chagas cardiomyopathy, one form of heart failure with reduced ejection fraction. (Source: World Pharma News)
Source: World Pharma News - March 15, 2019 Category: Pharmaceuticals Tags: Featured Novartis Business and Industry Source Type: news

Long - Term Cardiomyopathy Risk Varies by Chemo Agent
Decreased risk seen for daunorubicin versus doxorubicin among survivors of childhood cancer (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - March 1, 2019 Category: Cancer & Oncology Tags: Cardiology, Oncology, Pediatrics, Pharmacy, Journal, Source Type: news

Long-Term Cardiomyopathy Risk Varies by Chemo Agent
FRIDAY, March 1, 2019 -- Long-term cardiomyopathy risk varies by chemotherapy agent for childhood cancer survivors, with a decreased risk for daunorubicin versus doxorubicin, according to a study recently published in JAMA Oncology. Elizabeth A.M.... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - March 1, 2019 Category: Pharmaceuticals Source Type: news

What Is the Most Common Type of Cardiomyopathy?
Discussion Barth syndrome is characterized by a dilated cardiomyopathy, proximal skeletal muscle weakness, neutropenia and short stature that usually presents at birth or soon after. It is a rare X-linked recessive disease process caused by mutations in the TAZ gene. The TAZ gene codes for tafazzin which alters cardiolipin in mitochondria. Characteristic facies can be seen especially in infancy including a tall and broad forehead, prominent chin and full cheeks, larger ears, and deep-set eyes. Most patients present at birth or soon afterwards but some may not until later in life. Life expectancy is reduced with many childr...
Source: PediatricEducation.org - February 25, 2019 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Astaxanthin found to protect the heart in diabetics, researchers confirm
(Natural News) Most diabetes-related mortality incidences can be attributed to its complications. One of the most serious consequences caused by this disease is a heart condition called diabetic cardiomyopathy. Left untreated, diabetic cardiomyopathy can progress into congestive heart failure, which poses a severe threat to the patient’s life. Fortunately, researchers from The First Affiliated Hospital Of Nanjing Medical University and The... (Source: NaturalNews.com)
Source: NaturalNews.com - February 24, 2019 Category: Consumer Health News Source Type: news

Scientists unravel genetic basis of hypertrophic cardiomyopathy in Finns
(University of Eastern Finland) One third of hypertrophic cardiomyopathy cases in Finland are caused by one of the four major mutations, a new study from the University of Eastern Finland and Kuopio University Hospital shows. Overall, 40 percent of patients carried a specific or a likely mutation causing the disease, and 20 percent were carriers of a rare gene mutation whose role in the disease remains unknown. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 22, 2019 Category: International Medicine & Public Health Source Type: news

Yale New Haven becomes first in CT to perform pediatric heart transplants
Families from Connecticut and Rhode Island will now have close access to pediatric care for congenital heart defects, cardiomyopathy, and other conditions. (Source: Yale Science and Health News)
Source: Yale Science and Health News - February 19, 2019 Category: Universities & Medical Training Source Type: news

Astaxanthin reduces myocardial damage in diabetics, researchers find
(Natural News) A multi-university study from China has found that astaxanthin has protective effects against diabetic cardiomyopathy. This finding, which was published in CyTA – Journal of Food, was based on the results of in vivo studies conducted on rats. Diabetes mellitus is associated with complications that affect a wide range of body tissues, including the heart.... (Source: NaturalNews.com)
Source: NaturalNews.com - February 14, 2019 Category: Consumer Health News Source Type: news

New research insights hold promise for kids with DMD
(Children's National Health System) Prednisone, the current standard of care used to treat kids with Duchenne muscular dystrophy (DMD), reduces chronic inflammation but has harsh side effects. Eplerenone, a heart failure drug, is used in older patients to treat cardiomyopathy, a leading cause of mortality for people with DMD. A new medicine under development appears to combine the beneficial effects of these drugs for the heart and muscle while also showing improved safety in experimental models. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 11, 2019 Category: International Medicine & Public Health Source Type: news

Trimetazidine Disappoints in Non-Obstructive Cardiomyopathy
(MedPage Today) -- Anti-anginal agent is the latest drug to flop as an effective therapy remains elusive (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - February 6, 2019 Category: Cardiology Source Type: news

