Hypertrophic Cardiomyopathy Risk Stratification Hypertrophic Cardiomyopathy Risk Stratification
Current and novel markers show promise for better accuracy of risk assessment for sudden cardiac death in patients with this condition.American College of Cardiology & Medscape (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - October 5, 2021 Category: Cardiology Tags: Cardiology Commentary Source Type: news

Peripartum Cardiomyopathy: From Genetics to Management Peripartum Cardiomyopathy: From Genetics to Management
Review our current understanding of the role of genetics in peripartum cardiomyopathy, a potentially life-threatening complication of pregnancy. What is the best approach to diagnosis and management?European Heart Journal (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 4, 2021 Category: Consumer Health News Tags: Cardiology Journal Article Source Type: news

Dilated cardiomyopathy associated with paraquat herbicide poisoning - Ahmad J, D'Angelo K, Rivas M, Mahal M, Nookala V, Kulakauskiene D, Makaryus AN.
Dilated cardiomyopathy is a subset of cardiomyopathies defined by reduced ejection fraction of less than 45% and a dilated left ventricle. While dilated cardiomyopathy is common, its etiology is not always readily evident. Paraquat is used as an herbicide ... (Source: SafetyLit)
Source: SafetyLit - September 27, 2021 Category: International Medicine & Public Health Tags: Poisoning Source Type: news

Reflections on Hypertrophic Cardiomyopathy Reflections on Hypertrophic Cardiomyopathy
A physician reflects on his career and the advances that have occurred in our understanding of hypertrophic cardiomyopathy in the 63 years since diagnosing his first patients with this condition.European Heart Journal (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 22, 2021 Category: Consumer Health News Tags: Cardiology Journal Article Source Type: news

Another Agent Raises Hopes for Obstructive HCM in Early Study Another Agent Raises Hopes for Obstructive HCM in Early Study
Hemodynamics improved significantly for patients with obstructive hypertrophic cardiomyopathy who took aficamten, the second myosin inhibitor to reach clinical trials, in a small randomized study.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - September 13, 2021 Category: Consumer Health News Tags: Cardiology News Source Type: news

PAUSE-SCD Strengthens Case for First-line VT Ablation Before ICD PAUSE-SCD Strengthens Case for First-line VT Ablation Before ICD
In the first VT-ablation trial of its kind in Asia and the first to offer insights for nonischemic cardiomyopathy, VT suppression and survival were superior when ablation preceded ICD implantation.Medscape Medical News (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - August 16, 2021 Category: Cardiology Tags: Cardiology News Source Type: news

' Abandoned' Man Dies in Hospital Waiting Room, Lawsuit Says'Abandoned' Man Dies in Hospital Waiting Room, Lawsuit Says
The 596-bed WellSpan York Hospital in Pennsylvania later determined that Terry Odoms, a 72-year-old Marine Corps and Vietnam veteran, died of ischemic cardiomyopathy.Associated Press (Source: Medscape Critical Care Headlines)
Source: Medscape Critical Care Headlines - August 6, 2021 Category: Intensive Care Tags: Emergency Medicine News Source Type: news

Managing Hypertrophic Cardiomyopathy: New Guidelines and Drugs Managing Hypertrophic Cardiomyopathy: New Guidelines and Drugs
Cardiologist Christopher DeSimone speaks with Steve Ommen about new AHA/ACC guidelines, emerging treatments, and the importance of focused HCM care.Mayo Clinic (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - August 2, 2021 Category: Cardiology Tags: Cardiology Commentary Source Type: news

Lawn mower versus left ventricular assist device: a case of traumatic coronary injury - Rao VN, Fudim M, Griffin A, Rymer JA, Jones WS, Koweek LMH, Smith TP, Marin D, DeVore AD.
A 77-year-old man with history of ischemic cardiomyopathy and left ventricular assist device (LVAD) presented with  abdominal pain after a lawn mower accident. Examination and imaging revealed a displaced LVAD driveline and a pericardial hematoma secondar... (Source: SafetyLit)
Source: SafetyLit - July 30, 2021 Category: International Medicine & Public Health Tags: Engineering, Physics, Structural Soundness and Failure Source Type: news

Study IDs risk factors for irregular heartbeats in hypertrophic cardiomyopathy patients
(University of Virginia Health System) The new research will help doctors identify, treat and prevent dangerous atrial fibrillation in patients with hypertrophic cardiomyopathy, a common heart condition. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - July 15, 2021 Category: International Medicine & Public Health Source Type: news

