Myocardial fibrosis in pathogenesis, diagnosis & treatment of hypertrophic cardiomyopathy
(Compuscript Ltd) In a new publication from Cardiovascular Innovations and Applications; DOI https://doi.org/10.15212/CVIA.2021.0008, Zeyi Cheng, Miaomiao Qi, Chengyuan Zhang and Yanxia Mao from Sichuan University, Sichuan, China, Second Hospital of Lanzhou University, Lanzhou, China and The Second Medical School of Lanzhou University, Lanzhou, China consider myocardial fibrosis in the pathogenesis, diagnosis, and treatment of hypertrophic cardiomyopathy. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 27, 2021 Category: International Medicine & Public Health Source Type: news

Tafamidis Should Be Accessible for All Patients With ATTR-CM Tafamidis Should Be Accessible for All Patients With ATTR-CM
Tafamidis, a daily, orally available medication, has proven highly effective in the treatment of transthyretin amyloid cardiomyopathy, but its high cost puts it out of reach of most patients.JACC: Heart Failure (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 26, 2021 Category: Consumer Health News Tags: Cardiology Journal Article Source Type: news

ECG Challenge: Hypotension in a Cardiomyopathy Patient ECG Challenge: Hypotension in a Cardiomyopathy Patient
A 69-year-old woman presents with shortness of breath and hypotension, with tests revealing pulmonary edema and acute renal insufficiency. What does the ECG show?Medscape Cardiology (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - March 23, 2021 Category: Cardiology Tags: Cardiology Clinical Case Source Type: news

U.S. Food and Drug Administration (FDA) Accepts Bristol Myers Squibb ’s Application for Mavacamten in Symptomatic Obstructive Hypertrophic Cardiomyopathy (oHCM)
PRINCETON, N.J.--(BUSINESS WIRE)-- March 19, 2021 -- Bristol Myers Squibb (NYSE: BMY) today announced that the U.S. Food and Drug Administration (FDA) has accepted its New Drug Application (NDA) for mavacamten, an investigational, novel, oral,... (Source: Drugs.com - New Drug Applications)
Source: Drugs.com - New Drug Applications - March 19, 2021 Category: Drugs & Pharmacology Source Type: news

The poisoned heart: a case of Takotsubo cardiomyopathy induced by carbon monoxide poisoning - Lakhani M, Alkhero M, Bains N, Steele R, Abdelmalik R.
BACKGROUND: Carbon monoxide is a common environmental toxin, and some patients present with features of cardiac injury in addition to the noxious effects of carbon monoxide poisoning. A very small fraction of those have a transient left ventricular apical ... (Source: SafetyLit)
Source: SafetyLit - March 12, 2021 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

Exploring pieces of heart muscle that fail to compact
(University of Houston) Of those diagnosed with a " spongy heart, " 47% will die. University of Houston pharmacologist Mingfu Wu has been awarded $2.5 million from the National Heart, Lung, and Blood Institute to explore the cause of and therapeutic treatment for the heart disease officially called left ventricular non-compaction cardiomyopathy (LVNC). (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 4, 2021 Category: International Medicine & Public Health Source Type: news

FSU College of Medicine researcher develops new possibilities to prevent sudden cardiac death
(Florida State University) Stephen Chelko, an assistant professor of biomedical sciences at the Florida State University College of Medicine, has developed a better understanding of the pathological characteristics behind arrhythmogenic cardiomyopathy, as well as promising avenues for prevention. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 17, 2021 Category: International Medicine & Public Health Source Type: news

Mayo Clinic Q and A: Hypertrophic cardiomyopathy
DEAR MAYO CLINIC: My sister was just told she has hypertrophic cardiomyopathy. I've heard of that causing sudden death in athletes. She says she feels fine and doesn't need treatment now, so is she at low risk? What does her diagnosis mean for me and my family? ANSWER: Hypertrophic cardiomyopathy is a fairly common heart condition, affecting [...] (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - February 3, 2021 Category: Databases & Libraries Source Type: news