Do all chemotherapies have equal long-term heart risk?
(University of Texas Health Science Center at San Antonio) Different chemotherapy drugs were associated with varying degrees of long-term risk of cardiomyopathy in survivors of childhood cancers, according to a new study that included a researcher from UT Health San Antonio. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - January 31, 2019 Category: Cancer & Oncology Source Type: news

Bad brakes
(Harvard Medical School) A study in human and mouse heart cells identifies a faulty molecular brake in the most common form of hypertrophic cardiomyopathy, a leading cause of sudden cardiac death in young people and athletes and the most common genetic disease of the heart The faulty brake, found about a quarter of all genetic mutations in hypertrophic cardiomyopathy, interferes with the heart muscle's ability to contract and relax,.Treatment with a chemical compound successfully restores normal contractility and relaxation in human heart cells (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 28, 2019 Category: International Medicine & Public Health Source Type: news

US FDA accepts regulatory submissions for review of tafamidis to treat transthyretin amyloid cardiomyopathy
Pfizer Inc. (NYSE: PFE) announced today that the US Food and Drug Administration (FDA) accepted for filing the company's New Drug Applications (NDAs) for tafamidis for the treatment of transthyretin amyloid cardiomyopathy (ATTR-CM). Pfizer has submitted two NDAs based on two forms of tafamidis: meglumine salt and free acid. (Source: World Pharma News)
Source: World Pharma News - January 14, 2019 Category: Pharmaceuticals Tags: Featured Pfizer Business and Industry Source Type: news

US FDA Accepts Regulatory Submissions for Review of Tafamidis to Treat Transthyretin Amyloid Cardiomyopathy
January 14, 2019 - Pfizer Inc. (NYSE: PFE) announced today that the US Food and Drug Administration (FDA) accepted for filing the company’s New Drug Applications (NDAs) for tafamidis for the treatment of transthyretin amyloid cardiomyopathy... (Source: Drugs.com - New Drug Applications)
Source: Drugs.com - New Drug Applications - January 14, 2019 Category: Drugs & Pharmacology Source Type: news

What Are Potential Complications of Large for Gestational Birthweight?
Discussion Infant size at birth is determined mainly by genetics, but also pregnancy and environmental factors. Large for gestational age (LGA) is defined as a mean weight> 2 standard deviations above the weight for gestational age or above the 90th percentile on growth charts (or ~4000 g on WHO growth charts). Macrosomia is a term used for a term infant who is> 4000g. Risk factors for LGA infants includes: Male infant Maternal Genetic disposition Hispanic ethnicity Diabetic Multiparity or grand parity Obesity History of previous LGA infant Prenatal ultrasound is very helpful for antenatal management. First tri...
Source: PediatricEducation.org - January 14, 2019 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Researchers discover a hidden culprit in heart failure
(University of Alberta Faculty of Medicine& Dentistry) An international research team led by scientists at the University of Alberta have pinpointed a hidden culprit that leads to dilated cardiomyopathy--a dangerous condition that accounts for 20 per cent of all cases of heart failure--which opens the door to potential new treatments that could help counter the threat. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 10, 2019 Category: International Medicine & Public Health Source Type: news

Student has heart transplant after her tiredness became deadly
Charlotte Carney, from Northwich in Cheshire, was diagnosed with restrictive cardiomyopathy last year after spending years suffering from fatigue and sleeping for up to 20 hours a day. (Source: the Mail online | Health)
Source: the Mail online | Health - January 2, 2019 Category: Consumer Health News Source Type: news

Hypertrophic Cardiomyopathy: A to Z with Richard Bach, MD
(MedPage Today) -- Andrew Perry, MD, interviews specialty center director (Source: MedPage Today Nephrology)
Source: MedPage Today Nephrology - December 28, 2018 Category: Urology & Nephrology Source Type: news

Heart Transplant Recipient Helping Beverly Family Who Lost Their Son
BOSTON (CBS) – In April 2018, a Beverly couple tragically lost their son. As Jonathan Ersing’s parents grieve, they have found a unique way to remain close to him. “He was just one of those people who just lit up a room,” his mother, Joanne, remembers. Jonathan had severe autism and in April, he accidentally choked on his food and went into cardiac arrest. After multiple attempts to resuscitate him, Jonathan was pronounced brain dead. He was 25 years old. Jonathan Ersing (Courtesy Photo) While Jonathan was losing his life, Sabrina Dahoda of upstate New York was on the brink of losing hers. The 31-ye...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - December 26, 2018 Category: Consumer Health News Authors: Health – CBS Boston Tags: Boston News Health Seen On WBZ-TV Syndicated Local Brigham And Woman's Hospital Dr. Mallika Marshall Heart Transplant Organ Donation Source Type: news

