Can a common heart condition cause sudden death?
(Gladstone Institutes) About one person out of 500 has a heart condition known as hypertrophic cardiomyopathy (HCM). This condition causes thickening of the heart muscle and results in defects in the heart's electrical system. Under conditions of environmental stress such as exercise, HCM can result in sudden death. In other cases, patients may go undiagnosed, with their heart function declining gradually over decades. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - September 20, 2018 Category: Biology Source Type: news

Tafamidis Treats Transthyretin Amyloid Cardiomyopathy
TUESDAY, Sept. 18, 2018 -- In patients with transthyretin amyloid cardiomyopathy, treatment with tafamidis reduces all-cause mortality and cardiovascular-related hospitalizations versus placebo, according to a study published in the Sept. 13 issue... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - September 18, 2018 Category: Pharmaceuticals Source Type: news

AHA: Update on Diagnosis, Tx for Chagas Cardiomyopathy
TUESDAY, Sept. 11, 2018 -- Health care providers need to be equipped to recognize, diagnose, and treat Chagas disease, which is growing in prevalence in the United States, according to an American Heart Association (AHA) scientific statement... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - September 11, 2018 Category: Pharmaceuticals Source Type: news

Changes in mitochondrial DNA control how nuclear DNA mutations are expressed in cardiomyopathy
(Children's Hospital of Philadelphia) Differences in the DNA within the mitochondria, the energy-producing structures within cells, can determine the severity and progression of heart disease caused by a nuclear DNA mutation. When combined with a mutation in nuclear DNA in animals, one mitochondrial DNA variant greatly worsened heart disease, while a different variant had a protective effect. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 11, 2018 Category: International Medicine & Public Health Source Type: news

Health Care Heroes award winner: Craig Smith, Second Chance Fundraising
Craig Smith  is a 2018 Health Care Heroes award winner in the volunteer category. Here's his story: Dressing up as a giant heart wasn’t what Craig Smith first envisioned when he decided he wanted to give back to the community that supported him after he had a heart transplant. In his early 20s, Smith was d iagnosed with viral cardiomyopathy, a degenerative heart disorder. In 2015, he underwent a successful heart transplant procedure at Allegheny General Hospital. While living in Johnstown, Smith… (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - September 7, 2018 Category: Pharmaceuticals Authors: Richard Cerilli Source Type: news

Health Care Heroes award winner: Craig Smith, Second Chance Fundraising
Craig Smith  is a 2018 Health Care Heroes award winner in the volunteer category. Here's his story: Dressing up as a giant heart wasn’t what Craig Smith first envisioned when he decided he wanted to give back to the community that supported him after he had a heart transplant. In his early 20s, Smith was d iagnosed with viral cardiomyopathy, a degenerative heart disorder. In 2015, he underwent a successful heart transplant procedure at Allegheny General Hospital. While living in Johnstown, Smith… (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - September 7, 2018 Category: Biotechnology Authors: Richard Cerilli Source Type: news

Woman, 38, is left with a 'broken heart' after taking part in Zumba
Cardiologists in Michigan diagnosed the unnamed woman with takotsubo cardiomyopathy, also known as broken heart syndrome. The condition is usually triggered by a horrible shock. (stock) (Source: the Mail online | Health)
Source: the Mail online | Health - September 5, 2018 Category: Consumer Health News Source Type: news

Inhibiting NF- & #954;B improves heart function in a mouse model of Duchenne muscular dystrophy
(Medical University of South Carolina) In an August 24, 2018 article in Nature Communications, investigators at the Medical University of South Carolina and Ohio State University report that nuclear factor kappa B (NF-κB) down-regulates calcium genes, contributing to cardiomyopathy in Duchenne muscular dystrophy (DMD). Murine data show cardiomyocyte ablation of NF-κB rescues cardiac function. NF-κB promotes global chromatin landscape changes that repress calcium mobilization in DMD. This mechanism also contributes to skeletal muscle dysfunction. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 30, 2018 Category: International Medicine & Public Health Source Type: news

ATTR-ACT: Tafamidis Reduces Mortality in Amyloid Cardiomyopathy ATTR-ACT: Tafamidis Reduces Mortality in Amyloid Cardiomyopathy
A drug that binds transthyretin reduced all-cause mortality and cardiovascular hospitalizations and slowed decline in functional capacity in patients with transthyretin amyloid cardiomyopathy.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - August 27, 2018 Category: Consumer Health News Tags: Cardiology News Source Type: news

Drug reduces deaths and hospitalizations from underdiagnosed form of heart failure
(Columbia University Irving Medical Center) A study led by Columbia University cardiologist Mathew Maurer showed that tafamidis reduced deaths from a type of heart failure called transthyretin amyloid cardiomyopathy. The drug could be one of the first effective treatments for the disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 27, 2018 Category: International Medicine & Public Health Source Type: news

Epigenetic reprogramming of human hearts found in congestive heart failure
(University of Alabama at Birmingham) Congestive heart failure is a terminal disease that affects nearly 6 million Americans. Yet its management is limited to symptomatic treatments because the causal mechanisms of congestive heart failure are not known. Researchers have now described an underlying mechanism that reprograms the hearts of patients with ischemic cardiomyopathy, a process that differs from patients with other forms of heart failure. This points the way toward future personalized care. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 9, 2018 Category: International Medicine & Public Health Source Type: news

Guns and Death; Diabetes Typing: It's PodMed Double T! (with audio)
(MedPage Today) -- This week ' s topics include caliber of bullets and handgun deaths, a novel agent for dilated cardiomyopathy, getting genomic screening into clinical practice, and new diabetes subtypes based on continuous glucose monitoring. (Source: MedPage Today Nephrology)
Source: MedPage Today Nephrology - August 4, 2018 Category: Urology & Nephrology Source Type: news

A protein could be key to preserving heart function in Duchenne muscular dystrophy
(American Heart Association) The brain-derived neurotrophic factor protein, known to be vital for brain function, might hold the key for preserving heart function in children and young adults with Duchenne muscular dystrophy.Heart failure often kills Duchenne patients early in life and there is no effective treatment.Developing therapies designed to activate or supplement brain-derived neurotrophic factor could give new hope to patients at risk for Duchenne cardiomyopathy. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 1, 2018 Category: International Medicine & Public Health Source Type: news

Rapid Improvement of Dilated Cardiomyopathy With Anakinra
TUESDAY, July 31, 2018 -- In a report published online July 31 in the Annals of Internal Medicine, doctors describe the case of a patient with dilated cardiomyopathy who experienced rapid clinical improvements with use of anakinra, the recombinant... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - July 31, 2018 Category: Pharmaceuticals Source Type: news