Methamphetamine-Linked Heart Failure Up in California
WEDNESDAY, July 14, 2021 -- From 2008 to 2018, there was a sharp increase in methamphetamine-associated cardiomyopathy/heart failure (MethHF) hospitalizations and related costs in California, according to a study published online July 14 in... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - July 14, 2021 Category: Pharmaceuticals Source Type: news

Teen, Parent Response Explored for Cardiomyopathy Genetic Tests
TUESDAY, July 13, 2021 -- Parents with unaffected children and positive predictive cardiomyopathy genetic testing results are more likely to experience negative emotions about the results, but they have better family functioning scores, according to... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - July 13, 2021 Category: Pharmaceuticals Source Type: news

Personalized medicine for cats with heart disease
(University of California - Davis) Veterinarians at the University of California, Davis, have found that a cat's DNA alters how it responds to a life-saving medication used to treat hypertrophic cardiomyopathy, or HCM, a heart disease that affects 1 in 7 cats. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 6, 2021 Category: International Medicine & Public Health Source Type: news

Genome-wide Association for HF: From Discovery to Clinical Use Genome-wide Association for HF: From Discovery to Clinical Use
A new GWAS study has identified a a polygenic risk score that contributes to dilated cardiomyopathy, opening the door to clinical use of these scores for determining HF or DCM progression.European Heart Journal (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - June 23, 2021 Category: Consumer Health News Tags: Cardiology Journal Article Source Type: news

High stress may make ‘broken heart syndrome’ more likely, study finds
Condition also known as takotsubo cardiomyopathy is brought on by an acute emotional shockTwo molecules associated with high stress levels have been implicated in the development of broken heart syndrome, a condition that mainly affects post-menopausal women and is usually brought on by severe stress, such as the loss of a loved one.The syndrome, formally known as takotsubo cardiomyopathy, is characterised by weakening of the heart ’s main pumping chamber and was first identified in 1990 in Japan. It looks and sounds like a heart attack and is consequently often confused for one.Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - June 20, 2021 Category: Science Authors: Natalie Grover Science correspondent Tags: Medical research Science Biology Heart attack UK news Health Society Source Type: news

Nuevocor closes US$24M Series A Financing to Advance Novel Gene Therapies for Cardiomyopathies
SINGAPORE, June 18, 2021 -- (Healthcare Sales & Marketing Network) -- Nuevocor, a preclinical-stage biotech company specializing in gene therapy for cardiomyopathies, has announced the completion of an oversubscribed $24 million Series A financing round. ... Biopharmaceuticals, Cardiology, Venture Capital Nuevocor, dilated cardiomyopathy, cardiomyopathy (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - June 18, 2021 Category: Pharmaceuticals Source Type: news

ACS Nano: CNIC scientists describe a possible disease-causing mechanism in hypertrophic cardiomyopathy
(Centro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.)) A team led by Dr. Jorge Alegre-Cebollada has shown, for the first time, an association between hypertrophic cardiomyopathy and mechanical alterations to a component of the contractile machinery of the heart (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 10, 2021 Category: International Medicine & Public Health Source Type: news

Mavacamten Boosts Quality of Life in Hypertrophic Cardiomyopathy Mavacamten Boosts Quality of Life in Hypertrophic Cardiomyopathy
More than twice as many patients with hypertrophic cardiomyopathy treated with the investigational agent mavacamten had a very large improvement in quality of life vs placebo in EXPLORER-HCM.Medscape Medical News (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - June 8, 2021 Category: Cardiology Tags: Cardiology News Source Type: news

Criteria for Determining Prevalence of Cirrhotic Cardiomyopathy Criteria for Determining Prevalence of Cirrhotic Cardiomyopathy
This study revealed that the prevalence of cirrhotic cardiomyopathy varies significantly according to the diagnostic criteria used.Liver International (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 14, 2021 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

ICER assessing mavacamten for hypertrophic cardiomyopathy
(Source: PharmacoEconomics and Outcomes News)
Source: PharmacoEconomics and Outcomes News - April 30, 2021 Category: Drugs & Pharmacology Source Type: news