Heart defect that kills thousands without warning could be spotted early by a blood test 
Hypertrophic cardiomyopathy, which causes the heart muscle to abnormally thicken and beat out of control, is the leading cause of cardiac arrest and sudden death in under-40s. (Source: the Mail online | Health)
Source: the Mail online | Health - January 31, 2021 Category: Consumer Health News Source Type: news

AHA/ACC Urge Shared Decisions in Hypertrophic Cardiomyopathy
MONDAY, Dec. 21, 2020 -- Updated clinical practice guidelines from the American Heart Association/American College of Cardiology, published online Nov. 20 in Circulation, emphasize shared decision-making in the management of hypertrophic... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - December 21, 2020 Category: Pharmaceuticals Source Type: news

Joelle's journey to a new heart
Cardiomyopathy is a medical term for a number of genetic and nongenetic diseases involving the heart muscle that adversely affect the heart's mechanical pumping function and its electrical system. It can occur in people of all ages, races or genders, and it is a frequent cause of sudden cardiac arrest and sudden cardiac death. For [...] (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - December 8, 2020 Category: Databases & Libraries Source Type: news

What Areas of the Physical Examination are Important in the Pre-participation Physical Examination?
Discussion Participation in organized or non-organized, recreational to elite sports activities can provide excellent recreational and leisure time activities and improve physical and mental health for participants. The Aspen Institute in 2018 reported that more kids are being physically active, more are trying different sports, and multisports play is increasing rather than strict specialization. Unfortunately they note that there is an economic inequality with children from lower-socioeconomic circumstances playing less organized sports. About 70% of children and youth participate in an individual or team sport, but unfo...
Source: PediatricEducation.org - December 7, 2020 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

New HCM Guidelines Make Shared Decision-making Top Priority New HCM Guidelines Make Shared Decision-making Top Priority
An updated guideline for patients with hypertrophic cardiomyopathy (HCM)'puts the patient front and center in the shared decision-making process,'according to a member of the writing committee.Medscape Medical News (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - November 20, 2020 Category: Cardiology Tags: Cardiology News Source Type: news

Hypertrophic cardiomyopathy guideline encourages shared decision-making
(American College of Cardiology) The American Heart Association and the American College of Cardiology today released an updated guideline for managing patients with hypertrophic cardiomyopathy (HCM). The guideline encourages shared decision-making between the clinician and patient as essential when determining treatment course and updates recommendations for sudden cardiac death (SCD) risk assessment and HCM center referrals based on the latest evidence. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 20, 2020 Category: International Medicine & Public Health Source Type: news

Importance of mitochondrial-related genes in dilated cardiomyopathy
(Compuscript Ltd) Importance of Mitochondrial-Related Genes in Dilated Cardiomyopathy Based on Bioinformatics Analysis. In a new publication from Cardiovascular Innovations and Applications; DOI https://doi.org/10.15212/CVIA.2019.0588, Yukuan Chen, Xiaohui Wu, Danchun Hu and Wei Wang, from the Shantou University Medical College, Shantou, China and Second Affiliated Hospital of Shantou University Medical College, Shantou, China consider the importance of mitochondrial-related genes in dilated cardiomyopathy. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 19, 2020 Category: International Medicine & Public Health Source Type: news

Cellular pathway of genetic heart disease similar to neurodegenerative disease
(Mayo Clinic) Research on a genetic heart disease has uncovered a new and unexpected mechanism for heart failure. This landmark discovery found a correlation between the clumping of RNA-binding proteins long linked to neurodegenerative disease and the aggregates of protein found in the heart tissue of patients with RBM20 dilated cardiomyopathy. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 18, 2020 Category: International Medicine & Public Health Source Type: news