Genetic Basis of Early-Onset AF: The Case Titins Genetic Basis of Early-Onset AF: The Case Titins
The presence of loss-of-function variants in a gene encoded for the sarcomeric protein titin was elevated in people with early-onset atrial fibrillation and no cardiomyopathy.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - December 18, 2018 Category: Consumer Health News Tags: Cardiology News Source Type: news

George H.W. Bush Died Less Than 8 Months After His Wife of 73 Years. Doctors Explain Why That ’s So Common
George H.W. Bush died in his Houston home on Nov. 30, less than eight months after his wife of 73 years, Barbara. He was 94. While Bush’s case may seem extraordinary, it’s actually fairly common for spouses to die around the same time. A 2013 study published in the Journals of Gerontology found that the death of a spouse raises a person’s risk of dying by around 30%, compared to those who are still married. Some estimates are even higher. Some research has shown that in the six months after the death of a spouse, the bereaved face odds of mortality 40% to 70% greater than the general public, according to ...
Source: TIME: Health - December 1, 2018 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized healthytime medicine onetime Source Type: news

Britons are clueless about their bodies: Millions have no idea what they weigh
Chris Marshall, 44, from West Sussex, who would play sport 'at any opportunity' collapsed suddenly due to cardiomyopathy. The doctor cycled more than 20 miles a day to work. (Source: the Mail online | Health)
Source: the Mail online | Health - November 27, 2018 Category: Consumer Health News Source Type: news

Myocardial injury after carbon monoxide intoxication in suicide attempt, with features of both toxic and tako-tsubo cardiomyopathy: case report - Van čata R, Lhotský J, Beránek V, Krištof J, Rokyta R.
Severe carbon monoxide intoxication may cause tissue injury by hypoxemia and histotoxicity. The affection of the heart muscle often leads to transient global or regional systolic dysfunction of left ventricle or both ventricles and increased occurences of ... (Source: SafetyLit)
Source: SafetyLit - November 21, 2018 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

The woman who nearly died of a broken heart at 26
Helen Ross, now 38, from Canterbury in Kent, was diagnosed with stress-induced cardiomyopathy – known as broken heart syndrome – when she broke up with her childhood sweetheart. (Source: the Mail online | Health)
Source: the Mail online | Health - November 20, 2018 Category: Consumer Health News Source Type: news

The actress who almost died from undetected heart condition
Rebecca Shorrocks nearly lost her life to cardiomyopathy - a heart condition she never knew she had. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - November 18, 2018 Category: Consumer Health News Source Type: news

Tako-Tsubo Cardiomyopathy in Severe Sepsis: Nationwide Trends, Predictors, and Outcomes
The authors of this research article state that there are limited data on the presentation of Takotsubo cardiomyopathy ( TTC ) in severe sepsis. Methods and Results This was a retrospective cohort study using the National Inpatient Sample database (2007-2013) of all adults with severe sepsis. TTC was identified in patients with severe sepsis using previously validated administrative codes. TTC is observed with increasing frequency in severe sepsis and was associated with a significantly lower in-hospital mortality compared with patients without TTC . Presentation in later years of the study period, middle age, female sex, ...
Source: Current Awareness Service for Health (CASH) - November 16, 2018 Category: Consumer Health News Source Type: news

Heart Failure Patients Shouldn't Stop Meds Even if Condition Improves: Study
TUESDAY, Nov. 13, 2018 -- There's bad news for heart failure patients with dilated cardiomyopathy who'd like to stop taking their meds. Any progress they've seen on medication is likely to fade once they stop taking their heart drugs, new clinical... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - November 13, 2018 Category: General Medicine Source Type: news

Glad Your EF Is Better, But Stay on Your Meds Glad Your EF Is Better, But Stay on Your Meds
While the TRED-HF trial may not be great news for patients with dilated cardiomyopathy and recovered EF, at least it eases this physician's conscience about her reluctance to curtail pharmacotherapy.Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 12, 2018 Category: Consumer Health News Tags: Cardiology Expert Column Source Type: news