SARS-CoV-2- or Pregnancy-related Cardiomyopathy? SARS-CoV-2- or Pregnancy-related Cardiomyopathy?
This case underscores the need to consider the possibility of SARS-CoV-2 infection in any pregnant woman who develops cardiomyopathy and pulmonary edema.Journal of Medical Case Reports (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - April 29, 2021 Category: Consumer Health News Tags: Family Medicine/Primary Care Journal Article Source Type: news

Study helps unravel why pregnant women develop heart failure similar to older patients
(University of Pennsylvania School of Medicine) Researchers at Penn Medicine have identified more genetic mutations that strongly predispose younger, otherwise healthy women to peripartum cardiomyopathy (PPCM), a rare condition characterized by weakness of the heart muscle that begins sometime during the final month of pregnancy through five months after delivery. PPCM can cause severe heart failure and often leads to lifelong heart failure and even death. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 20, 2021 Category: International Medicine & Public Health Source Type: news

Myocardial fibrosis in pathogenesis, diagnosis & treatment of hypertrophic cardiomyopathy
(Compuscript Ltd) In a new publication from Cardiovascular Innovations and Applications; DOI https://doi.org/10.15212/CVIA.2021.0008, Zeyi Cheng, Miaomiao Qi, Chengyuan Zhang and Yanxia Mao from Sichuan University, Sichuan, China, Second Hospital of Lanzhou University, Lanzhou, China and The Second Medical School of Lanzhou University, Lanzhou, China consider myocardial fibrosis in the pathogenesis, diagnosis, and treatment of hypertrophic cardiomyopathy. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 27, 2021 Category: International Medicine & Public Health Source Type: news

Tafamidis Should Be Accessible for All Patients With ATTR-CM Tafamidis Should Be Accessible for All Patients With ATTR-CM
Tafamidis, a daily, orally available medication, has proven highly effective in the treatment of transthyretin amyloid cardiomyopathy, but its high cost puts it out of reach of most patients.JACC: Heart Failure (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 26, 2021 Category: Consumer Health News Tags: Cardiology Journal Article Source Type: news

ECG Challenge: Hypotension in a Cardiomyopathy Patient ECG Challenge: Hypotension in a Cardiomyopathy Patient
A 69-year-old woman presents with shortness of breath and hypotension, with tests revealing pulmonary edema and acute renal insufficiency. What does the ECG show?Medscape Cardiology (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - March 23, 2021 Category: Cardiology Tags: Cardiology Clinical Case Source Type: news

U.S. Food and Drug Administration (FDA) Accepts Bristol Myers Squibb ’s Application for Mavacamten in Symptomatic Obstructive Hypertrophic Cardiomyopathy (oHCM)
PRINCETON, N.J.--(BUSINESS WIRE)-- March 19, 2021 -- Bristol Myers Squibb (NYSE: BMY) today announced that the U.S. Food and Drug Administration (FDA) has accepted its New Drug Application (NDA) for mavacamten, an investigational, novel, oral,... (Source: Drugs.com - New Drug Applications)
Source: Drugs.com - New Drug Applications - March 19, 2021 Category: Drugs & Pharmacology Source Type: news

The poisoned heart: a case of Takotsubo cardiomyopathy induced by carbon monoxide poisoning - Lakhani M, Alkhero M, Bains N, Steele R, Abdelmalik R.
BACKGROUND: Carbon monoxide is a common environmental toxin, and some patients present with features of cardiac injury in addition to the noxious effects of carbon monoxide poisoning. A very small fraction of those have a transient left ventricular apical ... (Source: SafetyLit)
Source: SafetyLit - March 12, 2021 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

Exploring pieces of heart muscle that fail to compact
(University of Houston) Of those diagnosed with a " spongy heart, " 47% will die. University of Houston pharmacologist Mingfu Wu has been awarded $2.5 million from the National Heart, Lung, and Blood Institute to explore the cause of and therapeutic treatment for the heart disease officially called left ventricular non-compaction cardiomyopathy (LVNC). (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 4, 2021 Category: International Medicine & Public Health Source Type: news

FSU College of Medicine researcher develops new possibilities to prevent sudden cardiac death
(Florida State University) Stephen Chelko, an assistant professor of biomedical sciences at the Florida State University College of Medicine, has developed a better understanding of the pathological characteristics behind arrhythmogenic cardiomyopathy, as well as promising avenues for prevention. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 17, 2021 Category: International Medicine & Public Health Source Type: news