A change of heart -- new drug for HCM reduces heart mass
(Michigan Medicine - University of Michigan) For the first time, a medication has impacted heart muscle thickness and function for patients with the most common inherited heart condition, hypertrophic cardiomyopathy, rather than simply addressing their symptoms. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 16, 2020 Category: International Medicine & Public Health Source Type: news

Cellular pathway of genetic heart disease similar to neurodegenerative disease
ROCHESTER, Minn. -- Research on a genetic heart disease has uncovered a new and unexpected mechanism for heart failure. This landmark discovery found a correlation between the clumping of RNA-binding proteins ? long linked to neurodegenerative disease ? and the aggregates of protein found in the heart tissue of patients with RBM20 dilated cardiomyopathy. Dilated [...] (Source: Mayo Clinic Minnesota News)
Source: Mayo Clinic Minnesota News - November 13, 2020 Category: Hospital Management Source Type: news

AHA: Mavacamten May Treat Hypertrophic Cardiomyopathy
THURSDAY, Nov. 12, 2020 -- Compared with placebo, mavacamten (Mava), a novel inhibitor of cardiac myosin, for 30 weeks leads to improvement in left ventricular (LV) hypertrophy and markers of left-sided filling pressures in patients with obstructive... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - November 12, 2020 Category: Pharmaceuticals Source Type: news

New Hope for a Rare Heart Condition
THURSDAY, Nov. 12, 2020 -- An experimental drug might improve heart function for people with a condition called obstructive hypertrophic cardiomyopathy, a new study finds. Hypertrophic cardiomyopathy is a thickening of heart muscle that can... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - November 12, 2020 Category: General Medicine Source Type: news

Penn State's Journey Brown retiring from football due to heart condition
Penn State running back Journey Brown will retire from football after being diagnosed with a heart ailment known as hypertrophic cardiomyopathy. (Source: Reuters: Health)
Source: Reuters: Health - November 12, 2020 Category: Consumer Health News Source Type: news

At What Age Does Hypertrophic Cardiomyopathy Develop?
Title: At What Age Does Hypertrophic Cardiomyopathy Develop?Category: Diseases and ConditionsCreated: 11/9/2020 12:00:00 AMLast Editorial Review: 11/9/2020 12:00:00 AM (Source: MedicineNet Heart General)
Source: MedicineNet Heart General - November 9, 2020 Category: Cardiology Source Type: news

Study reinforces drug's potential to treat hypertrophic cardiomyopathy
(Washington State University) WSU research sheds new light on a molecule that may be used to treat heart conditions that can lead to stroke, heart attack and other forms of heart disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 27, 2020 Category: International Medicine & Public Health Source Type: news

Oct 23 2020 This Week in Cardiology Oct 23 2020 This Week in Cardiology
COVID, tocilizumab, hypertrophic cardiomyopathy, cerebral microbleeds, and surrogate endpoints are the topics discussed by John Mandrola, MD, in this week ’ s podcasttheheart.org on Medscape (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 23, 2020 Category: Consumer Health News Tags: Cardiology Commentary Source Type: news

What Causes Hypertrophic Cardiomyopathy?
Title: What Causes Hypertrophic Cardiomyopathy?Category: Diseases and ConditionsCreated: 10/21/2020 12:00:00 AMLast Editorial Review: 10/21/2020 12:00:00 AM (Source: MedicineNet Heart General)
Source: MedicineNet Heart General - October 21, 2020 Category: Cardiology Source Type: news

Surgery Still Best Option in Obstructive HCM Surgery Still Best Option in Obstructive HCM
Promising results for a novel drug should not push surgical options aside for patients with obstructive hypertrophic cardiomyopathy, argue two surgeons.theheart.org on Medscape (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - October 15, 2020 Category: Cardiology Tags: Cardiology Commentary Source Type: news

Cell Therapy for Anthracycline Cardiomyopathy Safe, Feasible Cell Therapy for Anthracycline Cardiomyopathy Safe, Feasible
In a small phase 1 study, administration of allogeneic bone marrow-derived mesenchymal stromal cells was safe and feasible in patients with anthracycline-induced cardiomyopathy heart failure.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - October 2, 2020 Category: Consumer Health News Tags: Cardiology News Source Type: news

Cardiovascular adverse events associated with hydroxychloroquine and chloroquine: A comprehensive pharmacovigilance analysis of preCOVID19 reports
This analysis of the FAERS database found use of hydroxychloroquine and chloroquine was associated with a higher reporting rate of major CV adverse events, including cardiomyopathy (reporting OR 29.0), QT prolongation (4.5), cardiac arrhythmias (2.2) and heart failure (2.2). (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - September 24, 2020 Category: Consumer Health News Source Type: news

COVID-19: Analysis reveals heart-related side effects of hydroxychloroquine, chloroquine
In the analysis of real-world data from the Food and Drug Administration Adverse Events Reporting System, a global database of post-marketing safety reports, hydroxychloroquine and chloroquine were associated with higher rates of various cardiovascular problems, including life-threatening heart rhythm events, heart failure, and damage to the heart muscle itself (termed cardiomyopathy). (Source: The Economic Times)
Source: The Economic Times - September 22, 2020 Category: Consumer Health News Source Type: news

Fighting cardiovascular disease with acne drug
(European Molecular Biology Laboratory) Researchers from the European Molecular Biology Laboratory (EMBL) in Heidelberg and Stanford University have found the cause of dilated cardiomyopathy - a leading cause of heart failure - and identified a potential treatment for it: a drug already used to treat acne. The study was published on 8 September in Cell Reports. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 8, 2020 Category: International Medicine & Public Health Source Type: news

14-3-3 binding creates a memory of kinase action by stabilizing the modified state of phospholamban
The cardiac membrane protein phospholamban (PLN) is targeted by protein kinase A (PKA) at Ser16 and by Ca2+/calmodulin-dependent protein kinase II (CaMKII) at Thr17. β-Adrenergic stimulation and PKA-dependent phosphorylation of Ser16 acutely stimulate the sarcoplasmic reticulum calcium pump (SERCA) by relieving its inhibition by PLN. CaMKII-dependent phosphorylation may lead to longer-lasting SERCA stimulation and may sustain maladaptive Ca2+ handling. Here, we demonstrated that phosphorylation at either Ser16 or Thr17 converted PLN into a target for the phosphoadaptor protein 14-3-3 with different affinities. 14-3-3 ...
Source: Signal Transduction Knowledge Environment - August 31, 2020 Category: Science Authors: Menzel, J., Kownatzki-Danger, D., Tokar, S., Ballone, A., Unthan-Fechner, K., Kilisch, M., Lenz, C., Urlaub, H., Mori, M., Ottmann, C., Shattock, M. J., Lehnart, S. E., Schwappach, B. Tags: STKE Research Articles Source Type: news

Study finds asymptomatic Chagas patients are at a high risk for cardiac disease
(University of Colorado Anschutz Medical Campus) People living with Chagas disease without symptoms or signs of cardiac injury are at high risk of developing cardiomyopathy, a progressive heart disease, and the risk more than doubled among patients with acute infections, according to a new study from the University of Colorado School of Medicine at the Anschutz Medical Campus. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - August 31, 2020 Category: Infectious Diseases Source Type: news

Preparticipation CV Screening: Who Gets the Red Card? Preparticipation CV Screening: Who Gets the Red Card?
Which cardiac conditions are disqualifying for kids who play sports? From hypertrophic cardiomyopathy to heart transplant, Mayo Clinic's Jonathan Johnson and Bernard Gersh have answers that may surprise you.Mayo Clinic (Source: Medscape Orthopaedics Headlines)
Source: Medscape Orthopaedics Headlines - August 12, 2020 Category: Orthopaedics Tags: Cardiology Commentary Source Type: news