Mayo Clinic Q and A: Hypertrophic cardiomyopathy
DEAR MAYO CLINIC: My sister was just told she has hypertrophic cardiomyopathy. I've heard of that causing sudden death in athletes. She says she feels fine and doesn't need treatment now, so is she at low risk? What does her diagnosis mean for me and my family? ANSWER: Hypertrophic cardiomyopathy is a fairly common heart condition, affecting [...] (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - February 3, 2021 Category: Databases & Libraries Source Type: news

Heart defect that kills thousands without warning could be spotted early by a blood test 
Hypertrophic cardiomyopathy, which causes the heart muscle to abnormally thicken and beat out of control, is the leading cause of cardiac arrest and sudden death in under-40s. (Source: the Mail online | Health)
Source: the Mail online | Health - January 31, 2021 Category: Consumer Health News Source Type: news

AHA/ACC Urge Shared Decisions in Hypertrophic Cardiomyopathy
MONDAY, Dec. 21, 2020 -- Updated clinical practice guidelines from the American Heart Association/American College of Cardiology, published online Nov. 20 in Circulation, emphasize shared decision-making in the management of hypertrophic... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - December 21, 2020 Category: Pharmaceuticals Source Type: news

Joelle's journey to a new heart
Cardiomyopathy is a medical term for a number of genetic and nongenetic diseases involving the heart muscle that adversely affect the heart's mechanical pumping function and its electrical system. It can occur in people of all ages, races or genders, and it is a frequent cause of sudden cardiac arrest and sudden cardiac death. For [...] (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - December 8, 2020 Category: Databases & Libraries Source Type: news

What Areas of the Physical Examination are Important in the Pre-participation Physical Examination?
Discussion Participation in organized or non-organized, recreational to elite sports activities can provide excellent recreational and leisure time activities and improve physical and mental health for participants. The Aspen Institute in 2018 reported that more kids are being physically active, more are trying different sports, and multisports play is increasing rather than strict specialization. Unfortunately they note that there is an economic inequality with children from lower-socioeconomic circumstances playing less organized sports. About 70% of children and youth participate in an individual or team sport, but unfo...
Source: PediatricEducation.org - December 7, 2020 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

New HCM Guidelines Make Shared Decision-making Top Priority New HCM Guidelines Make Shared Decision-making Top Priority
An updated guideline for patients with hypertrophic cardiomyopathy (HCM)'puts the patient front and center in the shared decision-making process,'according to a member of the writing committee.Medscape Medical News (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - November 20, 2020 Category: Cardiology Tags: Cardiology News Source Type: news

Hypertrophic cardiomyopathy guideline encourages shared decision-making
(American College of Cardiology) The American Heart Association and the American College of Cardiology today released an updated guideline for managing patients with hypertrophic cardiomyopathy (HCM). The guideline encourages shared decision-making between the clinician and patient as essential when determining treatment course and updates recommendations for sudden cardiac death (SCD) risk assessment and HCM center referrals based on the latest evidence. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 20, 2020 Category: International Medicine & Public Health Source Type: news

Importance of mitochondrial-related genes in dilated cardiomyopathy
(Compuscript Ltd) Importance of Mitochondrial-Related Genes in Dilated Cardiomyopathy Based on Bioinformatics Analysis. In a new publication from Cardiovascular Innovations and Applications; DOI https://doi.org/10.15212/CVIA.2019.0588, Yukuan Chen, Xiaohui Wu, Danchun Hu and Wei Wang, from the Shantou University Medical College, Shantou, China and Second Affiliated Hospital of Shantou University Medical College, Shantou, China consider the importance of mitochondrial-related genes in dilated cardiomyopathy. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 19, 2020 Category: International Medicine & Public Health Source Type: news

Cellular pathway of genetic heart disease similar to neurodegenerative disease
(Mayo Clinic) Research on a genetic heart disease has uncovered a new and unexpected mechanism for heart failure. This landmark discovery found a correlation between the clumping of RNA-binding proteins long linked to neurodegenerative disease and the aggregates of protein found in the heart tissue of patients with RBM20 dilated cardiomyopathy. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 18, 2020 Category: International Medicine & Public Health Source Type: news

A change of heart -- new drug for HCM reduces heart mass
(Michigan Medicine - University of Michigan) For the first time, a medication has impacted heart muscle thickness and function for patients with the most common inherited heart condition, hypertrophic cardiomyopathy, rather than simply addressing their symptoms. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 16, 2020 Category: International Medicine & Public Health Source Type: news