What Are Common Fatty Acid Oxidation Metabolic Disorders?
Discussion All cells and particularly their mitochondria need an energy source. Glucose is one of the most common ones, but also fatty acids, lactate, pyruvate, ketones, and amino acids. Fatty acids are formed with a carboxylic acid with a long aliphatic carbon chain usually with even numbers of carbon atoms (usually 4-28 most commonly). Most are unbranched and in foods are usually found in the form of esters. Fatty acids are important energy sources for the heart (50-70%) but also skeletal muscle where resting muscle uses both glucose and fatty acids. During fasting or increased stress fatty acids become a major source o...
Source: PediatricEducation.org - July 27, 2020 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

UCalgary research study finds MRI effective in predicting major cardiac events
(University of Calgary) An international study led by Dr. James White, a clinician and researcher at the University of Calgary finds magnetic resonance imaging can be used to predict major cardiac events for people diagnosed dilated cardiomyopathy. White's study confirms about 40 per cent of patients with DCM have scarring patterns on their heart muscle which can be seen with MRI. These patterns are associated with higher risk of future heart failure admissions, life-threatening heart rhythms and death. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 15, 2020 Category: International Medicine & Public Health Source Type: news

Can COVID-19 Promote Takotsubo Syndrome? Perhaps Not Directly Can COVID-19 Promote Takotsubo Syndrome? Perhaps Not Directly
The prevalence of stress cardiomyopathy, perhaps underappreciated as part of the pandemic's toll, seemed to turn sharply upward in patients presenting with ACS in March and April.Medscape Medical News (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - July 13, 2020 Category: Cardiology Tags: Cardiology News Source Type: news

Incidence of Takotsubo Cardiomyopathy Up During COVID-19
FRIDAY, July 10, 2020 -- The incidence of Takotsubo cardiomyopathy has increased during the COVID-19 pandemic, according to a study published online July 9 in JAMA Network Open. Ahmad Jabri, M.D., from Cleveland Clinic Akron General, and colleagues... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - July 10, 2020 Category: Pharmaceuticals Source Type: news

' Broken Heart Syndrome' Has Risen During Pandemic: Study
THURSDAY, July 9, 2020 -- Doctors at one Ohio hospital system have discovered yet another possible consequence of the COVID-19 pandemic: More cases of " broken heart syndrome. " The condition -- which doctors call stress cardiomyopathy -- appears... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - July 9, 2020 Category: General Medicine Source Type: news

Comparing stress cardiomyopathy before, during COVID-19 pandemic
(JAMA Network) Patients with   acute coronary syndrome presenting during the COVID-19 pandemic were compared with patients presenting at times prior to the pandemic to investigate the incidence of stress cardiomyopathy during the pandemic in this observational study. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - July 9, 2020 Category: Infectious Diseases Source Type: news

Cardiomyopathy | Medscape Cardiomyopathy | Medscape
Review in-depth clinical information, latest medical news, and guidelines for management of various types of cardiomyopathy, including viral cardiomyopathy, infiltrative cardiomyopathy, postpartum cardiomyopathy, obstructive cardiomyopathy, primary cardiomyopathy, or idiopathic cardiomyopathy. Read articles about causes of cardiomyopathy symptoms and cardiomyopathy treatment. (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 8, 2020 Category: Consumer Health News Tags: Resource Center Source Type: news

Fat cells found to play a central role in renal failure-associated cardiomyopathy
(Marshall University Joan C. Edwards School of Medicine) New research from a team at the Marshall University Joan C. Edwards School of Medicine reveals the central role of fat cells in the systemic oxidant stress observed in renal failure-associated cardiomyopathy. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 29, 2020 Category: International Medicine & Public Health Source Type: news

Towbin receives National Institutes of Health research project grant
(Le Bonheur Children's Hospital) Jeffrey A. Towbin, MD, of Le Bonheur Children's Hospital and the University of Tennessee Health Science Center was awarded a Research Project Grant (R01) from the National Institutes of Health (NIH) with co-principal investigators Enkhsaikha Purevjav, MD, PhD and Lu Lu, MD, MS. He is lead principal investigator on the project 'Discovery of Modifier Genes in Cardiomyopathy..' (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 26, 2020 Category: International Medicine & Public Health Source Type: news

Emergency in a Dilated Cardiomyopathy Patient Emergency in a Dilated Cardiomyopathy Patient
A 76-year-old woman with dilated cardiomyopathy has a rapid heart rate associated with hypotension. What does her ECG show?Medscape Cardiology (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - June 18, 2020 Category: Cardiology Tags: Cardiology Clinical Case Source Type: news

High-Dose Tafamidis Boosts Survival in Cardiomyopathy High-Dose Tafamidis Boosts Survival in Cardiomyopathy
Tafamidis provided a significantly greater survival benefit in patients with transthyretin amyloid cardiomyopathy in the long-term extension of the landmark ATTR-ACT trial.Medscape Medical News (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - June 9, 2020 Category: Cardiology Tags: Cardiology News Source Type: news

Is Takotsubo Cardiomyopathy A Heart Attack
Is Takotsubo Cardiomyopathy a Heart Attack? (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - June 9, 2020 Category: General Medicine Source Type: news

Hypertrophic Cardiomyopathy
What Is the Life Expectancy of Someone with Hypertrophic Cardiomyopathy? (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - June 8, 2020 Category: General Medicine Source Type: news

PKCdelta causes sepsis-induced cardiomyopathy by inducing mitochondrial dysfunction
Sepsis-induced cardiomyopathy (SIC) is associated with increased patient mortality. At present, there are no specific therapies for SIC. Previous studies have reported increased reactive oxygen species (ROS) and mitochondrial dysfunction during SIC. However, a unifying mechanism remains to be defined. We hypothesized that PKCdelta is required for abnormal calcium handling and cardiac mitochondrial dysfunction during sepsis and that genetic deletion of PKCdelta would be protective. Polymicrobial sepsis induced by cecal ligation and puncture (CLP) surgery decreased the ejection fraction of wild-type (WT) mice but not PKCdelt...
Source: Current Awareness Service for Health (CASH) - June 4, 2020 Category: Consumer Health News Source Type: news

Diagnosis of Hypertrophic Cardiomyopathy: What Every Cardiologist Needs to Know Diagnosis of Hypertrophic Cardiomyopathy: What Every Cardiologist Needs to Know
Although it is the most common inherited monogenic cardiac disorder, affecting up to 0.5% of the population, there is a gap in the recognition of this condition.ACC.org (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - May 22, 2020 Category: Cardiology Tags: Cardiology Article Source Type: news

Functional Gains From Novel Agent for OHCM, Top-line Results Functional Gains From Novel Agent for OHCM, Top-line Results
Patients with obstructive hypertrophic cardiomyopathy showed consistent hemodynamic and functional gains on mavacamten, which targets cardiac myosin, in top-line results released by MyoKardia.Medscape Medical News (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - May 12, 2020 Category: Cardiology Tags: Cardiology News Source Type: news

Peninsula heart drug maker soars on positive late-stage clinical trial
Aiming to ask regulators early next year to approve its treatment for a potentially fatal heart condition, a Peninsula company's stock jumped more than 70% today on news that its drug passed a critical late-stage clinical trial. MyoKardia Inc. (NASDAQ: MYOK) of Brisbane said early data from a 251-patient, Phase III clinical trial indicates that people with a heart condition known as symptomatic, obstructive hypertrophic cardiomyopathy, or HCM, who were given the drug mavacamten over 30 weeks saw… (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - May 11, 2020 Category: Pharmaceuticals Authors: Ron Leuty Source Type: news