Cellular pathway of genetic heart disease similar to neurodegenerative disease
ROCHESTER, Minn. -- Research on a genetic heart disease has uncovered a new and unexpected mechanism for heart failure. This landmark discovery found a correlation between the clumping of RNA-binding proteins ? long linked to neurodegenerative disease ? and the aggregates of protein found in the heart tissue of patients with RBM20 dilated cardiomyopathy. Dilated [...] (Source: Mayo Clinic Minnesota News)
Source: Mayo Clinic Minnesota News - November 13, 2020 Category: Hospital Management Source Type: news

AHA: Mavacamten May Treat Hypertrophic Cardiomyopathy
THURSDAY, Nov. 12, 2020 -- Compared with placebo, mavacamten (Mava), a novel inhibitor of cardiac myosin, for 30 weeks leads to improvement in left ventricular (LV) hypertrophy and markers of left-sided filling pressures in patients with obstructive... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - November 12, 2020 Category: Pharmaceuticals Source Type: news

New Hope for a Rare Heart Condition
THURSDAY, Nov. 12, 2020 -- An experimental drug might improve heart function for people with a condition called obstructive hypertrophic cardiomyopathy, a new study finds. Hypertrophic cardiomyopathy is a thickening of heart muscle that can... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - November 12, 2020 Category: General Medicine Source Type: news

Penn State's Journey Brown retiring from football due to heart condition
Penn State running back Journey Brown will retire from football after being diagnosed with a heart ailment known as hypertrophic cardiomyopathy. (Source: Reuters: Health)
Source: Reuters: Health - November 12, 2020 Category: Consumer Health News Source Type: news

At What Age Does Hypertrophic Cardiomyopathy Develop?
Title: At What Age Does Hypertrophic Cardiomyopathy Develop?Category: Diseases and ConditionsCreated: 11/9/2020 12:00:00 AMLast Editorial Review: 11/9/2020 12:00:00 AM (Source: MedicineNet Heart General)
Source: MedicineNet Heart General - November 9, 2020 Category: Cardiology Source Type: news

Study reinforces drug's potential to treat hypertrophic cardiomyopathy
(Washington State University) WSU research sheds new light on a molecule that may be used to treat heart conditions that can lead to stroke, heart attack and other forms of heart disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 27, 2020 Category: International Medicine & Public Health Source Type: news

Oct 23 2020 This Week in Cardiology Oct 23 2020 This Week in Cardiology
COVID, tocilizumab, hypertrophic cardiomyopathy, cerebral microbleeds, and surrogate endpoints are the topics discussed by John Mandrola, MD, in this week ’ s podcasttheheart.org on Medscape (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 23, 2020 Category: Consumer Health News Tags: Cardiology Commentary Source Type: news

What Causes Hypertrophic Cardiomyopathy?
Title: What Causes Hypertrophic Cardiomyopathy?Category: Diseases and ConditionsCreated: 10/21/2020 12:00:00 AMLast Editorial Review: 10/21/2020 12:00:00 AM (Source: MedicineNet Heart General)
Source: MedicineNet Heart General - October 21, 2020 Category: Cardiology Source Type: news

Surgery Still Best Option in Obstructive HCM Surgery Still Best Option in Obstructive HCM
Promising results for a novel drug should not push surgical options aside for patients with obstructive hypertrophic cardiomyopathy, argue two surgeons.theheart.org on Medscape (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - October 15, 2020 Category: Cardiology Tags: Cardiology Commentary Source Type: news

Cell Therapy for Anthracycline Cardiomyopathy Safe, Feasible Cell Therapy for Anthracycline Cardiomyopathy Safe, Feasible
In a small phase 1 study, administration of allogeneic bone marrow-derived mesenchymal stromal cells was safe and feasible in patients with anthracycline-induced cardiomyopathy heart failure.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - October 2, 2020 Category: Consumer Health News Tags: Cardiology News Source Type: news

Cardiovascular adverse events associated with hydroxychloroquine and chloroquine: A comprehensive pharmacovigilance analysis of preCOVID19 reports
This analysis of the FAERS database found use of hydroxychloroquine and chloroquine was associated with a higher reporting rate of major CV adverse events, including cardiomyopathy (reporting OR 29.0), QT prolongation (4.5), cardiac arrhythmias (2.2) and heart failure (2.2). (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - September 24, 2020 Category: Consumer Health News Source Type: news